3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
Research Guide

Is 5G Safe? What the Research Actually Shows

Based on 574 peer-reviewed studies

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5G technology has generated significant public concern about health effects. The topic has also attracted misinformation, making it difficult for people to understand what scientific research actually shows about 5G safety.

5G operates across different frequency bands—some similar to existing 4G networks, others using higher frequencies (millimeter waves) that are relatively new for widespread consumer exposure. This page focuses on what peer-reviewed research says about radiofrequency radiation at 5G frequencies.

We present the scientific evidence objectively, including both studies that raise concerns and those that find no effects, so you can make informed judgments based on actual research.

Key Research Findings

  • Limited research exists specifically on 5G millimeter wave frequencies
  • Lower-band 5G uses frequencies similar to well-studied 4G/LTE
  • Swedish 2025 report: 'need for more research' on higher 5G bands

Related Studies (574)

In-vitro exposure of neuronal networks to the GSM-1800 signal.

Moretti D et al. · 2013

French researchers exposed lab-grown brain cells to cell phone radiation at 1800 MHz (the frequency used by GSM cell phones) for just 3 minutes. They found that the radiation caused a 30% decrease in the neurons' electrical activity - essentially making the brain cells less active. This effect was reversible, meaning the neurons returned to normal activity levels after the exposure ended.

DNA & Genetic DamageNo Effects Found

Effect of mobile phones on micronucleus frequency in human exfoliated oral mucosal cells.

Ros-Llor I et al. · 2012

Researchers examined DNA damage in mouth cells from 50 mobile phone users by comparing cells from the side of the face where they held their phone versus the opposite side. They found no differences in genetic damage markers (called micronuclei) between the phone side and non-phone side, regardless of how long people had been using mobile phones. This suggests that typical mobile phone use may not cause detectable DNA damage in oral tissues.

Oxidative StressNo Effects Found

Biological indicators in response to radiofrequency/microwave exposure

Marjanović AM, Pavičić I, Trošić I · 2012

This Croatian research team reviewed the current scientific understanding of how radiofrequency and microwave radiation (from devices like cell phones and WiFi) might affect living cells. They focused on reactive oxygen species (ROS) - molecules that can damage cells when produced in excess - as a potential mechanism for non-thermal biological effects. The paper calls for more laboratory research to better understand these mechanisms and support public health risk assessment.

Immune SystemNo Effects Found

Prenatal exposure to radiofrequencies: Effects of WiFi signals on thymocyte development and peripheral T cell compartment in an animal model.

Laudisi F et al. · 2012

Italian researchers exposed pregnant mice to WiFi signals (2.45 GHz) at high levels for 2 hours daily throughout pregnancy to study effects on their offspring's immune system development. They found no detrimental effects on T cell development, immune cell counts, or immune function in the offspring at either 5 weeks or 26 weeks of age. This suggests that prenatal WiFi exposure may not harm developing immune systems, though the study used exposure levels much higher than typical human exposure.

DNA & Genetic DamageNo Effects Found

Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells.

Bourthoumieu S et al. · 2012

Researchers exposed human embryonic cells to cell phone radiation (GSM-900 MHz) for 24 hours at various intensities to see if it would activate p53, a crucial protein that helps protect cells from DNA damage and cancer. The study found no significant changes in p53 expression or activation at any exposure level tested, including levels up to 4 W/kg. This suggests that GSM cell phone radiation may not trigger this particular cellular stress response in embryonic cells.

Reproductive HealthNo Effects Found

The influence of 1800 MHz GSM-like signals on blood chemistry and oxidative stress in non-pregnant and pregnant rabbits.

Kismali G, Ozgur E, Guler G, Akcay A, Sel T, Seyhan N. · 2012

Researchers exposed pregnant and non-pregnant rabbits to cell phone-like radiation for 15 minutes daily for a week to study potential health effects during pregnancy. While the study found no evidence of oxidative stress (cellular damage from harmful molecules), it did detect changes in blood chemistry markers, particularly enzymes that indicate heart muscle stress. The findings suggest that even brief daily exposure to radiofrequency radiation may affect certain biological processes, especially during pregnancy.

Oxidative StressNo Effects Found

Effects of 837 and 1950 MHz radiofrequency radiation exposure alone or combined on oxidative stress in MCF10A cells.

Hong MN et al. · 2012

Researchers exposed human breast tissue cells to cell phone frequencies (837 MHz and 1950 MHz) at high power levels for 2 hours to test whether radiofrequency radiation causes oxidative stress, a type of cellular damage linked to disease. The study found no signs of oxidative stress in the cells, even when exposed to both frequencies simultaneously. This suggests that under these specific laboratory conditions, RF radiation did not trigger the cellular damage processes that scientists look for as early warning signs of health effects.

Microwave electromagnetic field regulates gene expression in T-lymphoblastoid leukemia CCRF-CEM cell line exposed to 900 MHz.

Trivino Pardo JC, Grimaldi S, Taranta M, Naldi I, Cinti C. · 2012

Italian researchers exposed leukemia cells to 900 MHz microwave radiation (the same frequency used by many cell phones) and found that it altered gene expression patterns within the cells. The study identified specific biological pathways that were disrupted by the electromagnetic field exposure. This suggests that cell phone frequency radiation can trigger measurable changes at the genetic level in cancer cells.

Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields.

Teven CM et al. · 2012

University of Chicago researchers exposed bone-forming stem cells to high-frequency electromagnetic fields at 27.1 MHz using an FDA-approved device called ActiPatch. They found that this exposure significantly increased the cells' ability to form bone tissue, triggering multiple markers of bone development without affecting cell growth rates. This suggests electromagnetic field therapy could potentially help repair bone defects in patients who lack sufficient natural bone tissue for reconstruction.

Reproductive Health100 citations

Evidence for mobile phone radiation exposure effects on reproductive pattern of male rats: Role of ROS.

Kesari KK, Behari J. · 2012

Researchers exposed male rats to mobile phone radiation for 2 hours daily over 45 days and found significant damage to their reproductive health. The exposed rats had lower testosterone levels, damaged sperm structure, and produced fewer offspring that weighed less than normal. The scientists believe this damage occurs because the radiation triggers harmful reactive oxygen species (free radicals) that attack reproductive cells.

Effect of exposure to radio frequency radiation emitted by cell phone on the developing dorsal root ganglion of chick embryo: a light microscopic study.

Ingole IV, Ghosh SK. · 2012

Researchers exposed developing chick embryos to cell phone radiation and examined the effects on nerve cells in the spinal cord area (dorsal root ganglion neurons). They found that exposure caused dose-dependent damage to these developing nerve cells, meaning higher doses caused more damage. The damage persisted even when researchers gave the embryos breaks between exposures, suggesting the effects weren't easily reversed.

Effects of radiofrequency radiation on human ferritin: an in vitro enzymun assay.

Fattahi-Asl J et al. · 2012

Researchers exposed human blood serum samples to cell phone radiation at 900 MHz for 30 minutes and found that ferritin levels (a protein that stores iron in the body) decreased significantly compared to unexposed samples. The exposed samples showed ferritin levels drop from 87.25 to 84.94 micrograms per liter, a statistically significant 2.6% reduction. This suggests that cell phone radiation may interfere with iron storage proteins in blood, potentially affecting how our bodies manage iron metabolism.

Effect of 900 MHz radio frequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the brain.

Dasdag S, Akdag MZ, Kizil G, Kizil M, Cakir DU, Yokus B. · 2012

Turkish researchers exposed rats to 900 MHz radiofrequency radiation (the same frequency used by many cell phones) for 2 hours daily over 10 months to study brain effects. They found significant increases in protein carbonyl, a marker of protein damage, along with elevated levels of beta amyloid protein and malondialdehyde in the exposed rats' brains. These findings suggest that long-term cell phone radiation exposure may damage brain proteins, which could have implications for neurological health.

Single-strand DNA breaks in human hair root cells exposed to mobile phone radiation.

Cam ST, Seyhan N. · 2012

Researchers collected hair samples from eight people before and after they used a mobile phone for 15 and 30 minutes, then tested for DNA damage in the hair root cells. They found that just 15 minutes of phone use caused significant DNA breaks in cells near the ear, with even more damage after 30 minutes. This suggests that everyday mobile phone use can damage DNA in nearby tissues within minutes of exposure.

Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems.

Pilla AA. · 2012

Researchers exposed cells to pulsed radiofrequency electromagnetic fields and found they immediately triggered a nearly 3-fold increase in nitric oxide production within seconds. Nitric oxide is a crucial signaling molecule that helps regulate blood flow, immune responses, and healing processes in the body. This study provides the first real-time evidence that non-thermal EMF exposure can rapidly alter this important cellular signaling pathway.

Reproductive Health100 citations

Evidence for mobile phone radiation exposure effects on reproductive pattern of male rats: role of ROS.

Kesari KK, Behari J. · 2012

Researchers exposed male rats to mobile phone radiation for 2 hours daily over 45 days and found significant damage to their reproductive health. The exposed rats had lower testosterone levels, damaged sperm cells, and fewer offspring that weighed less than normal. The study suggests this damage occurs through oxidative stress (cellular damage from unstable molecules called free radicals).

Induction of an adaptive response in human blood lymphocytes exposed to radiofrequencyfields: influence of the universal mobile telecommunication system (UMTS) signal and the specific absorption rate.

Zeni O et al. · 2012

Researchers exposed human immune cells (lymphocytes) to 3G cell phone radiation at various power levels for 20 hours, then treated them with a DNA-damaging chemical. They discovered that cells pre-exposed to radiation at 0.3 watts per kilogram showed less genetic damage than unexposed cells, suggesting the radiation triggered protective mechanisms. This adaptive response indicates that low-level radiofrequency exposure may prime cells to better defend against subsequent toxic challenges.

A 1.8-GHz radiofrequency radiation induces EGF receptor clustering and phosphorylation in cultured human amniotic (FL) cells. Int J Radiat Biol. 88(3):239-244, 2012.

Sun W, Shen X, Lu D, Fu Y, Lu D, Chiang H · 2012

Cell phone radiation (1.8 GHz) activated growth receptors in human cells after just 15 minutes of exposure. The effects occurred at radiation levels of 0.5 W/kg and higher but not at 0.1 W/kg, showing radiofrequency radiation can directly trigger cellular responses that control cell growth and communication.

Monitoring dynamic reactions of red blood cells to UHF electromagnetic waves radiation using a novel micro-imaging technology.

Ruan P, Yong J, Shen H, Zheng X · 2012

Researchers exposed human red blood cells to cell phone-frequency radiation (900 MHz) at different power levels. Low-power exposure caused no changes, but higher power levels significantly altered cell shape, size, and hemoglobin properties, suggesting EMF exposure above certain thresholds can damage blood cells.

Calcium-binding proteins and GFAP immunoreactivity alterations in murine hippocampus after 1 month of exposure to 835MHz radiofrequency at SAR values of 1.6 and 4.0W/kg.

Maskey D, Kim HJ, Kim HG, Kim MJ · 2012

Researchers exposed mice to cell phone frequency radiation (835 MHz) for one month at power levels similar to heavy phone use. They found significant damage to brain cells in the hippocampus, including loss of protective calcium-binding proteins and signs of brain injury that worsened at higher exposure levels. This suggests that prolonged radiofrequency exposure may harm critical brain regions involved in memory and learning.

The genotoxic effect of radiofrequency waves on mouse brain.

Karaca E et al. · 2012

Researchers exposed mouse brain cells to radiofrequency radiation at 10.7 GHz (similar to cell phone frequencies) and found dramatic genetic damage. The radiation caused an 11-fold increase in micronuclei formation, which indicates DNA breaks and chromosomal damage, while also altering genes involved in cell death and survival. This laboratory study demonstrates that RF radiation at levels comparable to cell phone exposure can directly damage brain cell DNA.

The toxic effects of mobile phone radiofrequency (940MHz) on the structure of calf thymus DNA.

Hekmat A, Saboury AA, Moosavi-Movahedi AA. · 2012

Researchers exposed DNA samples to mobile phone radiation (940 MHz) and found that the radiation caused permanent structural changes to the DNA molecules. The DNA became less stable, changed shape, and showed signs of damage that persisted even two hours after exposure ended. This suggests that radiofrequency radiation from mobile phones can directly alter DNA structure at the molecular level.

Oxidative stress induced by 1.8 GHz radio frequency electromagnetic radiation and effects of garlic extract in rats.

Avci B, Akar A, Bilgici B, Tunçel ÖK. · 2012

Researchers exposed rats to 1.8 GHz radiofrequency radiation (similar to cell phone frequencies) for one hour daily over three weeks at levels comparable to phone use. The radiation caused protein damage in brain tissue and increased nitric oxide levels in blood, indicating oxidative stress. When rats were given garlic extract alongside the radiation exposure, the brain protein damage was significantly reduced.

Further Reading

For a comprehensive exploration of EMF health effects and practical protection strategies, explore these books by R Blank and Dr. Martin Blank.