Kurzeja E et al. · 2013
Researchers studied the potential relationship between static magnetic field exposure and the antioxidant system of fibroblasts cultured with fluoride ions. Three chambers with static magnetic fields of different intensities (0.4, 0.6, and 0.7 T) were used, and fluoride ions were added at a concentration of 0.12 mM. Static magnetic fields were found to reduce the oxidative stress caused by fluoride ions and to normalize the activities of antioxidant enzymes including superoxide dismutase, glutathione peroxidase, and catalase. The results also suggest that exposure to fluoride and a static magnetic field improves the tolerance of cells to the oxidative stress induced by fluoride ions.
van Nierop LE et al. · 2011
Researchers tested whether movement-induced time-varying magnetic fields within the static magnetic stray field of a 7 Tesla MRI scanner affected neurocognition. Using a double-blind randomised crossover design, 31 healthy volunteers were tested in a sham (0 T), low (0.5 T) and high (1.0 T) exposure condition, with standardised head movements made before every neurocognitive task to induce time-varying magnetic fields. Of six tested neurocognitive domains, attention and concentration were negatively affected, and visuospatial orientation was also affected after exposure.
van Nierop LE, Slottje P, van Zandvoort M, Kromhout H. · 2014
This double-blind randomized crossover study tested whether static magnetic fields alone, or combined with movement-induced time-varying magnetic fields, affected neurocognitive performance in 36 healthy volunteers. The exposure conditions consisted of 1.0 T static magnetic fields with or without 2.4 T/s time-varying magnetic fields induced by standardized head movements before each of the five neurocognitive tasks. Combined exposure significantly decreased verbal memory performance, changed visual acuity, and negatively affected attention and concentration with borderline significance, while static field exposure alone had no significant effects.
Zhao G et al. · 2011
The study examined cellular effects of a strong homogeneous static magnetic field in human-hamster hybrid (AL) cells, mitochondria-deficient cells, and double-strand break repair-deficient cells. ATP content was significantly decreased in AL cells exposed to 8.5 Tesla but not 1 or 4 T static magnetic field for either 3 or 5 hours. Reactive oxygen species levels were significantly increased by 8.5 T exposure, and concurrent treatment with the ROS inhibitor DMSO dramatically suppressed the ATP content in exposed AL cells. Mutation frequency and cell cycle distribution were not significantly affected by 8.5 T exposure for 3 hours.
Pandir D, Sahingoz R · 2014
Researchers exposed Mediterranean flour moth (Ephestia kuehniella) larvae to a 1.4-Tesla magnetic field at 50 Hz for time periods ranging from 3 to 72 hours. DNA damage, measured by the comet assay, was significantly larger than in the control group at increasing exposure times. Antioxidant enzyme activities (SOD, CAT, GPx, and GST) decreased and the lipid peroxidation marker MDA increased in exposed larvae compared to controls.
Sirmatel O, Sert C, Sirmatel F, Selek S, Yokus B · 2007
Researchers investigated the effects of a 1.5 T static magnetic field, produced by an MRI apparatus, on oxidative stress markers in 33 male volunteers. Total antioxidant capacity showed a significant increase after exposure compared to before exposure (p < 0.05). Oxidative stress index and total oxidant status showed a significant decrease after exposure compared to before exposure (p < 0.01 for each). The researchers concluded that the 1.5 T static magnetic field produced a positive effect of decreasing oxidative stress in men following short-term exposure.
Sirmatel O, Sert C, Tümer C, Oztürk A, Bilgin M, Ziylan Z · 2007
Researchers measured nitric oxide production in 33 healthy young male volunteers aged 18 to 26 years old immediately after a 30-minute exposure to a 1.5 T magnetic field. A control group of 30 healthy male volunteers aged 19 to 26 years old was not exposed to the magnetic field, and their nitric oxide levels were also measured. Total nitrite concentration in post-exposure samples was found to be higher than in pre-exposure samples (P < .05).
D. Melville, F. Paul, S. Roath · 1975
Approximately 70% of red cells were retained until the field was turned off, with no evidence of immediate cell destruction. Scanning electron microscopy revealed slight surface abnormalities on a small proportion of filtered cells.
Lee JW, Kim MS, Kim YJ, Choi YJ, Lee Y, Chung HW. · 2011
Researchers investigated the genotoxic potential of 3 T clinical MRI scans in cultured human lymphocytes by exposing them to electromagnetic fields from a clinical brain protocol for 22, 45, 67, and 89 minutes. They observed a significant increase in single-strand DNA breaks after exposure. Micronuclei and chromosome aberration frequencies increased in a time-dependent manner.
Volkow ND et al. · 2010
Researchers measured brain glucose metabolism in fifteen healthy subjects inside a 4 T magnet, comparing conditions with and without echo-planar imaging (EPI) gradient pulses. Relative metabolism was lower in areas at the poles of the brain when the EPI pulses were on compared to when they were off. The size of the metabolic decreases was significantly correlated with the estimated strength of the electric field (r = 0.68, p < 0.0001), such that a stronger field was associated with larger decreases. No differences were detected between the ON and OFF conditions for mood ratings or for absolute whole-brain metabolism.
Mineta M et al. · 1999
Researchers exposed Salmonella typhimurium tester strains to a 6.3 Tesla magnetic field with RF radiation for up to 60 minutes. They used TA98 and TA7001-7006 mixed strains to detect frameshift and point mutations. The rates of revertant mutation were not statistically significant in either strain.