3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Brain & Nervous SystemNo Effects Found

UMTS Base Station-like Exposure, Well-Being, and Cognitive Performance.

Regel SJ et al. · 2006

Swiss researchers exposed 117 people (including those who claimed sensitivity to electromagnetic fields) to cell tower-like radio frequency signals for 45 minutes at different intensities. They found no meaningful effects on well-being or cognitive performance at any exposure level, even among people who believed they were sensitive to EMF. The study contradicted earlier Dutch research that suggested cell tower exposure could affect well-being.

DNA & Genetic DamageNo Effects Found

Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field.

Qutob SS et al. · 2006

Researchers exposed human brain cancer cells (glioblastoma) to 1.9 GHz radiofrequency radiation for 4 hours at power levels ranging from very low to quite high (0.1 to 10 W/kg SAR). They found no changes in gene expression at any exposure level, while heat treatment successfully triggered expected cellular stress responses. This suggests that RF fields at these levels don't alter how genes function in these particular brain cells.

Cancer & TumorsNo Effects Found

Mobile telephones and rates of brain cancer

Muscat JE, Hinsvark M, Malkin M · 2006

Researchers analyzed brain cancer rates in the United States from 1973 to 2002, comparing them to the dramatic rise in mobile phone use that began in 1984. Despite mobile phone subscriptions increasing exponentially during this period, rates of neuronal brain cancers remained unchanged. This suggests that mobile phone use does not increase the risk of these specific types of brain tumors.

Brain & Nervous SystemNo Effects Found

A study of the effects of cellular telephone microwave radiation on the auditory system in healthy men

Mora R, Crippa B, Mora F, Dellepiane M · 2006

Italian researchers tested whether cell phone radiation affects hearing by exposing 20 healthy men to phone signals (900-1,800 MHz) for 15-30 minutes while measuring their auditory responses. They found no changes in hearing function during or after exposure. This suggests short-term cell phone use doesn't immediately damage the auditory system.

Brain & Nervous SystemNo Effects Found

Proliferation and apoptosis in a neuroblastoma cell line exposed to 900 MHz modulated radiofrequency field

Merola P et al. · 2006

Italian researchers exposed neuroblastoma cells (a type of nerve cell) to 900 MHz radiofrequency radiation at levels higher than occupational safety limits for up to 72 hours. They found no significant changes in cell growth, death, or differentiation processes. This suggests that even at elevated exposure levels, this type of cell phone radiation may not directly damage these particular nerve cells in laboratory conditions.

Brain & Nervous SystemNo Effects Found

Scalp localization of human auditory cortical activity modified by GSM electromagnetic fields.

Maby E, Jeannes Rle B, Faucon G · 2006

French researchers studied how cell phone radiation affects brain activity by measuring electrical responses to sound in 9 healthy people and 6 epilepsy patients. They found that GSM phone signals altered the timing and strength of brain waves, with different effects in healthy people versus those with epilepsy. While the changes were measurable, the researchers couldn't determine if these brain activity modifications cause actual health problems.

Cellular EffectsNo Effects Found

Radiofrequency radiation does not induce stress response in human T-lymphocytes and rat primary astrocytes.

Lee JS, Huang TQ, Kim TH, Kim JY, Kim HJ, Pack JK, Seo JS. · 2006

Researchers exposed human immune cells and rat brain cells to cell phone-level radiofrequency radiation (1763 MHz) at power levels of 2 and 20 W/kg for up to one hour while carefully controlling temperature. They found no activation of cellular stress responses, including heat shock proteins and stress-signaling pathways that typically activate when cells are damaged. This suggests that RF radiation at these levels does not trigger the cellular alarm systems that respond to harmful stressors.

Cancer & TumorsNo Effects Found

Meta-analysis of mobile phone use and intracranial tumors.

Lahkola A, Tokola K, Auvinen A. · 2006

Researchers analyzed 12 studies involving 2,780 people with brain tumors to determine if mobile phone use increases cancer risk. They found no significant increase in brain tumor risk for people who used mobile phones for more than 5 years, with odds ratios (risk measures) hovering around 1.0 for all tumor types studied. This suggests that at least for the first 5-10 years of mobile phone use, the risk of developing brain tumors does not appear to increase substantially.

Brain & Nervous SystemNo Effects Found

Microwave exposure of neuronal cells in vitro: Study of apoptosis.

Joubert V et al. · 2006

French researchers exposed human brain cells to cell phone radiation at 900 MHz for 24 hours to see if it would trigger cell death (apoptosis). They tested two exposure levels - one mimicking typical phone use and another eight times higher. The study found no increase in brain cell death at either exposure level, suggesting that 24-hour exposure to cell phone radiation does not kill these particular brain cells.

Cancer & TumorsNo Effects Found

Mobile phone use and risk of glioma in adults: case-control study.

Hepworth SJ et al. · 2006

Researchers studied 966 glioma patients and 1,716 healthy controls to see if mobile phone use increases brain tumor risk. They found no overall increased risk of glioma from phone use, with an odds ratio of 0.94 (meaning slightly lower risk, though not statistically significant). However, they noted some curious findings about tumor location that they attributed to recall bias rather than real biological effects.

Brain & Nervous SystemNo Effects Found

The sensitivity of human event-related potentials and reaction time to mobile phone emitted electromagnetic fields.

Hamblin DL, Croft RJ, Wood AW, Stough C, Spong J. · 2006

Researchers exposed 120 people to mobile phone radiation for 30 minutes while measuring their brain activity and reaction times during cognitive tasks. They found no significant changes in brain function, reaction speed, or electrical brain patterns compared to fake exposure sessions. This contradicts some earlier studies that suggested cell phones might affect how quickly the brain processes information.

Brain & Nervous SystemNo Effects Found

Expression of the immediate early gene, c-fos, in fetal brain after whole of gestation exposure of pregnant mice to global system for mobile communication microwaves.

Finnie JW, Cai Z, Blumbergs PC, Manavis J, Kuchel TR. · 2006

Researchers exposed pregnant mice to 900 MHz cell phone radiation for one hour daily throughout pregnancy to see if it would stress developing fetal brains. They measured c-fos, a protein that appears when brain cells are under stress. The study found no difference in stress markers between exposed and unexposed fetal brains, suggesting this level of radiation didn't cause detectable neural stress during development.

Brain & Nervous SystemNo Effects Found

Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain.

Finnie JW, Blumbergs PC, Cai Z, Manavis J, Kuchel TR. · 2006

Researchers exposed pregnant mice to cell phone-like radiation (900 MHz) for one hour daily throughout pregnancy to see if it would damage the blood-brain barrier in developing fetal brains. The blood-brain barrier is a protective filter that prevents harmful substances from entering brain tissue. They found no damage to this protective barrier in any brain region examined, suggesting the radiation exposure did not compromise brain protection during development.

DNA & Genetic DamageNo Effects Found

Investigation of co-genotoxic effects of radiofrequency electromagnetic fields in vivo.

Verschaeve L et al. · 2006

Researchers exposed female rats to cell phone radiation (900 MHz) for 2 years while also giving them a known cancer-causing chemical in their drinking water to see if the radiation would make DNA damage worse. They found that the radiation alone didn't cause genetic damage, and it didn't increase the DNA damage caused by the chemical. This suggests that long-term exposure to cell phone-level radiation may not enhance the harmful effects of other toxins on our genetic material.

Brain & Nervous SystemNo Effects Found

Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease.

Túnez I et al. · 2006

Researchers tested whether transcranial magnetic stimulation (TMS) could protect brain cells from damage caused by a toxic chemical that mimics Huntington's disease in rats. They found that TMS prevented cell death and reduced harmful oxidative stress in the brain region most affected by the disease. This suggests magnetic field therapy might offer neuroprotective benefits for degenerative brain conditions.

The Effects of Pulsed 860 MHz Radiofrequency Radiation on the Promotion of Neurogenic Tumors in Rats.

Zook BC,Simmens SJ. · 2006

Researchers exposed 1,080 rats to pulsed 860 MHz radiofrequency radiation (similar to cell phone signals) for 6 hours daily to see if it would accelerate tumor development in animals already given a cancer-causing chemical. After examining over 1,200 brain and nervous system tumors, they found no evidence that RF exposure affected tumor incidence, growth rate, severity, or how quickly tumors appeared. This suggests that this particular RF signal did not act as a tumor promoter in this animal model.

Does evening exposure to mobile phone radiation affect subsequent melatonin production?

Wood A, Loughran S, Stough C · 2006

Researchers exposed 55 adults to mobile phone radiation for 30 minutes before bedtime to see if it affected melatonin production, the hormone that regulates sleep. While total nighttime melatonin levels remained unchanged, the study found that phone exposure significantly reduced melatonin production in the pre-bedtime period. This suggests that evening phone use may delay the natural onset of melatonin, potentially disrupting your body's preparation for sleep.

Cancer & Tumors112 citations

The effects of recall errors and of selection bias in epidemiologic studies of mobile phone use and cancer risk.

Vrijheid M, Deltour I, Krewski D, Sanchez M, Cardis E. · 2006

Researchers used computer simulations to examine how memory errors and study design flaws might affect cancer research on cell phone use. They found that when people can't accurately remember their past phone usage, studies may significantly underestimate the true cancer risk from mobile phones. This suggests that existing studies showing little or no cancer risk may be missing real health effects due to these research limitations.

Interphone Study Group. Validation of short term recall of mobile phone use for the Interphone study.

Vrijheid M et al. · 2006

Researchers tracked actual mobile phone use in 672 volunteers across 11 countries using operator records and software-modified phones, then compared this to what people remembered six months later. The study found that people's memories were moderately accurate but contained significant errors - light users underestimated their phone use while heavy users overestimated it. This memory bias weakens the ability of cancer studies to detect real health risks from mobile phone radiation.

Long-term and frequent cellular phone use and risk of acoustic neuroma.

Salahaldin AH, Bener A. · 2006

Researchers in Qatar examined all 13 cases of acoustic neuroma (a type of brain tumor) diagnosed over two years and found that most patients were heavy cell phone users, making calls 14 times daily for over 5 years. The country's acoustic neuroma rate of 17.2 cases per million people was higher than rates reported in other countries. This suggests a potential link between intensive cell phone use and this specific type of brain tumor.

Acute mobile phone effects on pre-attentive operation.

Papageorgiou CC et al. · 2006

Researchers exposed 19 healthy adults to 900 MHz mobile phone radiation while measuring their brain activity during a working memory test. The radiation significantly altered brain wave patterns called P50 components, which reflect how the brain processes information before conscious awareness. These changes suggest that mobile phone emissions can affect fundamental brain processing, even during brief exposures.

Effects of intensive and moderate cellular phone use on hearing function.

Oktay MF, Dasdag S · 2006

Researchers compared hearing function in three groups of men: heavy cell phone users (2 hours daily for 4 years), moderate users (10-20 minutes daily), and non-users. Heavy users showed measurably worse hearing thresholds at specific frequencies, particularly at 4000 Hz, while moderate users showed no difference from non-users. This suggests that intensive cell phone use may contribute to hearing loss over time.

Short-term effects of GSM mobiles phones on spectral components of the human electroencephalogram.

Maby E, Le Bouquin Jeannes R, Faucon G. · 2006

Researchers exposed 15 people (9 healthy subjects and 6 epilepsy patients) to GSM cell phone signals while measuring their brain activity with EEG electrodes. They found that cell phone radiation altered the brain's electrical patterns in both groups - healthy people showed decreased brain wave activity, while epilepsy patients showed increased activity. The changes occurred specifically in areas of the brain associated with visual processing and consciousness.

GSM radiation triggers seizures and increases cerebral c-Fos positivity in rats pretreated with subconvulsive doses of picrotoxin.

Lopez-Martin E et al. · 2006

Spanish researchers studied whether cell phone radiation could trigger seizures in rats that were already vulnerable to seizures (treated with a brain chemical called picrotoxin). When exposed to 900 MHz GSM radiation similar to mobile phones for 2 hours, these seizure-prone rats developed actual seizures and showed increased brain activity markers, while control rats without radiation exposure did not seize. This suggests cell phone radiation might worsen seizure risk in individuals who are already neurologically vulnerable.

Mobile phone effects on children's event-related oscillatory EEG during an auditory memory task.

Krause CM et al. · 2006

Finnish researchers studied how mobile phone radiation affects brain activity in 15 children (ages 10-14) while they performed memory tasks. When exposed to 902 MHz radiation from an active phone, the children showed measurable changes in their brain wave patterns during both memory encoding and recognition phases. This demonstrates that cell phone radiation can directly alter brain function in developing minds, even during short-term exposure.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.