Köktürk S et al. · 2013
Researchers exposed rats to electromagnetic fields during pre- and postnatal periods until postnatal day 80, with one group receiving daily oral Lycopersicon esculentum extract at approximately 2 g/kg. Compared to unexposed controls, EMF-exposed rats showed a significant increase in caspase-3-labeled Purkinje neurons and granule cells, and Purkinje neurons exhibited dark neuron degenerative changes. Rats given the extract alongside EMF exposure had significantly fewer caspase-3-labeled neurons and fewer dark Purkinje neurons than EMF-only rats. The authors concluded that Lycopersicon esculentum exerted a protective effect against EMF-induced apoptosis and neurodegeneration in the cerebellum.
Aït-Aïssa S et al. · 2013
French researchers exposed pregnant rats and their offspring to WiFi signals (2.4 GHz) from pregnancy through 5 weeks after birth, then examined their brains for signs of cellular stress and damage. They found no differences in stress markers between WiFi-exposed and unexposed rat pups, even at exposure levels up to 4 W/kg. The study suggests that WiFi exposure during critical developmental periods may not cause detectable brain damage in young rats.
Nasri K, Daghfous D, Landoulsi A. · 2013
The study evaluated the effects of sub-lethal microwave radiation on Salmonella typhimurium. The bacteria were exposed to a dose of 3600 J delivered as a 40-second exposure at 90 W. Exposure significantly inhibited cellular growth. The treatment increased the effectiveness of most tested antibiotics, with exposed bacteria showing new or improved sensitivity. Gas chromatography analysis showed an increase in unsaturated fatty acids, and the bacteria became more sensitive to sodium deoxycholate and released more extracellular proteins, indicating membrane weakening.
Sefidbakht Y et al. · 2013
Researchers used a rectangular waveguide system to expose luciferase to 940 MHz electromagnetic fields. Exposed luciferase showed significantly higher activity and smaller hydrodynamic radii than unexposed samples. Exposed samples also had less tendency to form aggregates. Dielectric measurements indicated changes related to disaggregation potency.
Thielens A, Vermeeren G, Kurup D, Joseph W, Martens L. · 2013
Compliance boundaries and allowed output powers were determined for the front, back, and side of antennas based on the root-mean-squared electric field, whole-body averaged SAR, and 10 g averaged SAR in the limbs and head and trunk. The study used ICNIRP basic restrictions and reference levels for both general public and occupational exposure. Antennas were designed for GSM900, GSM1800, HSPA, and LTE with output powers up to 300 W at individual frequencies. Boundaries were estimated using finite-difference time-domain simulations with the Virtual Family Male for three directions at 800, 900, 1800, and 2600 MHz.
Simon D et al. · 2013
Researchers exposed reconstructed epidermis models with and without melanocytes to 900 MHz GSM radiation at 2 mW/g for 6 hours. No changes were observed in epidermal architecture, epidermal markers, apoptotic cells, p53 induction, melanocyte location, dendricity, or melanin transfer after exposure. Loricrin and cytokeratin 14 decreased significantly at 6 hours, but all marker levels increased at 24 hours compared to 6 hours, alongside decreased 20S proteasome activity. The presence or absence of melanocytes did not affect the response of the reconstructed epidermis to exposure.
Atlı Şekeroğlu Z, Akar A, Sekeroğlu V. · 2013
Researchers investigated the cytogenotoxic effects of 900 MHz radiofrequency electromagnetic fields on bone marrow cells of immature and mature rats. Rats in the treatment groups were exposed to RF-EMF for 2 hours per day for 45 days. Significant differences were observed in chromosome aberrations, micronucleus frequency, mitotic index, and ratio of polychromatic erythrocytes in all treatment and recovery groups. A 15-day recovery period after exposure did not reduce the damage to the same extent as the corresponding control groups.
Unknown authors · 2013
Mandalà M et al. · 2013
Researchers conducted a study to verify whether Bluetooth devices reduce the auditory nerve effects seen with direct mobile phone electromagnetic field exposure, using the same experimental protocol as a prior investigation. Twelve patients underwent retrosigmoid vestibular neurectomy to treat definite unilateral Ménière's disease while being monitored with acoustically evoked CNAPs during direct mobile phone or Bluetooth headset exposure. Bluetooth electromagnetic fields did not produce any significant change in cochlear nerve activity, while mobile phone electromagnetic fields caused a significant decrease in CNAP amplitude and an increase in latency in all subjects.
Zhijian C et al. · 2013
The study used protein microarray to examine protein expression in human B lymphoblastoid cells intermittently exposed to 1.8-GHz GSM radiofrequency radiation at a specific absorption rate of 2.0 W/kg for 24 hours. The analysis identified 27 differentially expressed proteins associated with DNA damage repair, apoptosis, oncogenesis, cell cycle, and proliferation, with a fold change greater than 1.5 and P<0.05. Western blot validation confirmed that RPA32 expression was significantly down-regulated and p73 expression was significantly up-regulated in the exposed group (P<0.05).
Sun W, Shen X, Lu D, Lu D, Chiang H · 2013
The radiofrequency radiation induced EGF receptor clustering and enhanced phosphorylation on tyrosine-1173 at the higher absorption rates but not at 0.1 W/kg. A 2 μT incoherent magnetic field alone did not significantly affect receptor clustering or phosphorylation. When applied together, the incoherent magnetic field completely inhibited the radiofrequency radiation effects at 0.5, 1.0, and 2.0 W/kg but not at 4.0 W/kg.
Kuehn S, Kelsh MA, Kuster N, Sheppard AR, Shum M. · 2013
Researchers measured SARs in phantoms with mobile phones operating at maximum antenna input power to evaluate design factors such as shape, antenna design, communication technology, and test date over a 7-year period. Service technology accounted for the greatest variability in compliance test SARs, ranging from AMPS highest to GSM lowest. The dominant factor for SARs during use is the time-averaged antenna input power, which may be much less than the maximum power used in testing. Phone shape, antenna type, and orientation were significant but only up to a factor of 2, and SAR in the tilt position was significantly smaller than in the touch position. External antennas produced greater SARs than internal ones, and brick and clamshell phones produced greater SARs than slide phones.
Ahlers MT, Ammermüller J · 2013
Researchers studied possible non-thermal effects of RF-EMF on retinal ganglion cells in vitro under constant temperature. Mouse retinae were exposed to GSM-900, GSM-1800, and UMTS at SARs of 0, 0.02, 0.2, 2, and 20 W/kg with temperature controlled within ±0.5 to 1°C. Light responses were recorded before, during, and up to 35 minutes after exposure under double-blind conditions. Comparison of sham and actual exposure distance values showed no significant differences, and regression analysis found no consistent SAR dependence. The authors concluded no acute effects on retinal ganglion cell responses at SARs up to 20 W/kg.
Ahlers MT, Ammermüller J. · 2013
German researchers exposed isolated mouse retina cells to mobile phone radiation (GSM-900, GSM-1800, and UMTS) at various power levels while carefully controlling temperature. They found no changes in how these vision-critical cells responded to light stimuli, even at radiation levels 10 times higher than typical phone use. This suggests mobile phone radiation doesn't directly interfere with retinal function under controlled laboratory conditions.
Ketabi N, Mobasheri H, Faraji-Dana R. · 2013
Researchers investigated the effects of ultra high frequency nonionizing electromagnetic fields on the channel activities of the nanopore forming protein OmpF porin. Using the voltage clamp technique on an artificial bilayer, they exposed the pore to electromagnetic fields at 910 to 990 MHz and found that the frequency of channel gating and voltage sensitivity increased, while conductance remained unchanged. No changes in membrane capacitance or permeability were identified, and the energy transferred to nano-environments was estimated to address possible thermal effects.
Kim HS et al. · 2013
Male Sprague-Dawley rats were divided into cage-control, sham-exposed, and RFID-exposed groups and exposed to 915 MHz RFID for 8 h daily, 5 days per week, for 2 or 16 weeks. The whole-body average specific absorption rate was 4 W/kg. FDG-PET images were obtained the day after RFID exposure using micro-PET with a FDG tracer, and the relative cerebral glucose metabolic rate was unchanged in the frontal, temporal and parietal cortexes of exposed rats compared with cage-control and sham-exposed groups.
Kim HS et al. · 2013
Researchers exposed rats to 915 MHz RFID radiation for up to 16 weeks at high intensity levels (4 W/kg SAR) and measured brain glucose metabolism using advanced PET scanning. They found no changes in how the brain processed glucose in any region examined, suggesting this type of radiofrequency exposure didn't alter basic brain energy function. This matters because brain glucose metabolism is a fundamental indicator of neural activity and health.
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
Researchers exposed primary cultured cortical neurons from newborn Sprague-Dawley rats to pulsed 2.45 GHz radiofrequency electromagnetic fields for 10 minutes. Exposure significantly decreased cellular viability and increased apoptotic nuclei, CDK5 activity, the p25 to p35 ratio, and tau phosphorylation at Ser404. CDK5 expression did not change significantly after exposure. A CDK5 inhibitor blocked the exposure-induced decrease in cellular viability and tau hyperphosphorylation but did not significantly block apoptosis.
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
Researchers exposed newborn rat brain cells to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwaves) for just 10 minutes and found significant neuronal damage. The brain cells showed decreased viability, increased cell death, and abnormal protein changes associated with neurodegenerative diseases like Alzheimer's. The study identified a specific cellular pathway (p25/CDK5) that appears to drive this RF-induced brain cell injury.
Gasmelseed A, Yunus J. · 2013
Researchers investigated the interaction of a dipole antenna with a human eye model in the presence of a metamaterial. They used a three-dimensional anatomical model of the human eye with 1.25 mm resolution. The finite difference time domain method with convolutional perfectly matched layer formulation was used. The dipole antenna operated at 900 MHz driven by a modulated Gaussian pulse.
Tong J, Chen S, Liu XM, Hao DM · 2013
Researchers recorded hippocampal CA1 neuron activity in rats exposed to 900 MHz electromagnetic radiation at 10 W/m2 using glass electrode extracellular recording and a polygraph. Discharge frequency of hippocampal CA1 neurons was reduced after exposure, though the change in scale was not obvious. Electromagnetic radiation might change the spontaneous discharge patterns of hippocampus CA1 region neurons, making the explosive discharge pattern increase obviously. The researchers suggested that these changes may lead to a decrease in the ability of learning and memory.
Tong J, Chen S, Liu XM, Hao DM. · 2013
Chinese researchers exposed rats to 900 MHz cell phone radiation and measured brain activity in the hippocampus, which controls learning and memory. The radiation disrupted normal neuron firing patterns and increased abnormal brain cell activity, potentially impairing cognitive function.
Gurbuz N, Sirav B, Colbay M, Yetkin I, Seyhan N. · 2013
Researchers exposed male Wistar albino rats to 1800 MHz or 2100 MHz radiofrequency radiation for 30 min per day, 6 days per week, for either a month or two months. They measured micronucleus frequency in exfoliated bladder cells as an indicator of genotoxic damage. No significant differences in micronucleus frequency were found between any exposed group and its corresponding control group, nor between the two 2100 MHz exposure durations.
Unknown authors · 2013
Researchers assessed potential organ damage using histopathological study. Exposed rats showed significant differences in Olive moment and percent DNA in blood compared to controls. Hyperchromasia was observed in ovaries, and reduced germ cells with cell disorganization were seen in testes with increasing SARs.
Behari J, Nirala JP. · 2013
A SAR measurement system was developed for a brain phantom in a Perspex box. The phantom box volume matched a small rat and was illuminated by a 3G mobile phone at 1718.5 MHz. A moving platform changed the phone's angular position at 2 degrees per minute up to 20 degrees while induced fields were measured. SAR values computed from induced fields were higher than those from induced field measurements alone and varied with angular position, but remained well below human safety criteria. SAR was also measured by temperature rise and compared with the induced-field results, and measurements were repeated in a 10 g phantom in a cubical box for safety criteria comparison.
