Mahdavi SM, Sahraei H, Yaghmaei P, Tavakoli H. · 2014
Researchers studied the effects of extremely low frequency electromagnetic field (ELF-EMF) exposure at 1 and 5 Hz on behavioral, hormonal, and metabolic changes in male Wistar rats. Plasma ACTH concentration increased in both frequency groups, while noradrenaline concentration showed an overall reduction.
Salunke BP, Umathe SN, Chavan JG · 2014
Researchers exposed Swiss albino mice to an extremely low frequency magnetic field (50 Hz, 10 G) for 8 hours per day for up to 120 days to study obsessive-compulsive disorder-like behavior. OCD-like behavior was measured using the marble burying behavior test, and the results showed that the magnetic field induced time-dependent marble burying behavior on each exposure day tested. A nitric oxide precursor worsened the OCD-like behavior, while nitric oxide synthase inhibitors reduced it, with corresponding changes in nitric oxide levels.
Chen Y, Hong L, Zeng Y, Shen Y, Zeng Q. · 2014
Researchers exposed mouse embryonic fibroblasts to a 50 Hz power frequency magnetic field at 2 mT across several time points and measured autophagy markers. A significant increase in autophagic markers was observed at 6 hours, including higher LC3-II levels, increased GFP-LC3 puncta formation, and increased numbers of autophagic vacuoles. The increase in autophagic markers was the result of enhanced autophagic flux and not the suppression of lysosomal function, and the autophagic process involved reactive oxygen species and was independent of the mTOR signaling pathway.
Kantar Gok D et al. · 2014
Researchers exposed rats to 50 Hz electric fields (like those from power lines) for up to four weeks. High-intensity exposure significantly reduced brain responses that help detect sound changes, while increasing brain damage markers. This suggests electric field exposure may impair auditory processing abilities.
Luukkonen J, Liimatainen A, Juutilainen J, Naarala J · 2014
Researchers exposed human SH-SY5Y neuroblastoma cells to a 50-Hz, 100-μT magnetic field for 24 hours, followed by a 3-hour exposure to menadione. The study aimed to investigate cellular changes occurring during the first 24 hours of magnetic field exposure and whether those changes could lead to genomic instability in the progeny of exposed cells. Magnetic field exposure was associated with increased micronuclei at 8 and 15 days after exposure, increased mitochondrial activity at 8 days, and increased reactive oxygen species production and lipid peroxidation at 15 days. The researchers suggest that magnetic field exposure disturbs oxidative balance immediately after exposure, and that persistently elevated levels of micronuclei were found in the progeny of exposed cells.
Salunke BP, Umathe SN, Chavan JG · 2014
Researchers exposed mice to 50 Hz magnetic fields (power line frequency) for 8 hours daily up to 120 days. This caused obsessive-compulsive behaviors by increasing nitric oxide levels in brain regions. The study suggests household electrical frequencies may affect brain chemistry and behavior.
Duan Y, Wang Z, Zhang H, He Y, Fan R, Cheng Y, Sun G, Sun X. · 2014
Researchers exposed mice to 50 Hz magnetic fields (the same frequency as power lines) for 28 days and found significant brain changes in the hippocampus, a region critical for memory and learning. The exposure disrupted brain chemistry by increasing glutamate levels and damaging cellular signaling pathways that are essential for proper brain function. Importantly, the study also showed that these harmful effects could be reversed with a natural antioxidant treatment.
Gao X, Wang X, Chen F, Qi H, Wang X, Ming D, Zhou P. · 2014
Researchers conducted magnetic stimulation experiments at 1 Hz and 10 mT for 20 minutes and analyzed spontaneous EEG activity from 10 subjects. Compared with a sham exposure group, EEG power in the theta band (3.5-7.5 Hz) and lower-alpha band (7.5-10 Hz) increased significantly after magnetic stimulation. In an auditory oddball task, the latency period of P300 extended and its amplitude decreased.
Kantar Gok D et al. · 2014
Researchers exposed rats to electric fields from power lines for up to four weeks. The strongest exposure significantly impaired the brain's ability to detect sound changes, a function crucial for attention and learning, while also causing harmful cellular damage in brain tissue.
Li Y, Yan X, Liu J, Li L, Hu X, Sun H, Tian J. · 2014
Researchers exposed newborn rat nerve cells to 50 Hz electromagnetic fields (power line frequency) for two hours. The exposure increased production of BDNF, a protein essential for nerve growth and brain health, by triggering calcium flow into cells and activating specific cellular pathways.
Salunke BP, Umathe SN, Chavan JG. · 2014
Researchers exposed mice to 50 Hz magnetic fields from power lines for 8 hours daily up to 120 days. The mice developed obsessive-compulsive behaviors and showed increased nitric oxide levels in brain regions controlling behavior, suggesting power-frequency fields can alter brain chemistry.
Spasić S, Kesić S, Stojadinović G, Petković B, Todorović D. · 2014
Researchers studied the effects of a static magnetic field (SMF, 2 mT) and an extremely low frequency magnetic field (ELF MF, 50 Hz, 2 mT) on neuronal population activity in adult longhorn beetles Morimus funereus. The effects of prolonged and repeated ELF MF exposure on local field potentials were irreversible within the investigated time frame. The researchers did not prove with the methods used that exposure to the SMF for 5 min produces any effects on neuronal population activity.
Hwang Y, Ahn J, Mun J, Bae S, Jeong YU, Vinokurov NA, Kim P. · 2014
Researchers irradiated the ear skin of a live anesthetized mouse with pulsed THz waves and monitored the response at the cellular level using intravital laser-scanning confocal microscopy. The pulsed THz wave used was 2.7 THz with a 4 μs pulsewidth, 61.4 μJ per pulse, at a 3 Hz repetition rate, applied at an average power of 260 mW/cm2 for 30 minutes. No temperature change was detected at the skin surface, while a massive recruitment of newly infiltrated neutrophils was observed in the irradiated area after 6 hours.
Davanipour Z, Tseng C-C, Lee PJ, Markides KS, Sobel E. · 2014
The study included 3050 Mexican Americans aged 65 and older from the H-EPESE study, and severe cognitive dysfunction was defined as an MMSE score below 10. Occupational extremely low frequency magnetic field exposure was classified using a methodology from earlier studies. Univariate odds ratios were 3.4 for high exposure and 1.7 for medium or high exposure, with similar results in multivariate models. Interactions between medium/high or high exposure and smoking history or age group were statistically significant, particularly for those aged 75 and older. The authors concluded that high or medium/high occupational exposure may increase the risk of severe cognitive dysfunction, and that smoking and older age may increase the deleterious effect.
Davanipour Z, Tseng C-C, Lee PJ, Markides KS, Sobel E. · 2014
Researchers studied over 3,000 elderly Mexican Americans to see if working in jobs with high magnetic field exposure (like electricians or welders) was linked to severe cognitive problems. They found that people who worked in high magnetic field occupations were 3.4 times more likely to develop severe cognitive dysfunction, with the risk being even higher for older adults and smokers. This is the first study to specifically examine the connection between workplace magnetic field exposure and severe cognitive decline in older adults.
Mahdavi SM, Sahraei H, Yaghmaei P, Tavakoli H. · 2014
Researchers exposed male rats to extremely low frequency electromagnetic fields at 1 Hz and 5 Hz to study effects on stress hormones and behavior. They found that these exposures altered stress hormone levels (increasing ACTH while decreasing noradrenaline) and changed glucose metabolism differently depending on the frequency used. The study demonstrates that even very low frequency EMF exposures can disrupt the body's stress response system in measurable ways.
de Groot MW, Kock MD, Westerink RH. · 2014
Researchers investigated acute (30 min) and sub-chronic (48 h) exposure to 50 Hz ELF-EMF on naïve and chemically stressed PC12 cells. Acute exposure up to 1000 μT did not affect basal or depolarization-evoked calcium levels in naïve cells. Sub-chronic exposure up to 1000 μT had no consistent effects on calcium homeostasis, ROS production, or membrane integrity in naïve cells. In chemically stressed cells, both acute and sub-chronic exposure also failed to exert consistent effects on calcium homeostasis, ROS production, and membrane integrity. The authors concluded that exposure up to 1000 μT does not induce neurotoxic effects in vitro in either cell type.
Li Y, Zhang C, Song T. · 2014
Researchers exposed Sprague-Dawley rats to Morris water maze training, ELF-MF exposure (50 Hz, 100 microT), or combined training and exposure for 90 days, with normal rats as controls. Previous training improved spatial acquisition in the Morris water maze and this effect lasted at least 90 days. However, this improvement was not observed during the probe trial. ELF-MF exposure did not significantly differ from controls and did not interfere with training-related improvements.
Sorahan T, Mohammed N · 2014
The mortality experienced by a cohort of 73,051 employees of the former Central Electricity Generating Board of England and Wales was investigated for the period 1973–2010. Poisson regression was used to calculate relative risks (rate ratios) of developing any of the three diseases under investigation for categories of lifetime, distant (lagged) and recent (lugged) exposure. No statistically significant trends were shown for risks of any of these diseases to increase with estimates of lifetime, recent or distant exposure to magnetic fields. There is no convincing evidence that UK electricity generation and transmission workers have suffered elevated risks from neurodegenerative diseases as a consequence of exposure to magnetic fields.
de Groot MW, Kock MD, Westerink RH. · 2014
Researchers exposed nerve cells (PC12 cells) to 50 Hz magnetic fields at levels up to 1,000 microtesla for periods ranging from 30 minutes to 48 hours. They tested both healthy cells and chemically-stressed cells that were more vulnerable to damage. The magnetic field exposure caused no detectable effects on calcium levels, cellular damage, or oxidative stress in either type of cell.
Jin YB et al. · 2014
Researchers assessed DNA damage using comet assays in mouse and human cell lines exposed to 60-Hz, 1 mT ELF-MF for 4 or 16 hours. Cells exposed to ELF-MF alone showed no significant DNA damage compared to unexposed cells. No synergistic or additive DNA damage occurred when ELF-MF was combined with ionizing radiation, hydrogen peroxide, or c-Myc activation.
de Groot MW, Kock MD, Westerink RH. · 2014
Researchers exposed nerve cells (PC12 cells) to 50 Hz magnetic fields at extremely high levels - up to 1000 microteslas, which is 10,000 times stronger than typical background exposure. They tested both healthy cells and chemically-stressed cells that were more vulnerable to damage. The study found no toxic effects on the nerve cells' calcium balance, oxidative stress levels, or cell membrane integrity, even at these extraordinarily high exposure levels.
Maestú C et al. · 2013
Spanish researchers tested whether very low-intensity 8 Hz magnetic fields could help women with fibromyalgia, a chronic pain condition. After eight weekly sessions, patients receiving real magnetic stimulation showed significant improvements in pain thresholds, daily functioning, chronic pain levels, and sleep quality compared to those receiving fake treatment. The benefits appeared quickly for pain relief but took six weeks to develop for other symptoms, suggesting magnetic fields may offer a safe treatment option for fibromyalgia patients.
Lustenberger C et al. · 2013
Swiss researchers exposed 16 men to pulsed radiofrequency radiation (similar to cell phone signals) throughout entire nights of sleep and measured their brain activity and learning ability. They found that RF exposure altered brain wave patterns during sleep and reduced the participants' ability to improve on a motor skill task by 20% compared to nights without exposure. This suggests that RF radiation can interfere with the brain's natural sleep processes that are essential for learning and memory consolidation.
Kim HJ, Jung J, Park JH, Kim JH, Ko KN, Kim CW. · 2013