3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

Cell Phone Radiation Research

RF Radiation

Research on electromagnetic radiation from mobile phones, including 2G, 3G, 4G LTE, and 5G NR signals.

1,326
Studies
73%
Showed Bioeffects
1
EMF Type
700 MHz - 2.7 GHz
Frequency

Related Studies (1,326)

Effects of GSM 1800 MHz radiofrequency electromagnetic fields on DNA damage in Chinese hamster lung cells.

Zhang DY, Xu ZP, Chiang H, Lu DQ, Zeng QL. · 2006

Chinese researchers exposed hamster lung cells to cell phone radiation at 1800 MHz (the frequency used by GSM networks) for either 1 or 24 hours to see if it would damage DNA. They found that 24-hour exposure at high intensity (3.0 W/kg) significantly increased DNA damage markers compared to unexposed cells, while 1-hour exposure showed no effect. This suggests that prolonged exposure to cell phone-type radiation may harm cellular DNA.

Protein Kinase C Activity in developing rat brain cells exposed to 2.45 GHz radiation

Paulraj R, Behari J · 2006

Researchers exposed developing rat brains to 2.45 GHz radiation (the same frequency as WiFi and microwaves) for 2 hours daily over 35 days. They found significant decreases in protein kinase C activity in the hippocampus, a brain region crucial for learning and memory, plus increased glial cells which can indicate brain inflammation. The study suggests that chronic microwave exposure during brain development may interfere with normal growth and cellular function.

Cellular EffectsNo Effects Found

Gene expression analysis of a human lymphoblastoma cell line exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field.

Chauhan V et al. · 2006

Researchers exposed human immune cells to 1.9 GHz radiofrequency radiation at levels similar to cell phone use (1-10 W/kg SAR) to see if it triggered cellular stress responses. They measured key stress markers including heat shock proteins and proto-oncogenes that typically activate when cells are damaged. The study found no significant changes in these stress indicators, suggesting the RF exposure did not cause detectable cellular stress under these laboratory conditions.

GSM radiation triggers seizures and increases cerebral c-Fos positivity in rats pretreated with subconvulsive doses of picrotoxin.

Lopez-Martin E et al. · 2006

Spanish researchers studied whether cell phone radiation could trigger seizures in rats that were already vulnerable to seizures (treated with a brain chemical called picrotoxin). When exposed to 900 MHz GSM radiation similar to mobile phones for 2 hours, these seizure-prone rats developed actual seizures and showed increased brain activity markers, while control rats without radiation exposure did not seize. This suggests cell phone radiation might worsen seizure risk in individuals who are already neurologically vulnerable.

DNA & Genetic DamageNo Effects Found

Analysis of proto-oncogene and heat-shock protein gene expression in human derived cell-lines exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field.

Chauhan V et al. · 2006

Researchers exposed human immune cells to 1.9 GHz radiofrequency radiation (similar to cell phone signals) at power levels of 1 and 10 watts per kilogram for 6 hours to see if it would trigger stress responses or activate genes linked to cancer development. They found no changes in stress proteins or cancer-related genes at either power level, while heat treatment (as a positive control) did trigger the expected cellular stress responses.

Cancer & TumorsNo Effects Found

No effects of radiofrequency radiation on 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-Induced tumorigenesis in female Wistar rats.

Heikkinen et al. · 2006

Finnish researchers exposed female rats to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 2 hours daily over 2 years while also giving them a known cancer-causing chemical in their drinking water. The study aimed to see if RF radiation would make tumors more likely to develop. The researchers found no evidence that RF radiation increased cancer risk, even when combined with a chemical known to cause tumors.

Effects of 900 MHz GSM Wireless Communication Signals on DMBA-Induced Mammary Tumors in Rats.

Yu D, Shen Y, Kuster N, Fu Y, Chiang H. · 2006

Researchers exposed 500 female rats to 900 MHz cell phone radiation (the same frequency used by GSM phones) for 4 hours daily over 26 weeks after giving them a cancer-causing chemical. While the study found no statistically significant increase in mammary tumors from RF exposure, there was a concerning trend toward higher cancer rates in rats exposed to the highest radiation levels, particularly during weeks 15-26.

Brain & Nervous SystemNo Effects Found

Expression of the immediate early gene, c-fos, in fetal brain after whole of gestation exposure of pregnant mice to global system for mobile communication microwaves.

Finnie JW, Cai Z, Blumbergs PC, Manavis J, Kuchel TR. · 2006

Researchers exposed pregnant mice to 900 MHz cell phone radiation for one hour daily throughout pregnancy to see if it would stress developing fetal brains. They measured c-fos, a protein that appears when brain cells are under stress. The study found no difference in stress markers between exposed and unexposed fetal brains, suggesting this level of radiation didn't cause detectable neural stress during development.

DNA & Genetic DamageNo Effects Found

Cytogenetic Studies in Human Blood Lymphocytes Exposed In Vitro to 2.45 GHz or 8.2 GHz Radiofrequency Radiation.

Vijayalaxmi · 2006

Researchers exposed human blood cells to radiofrequency radiation at 2.45 GHz and 8.2 GHz (frequencies used in WiFi and microwave ovens) for 2 hours to see if it caused genetic damage. They found no significant increase in chromosomal damage or DNA breaks compared to unexposed cells. This suggests that short-term RF exposure at these power levels may not directly damage genetic material in blood cells.

Sleep & Circadian RhythmNo Effects Found

1800 MHz electromagnetic field effects on melatonin release from isolated pineal glands.

Sukhotina I, Streckert JR, Bitz AK, Hansen VW, Lerchl A · 2006

Researchers exposed isolated hamster pineal glands (which produce melatonin, the sleep hormone) to cell phone radiation at 1800 MHz for 7 hours at various power levels. Surprisingly, they found that moderate exposure levels actually increased melatonin production, while only the highest level (which caused tissue heating) suppressed it. This challenges the widely-discussed theory that cell phone radiation disrupts sleep by reducing melatonin.

Modest increase in temperature affects ODC activity in L929 cells: low-level radiofrequency radiation does not.

Hoyto A, Sihvonen AP, Alhonen L, Juutilainen J, Naarala J · 2006

Researchers exposed mouse cells to cell phone-level radiofrequency radiation for 24 hours. The RF radiation itself caused no biological effects, but tiny temperature increases (less than 1°C) significantly affected cellular enzyme activity, showing temperature control is crucial in EMF studies.

Cellular EffectsNo Effects Found

Effect of GSM-900 and -1800 signals on the skin of hairless rats. I: 2-hour acute exposures.

Masuda H et al. · 2006

French researchers exposed hairless rats to cell phone radiation (GSM-900 and GSM-1800 signals) for 2 hours at high intensity levels (5 W/kg SAR) and examined their skin tissue for damage. They found no changes in skin thickness, cell death, cell growth patterns, or key skin proteins compared to unexposed animals. This suggests that acute exposure to these cell phone frequencies at high levels does not cause immediate visible damage to skin tissue.

Brain & Nervous SystemNo Effects Found

A study of the effects of cellular telephone microwave radiation on the auditory system in healthy men

Mora R, Crippa B, Mora F, Dellepiane M · 2006

Italian researchers tested whether cell phone radiation affects hearing by exposing 20 healthy men to phone signals (900-1,800 MHz) for 15-30 minutes while measuring their auditory responses. They found no changes in hearing function during or after exposure. This suggests short-term cell phone use doesn't immediately damage the auditory system.

Cellular EffectsNo Effects Found

Effect of GSM-900 and -1800 signals on the skin of hairless rats. II: 12-week chronic exposures.

Sanchez S et al. · 2006

French researchers exposed hairless rats to cell phone radiation (GSM-900 and GSM-1800 signals) for 2 hours daily over 12 weeks to study effects on skin health. They found no significant changes in skin thickness, cell growth patterns, or key structural proteins compared to unexposed rats. This suggests that chronic exposure to these specific cell phone frequencies at the tested levels did not cause detectable skin damage in this animal model.

Effect of acute exposure to microwave from mobile phone on DNA damage and repair of cultured human lens epithelial cells in vitro

Sun LX, Yao K, He JL, Lu DQ, Wang KJ, Li HW. · 2006

Researchers exposed human eye lens cells to mobile phone radiation at different power levels for 2 hours. Lower exposures caused repairable DNA damage, but higher levels (4 W/kg) created permanent breaks cells couldn't fix, suggesting phone radiation may overwhelm the eye's natural repair systems.

Effect of acute exposure to microwave from mobile phone on DNA damage and repair of cultured human lens epithelial cells in vitro.

Sun LX, Yao K, He JL, Lu DQ, Wang KJ, Li HW. · 2006

Researchers exposed human eye lens cells to cell phone radiation for 2 hours at different power levels. Lower levels caused repairable DNA damage, but higher power (4 W/kg) caused permanent breaks cells couldn't fix, suggesting a threshold where radiation overwhelms natural repair.

[Effect of acute exposure to microwave from mobile phone on DNA damage and repair of cultured human lens epithelial cells in vitro.]

Sun LX, Yao K, He JL, Lu DQ, Wang KJ, Li HW. · 2006

Researchers exposed human eye lens cells to cell phone radiation for 2 hours at different power levels to see if it damages DNA. They found that lower exposure levels (up to 3 W/kg) caused temporary DNA breaks that the cells could repair, but higher exposure (4 W/kg) caused permanent DNA damage that cells couldn't fix.

DNA damage and repair induced by acute exposure of microwave from mobile phone on cultured human lens epithelial cells

Sun LX, Yao K, Jiang H, He JL, Lu DQ, Wang KJ, Li HW · 2006

Researchers exposed human eye lens cells to cell phone radiation at different power levels for 2 hours to see if it damaged DNA. They found that lower exposure levels (similar to typical phone use) caused no DNA damage, but higher levels (4 times normal) did cause measurable DNA breaks and reduced cell growth. This suggests there may be a threshold below which cells can repair radiation damage effectively.

DNA & Genetic DamageNo Effects Found

Effect of acute exposure to microwave from mobile phone on DNA damage and repair of cultured human lens epithelial cells in vitro.

Sun LX, Yao K, He JL, Lu DQ, Wang KJ, Li HW · 2006

Chinese researchers exposed human eye lens cells to mobile phone radiation (1.8 GHz) at different power levels for 2 hours to see if it damaged DNA. They found that lower exposure levels (1-3 W/kg SAR) caused either no DNA damage or damage that the cells could repair within an hour, but the highest level (4 W/kg SAR) caused permanent DNA damage that cells couldn't fix.

HSP27 phosphorylation increases after 45 degrees C or 41 degrees C heat shocks but not after non-thermal TDMA or GSM exposures.

Vanderwaal RP, Cha B, Moros EG, Roti Roti JL. · 2006

Scientists tested whether cell phone radiation triggers the same cellular stress response as heat in laboratory cells. While heat clearly activated stress proteins, cell phone signals at levels 5-10 times higher than normal phone use caused no detectable stress response, suggesting different biological effects.

.[Effect of 1.8 GHz radiofrequency electromagnetic fields on the expression of microtubule associated protein 2 in rat neurons]

Zhao R, Zhang SZ, Yao GD, Lu DQ, Jiang H, Xu ZP · 2006

Researchers exposed newborn rat brain cells to 1.8 GHz radiofrequency radiation (similar to cell phone frequencies) at 2 watts per kilogram for 24 hours and found that 34 out of 1,200 genes changed their expression levels. Most notably, a gene called MAP2, which helps maintain the structural framework of brain cells, became significantly more active after radiation exposure.

FAQs: Cell Phones EMF Research

Of 1,326 peer-reviewed studies examining cell phones electromagnetic radiation, 73% found measurable biological effects. These studies span decades of research conducted by scientists worldwide and include both laboratory experiments and epidemiological studies examining the health effects of cell phones radiation exposure.
The BioInitiative Report database includes 1,326 peer-reviewed studies specifically examining cell phones electromagnetic radiation and its potential health effects. These studies have been conducted by researchers worldwide and published in scientific journals. The research examines various biological endpoints including cellular effects, neurological impacts, reproductive health, and other health outcomes.
73% of the 1,326 studies examining cell phones electromagnetic radiation found measurable biological effects. This means that 968 studies documented observable changes when organisms were exposed to cell phones EMF. The remaining studies either found no significant effects or had inconclusive results.