Anane R et al. · 2003
Researchers tested whether whole-body exposure to GSM-900 microwaves affected tumor promotion and progression in female Sprague-Dawley rats with DMBA-induced mammary tumors. Results were negative for tumor latency, multiplicity, and volume, though in the first experiment tumor incidence was higher at 1.4 W/kg but less so at 2.2 W/kg and not at all at 3.5 W/kg. Overall the results were considered rather inconsistent and did not bring new evidence of a co-promoting effect of GSM-900 exposure.
Nakamura H et al. · 2003
Researchers compared microwave exposure to water immersion at matched temperature rises in thirty-six pregnant rats assigned to six groups with 90-minute exposures. No significant differences in uteroplacental circulation or placental endocrine and immune functions were found between rats exposed to 0.6 mW/cm2 microwaves and those immersed at 38 °C. At 3 mW/cm2, microwaves caused significant decreases in uteroplacental blood flow and estradiol compared with rats immersed at 40 °C.
Navarro EA, Sequra J, Portoles M, Gomez-Perretta de Mateo C · 2003
Researchers conducted a health survey near a cellular phone base station operating at DCS-1800 MHz in Murcia, Spain. Statistical analysis showed a significant correlation between declared symptom severity and measured power density, and the higher exposure group reported increased severity.
McNamee et al. · 2003
Researchers examined the effect of 24-hour continuous-wave and pulsed-wave 1.9 GHz radiofrequency fields on primary DNA damage and micronucleus induction in human leukocyte cultures. No significant differences in primary DNA damage were observed between sham controls and any exposed cultures when assessed by the alkaline comet assay immediately after exposure. Similarly, no significant differences were found in micronucleus incidence, micronucleated binucleated cells, binucleated cell frequency, or proliferation index between sham and exposed cultures.
McNamee et al. · 2003
Researchers exposed human white blood cells to 1.9 GHz radiofrequency radiation (similar to what cell phones emit) for 24 hours at power levels up to 10 watts per kilogram. They found no DNA damage or genetic changes in the cells, even after this extended exposure period at levels much higher than typical phone use.
HuberR et al. · 2002
Tice RR, Hook GG, Donner M, McRee DI, Guy AW. · 2002
DNA damage in leukocytes was assessed with the alkaline comet assay and chromosomal damage in lymphocytes with the micronucleus assay. No significant increase in DNA damage was seen after 3 or 24 hours, and no increase in micronucleated lymphocytes occurred after 3 hours. However, 24-hour exposures at 5.0 or 10.0 W/kg significantly increased micronucleated lymphocytes about fourfold, regardless of signal type, modulation, or frequency.
Croft R et al. · 2002
The study tested whether exposure to an active MP affects EEG as a function of time. MP exposure also altered early phase-locked neural responses, attenuating the normal response decrement over time in the 4-8 Hz band, decreasing the response in the 1230 Hz band globally and as a function of time, and increasing midline frontal and lateral posterior responses in the 30-45 Hz band.
Utteridge TD et al. · 2002
Researchers exposed 120 E-mu-Pim1 heterozygous mice and 120 wild-type mice to GSM-modulated 898.4 MHz radiation at SARs of 0.25, 1.0, 2.0, and 4.0 W/kg for 1 hour per day, 5 days per week, for up to 104 weeks. Sham-exposed groups of 120 heterozygous and 120 wild-type mice and an unrestrained negative control group were included. No significant difference in lymphoma incidence was found between exposed and sham-exposed groups at any exposure level. No dose-response effect was detected.
Edelstyn N, Oldershaw A. · 2002
Thirty-eight healthy volunteers were randomly assigned to an experimental group exposed to a 900 MHz mobile phone for 30 minutes or a control group with the phone switched off. Cognitive performance was assessed before exposure and at 15 and 30 minutes post-exposure using six neuropsychological tests. Significant differences appeared after 5 minutes on digit span forwards, spatial span backwards, and serial subtraction, with performance facilitated in the exposed group.
Hietanen M, Hämäläinen A-M, Husman T. · 2002
The study tested the hypothesis that hypersensitive persons perceive symptoms from RF fields using double blind provocation experiments. Twenty volunteers who reported sensitivity to cellular phones participated. Exposure sources were one analogue NMT phone at 900 MHz and two digital GSM phones at 900 and 1800 MHz. Each test session lasted 30 minutes with three or four sessions in random order per day. More symptoms were reported during sham exposure than during real exposure, and no subject could distinguish real from sham exposure.
d'Ambrosio G, MassaR, Scarfi MR, Zeni O · 2002
Researchers exposed human peripheral blood cultures to 1.748 GHz microwaves, either as continuous wave or phase-only modulated wave, for 15 minutes. The study measured cell proliferation kinetics and micronucleus frequency to look for genotoxic effects. No changes in cell proliferation kinetics were found after either type of exposure. A statistically significant micronucleus effect was found following exposure to the phase modulated field, but not after continuous wave exposure. The researchers suggested these results indicate a genotoxic power of the phase modulation itself.
Dubreuil D, Jay T, Edeline JM. · 2002
McNamee JP et al. · 2002
Researchers exposed human white blood cells to cell phone radiation (1.9 GHz) for 2 hours at various power levels to see if it would damage DNA or cause genetic abnormalities. They found no evidence of DNA damage or genetic changes at any exposure level tested, including levels 5 times higher than typical cell phone use. This Canadian government study suggests that short-term radiofrequency exposure may not directly harm genetic material in immune cells.
Beason RC, Semm P. · 2002
Researchers investigated the effects of a pulsed 900 MHz signal modulated at 217 Hz on avian brain neurons. The stimulation changed neural activity in more than half of the brain cells. 76% of responding cells increased their firing rates by an average of 3.5-fold. The remaining responding cells decreased their spontaneous activity rates. The authors suggested these responses indicate potential effects on humans using hand-held cellular phones.
Finnie JW et al. · 2002
The study was designed to examine the effect of long-term exposure to global system for mobile communication (GSM) radiofrequency fields on vascular permeability in murine brains. Mice were given a 60-minute far-field, whole body exposure on each of 5 days per week for 104 weeks at specific absorption rates (SAR) of 0.25, 1.0,2.0 and 4.0 W/kg. In all exposed and control groups, albumin extravasation was minimal and was deemed insignificant.
Shallom JM et al. · 2002
Researchers exposed chick embryos to athermal 915 MHz microwave radiation to test for induction of the stress protein Hsp70. Hsp70 levels increased within 2 hours, reaching a maximum about 30% above controls by 3 hours. Embryos pre-exposed to microwave radiation before hypoxic stress had significantly higher survival after re-oxygenation than non-exposed controls (P < 0.05).
Zhang MB, He JL, Jin LF, Lu DQ. · 2002
Researchers studied whether 2450-MHz microwave radiation interacts with the chemical mitomycin C (MMC) to produce genotoxic effects in human lymphocytes in vitro. Blood cells from a male donor and a female donor were exposed to 2450-MHz microwaves at 5.0 mW/cm2 for 2 h, to MMC alone for 24 h, or to MMC for 24 h following microwave exposure. Microwave exposure alone did not significantly increase comet lengths compared with controls, but combined microwave plus MMC exposure produced significantly longer comet lengths than MMC alone at doses of 0.025 microgram/mL or higher.
Paulraj R, Behari J · 2002
Researchers exposed 35-day-old Wistar rats to low-level continuous 2.45 GHz microwaves for 2 hr/day over 35 days at a power density of 0.34 mW/cm2 with a specific absorption rate of 0.1 W/kg. Exposed rats showed a significant increase in calcium ion efflux and ornithine decarboxylase activity and a significant decrease in calcium-dependent protein kinase activity in brain tissue. The authors suggested that the radiation affects membrane-bound enzymes linked to cell proliferation and differentiation, indicating a possible tumor-promoting role.
Testylier G, Tonduli L, Malabiau R, Debouzy JC · 2002
Rats were exposed to 2.45 GHz continuous wave at 2 or 4 mW/cm(2) for 1 h during the day, or to 800 MHz modulated at 32 Hz at 200 mW/cm(2) for 1 or 14 h during the night. Exposure at 4 mW/cm(2) caused a significant 40% decrease in mean acetylcholine release from hippocampus, maximal at 5 h post exposure. Fourteen-hour nighttime exposure at 800 MHz induced a significant 43% decrease in acetylcholine release during 11 p.m.-4 a.m. compared to control rats.
Tafforeau M et al. · 2002
Researchers exposed flax seedlings to a 1-minute cold shock or a 2-hour GSM telephone radiation at 0.9 GHz and observed epidermal meristem production. They performed a SIMS analysis of inorganic cations in hypocotyl tissue from control and calcium-deprived seedlings. The analysis revealed decreases in calcium, sodium, and potassium and an increase in magnesium without substantially changing the divalent-to-monovalent cation ratio.
Stopczyk D et al. · 2002
Researchers assessed the effect of mobile phone electromagnetic fields on SOD-1 activity and MDA level in human blood platelets exposed to 900 MHz for 1, 3, 5, and 7 minutes. SOD-1 activity was significantly depleted after 1, 5, and 7 minutes of exposure and increased after 3 minutes compared with controls. MDA concentration increased significantly after 1, 5, and 7 minutes and decreased after 3 minutes compared with controls. The authors concluded that oxidative stress from microwave exposure may cause adverse cellular changes and systemic disturbances.
Takahashi S et al. · 2002
Researchers investigated the mutagenic potential of 1.5 GHz electromagnetic near fields using brain tissues of Big Blue mice. Male BBM were locally exposed to EMF in the head region at 2.0, 0.67, and 0 W/kg specific absorption rate for 90 min/day, 5 days/week, for 4 weeks. There was no significant variation in the frequency of independent mutations of the lacI transgene in the brains. Deletion mutations were slightly increased in both the high and low EMF exposure groups as compared with the sham-exposed group, but the differences were not statistically significant.
Bortkiewicz A, Pilacik B, Gadzicka E, Szymczak W. · 2002
Hanada E, Hoshino Y, Oyama H, Watanabe Y, Nose Y. · 2002
Researchers tested the effect of wireless LAN communication on medical electronic equipment and the effect of electronic equipment on wireless LAN communication. They observed nine pieces of electronic equipment in operating mode while transmitting radio waves from a wireless LAN. No equipment malfunction occurred even with the access point very close to the equipment surface during data transmission. Medical equipment caused little change in wireless communication effectiveness, but electric knives and a remote patient monitor reduced the reception rate to about 60%. Wireless LAN speed was temporarily reduced only when a microwave oven was close to and facing the access point.
