3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
Research Guide

Is 5G Safe? What the Research Actually Shows

Based on 574 peer-reviewed studies

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5G technology has generated significant public concern about health effects. The topic has also attracted misinformation, making it difficult for people to understand what scientific research actually shows about 5G safety.

5G operates across different frequency bands—some similar to existing 4G networks, others using higher frequencies (millimeter waves) that are relatively new for widespread consumer exposure. This page focuses on what peer-reviewed research says about radiofrequency radiation at 5G frequencies.

We present the scientific evidence objectively, including both studies that raise concerns and those that find no effects, so you can make informed judgments based on actual research.

Key Research Findings

  • Limited research exists specifically on 5G millimeter wave frequencies
  • Lower-band 5G uses frequencies similar to well-studied 4G/LTE
  • Swedish 2025 report: 'need for more research' on higher 5G bands

Related Studies (574)

Apoptosis is Induced by Radiofrequency Fields through the Caspase-Independent Mitochondrial Pathway in Cortical Neurons

Joubert, V., Bourthoumieu, S., Leveque, P. and Yardin, C. · 2008

Researchers exposed rat brain cells to cell phone-level radiofrequency radiation (900 MHz at 2 W/kg SAR) for 24 hours and found it triggered programmed cell death through a specific pathway involving mitochondria. The cell death occurred even when accounting for the slight heating effect of the radiation. This suggests that RF radiation can damage brain cells through non-thermal mechanisms at exposure levels similar to what cell phones produce.

Effect of 1.8 GHz radiofrequency electromagnetic fields on gene expression of rat neurons

Zhang SZ, Yao GD, Lu DQ, Chiang H, Xu ZP. · 2008

Chinese researchers exposed rat brain neurons to 1.8 GHz radiofrequency radiation (the same frequency used in cell phones) at 2 W/kg for up to 24 hours. They found that 34 genes changed their expression patterns, including genes involved in brain cell structure and signaling. The changes were more pronounced with intermittent exposure than continuous exposure, suggesting that the pattern of EMF exposure matters for biological effects.

Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells.

Yao K, Wu W, Wang K, Ni S, Ye P, Yu Y, Ye J, Sun L. · 2008

Researchers exposed human eye lens cells to 1.8 GHz radiofrequency radiation (the frequency used by GSM cell phones) at power levels of 1-4 watts per kilogram for 2 hours. They found that higher exposure levels caused DNA damage and increased harmful molecules called reactive oxygen species in the cells. Interestingly, when they added electromagnetic 'noise' to the radiation, it prevented these cellular damage effects.

Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes.

Schwarz C et al. · 2008

German researchers exposed human cells to cell phone radiation (UMTS, 1,950 MHz) at levels well below safety limits to test for DNA damage. They found that skin cells (fibroblasts) showed significant genetic damage at extremely low exposure levels - as little as 0.05 W/kg, which is 40 times lower than the current safety limit. However, immune cells (lymphocytes) showed no damage, suggesting different cell types respond differently to radiofrequency radiation.

Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours.

Mazor R et al. · 2008

Researchers exposed human blood cells to 800 MHz radiofrequency radiation (similar to cell phone frequencies) for 72 hours at levels close to current safety limits. They found significant increases in chromosome abnormalities called aneuploidy, where cells had the wrong number of chromosomes. This type of genetic damage can contribute to cancer development and other health problems.

DNA & Genetic DamageNo Effects Found101 citations

Genotoxic effects of exposure to radiofrequencyelectromagnetic fields (RF-EMF) in cultured mammalian cells are not independently reproducible.

Speit G, Schütz P, Hoffmann H. · 2007

German researchers attempted to replicate the controversial REFLEX study findings that showed cell phone radiation (1800 MHz) could damage DNA in human cells. Using identical equipment, cells, and exposure conditions, they found no DNA damage whatsoever. This directly contradicted the original REFLEX results that had suggested radiofrequency radiation at levels similar to cell phones could be genotoxic (DNA-damaging).

Cellular EffectsNo Effects Found

In Vitro Study of the Stress Response of Human Skin Cells to GSM-1800 Mobile Phone Signals Compared to UVB Radiation and Heat Shock.

Sanchez et al. · 2007

French researchers exposed human skin cells to GSM cell phone signals at the maximum allowed exposure level for 48 hours, looking for signs of cellular stress like those caused by heat or UV radiation. They found no evidence that the radiofrequency radiation caused stress responses or cell death, unlike the positive control treatments that clearly damaged cells. This suggests that cell phone radiation at current safety limits may not directly harm skin cells in laboratory conditions.

Reproductive HealthNo Effects Found

Effects of Subchronic Exposure to Radio Frequency From a Conventional Cellular Telephone on Testicular Function in Adult Rats.

Ribeiro EP, Rhoden EL, Horn MM, Rhoden C, Lima LP, Toniolo L · 2007

Researchers exposed adult rats to cell phone radiation (1,835-1,850 MHz) for one hour daily over 11 weeks to test effects on reproductive function. They found no changes in testosterone levels, sperm count, testicular weight, or tissue damage compared to unexposed rats. This study suggests that typical cell phone radiation exposure may not harm male fertility in the short term.

Brain & Nervous SystemNo Effects Found

Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba(2+) currents through voltage-gated calcium channels in rat cortical neurons.

Platano D et al. · 2007

Italian researchers exposed rat brain cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) for short periods to see if it affected calcium channels, which are crucial for nerve cell communication. They found no changes in how calcium moved through these channels, even at radiation levels of 2 W/kg. This suggests that brief cell phone-level exposures may not immediately disrupt this particular aspect of brain cell function.

Brain & Nervous SystemNo Effects Found

No apoptosis is induced in rat cortical neurons exposed to GSM phone fields.

Joubert V, Leveque P, Cueille M, Bourthoumieu S, Yardin C. · 2007

French researchers exposed rat brain neurons to cell phone radiation (900 MHz GSM) for 24 hours at levels similar to phone use (0.25 W/kg SAR) to see if it would cause cell death (apoptosis). Using three different testing methods, they found no increase in neuron death compared to unexposed control cells. This suggests that short-term cell phone radiation exposure may not directly kill brain cells under these laboratory conditions.

Cellular EffectsNo Effects Found

Mobile phone base station-emitted radiation does not induce phosphorylation of Hsp27.

Hirose H et al. · 2007

Japanese researchers exposed human brain and lung cells to radiofrequency radiation at levels similar to cell tower emissions (2.1 GHz) for up to 48 hours. They found no changes in heat shock proteins (cellular stress markers that increase when cells are damaged) even at exposure levels 10 times higher than public safety limits. This suggests that cell tower-level RF radiation does not trigger detectable cellular stress responses in laboratory conditions.

Cellular EffectsNo Effects Found

Evaluating the biological effects of intermittent 1.9 GHz pulse-modulated radiofrequency fields in a series of human-derived cell lines.

Chauhan V et al. · 2007

Canadian government researchers exposed three types of human cells to 1.9 GHz radiofrequency radiation (similar to cell phone signals) for 6 hours at power levels up to 10 W/kg. They measured multiple indicators of cellular stress including cell death, DNA damage, immune responses, and cell cycle disruption. The study found no detectable biological effects from the RF exposure at any power level tested.

DNA & Genetic DamageNo Effects Found

Analysis of gene expression in two human-derived cell lines exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field.

Chauhan V et al. · 2007

Canadian researchers exposed two types of human cells to 1.9 GHz radiofrequency radiation (similar to cell phone signals) for up to 24 hours at power levels ranging from very low to high. They found no changes in gene expression - meaning the RF exposure didn't turn genes on or off differently than unexposed cells. However, when they heated the same cells to 43°C (109°F) for comparison, multiple heat-shock genes activated as expected.

DNA & Genetic DamageNo Effects Found

Genotoxic effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in cultured mammalian cells are not independently reproducible.

Speit G, Schütz P, Hoffmann H. · 2007

German researchers exposed mammalian cells to radiofrequency radiation at cell phone levels (1800 MHz, SAR 2 W/kg) to test whether RF exposure causes DNA damage. Using two different cell lines and multiple DNA damage tests, they found no genetic damage from the radiation exposure. This study contradicted earlier findings from the REFLEX project that had reported DNA damage from similar RF exposures.

Brain & Nervous SystemNo Effects Found

Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba 2+ currents through voltage-gated calcium channels in rat cortical neurons.

Platano D et al. · 2007

Italian researchers exposed rat brain cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) to see if it affected calcium channels, which are crucial for brain cell communication. After exposing the cells to radiation at 2 W/kg for short periods, they found no changes in how calcium moved through these channels. This suggests that brief exposure to cell phone-level radiation may not immediately disrupt this particular aspect of brain cell function.

Brain & Nervous SystemNo Effects Found

No apoptosis is induced in rat cortical neurons exposed to GSM phone fields.

Joubert V, Leveque P, Cueille M, Bourthoumieu S, Yardin C. · 2007

French researchers exposed rat brain neurons to cell phone radiation (900 MHz GSM) for 24 hours at levels similar to phone use, then tested whether the radiation caused brain cells to die through a process called apoptosis. Using three different measurement methods, they found no increase in cell death compared to unexposed neurons. This suggests that brief cell phone radiation exposure may not directly damage brain cells in the way some scientists have theorized.

Cellular EffectsNo Effects Found

Mobile phone base station‐emitted radiation does not induce phosphorylation of Hsp27

Hirose H et al. · 2007

Researchers exposed human brain and lung cells to cell phone tower radiation at levels up to 10 times higher than public safety limits to test whether it triggers heat shock proteins (cellular stress markers). After continuous exposure for up to 48 hours, they found no increase in these stress proteins compared to unexposed cells. This suggests that cell phone tower radiation at these levels doesn't cause detectable cellular stress responses.

Comparison of bioactivity between GSM 900 MHz and DCS 1800 MHz mobile telephony radiation.

Panagopoulos DJ et al. · 2007

Researchers exposed fruit flies to two different types of cell phone radiation - GSM 900 MHz (used in older phones) and DCS 1800 MHz (used in newer phones) - to compare their biological effects. Both types of radiation significantly reduced the flies' ability to reproduce, but the lower frequency GSM 900 MHz radiation proved more harmful than the higher frequency DCS 1800 MHz radiation. The study suggests that radiation intensity matters more than the specific frequency when it comes to biological damage.

Denaturation of hen egg white lysozyme in electromagnetic fields: A molecular dynamics study.

English NJ, Mooney DA. · 2007

Researchers used computer simulations to study how electromagnetic fields affect lysozyme, a protein found in egg whites and human tears. They found that EMF exposure caused the protein to unfold and lose its normal structure, even without heating. This protein damage occurred at field strengths comparable to what causes heat damage at temperatures of 400-500 K (260-440°F).

Anticancer effects on leiomyosarcoma-bearing Wistar rats after electromagnetic radiation of resonant radiofrequencies.

Avdikos A et al. · 2007

Greek researchers exposed cancer cells to specific radiofrequencies (10-120 kHz) and found these treated cells formed tumors that grew more slowly and caused less death in rats. When rats with existing tumors were exposed to the same resonant frequencies for 5 hours daily, one-third of their tumors completely disappeared. This suggests certain electromagnetic frequencies might have therapeutic rather than harmful effects on cancer.

900 MHz radiofrequency-induced histopathologic changes and oxidative stress in rat endometrium: protection by vitamins E and C.

Guney M, Ozguner F, Oral B, Karahan N, Mungan T. · 2007

Researchers exposed female rats to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 30 minutes daily over 30 days and examined the effects on endometrial tissue (the lining of the uterus). The radiation caused significant oxidative damage and tissue inflammation in the endometrium, but these harmful effects were largely prevented when the rats were given vitamins E and C. This suggests that cell phone-frequency radiation may damage reproductive tissues through oxidative stress, but antioxidant protection could help mitigate these effects.

Effect of whole-body exposure to high-frequency electromagnetic field on the brain cortical and hippocampal activity in mouse experimental model

Barcal J, Vozeh F · 2007

Researchers exposed mice to 900 MHz electromagnetic radiation (the same frequency used by cell phones) and directly measured brain activity in two key regions: the cortex and hippocampus. They found that this radiation altered normal brain wave patterns, shifting cortical activity to lower frequencies while increasing higher frequencies in the hippocampus. These changes occurred even though the mice received lower radiation doses than humans typically get when using cell phones.

Formation of reactive oxygen species in L929 cells after exposure to 900 MHz RF radiation with and without Co-exposure to 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone.

Zeni O et al. · 2007

Researchers exposed mouse cells to 900 MHz cell phone radiation for up to 30 minutes to test whether it creates harmful reactive oxygen species that damage cells. The study found no increase in these damaging molecules from RF exposure alone, suggesting this frequency may not cause oxidative cellular stress.

Formation of Reactive Oxygen Species in L929 Cells after Exposure to 900 MHz RF Radiation with and without Co-exposure to 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone.

Zeni et al. · 2007

Researchers exposed mouse cells to 900 MHz cell phone radiation for up to 30 minutes to test whether it creates harmful molecules called reactive oxygen species. The radiation did not increase these damaging molecules at any exposure level tested, suggesting no immediate cellular harm.

Further Reading

For a comprehensive exploration of EMF health effects and practical protection strategies, explore these books by R Blank and Dr. Martin Blank.