6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 83% of 1,950 primary studies on brain & nervous system found biological effects from EMF exposure.

Of 1,950 studies examining brain & nervous system, 83% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextStudy Exposure Level in Context4.3 × 10⁻⁵ mGExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects documented below the Building Biology "No Concern" threshold (0.2 mG)FCC limit is 46.5 million times higher than this level

Research Overview

  • -When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects.
  • -This isn't a fringe concern or preliminary finding.
  • -This is the dominant scientific picture, and it deserves your attention.

When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects. This isn't a fringe concern or preliminary finding. This is the dominant scientific picture, and it deserves your attention. The documented effects span multiple systems within your nervous system.

Of 2,753 studies examining EMF effects on the brain and nervous system, approximately 84 percent found measurable biological effects.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database

Showing 2,030 studies

Effect of a single 30 min UMTS mobile phone‐like exposure on the thermal pain threshold of young healthy volunteers.

Vecsei Z, Csathó A, Thuróczy G, Hernádi I · 2013

Researchers tested the effects of UMTS RF EMF exposure on the thermal pain threshold of 20 young adult volunteers, measuring responses on the surface of the fingers. The exposure lasted 30 minutes and was applied to the head through a patch antenna, with SAR kept constant at 1.75 W/kg. Thermal pain thresholds were intact, but a reduced desensitization effect between repeated stimulations was observed on the contralateral side during genuine UMTS exposure. Subjective pain ratings were marginally decreased in the genuine exposure condition only.

Effect of electromagnetic radiation on discharge activity of neurons in the hippocampus CA1 in rats

Tong J, Chen S, Liu XM, Hao DM · 2013

Researchers recorded hippocampal CA1 neuron activity in rats exposed to 900 MHz electromagnetic radiation at 10 W/m2 using glass electrode extracellular recording and a polygraph. Discharge frequency of hippocampal CA1 neurons was reduced after exposure, though the change in scale was not obvious. Electromagnetic radiation might change the spontaneous discharge patterns of hippocampus CA1 region neurons, making the explosive discharge pattern increase obviously. The researchers suggested that these changes may lead to a decrease in the ability of learning and memory.

Spatial memory and learning performance and its relationship to protein synthesis of Swiss albino mice exposed to 10 GHz microwaves

Sharma A, Sisodia R, Bhatnagar D, Saxena VK · 2013

Researchers exposed Swiss albino mice to 10 GHz microwaves at a power density of 0.25 mW/cm2 for 2 hours per day for 30 days, then tested spatial memory using the Morris water maze test. Exposed mice showed statistically significant higher mean latency to reach the target quadrant compared to sham-exposed mice. A decrease in protein levels was also estimated in the whole brain of exposed mice compared to sham-exposed mice.

Effects of chronic exposure to radiofrequency electromagnetic fields on energy balance in developing rats

Pelletier A et al. · 2013

Researchers examined the effects of chronic RF-EMF exposure (900 MHz, 1 V m(-1)) on the main functions involved in body energy homeostasis, including feeding behaviour, sleep, and thermoregulatory processes. Thirteen juvenile male Wistar rats were exposed to continuous RF-EMF for 5 weeks and compared with 11 non-exposed animals. The frequency of rapid eye movement sleep episodes was greater in the exposed group independently of ambient temperature, with increases of 42.1% at 24 °C and 31.6% at 31 °C. Exposure also increased daytime food intake, and the researchers concluded that RF-EMF exposure can induce energy-saving processes without strongly disturbing the overall sleep pattern.

The Effects of 900 Megahertz Electromagnetic Field Applied in the Prenatal Period on Spinal Cord Morphology and Motor Behavior in Female Rat Pups

Odacı E et al. · 2013

Researchers exposed pregnant rats to 900 MHz electromagnetic fields for one hour daily between days 13 and 21 of pregnancy, then assessed the female pups' spinal cord tissue and motor behavior. The rotarod test showed a significant increase in motor functions in the EMF group pups (p=0.037), while the open field test found no difference between groups. Pathological changes were observed in the spinal cords of the EMF group pups, and the researchers suggested these changes may have led to the increase in motor activity.

Analysis of emotionality and locomotion in radio-frequency electromagnetic radiation exposed rats.

Narayanan SN et al. · 2013

Researchers exposed male adolescent rats to radio-frequency electromagnetic radiation at 900 MHz from an active mobile phone, then tested their emotionality and locomotion. In the elevated plus maze test, exposed rats showed significantly reduced open-arm entries, time on open arms, and distance on open arms, along with decreased rearing and grooming frequency. Total distance travelled and total arm entries did not differ significantly between exposed and control rats.

Effect of bluetooth headset and mobile phone electromagnetic fields on the human auditory nerve

Mandalà M et al. · 2013

Researchers conducted a study to verify whether Bluetooth devices reduce the auditory nerve effects seen with direct mobile phone electromagnetic field exposure, using the same experimental protocol as a prior investigation. Twelve patients underwent retrosigmoid vestibular neurectomy to treat definite unilateral Ménière's disease while being monitored with acoustically evoked CNAPs during direct mobile phone or Bluetooth headset exposure. Bluetooth electromagnetic fields did not produce any significant change in cochlear nerve activity, while mobile phone electromagnetic fields caused a significant decrease in CNAP amplitude and an increase in latency in all subjects.

The alteration of spontaneous low frequency oscillations caused by acute electromagnetic fields exposure

Lv B, Chen Z, Wu T, Shao Q, Yan D, Ma L, Lu K, Xie Y. · 2013

Eighteen subjects participated in a double-blind, crossover, randomized and counterbalanced experiment including real and sham exposure sessions. Resting-state fMRI signals were collected before and after exposure, with the radiation source placed close to the right ear. After real exposure, decreased ALFF values were found in the left superior temporal gyrus, left middle temporal gyrus, right superior temporal gyrus, right medial frontal gyrus, and right paracentral lobule.

Effects of long-term electromagnetic field exposure on spatial learning and memory in rats.

Hao D, Yang L, Chen S, Tong J, Tian Y, Su B, Wu S, Zeng Y · 2013

Researchers exposed 32 trained Wistar rats to 916 MHz, 10w/m2 electromagnetic field for 6 hours a day, 5 days a week, over 10 weeks, and tested their spatial learning and memory in an eight-arm radial maze each weekend. During weeks 4–5, the exposed rats had longer completion times and higher error rates than the control group, but during weeks 1–3 and 6–9 the two groups were close to each other. The researchers concluded that the 916 MHz EMF influenced learning and memory in rats to some extent in a period during exposure, and that the rats can adapt to long-term EMF exposure.

Maternal mobile phone exposure adversely affects the electrophysiological properties of Purkinje neurons in rat offspring

Haghani M, Shabani M, Moazzami K · 2013

Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.

Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-à-vis Genotoxicity in Brain of Fischer Rats

Deshmukh PS et al. · 2013

The study investigated possible DNA-damaging effects of low-level microwave radiation in the brains of male Fischer rats. Rats were exposed for 30 days at three frequencies: 900, 1800, and 2450 MHz, at specific absorption rates on the order of 10−4 W/kg. DNA damage in brain tissue was assessed using alkaline comet assay after the exposure period. The researchers concluded that low SAR microwave radiation at these frequencies may induce DNA strand breaks in brain tissue.

Food collection and response to pheromones in an ant species exposed to electromagnetic radiation

Cammaerts MC, Rachidi Z, Bellens F, De Doncker P · 2013

Researchers used the ant species Myrmica sabuleti to study how electromagnetic waves affect the insects' responses to pheromones and food collection. Workers' responses to trail, area-marking, and alarm pheromones were measured under normal conditions and then again while under the influence of electromagnetic waves. Under exposure, ants followed trails for only short distances, no longer arrived at marked areas, and no longer orientated themselves to a source of alarm pheromone. The number of ants collecting food increased only slightly and slowly, and after 180 hours of exposure their colonies deteriorated.

Pyramidal Cell Loss in the Cornu Ammonis of 32-day-old Female Rats Following Exposure to a 900 Megahertz Electromagnetic Field During Prenatal Days 13–21.

Baş O et al. · 2013

Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.

Whole body exposure to 2.4 GHz WIFI signals: Effects on cognitive impairment in adult triple transgenic mouse models of Alzheimer's disease (3xTg-AD)

Banaceur S, Banasr S, Sakly M, Abdelmelek H · 2013

Researchers studied the effects of 2.4 GHz radiofrequency signals on wildtype mice and triple transgenic mice bred to develop Alzheimer's-like cognitive impairment. Mice were exposed two hours per day during one month at a Specific Absorption Rate of 1.60 W/kg. The researchers reported that radiofrequency exposure improved cognitive behavior in the 3xTg-AD mice.

The effect of pulsed electromagnetic radiation from mobile phone on the levels of monoamine neurotransmitters in four different areas of rat brain

Aboul Ezz HS, Khadrawy YA, Ahmed NA, Radwan NM, El Bakry MM · 2013

Researchers investigated the effect of electromagnetic radiation on concentrations of dopamine, norepinephrine, and serotonin in the hippocampus, hypothalamus, midbrain, and medulla oblongata of adult rats. Adult rats were exposed daily to electromagnetic radiation at 1800 MHz, with a specific absorption rate of 0.843 W/kg and power density of 0.02 mW/cm2, modulated at 217 Hz. Measurements were taken after 1, 2, and 4 months of daily exposure, and also after stopping exposure for 1 month following 4 months of daily exposure. The exposure resulted in significant changes in dopamine, norepinephrine, and serotonin in all four brain areas studied.

Brain & Nervous SystemNo Effects Found

Repetitive exposure to a 7 Tesla static magnetic field of mice in utero does not cause alterations in basal emotional and cognitive behavior in adulthood

Unknown authors · 2012

Researchers conducted a comprehensive investigation of emotional and cognitive behavior in adult mice repeatedly exposed to a 7 Tesla static magnetic field in utero. Using well-validated tests, they did not observe any adverse behavioral alterations regarding emotional behavior as well as spatial and emotional learning. The study was motivated by increasing use of MRI in obstetrics and development of higher-performance systems with stronger fields requiring ongoing safety evaluation. Rodent studies provide an excellent opportunity to investigate acute and long-term effects of magnetic field exposure systematically.

Toxic effects of 50 Hz electromagnetic field on memory consolidation in male and female mice

Unknown authors · 2012

Researchers studied the effect of an 8 mT, 50 Hz electromagnetic field on memory consolidation in adult male and female mice. Mice were randomly assigned to six groups of ten each, with experimental groups exposed to the field for 4 hours after learning, sham-exposed groups, and control groups. Memory consolidation was assessed Twenty-four hours later using step-down latency in a passive avoidance task, and exposure significantly decreased memory function in both sexes.

Is there a relation between extremely low frequency magnetic field exposure, inflammation and neurodegenerative diseases? A review of in vivo and in vitro experimental evidence

Unknown authors · 2012

The review examined animal and in vitro studies of extremely low frequency magnetic fields to assess mechanistic support for a link to neurodegenerative diseases. The authors hypothesized that such exposure could promote inflammation and affect disease progression. Studies on neurodegenerative disease endpoints showed either no effect or positive effects on neuronal viability and differentiation.

Brain & Nervous System
Review
197 citations

Electromagnetic fields, oxidative stress, and neurodegeneration

Unknown authors · 2012

The review synthesizes the emerging evidence about this topic. It highlights wide data uncertainty that still characterizes the EMF effect on oxidative stress modulation. Both pro-oxidant and neuroprotective effects have been documented. Two decades of epidemiological studies consistently assessed an increased risk for childhood leukemia associated with extremely low frequency fields, leading the International Agency for Research on Cancer to classify them as Group 2B carcinogens in 2001.

Exposure system to study hypotheses of ELF and RF electromagnetic field interactions of mobile phones with the central nervous system

Murbach M et al · 2012

The system provides the same exposure of the lateral cerebral cortex at two different RF frequencies (900 and 2140 MHz) but with different exposure levels at subcortical structures. The RF modulation and ELF signal are generated by a freely programmable arbitrary signal generator enabling simulation of worst-case exposure scenarios from wireless devices. The maximum achievable RF exposure exceeds 60 W/kg peak spatial specific absorption rate averaged over 10 g of tissue.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects. This isn't a fringe concern or preliminary finding. This is the dominant scientific picture, and it deserves your attention. The documented effects span multiple systems within your nervous system.
The SYB Research Database includes 1,950 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
83% of the 1,950 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1621 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 17% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.