Hirose H et al. · 2008
Researchers continuously exposed BALB/3T3 cells to 2.1425 GHz W-CDMA RF fields at SARs of 80 and 800 mW/kg for 6 weeks. They also tested MCA-treated cells and MCA plus TPA-treated cells for tumor promotion and co-promotion effects. No significant differences in transformation frequency were found between RF-exposed groups and sham-exposed controls in any treatment condition. The results suggest that exposure to low-level RF radiation of up to 800 mW/kg does not induce cell transformation.
Hruby R, Neubauer G, Kuster N, Frauscher M · 2008
The study aimed to detect whether long-term exposure to 902-MHz GSM-type wireless communication signals would affect DMBA-induced mammary tumours in female Sprague-Dawley rats. Five hundred female rats were each given a single oral dose of 17 mg DMBA per kg body weight at an age of 46-48 days.
Unknown authors · 2008
Researchers used the SOD-1 mouse model to assess the possible effect of ELF magnetic fields on ALS development. Seven mice per group were exposed to 50 Hz magnetic fields at 100 and 1000 microT(rms) before clinical signs of ALS appeared. Exposure lasted 7 weeks while body weight, motor performance, and life span were monitored. The results showed no evidence of a link between ELF exposure and ALS in this transgenic animal model.
Unknown authors · 2008
Researchers exposed human neutrophils (white blood cells) to 900-MHz radio frequency radiation at levels comparable to cell phone exposure and found their movement speed increased by 50% compared to temperature effects alone. More significantly, the cells stopped following chemical signals they normally track to fight infection, instead moving at right angles to those signals. The calculated temperature change from the RF exposure was negligible, indicating a non-thermal biological effect.
Unknown authors · 2008
Researchers exposed human immune cells (neutrophils) to 900-MHz RF radiation at extremely low power levels in laboratory conditions. The RF exposure increased cell movement speed by 50% compared to temperature effects alone and dramatically altered the cells' direction of movement away from their normal chemical tracking pattern. These changes occurred at power levels producing less than one-millionth of a degree of heating.
Unknown authors · 2008
Researchers exposed human immune cells called neutrophils to 900-MHz radio frequency fields at levels comparable to cell phone exposure. The cells moved 50% faster than normal and changed direction, moving perpendicular to their intended path rather than toward chemical signals they normally follow. These effects occurred without measurable heating, suggesting non-thermal biological impacts on immune function.
Unknown authors · 2008
Researchers studied 46 spot welders exposed to extremely low frequency magnetic fields (50 Hz, 8.8-84 microTesla) and found their red blood cells had significantly reduced antioxidant enzyme activity compared to unexposed workers. The study showed a 22% decrease in superoxide dismutase and 12.3% decrease in glutathione peroxidase, suggesting these magnetic fields act as oxidative stressors even at recommended exposure levels.
Unknown authors · 2008
Researchers studied 46 spot welders exposed to extremely low frequency magnetic fields (50 Hz, 8.8-84 microTesla) and found their red blood cells had significantly reduced antioxidant enzyme activity compared to unexposed workers. The stronger the magnetic field exposure, the greater the reduction in protective enzymes that normally defend cells against oxidative damage.
Sanchez S et al. · 2008
Researchers investigated heat shock protein expression in hairless rat skin exposed to GSM-900 and GSM-1800 signals. They studied Hsc70, Hsp25, and Hsp70 using immunolabeling of epidermal skin slices. Single exposures were 2 hours at 0 and 5 W/kg; repeated exposures were 2 hours per day, 5 days per week for 12 weeks at 0, 2.5, and 5 W/kg. Neither single nor repeated exposures altered HSP expression regardless of GSM signal or SAR.
Dawe AS et al. · 2008
Researchers exposed a transgenic strain of the nematode C. elegans to radiofrequency fields at 1.8 GHz and a specific absorption rate of approximately 1.8 W/kg. For both continuous wave and Talk-pulsed exposures lasting 2.5 hours, there was no indication that RF exposure could induce reporter expression above sham control levels. When background reporter expression was moderately elevated in sham controls, the researchers found some evidence that reporter expression may be reduced by approximately 15% following exposure to either Talk-pulsed or CW RF fields.
Unknown authors · 2008
Researchers used a rat model of chemically induced B acute lymphoblastic leukemia to test effects of 50 Hz magnetic fields with and without harmonics. The experiment included 280 rats and compared body weight, survival time, bone marrow blast cells, cumulative leukemia incidence, and leukemia type between exposed and unexposed groups. No significant differences were found for any parameter (p > 0.05). Results did not support the hypothesis that ELF-MFs, with or without harmonics, affect the development of B acute lymphoblastic leukemia in children.
Unknown authors · 2008
Researchers exposed groups of 108 DMBA-treated Fischer 344 rats to a 100 muT, 50 Hz magnetic field or sham exposure for 26 weeks. MF exposure significantly facilitated mammary tumorigenesis. The incidence of histologically verified adenocarcinomas was increased by 45% (P = 0.0095). The most pronounced effect on tumor incidence was seen in the cranial inguinal complexes.
Unknown authors · 2008
Researchers exposed 280 rats to 50 Hz magnetic fields (100 microT) while chemically inducing leukemia to test whether power line frequencies promote cancer development. The study found no differences in survival, leukemia incidence, or disease progression between exposed and unexposed animals. This suggests that power line frequency magnetic fields do not accelerate leukemia development in this animal model.
Unknown authors · 2008
Researchers exposed Fischer 344 rats to power line frequency magnetic fields (100 µT at 50 Hz) for 26 weeks after treating them with a cancer-causing chemical. The magnetic field exposure increased breast cancer rates by 45% compared to unexposed rats. This study suggests that common household and power grid magnetic fields may promote breast cancer development.
Pavicic I, Trosic I · 2008
Researchers exposed V79 cells to continuous wave frequencies of 864 MHz and 935 MHz for 1, 2, or 3 hours. Growth was significantly increased after two- and three-hour exposures to 864 MHz and after three-hour exposure to 935 MHz, measured 72 hours after irradiation. Colony-forming ability and cell viability did not significantly differ from control cells. The two fields showed similar effects on growth, colony-forming ability, and viability, with impact being time-dependent.
Inoue S, Motoda H, Koike Y, Kawamura K, Hiragami F, Kano Y. · 2008
Exposure to 2.45 GHz microwave irradiation at 200 W increased neurite outgrowth frequency about 10-fold compared to non-irradiated controls. The increase was prevented by adding a p38 MAPK inhibitor. Microwave treatment did not cause toxicity, unlike heat shock at 45°C.
Türközer Z, Güler G, Seyhan N. · 2008
Researchers aimed to evaluate the effects of varied 50 Hz electric field exposure on lipid peroxidation and antioxidant enzyme activities in guinea pig brain homogenates. Guinea pigs were exposed to electric fields ranging from 2 to 5 kV/m for three days, eight hours per day, in both vertical and horizontal directions. No statistically significant differences were found between exposed and sham groups in lipid peroxidation levels or enzyme activities at any field strength or direction. Comparisons between vertical and horizontal exposure directions also showed no significant differences.
Türközer Z, Güler G, Seyhan N · 2008
Researchers exposed guinea pigs to powerful electric fields (the kind found near high-voltage power lines) for 8 hours daily over three days to see if it would damage brain tissue through oxidative stress. They found no statistically significant effects on brain cell damage markers or antioxidant defenses, even at the highest exposure levels tested. While this suggests these particular electric field exposures may not cause measurable brain oxidative damage in the short term, the researchers noted some non-significant trends that warrant further investigation.
Prisco MG et al. · 2008
Johansson A et al. · 2008
Fifteen subjects with atopic dermatitis and 15 matched controls were exposed for 30 min to a 900 MHz GSM mobile phone-like RF field at 1 W/kg. Blood samples were taken before and after exposure to measure serum levels of substance P (SP), TNF R1, and brain derived neurotrophic factor (BDNF). At baseline, the atopic dermatitis group had significantly higher serum TNF R1 and significantly lower BDNF than controls, while SP did not differ. No effects of RF exposure were found on any of the measured substances. Symptom reports were too few to evaluate a possible correlation with exposure.
Moisescu MG, Leveque P, Bertrand JR, Kovacs E, Mir LM · 2008
Researchers designed a device for continuous microscopic observation of cells exposed to modulated EMF similar to mobile phone signals. The system allowed follow-up of cell progression into mitosis under controlled temperature and CO2 environment. Cells exposed to 900 MHz modulated EMF for 1 hour at 30 degrees C and 2.2 W/kg showed increased endocytosis rate but no alteration in mitosis progression or duration. The exposure system was validated by cell endocytosis measurements.
Unknown authors · 2008
Researchers exposed murine L929 fibroblasts to 872 MHz continuous wave or pulse modulated RF radiation at 5 W/kg. They measured ornithine decarboxylase activity after 1- and 24-hour exposures, proliferation during 48 hours after 24-hour exposure, and caspase-3 activity after 1-hour exposure. The cells responded to fresh medium and serum deprivation, but no consistent effects of RF radiation were found. One statistically significant difference in ODC activity (p=0.03) was observed but considered a chance finding due to multiple comparisons and lack of support from other data. The results did not support effects on the endpoints studied, and stressed or stimulated cells were not more sensitive than normal cells to RF radiation.
Unknown authors · 2008
Finnish researchers exposed mouse fibroblasts to 872 MHz radiofrequency radiation at 5 W/kg to test whether cell stress affects EMF sensitivity. They measured cell growth, death signals, and enzyme activity under normal, stimulated, and stressed conditions. No consistent biological effects were found from the RF exposure, regardless of the cells' physiological state.
Ross ML, Koren SA, Persinger MA. · 2008
Researchers tested whether a weak magnetic field pulsed over the left prefrontal brain region at the moment of accepting or refuting a statement could increase the likelihood of later accepting a false statement as true. Fifty men and women were each exposed to one of four magnetic field conditions, or a sham field, over the left prefrontal region above the eyebrow. Groups that received the burst-firing or 25 Hz pulsed fields during the refutation process accepted about twice the number of false statements as true compared to those in the 50 Hz or sham-field conditions. The treatments did not significantly affect the numbers of true statements accepted as false.
Lee JJ et al. · 2008
NIH3T3 mouse fibroblasts were exposed to 849 MHz RF radiation at average SAR values of 2 or 10 W/kg for either 1 hour or 1 hour per day for 3 days. Cellular invasion and migration were assessed using in vitro Matrigel invasion and Transwell migration assays. Cell cycle distribution was analyzed at 24 and 48 hours after exposure by flow cytometry. The study found no detectable effects on cell cycle distribution, cellular migration, or invasion at the tested SAR values.
