3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Estimation of relative exposure levels for cellular phone users using a neural network.

Kim SC, Nam KC, Kim DW. · 2006

Researchers developed a computer model to estimate how much radiofrequency radiation different cell phone users receive based on their usage patterns. The model considers factors like daily usage time, hands-free use, phone type, and the phone's specific absorption rate (SAR) to rank exposure risk on a 0-10 scale. This tool could help scientists better categorize study participants in future research investigating links between cell phone radiation and brain cancer.

The effect of increase in dielectric values on specific absorption rate (SAR) in eye and head tissues following 900, 1800 and 2450 MHz radio frequency (RF) exposure.

Keshvari J, Keshvari R, Lang S. · 2006

Researchers used computer modeling to examine how radiofrequency energy from cell phones is absorbed by children's heads compared to adults, accounting for the fact that children's tissues have higher water content. They tested common cell phone frequencies (900, 1800, and 2450 MHz) and found that even when tissue water content was increased by 5-20% to simulate children's physiology, energy absorption (SAR) varied by only about 5% on average. The study suggests that tissue composition differences between children and adults may have less impact on RF absorption than previously thought.

Neuropsychological sequelae of digital mobile phone exposure in humans.

Keetley V, Wood AW, Spong J, Stough C. · 2006

Researchers tested 120 people on cognitive tasks while exposed to cell phone radiation at maximum legal power levels. They found that phone radiation slowed down simple reaction times (how quickly people could respond to basic signals) but improved performance on complex memory tasks. This suggests cell phone radiation can alter brain function in measurable ways, though the effects varied depending on the type of mental task.

Driver distraction: The effects of concurrent in-vehicle tasks, road environment complexity and age on driving performance.

Horberry T, Anderson J, Regan MA, Triggs TJ, Brown J. · 2006

Researchers used driving simulators to study how using cell phones hands-free and operating entertainment systems affects driving performance across different age groups and road complexities. They found that both activities significantly impaired driving ability, increased reaction times to hazards, and made drivers feel more mentally overloaded. The entertainment system caused more problems than hands-free phone use, and these effects occurred regardless of driver age or whether roads were simple or complex.

Cancer & Tumors231 citations

Pooled analysis of two case-control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997-2003.

Hardell L, Carlberg M, Hansson Mild K. · 2006

Researchers analyzed phone use data from 905 brain cancer patients and 2,162 healthy controls to examine whether cellular and cordless phones increase brain tumor risk. They found that heavy phone users (more than 2,000 hours of lifetime use) had significantly higher rates of malignant brain tumors, with analog phones showing the highest risk at nearly 6 times normal rates. The risk was greatest when tumors developed on the same side of the head where people typically held their phone.

Cancer & Tumors158 citations

Pooled analysis of two case-control studies on the use of cellular and cordless telephones and the risk of benign brain tumours diagnosed during 1997-2003.

Hardell L, Carlberg M, Hansson Mild K. · 2006

Swedish researchers analyzed data from over 3,400 people to examine whether cell phone and cordless phone use increases the risk of benign brain tumors. They found that analog cell phone users had nearly triple the risk of developing acoustic neuroma (a tumor affecting hearing), while digital phones and cordless phones showed more modest increases in risk. The risk was highest among people who had used analog phones for more than 15 years.

Cancer & Tumors129 citations

Case-control study of the association between the use of cellular and cordless telephones and malignant brain tumors diagnosed during 2000-2003.

Hardell, L., Carlberg, M., Mild, K., 2005. · 2006

Swedish researchers studied 317 people with malignant brain tumors and compared their phone usage to 692 healthy controls. They found that people who used analog cell phones, digital cell phones, or cordless phones had roughly 2-3 times higher odds of developing brain tumors, with the risk increasing to 3-4 times higher for those who used phones for more than 10 years. The risk was strongest for high-grade astrocytoma, an aggressive type of brain cancer.

Pulsed radiofrequency applied to dorsal root ganglia causes a selective increase in ATF3 in small neurons.

Hamann W, Abou-Sherif S, Thompson S, Hall S. · 2006

Researchers applied pulsed radiofrequency energy to nerve areas in rats and found it triggered a stress response in small pain-sensing neurons, even at temperatures below what would cause obvious tissue damage. The treatment specifically affected the types of nerve cells that carry pain signals (C and A-delta fibers), suggesting radiofrequency can alter nerve function through non-thermal mechanisms. This challenges the assumption that RF energy is only harmful when it heats tissue enough to cause visible damage.

Mobile phone emissions and human brain excitability.

Ferreri F et al. · 2006

Researchers used brain stimulation techniques to measure how cell phone radiation affects brain activity in 15 men during 45-minute exposures. They found that GSM phone signals significantly altered brain excitability patterns, reducing the brain's natural inhibitory responses and enhancing facilitation in the exposed hemisphere compared to the unexposed side. This demonstrates that mobile phone emissions can measurably change how brain circuits function, even without causing any temperature increase.

Effect of pierced metallic objects on sar distributions at 900 MHz.

Fayos-Fernandez J et al. · 2006

Spanish researchers studied how metallic ear piercings affect radiation absorption when using cell phones at 900 MHz. They found that wearing metal objects near your ear increases peak SAR (specific absorption rate) values, meaning more electromagnetic energy gets absorbed by your head tissues. This suggests that common accessories like earrings could amplify your exposure to cell phone radiation.

Short-term effects of GSM mobiles phones on spectral components of the human electroencephalogram.

Faucon G, Le Bouquin Jeannes R, Maby E. · 2006

Researchers measured brain wave activity in 9 healthy people and 6 epileptic patients while they were exposed to GSM cell phone signals. The study found that cell phone radiation altered the brain's electrical patterns in both groups, decreasing energy in certain brain wave frequencies for healthy subjects and increasing it for epileptic patients. This demonstrates that even short-term exposure to cell phone radiation can measurably change how the brain functions electrically.

Effect of electromagnetic fields emitted by cellular phones on the latency of evoked electrodermal activity.

Esen F, Esen H · 2006

Turkish researchers examined how cell phone radiation affects the nervous system by measuring skin conductance responses, which reflect sympathetic nervous system activity. They found that exposure to cell phone electromagnetic fields delayed these neurological responses by about 200 milliseconds and disrupted normal brain hemisphere coordination. This suggests cell phone radiation can interfere with brain timing functions that are crucial for motor responses and reaction times.

Effects of radiofrequency radiation emitted by cellular telephones on the cognitive functions of humans.

Eliyahu I et al. · 2006

Israeli researchers exposed 36 healthy men to cell phone radiation at 890 MHz for two hours while they performed cognitive tasks designed to test different brain regions. They found that radiation exposure to the left side of the brain significantly slowed reaction times for left-hand responses, particularly during the second hour of exposure. This suggests that cell phone radiation can impair cognitive performance in the specific brain areas closest to the phone.

Electromagnetic absorption in the head of adults and children due to mobile phone operation close to the head.

de Salles AA, Bulla G, Rodriguez CE. · 2006

Researchers used computer simulations to compare how much radiofrequency radiation children's heads absorb from mobile phones compared to adults. They found that 10-year-old children absorb over 60% more radiation in their heads than adults when using the same phone. This happens because children have smaller heads, thinner skulls, and different tissue properties that allow deeper radiation penetration.

Occupational exposure to radio frequency/microwave radiation and the risk of brain tumors: Interphone Study Group, Germany.

Berg G et al. · 2006

German researchers studied nearly 1,500 workers exposed to radio frequency radiation in their jobs to see if they developed brain tumors more often than unexposed people. While they found no statistically significant increase in brain cancer risk, workers with the highest occupational RF exposure showed a 21% higher risk of glioma and 34% higher risk of meningioma compared to unexposed workers. The researchers noted that longer exposure duration showed a concerning trend toward increased risk that warrants further investigation.

Engrossed in conversation: The impact of cell phones on simulated driving performance.

Beede KE, Kass SJ. · 2006

Researchers tested 36 college students in driving simulators to see how hands-free cell phone conversations affected their driving ability. They found that talking on the phone significantly impaired performance in all four areas measured: traffic violations (like speeding), lane maintenance, attention lapses (like stopping at green lights), and reaction times. The study demonstrates that even hands-free phone calls create dangerous cognitive distractions while driving.

Mobile phone affects cerebral blood flow in humans.

Aalto S et al. · 2006

Finnish researchers used brain imaging to study how cell phones affect blood flow in the brain while 12 men performed memory tasks. They found that an active mobile phone decreased blood flow directly beneath the antenna in the temporal lobe while increasing it in the frontal brain region. This provides the first direct evidence that cell phone radiation can measurably alter brain physiology in humans.

Extremely low frequency magnetic field induces hyperalgesia in mice modulated by nitric oxide synthesis

Jeong JH, Kum C, Choi HJ, Park ES, Sohn UD. · 2006

Researchers exposed mice to 60 Hz magnetic fields from household electricity and found it increased their pain sensitivity. The magnetic fields triggered nitric oxide production in the brain and spinal cord, lowering pain thresholds. This suggests common electrical frequencies may directly affect pain processing.

.[Effect of 1.8 GHz radiofrequency electromagnetic fields on the expression of microtubule associated protein 2 in rat neurons]

Zhao R, Zhang SZ, Yao GD, Lu DQ, Jiang H, Xu ZP · 2006

Researchers exposed newborn rat brain cells to 1.8 GHz radiofrequency radiation (similar to cell phone frequencies) at 2 watts per kilogram for 24 hours and found that 34 out of 1,200 genes changed their expression levels. Most notably, a gene called MAP2, which helps maintain the structural framework of brain cells, became significantly more active after radiation exposure.

Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons.

Xu S, Ning W, Xu Z, Zhou S, Chiang H, Luo J. · 2006

Researchers exposed rat brain cells to 1800-MHz cell phone radiation (the same frequency used by GSM phones) for 15 minutes daily over 8 days. They found that this exposure weakened the electrical connections between brain cells in the hippocampus, the brain region crucial for memory and learning. The radiation reduced the strength of signals that brain cells use to communicate with each other.

Psychophysiological tests and provocation of subjects with mobile phone related symptoms.

Wilen J, Johansson A, Kalezic N, Lyskov E, Sandstrom M. · 2006

Swedish researchers exposed 20 people who experience symptoms from mobile phones and 20 people without symptoms to 900 MHz cell phone radiation for 30 minutes at levels typical of phone use. While the radiation didn't cause immediate measurable changes in either group, the symptomatic individuals showed different nervous system patterns during cognitive tests, suggesting their autonomic nervous systems may function differently regardless of radiation exposure.

Protein Kinase C Activity in developing rat brain cells exposed to 2.45 GHz radiation

Paulraj R, Behari J · 2006

Researchers exposed developing rat brains to 2.45 GHz radiation (the same frequency as WiFi and microwaves) for 2 hours daily over 35 days. They found significant decreases in protein kinase C activity in the hippocampus, a brain region crucial for learning and memory, plus increased glial cells which can indicate brain inflammation. The study suggests that chronic microwave exposure during brain development may interfere with normal growth and cellular function.

Single strand DNA breaks in rat brain cells exposed to microwave radiation.

Paulraj R, Behari J · 2006

Researchers exposed developing rat brains to microwave radiation at frequencies commonly used in WiFi and radar systems (2.45 and 16.5 GHz) for 35 days. They found statistically significant DNA damage in brain cells, specifically single-strand breaks that can interfere with normal cellular function. This suggests that chronic exposure to low-level microwave radiation during brain development may cause genetic damage.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.