Deshmukh PS et al. · 2016
Researchers exposed male Fischer rats to microwave radiation for 90 days at 900, 1800, and 2450 MHz to investigate effects on cognitive function, heat shock protein 70 (HSP70) levels, and DNA damage in the brain. Cognitive function was tested using the elevated plus maze and Morris water maze, HSP70 levels were measured by ELISA, and DNA damage was assessed using alkaline comet assay. The results suggest that low-level microwave exposure at these frequencies may lead to hazardous effects on the brain.
(E) Barthélémy A et al. · 2016
Researchers exposed male Sprague Dawley rats for 15 minutes at 0, 1.5, or 6 W/kg, or for 45 minutes at 6 W/kg, to radiofrequency electromagnetic fields. Memory, emotionality, and locomotion were tested using fear conditioning, the elevated plus maze, and the open field. Long-term memory was reduced and cytosolic GFAP was increased in the hippocampus and in the olfactory bulb at 6 W/kg. No MBP or Aβ1–40 expression modification was shown. The study suggests that RF EMF-induced astrogliosis had functional consequences on memory but did not demonstrate that it was secondary to neuronal damage.
Engels S, N-L Schneider, N Lefeldt, et al. · 2015
Yao L, Li Y, Knapp J, Smith P. · 2015
Researchers exposed Schwann cells to an electric field of 100 mV/mm and performed RNA sequencing to compare gene expression with unstimulated cells. They identified 1,045 up-regulated and 1,636 down-regulated genes using a fold-change threshold of 1.2 and a q-value below 0.05. KEGG pathway analysis revealed 21 down-regulated and 10 up-regulated pathways, with differentially expressed genes involved in actin cytoskeleton regulation, focal adhesion, and PI3K-Akt signaling.
Liu Y, Liu W-B, Liu K-J, Ao L, Cao J, Zhong JL, Liu J-Y · 2015
Li Y, Wang X, Yao L · 2015
Researchers investigated how oligodendrocyte precursor cells migrate in electric fields. The cells moved toward the anode, and their directedness and displacement increased significantly when the field strength was raised from 50 to 200 mV/mm. Electric fields did not significantly change the cells' migration speed. Transcriptome analysis revealed upregulation of the MAPK pathway at 200 mV/mm and downregulation of chemotaxis-related genes.
Prato FS · 2015
The author reports that ELF-MF exposure conditions were identified that can either increase or decrease nociception in snails and mice. The research also found that ELF-MF can induce analgesia in humans. The 1984 discovery in mice showed that ELF-MF could reduce opiate-induced analgesia. The author's team pioneered the use of electroencephalography and magnetic resonance imaging to monitor effects during exposure. The article presents the author's contributions and is not intended as a balanced review.
Unknown authors · 2015
Researchers exposed the cortex of juvenile and young adult rats to 1457 MHz RF at 2.0 W/kg for 50 minutes. They measured blood-brain barrier permeability in the pia mater using intravital fluorescence microscopy. No significant difference in dye extravasation was found between exposed and sham-exposed groups, and no albumin leakage was detected after exposure.
Unknown authors · 2015
Researchers exposed transgenic 5xFAD and wild-type mice to 1950 MHz RF-EMF for eight months at a SAR of 5 W/kg, two hours per day, five days per week. The exposure significantly reduced Aβ plaques, APP, and APP carboxyl-terminal fragments in the whole brain including hippocampus and entorhinal cortex, and reduced the Aβ42/Aβ40 ratio in the hippocampus of Tg-5xFAD mice. RF-EMF inhibited parenchymal BACE1 expression and neuroinflammation in the transgenic mice. The treatment rescued memory impairment in the transgenic mice. Gene profiling showed that five Aβ-related genes were significantly altered in transgenic mice, with opposite expression patterns compared with wild-type mice.
Unknown authors · 2015
Current evidence indicates that exposure at levels found in the environment may particularly alter the receptor organs to orient in the magnetic field of the earth. These results could have important implications for migratory birds and insects, especially in urban areas. These results could also apply to birds and insects in natural and protected areas where there are powerful base station emitters of radiofrequencies. Therefore, more research on the effects of electromagnetic radiation in nature is needed to investigate this emerging threat.
Yoon S, Choi JW, Lee E, Ahn H, Kim HS, Choi HD, Kim N. · 2015
Among ipsilateral users, the adjusted odds ratios for lifetime years of use and cumulative hours of use were 1.25 (95% CI 0.55 to 2.88) and 1.77 (95% CI 0.32 to 1.84), respectively. The authors concluded that the results do not support the hypothesis that mobile phone use increases glioma risk, but suggest further evaluation for long-term users.
Söderqvist F, Carlberg M, Hardell L · 2015
Researchers conducted a single-blinded randomized counterbalanced study with 24 healthy subjects aged 18–30 years who underwent three exposure conditions. The study tested whether microwaves from an 890-MHz phone-like signal at SAR10G of 2 W/kg and 0.2 W/kg versus sham gave acute effects on brain-shielding barriers using blood serum biomarkers. Over time, statistically significant variations were found for TTR and β-trace protein, but no difference was found between exposure conditions and no interaction between exposure condition and time of blood sampling. The study concluded it failed to show any acute clinically or statistically significant effect of short-term microwave exposure on serum levels of S100β, TTR, and β-trace protein with follow-up limited to two hours.
Shrestha M, Raitanen J, Salminen T, Lahkola A, Auvinen A · 2015
A case-control study in Finland included 80 pituitary tumor cases and 240 matched controls. Mobile phone use history was obtained via structured interview and analyzed with conditional logistic regression. Regular mobile phone users showed a reduced odds ratio of 0.39 (95% CI 0.21-0.72) compared to never or non-regular users, though the authors noted this may reflect methodological limitations. No increased risk was found after 10 or more years since first use (OR 0.69, 95% CI 0.25-1.89), nor in relation to duration, cumulative hours, or cumulative number of calls, with similar results for analog and digital phones. The authors noted no excess risk for short- or medium-term use, but uncertainties remained for longer duration due to few participants reporting use beyond 10 years.
Schoeni A, Roser K, Röösli M. · 2015
In a cross-sectional study, 439 adolescents completed questionnaires about mobile phone use at night and health, and 233 provided operator-recorded use data. Standardized computerized cognitive tests assessed memory and concentration capacity. Adolescents who reported being awakened at least once a month had higher odds of daytime tiredness (OR 1.86) and rapid exhaustibility (OR 2.28). Similar associations were seen with objective operator-recorded data for tiredness (OR 1.63) and rapid exhaustibility (OR 2.32). Cognitive test performance was not related to nighttime mobile phone use.
Malkemper EP et al. · 2015
The researchers tested the wood mouse Apodemus sylvaticus for magnetoreception using a simple behavioural assay in which mice were allowed to build nests overnight in a visually symmetrical, circular arena. When plotted with respect to magnetic north, the nests were bimodally clustered in the northern and southern sectors, indicating the animals used magnetic cues. Wood mice exposed to a 0.9 to 5 MHz frequency sweep changed their preference from north-south to east-west. A constant frequency field tuned to the Larmor frequency (1.33 MHz) had no effect on mouse orientation. The study demonstrated magnetoreception in wood mice and provided first evidence for a radical-pair mechanism in a mammal.
Court-Kowalski S et al. · 2015
Researchers exposed mice to 900 MHz RF fields at 4 W/kg for 104 weeks, five days per week. Control mice were sham-exposed or freely moving in cages. No change in astrocytic GFAP immunostaining was found in exposed mice compared to controls.
Lai J et al. · 2015
Sixty adult male rats were randomly assigned to a sham group or a 50 Hz/100 µT ELF-EMF exposure group for 24 weeks. During the exposure period, body weight, food intake, and water intake were recorded and showed no differences between groups. Behavioral tests for anxiety, depression, cognition, and memory found no effects of ELF-EMF, and brain morphology and histology were unchanged.
Trunk A et al. · 2015
Researchers used a full factorial design with 25 participants performing a visual target detection task while recording reaction time and EEG. Target trials were divided into low and high probability sets based on the distance between consecutive targets. Caffeine further shortened reaction time in high-probability trials and decreased pre-target alpha amplitude, indicating higher arousal. UMTS exposure alone or combined with caffeine did not change reaction time or pre-stimulus oscillatory brain activity.
Sauter C et al. · 2015
Researchers conducted a double-blind cross-over study with 30 healthy young men exposed to TETRA signals at 1.5 W/kg and 6.0 W/kg and sham. Exposure lasted 2.5 hours at 385 MHz with specific absorption rates of 1.5 and 6.0 W/kg. Attention was unchanged in two of three tasks, while working memory showed significant changes in two of four subtasks. 5 out of 35 tested parameters showed significant results, four of which indicated improved performance. Mood, well-being, and subjective somatic complaints were not affected by TETRA exposure.
Salunke BP, Umathe SN, Chavan JG. · 2015
Researchers exposed mice to 2.45 GHz HF-EMF for 60 minutes per day for 7 or 30 or 60 or 90 or 120 days. Anxiety-like behavior was assessed with the elevated plus maze, open field test, and social interaction test; OCD-like behavior with marble burying; and depression-like behavior with the forced swim test and tail suspension test. The study found no evidence that HF-EMF exposure produced anxiety, OCD, or depression-like behavior in mice up to 120 days.
Malek F, Rani KA, Rahim HA, Omar MH · 2015
The study aimed to determine whether short-term exposure at 1 V/m to typical GSM and UMTS signals affects cognitive performance and physiological parameters. The sample included 200 subjects, with 50.0% reporting idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) and 50.0% non-IEI-EMF. No statistically significant differences were found between real exposure and sham exposure for cognitive performance or physiological effects in either group (P’s > 0.05).
Gupta N, Goyal D, Sharma R, Arora KS · 2015
The study aimed to evaluate the effects of long-term mobile phone usage on auditory brainstem evoked responses. Researchers conducted a retrospective cross-sectional case-control study with 100 healthy subjects aged 18 to 30, including 67 long-term GSM mobile phone users and 33 non-user controls. No significant difference was found in latencies, interpeak latencies, and amplitudes of ABR waves between the groups.
Zheng F et al. · 2015
Fatigue was significantly associated with years of MP usage and daily duration of MP calls, while headache was significantly associated with daily duration of MP calls. After adjusting for confounders, only the association between fatigue and MP usage remained statistically significant, and no significant association was found between MP use and other physical symptoms.
Singh S, Mani KV, Kapoor N. · 2015
Sangun O, Dundar B, Darici H, Comlekci S, Doguc DK, Celik S · 2015
Researchers exposed female Wistar rats to a 2450 MHz electromagnetic field for one hour per day starting either prenatally or postnatally, with a sham-exposed control group. Prenatal exposure led to significantly lower daily mass gain and significantly later puberty. Brain and ovary total oxidant status and oxidative stress index were significantly increased in the prenatal group compared to the control group. Serum LH levels were increased in both prenatal and postnatal groups, while FSH and E2 did not differ among groups. Histological examinations showed no statistically significant differences between groups.
