3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
Research Guide

Is 5G Safe? What the Research Actually Shows

Based on 574 peer-reviewed studies

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5G technology has generated significant public concern about health effects. The topic has also attracted misinformation, making it difficult for people to understand what scientific research actually shows about 5G safety.

5G operates across different frequency bands—some similar to existing 4G networks, others using higher frequencies (millimeter waves) that are relatively new for widespread consumer exposure. This page focuses on what peer-reviewed research says about radiofrequency radiation at 5G frequencies.

We present the scientific evidence objectively, including both studies that raise concerns and those that find no effects, so you can make informed judgments based on actual research.

Key Research Findings

  • Limited research exists specifically on 5G millimeter wave frequencies
  • Lower-band 5G uses frequencies similar to well-studied 4G/LTE
  • Swedish 2025 report: 'need for more research' on higher 5G bands

Related Studies (574)

2-Methoxyethanol metabolism, embryonic distribution, and macromolecular adduct formation in the rat: the effect of radiofrequency radiation-induced hyperthermia.

Cheever KL et al. · 2001

Researchers exposed pregnant rats to radiofrequency radiation (10 MHz) combined with a toxic industrial solvent to understand why this combination causes more birth defects than either exposure alone. They found that RF radiation slowed the body's ability to clear the toxic chemical from the system over 24-48 hours, though it didn't change how the chemical was processed or distributed to developing embryos. This suggests RF radiation may enhance chemical toxicity by interfering with the body's natural detoxification processes.

Effects of acute exposure to the radiofrequency fields of cellular phones on plasma lipid peroxide and antioxidase activities in human erythrocytes.

Moustafa YM, Moustafa RM, Belacy A, Abou-El-Ela SH, Ali FM. · 2001

Researchers tested 12 healthy men who carried cell phones in standby mode in their pockets for up to 4 hours. They found that even this minimal exposure significantly increased markers of cellular damage (lipid peroxides) and reduced the body's natural antioxidant defenses. This suggests that cell phones can trigger oxidative stress - the same biological process linked to aging and disease - even when not actively being used.

Effects of radiofrequency exposure on the GABAergic system in the rat cerebellum: clues from semi-quantitative immunohistochemistry

Mausset A, de Seze R, Montpeyroux F, Privat A · 2001

French researchers exposed rats to 900 MHz radiofrequency radiation (the same frequency used by many cell phones) and measured changes in GABA, a crucial brain chemical that helps regulate nerve activity. They found that RF exposure reduced GABA levels in the cerebellum, the brain region responsible for movement and coordination. This suggests that cell phone radiation may disrupt normal brain chemistry at the cellular level.

[Effect of extremely high frequency electromagnetic radiation of low intensity on parameters of humoral immunity in healthy mice.]

Lushnikov KV, Gapeev AB, Sadovnikov VB, Cheremis NK. · 2001

Russian researchers exposed mice to 42 GHz radiation (millimeter waves like those in 5G) at low power levels. After 20 days of daily exposure, immune organs shrank significantly - the thymus by 17.5% and spleen by 14.5%, suggesting prolonged millimeter wave exposure may weaken immune system function.

Effect of Exposure to 900 MHz Radiofrequency Radiation on Intrachromosomal Recombination in pKZ1 Mice.

Sykes PJ, McCallum BD, Bangay MJ, Hooker AM, Morley AA. · 2001

Researchers exposed mice to pulsed 900 MHz cell phone radiation for 30 minutes daily over different time periods to study effects on DNA recombination (the natural process where chromosomes exchange genetic material). After 25 days of exposure at 4 W/kg, they found a significant reduction in normal DNA recombination events in spleen tissue. This suggests that RF radiation can disrupt the cellular mechanisms that help repair DNA damage.

DNA & Genetic DamageNo Effects Found

Cytogenetic investigations on microwavesemitted by a 455.7 MHz car phone

Maes A, Collier M, Verschaeve L · 2000

Belgian researchers exposed human immune cells (lymphocytes) to radiation from a 455.7 MHz car phone at high intensity levels (6.5 W/kg SAR) to see if it would cause genetic damage or make the cells more vulnerable to other cancer-causing agents. They found no evidence that the phone radiation caused chromosome damage on its own, nor did it increase the harmful effects when combined with known mutagens like chemicals or X-rays.

DNA & Genetic DamageNo Effects Found

Primary DNA Damage in Human Blood Lymphocytes Exposed In Vitro to 2450 MHz Radiofrequency Radiation.

Vijayalaxmi, Leal BZ, Szilagyi M, Prihoda TJ, Meltz ML · 2000

Researchers exposed human blood cells to microwave radiation at 2450 MHz (the same frequency used in microwave ovens and some WiFi devices) for 2 hours to see if it would damage DNA. They found no evidence of DNA breaks or damage in the cells, even when they checked again 4 hours later to see if the cells could repair any potential damage. This suggests that this specific type and level of radiofrequency exposure may not cause immediate DNA harm.

Electromagnetic fields (1.8 GHz) increase the permeability to sucrose of the blood-brain barrier in vitro.

Schirmacher A et al. · 2000

Researchers exposed a laboratory model of the blood-brain barrier (the protective membrane that shields your brain from toxins in your blood) to cell phone radiation at 1.8 GHz. They found that this exposure significantly increased the barrier's permeability, allowing substances like sucrose to pass through more easily. This suggests that cell phone radiation may compromise the brain's natural protection system, potentially allowing harmful substances to reach brain tissue.

The simulation of the cooperative effect of development in a culture of early mouse embryos after irradiation with electromagnetic waves in the millimeter range.

Mezhevikina LM, Khramov RN, Lepikhov KA · 2000

Researchers exposed two-cell mouse embryos to millimeter wave electromagnetic radiation for 30 minutes and found the exposure stimulated the embryos to develop on their own without needing growth factors or serum. The treated embryos were able to reach the blastocyst stage (an important early developmental milestone) in laboratory culture conditions. This suggests millimeter waves can activate metabolic processes that control early embryonic development.

[Modeling of the effect of modulated electromagnetic radiation on animal cells].

Gapeev AB, Chemeris NK · 2000

Russian researchers created a mathematical model to understand how electromagnetic radiation affects calcium levels inside immune cells called neutrophils. They found that when the radiation frequency matched the cell's natural calcium signaling rhythm (around 1 Hz), it could increase calcium levels by more than 50%. This suggests that EMF exposure might disrupt normal cell function by interfering with the calcium signals that cells use to communicate and respond to their environment.

Combined effects of traffic and electromagnetic fields on the immune system of fertile atopic women.

Del Signore A, Boscolo P, Kouri S, Di Martino G, Giuliano G · 2000

Researchers studied how electromagnetic fields affect the immune systems of women with allergies compared to those without, all living in areas with traffic pollution. They found that women with allergies who were also exposed to electromagnetic fields had weakened immune responses, including reduced natural killer cell activity and higher allergy markers. This suggests that people with existing allergies may be more vulnerable to electromagnetic field exposure.

Zeeman-Stark modeling of the RF EMF interaction with ligand binding.

Chiabrera A, Bianco B, Moggia E, Kaufman JJ, · 2000

Researchers developed a quantum physics model to explain how radiofrequency electromagnetic fields might interfere with the way molecules bind to proteins inside cells. Their mathematical model suggests that RF radiation could disrupt these fundamental cellular processes when the energy of the electromagnetic waves matches specific protein structures. The findings indicate that current safety standards may need revision to account for these subtle but potentially significant biological interactions.

Ets1 oncogene induction by ELF-modulated 50 MHz radiofrequency electromagnetic field

Romano-Spica V, Mucci N, Ursini CL, Ianni A, Bhat NK · 2000

Italian researchers exposed blood and reproductive cells to radiofrequency radiation (50 MHz) combined with extremely low frequency modulation (16 Hz) to study effects on gene activity. They found that this specific combination activated the ets1 gene, which is associated with cancer development, but only when the low-frequency modulation was present. This suggests that the pulsing or modulation of RF signals may be more biologically active than continuous exposure.

CardiovascularNo Effects Found

Membrane potential and currents of isolated heart muscle cells exposed to pulsed radio frequency fields.

Linz et al. · 1999

German researchers exposed isolated heart muscle cells from guinea pigs and rats to cell phone frequencies (900 MHz and 1800 MHz) to see if radio waves affected the cells' electrical activity. They found no significant changes to the heart cells' membrane potential, action potentials, or calcium and potassium currents even at exposure levels up to 880 mW/kg. The study suggests that cell phone radiation at these levels does not directly disrupt the basic electrical functions of heart muscle cells.

DNA & Genetic DamageNo Effects Found

Proto-oncogene mRNA levels and activities of multiple transcription factors in C3H 10T 1/2 murine embryonic fibroblasts exposed to 835.62 and 847.74 MHz cellular phone communication frequency radiation.

Goswami PC et al. · 1999

Researchers exposed mouse cells to cellular phone radiation at 835 MHz and 847 MHz (similar to early cell phones) to see if it triggered stress responses. While most stress indicators showed no change, one specific gene called Fos increased by 40-100% in exposed cells. This suggests cell phone radiation can alter gene activity even when it doesn't cause obvious cellular stress.

Cellular Effects186 citations

The effects of radiofrequency fields on cell proliferation are non-thermal.

Velizarov, S, Raskmark, P, Kwee, S, · 1999

Researchers exposed cells to 960 MHz radiofrequency radiation (similar to cell phone signals) at different temperatures to test whether heat alone causes biological effects. They found that RF radiation altered cell growth patterns at both higher and lower temperatures, proving that the effects weren't simply due to heating. This challenges the mainstream assumption that only thermal effects from wireless radiation can impact living cells.

IRIDIUM exposure increases c-fos expression in the mouse brain only at levels which likely result in tissue heating.

Morrissey JJ et al. · 1999

Researchers exposed mice to 1.6-GHz radiofrequency signals (similar to satellite phone frequencies) for one hour to see if it affected brain activity. They found that brain changes only occurred at exposure levels 6-30 times higher than current safety limits for cell phones, and these changes appeared to be caused by tissue heating rather than direct effects from the radiation itself.

[Resonance interactions of surface charged lipid vesicles with the microwave electromagnetic field].

Krasil'nikov PM · 1999

Russian researchers studied how microwave electromagnetic fields interact with cell membranes at the molecular level. They found that these fields can create resonant effects in the charged particles on membrane surfaces, potentially causing cells to cluster together in unusual patterns. This suggests that microwave radiation may directly alter fundamental cellular processes through electromagnetic interactions with membrane structures.

Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain.

Paul Raj R, Behari J, Rao AR · 1999

Researchers exposed young rats to radiofrequency radiation at cell phone-like levels for 35 days and found significant changes in brain chemistry, including increased calcium movement and enzyme activity. These cellular changes in developing brains suggest RF exposure during growth may disrupt normal brain function.

[Effect of millimeter waves on the early development of the mouse and sea urchin embryo].

Galat VV et al. · 1999

Russian researchers exposed mouse and sea urchin embryos to millimeter wave radiation (54-78 GHz) at very low power levels for 30 minutes during early development. They found that exposed mouse embryos developed faster and more successfully reached the blastocyst stage compared to unexposed controls. The radiation appeared to strengthen embryos against environmental stress, suggesting these frequencies may have biological effects even at non-thermal levels.

Microwave irradiation influences on the state of human cell nuclei.

Shckorbatov YG et al. · 1998

Ukrainian researchers exposed human cheek cells to millimeter wave radiation at 42.2 GHz and found it altered the cells' nuclei in two key ways: it reduced the electrical charge of the cell nucleus and increased chromatin condensation (DNA packaging became tighter). The effects varied based on radiation dose and individual differences between cell donors, suggesting that millimeter wave exposure can directly impact cellular structures at the genetic level.

Cellular Effects103 citations

Transgenic nematodes as biomonitors of microwave-induced stress.

Daniells et al. · 1998

Scientists exposed genetically modified nematode worms to microwave radiation at 750 and 300 MHz frequencies and measured their cellular stress responses through a special gene that acts like a biological alarm system. The worms showed significant stress responses to the microwave exposure, with the strongest effects occurring closest to the radiation source and weaker responses at lower power levels. This suggests the radiation was causing cellular damage similar to what toxic metals produce, rather than simple heating effects.

Interaction of low level modulated RF radiation with Na+¯K+-ATPase.

Behari J, Kunjilwar KK, and Pyne S · 1998

Researchers exposed developing rats to radiofrequency radiation similar to what cell phones emit and found it significantly increased activity of a critical brain enzyme called Na+-K+-ATPase by 15-20%. This enzyme is essential for nerve cell function and brain development. The findings suggest that RF radiation can alter fundamental brain chemistry in developing animals, raising concerns about potential effects on brain development in children.

Further Reading

For a comprehensive exploration of EMF health effects and practical protection strategies, explore these books by R Blank and Dr. Martin Blank.