3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,644 studies in Brain & Nervous System

The genotoxic effect of radiofrequency waves on mouse brain.

Karaca E et al. · 2012

Turkish researchers exposed mouse brain cells to radiofrequency radiation at 10.715 GHz (similar to cell phone frequencies) for 6 hours daily over 3 days. They found an 11-fold increase in DNA damage markers and significant changes in gene expression related to cell death. This suggests that RF radiation at levels comparable to wireless devices can directly damage brain cell DNA and disrupt normal cellular functions.

Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation

Fragopoulou AF et al. · 2012

Researchers exposed mice to mobile phone and cordless phone radiation for 8 months and examined brain tissue for protein changes. They found that both radiation sources significantly altered 143 different proteins in brain regions, including proteins involved in brain function, stress response, and cell structure. These protein changes may explain symptoms like headaches, memory problems, and sleep disturbances reported by people with long-term phone use.

Effect of 900 MHz radio frequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the brain

Dasdag S, Akdag MZ, Kizil G, Kizil M, Cakir DU, Yokus B · 2012

Researchers exposed rats to cell phone radiation (900 MHz) for 2 hours daily over 10 months and examined their brains for signs of damage. They found significantly increased protein carbonyl levels, which indicates protein damage from oxidative stress. This suggests that long-term cell phone radiation exposure may harm brain proteins, potentially contributing to neurodegenerative processes.

Modulation of heat shock protein response in SH-SY5Y by mobile phone microwaves

Calabrò E et al. · 2012

Italian researchers exposed human brain cells to cell phone radiation at 1800 MHz for 2-4 hours and measured stress protein responses. They found that the radiation triggered cellular stress responses in the neurons, specifically decreasing one protective protein (Hsp20) and increasing another (Hsp70) after longer exposure. This suggests that cell phone radiation can activate stress pathways in brain cells even at levels considered safe by current standards.

Effects of 900 MHz radiofrequency on corticosterone, emotional memory and neuroinflammation in middle-aged rats

Bouji M, Lecomte A, Hode Y, de Seze R, Villégier AS · 2012

French researchers exposed young and middle-aged rats to 15 minutes of cell phone radiation (900 MHz) at high levels to study brain and stress responses. They found that middle-aged rats showed increased brain inflammation and enhanced emotional memory, while young rats had elevated stress hormone levels. The study reveals that age affects how the brain responds to radiofrequency exposure, with different vulnerabilities at different life stages.

Suppressive effect of electromagnetic field on analgesic activity of tramadol in rats

Bodera P et al. · 2012

Polish researchers exposed rats to cell phone-frequency electromagnetic fields (1500 MHz and 1800 MHz) for 15 minutes and tested how well the painkiller tramadol worked afterward. While the EMF exposure alone didn't change pain sensitivity, it significantly reduced tramadol's pain-relieving effects when the two were combined. This suggests that EMF exposure from devices like cell phones might interfere with how certain medications work in the body.

Fetal Radiofrequency Radiation Exposure From 800-1900 Mhz-Rated Cellular Telephones Affects Neurodevelopment and Behavior in Mice

Aldad TS, Gan G, Gao XB, Taylor HS · 2012

Researchers exposed pregnant mice to radiofrequency radiation from cell phones (at levels similar to human exposure) throughout pregnancy and then tested the offspring's behavior and brain function. The exposed mice showed hyperactivity and memory problems as adults, along with measurable changes in brain cell communication in the prefrontal cortex. This study provides the first direct experimental evidence that prenatal cell phone radiation exposure can alter brain development and behavior.

Brain & Nervous SystemNo Effects Found

Effect of exposure to 1,800 MHz electromagnetic fields on heat shock proteins and glial cells in the brain of developing rats.

Watilliaux A, Edeline JM, Lévêque P, Jay TM, Mallat M. · 2011

French researchers exposed developing rats to cell phone radiation (1800 MHz) for 2 hours at SAR levels of 1.7-2.5 W/kg to see if it would trigger stress responses or damage in brain cells. They found no evidence of cellular stress, inflammation, or damage to the glial cells that support brain function. This suggests that brief exposures to cell phone radiation at these levels may not cause immediate harm to developing brain tissue.

Brain & Nervous SystemNo Effects Found

Republished review: systematic review and meta-analysis of psychomotor effects of mobile phone electromagnetic fields.

Valentini E, Ferrara M, Presaghi F, De Gennaro L, Curcio G. · 2011

Italian researchers analyzed 24 studies to determine if mobile phone radiation affects thinking skills and reaction times. Their meta-analysis found no significant cognitive or psychomotor effects from mobile phone-like electromagnetic fields. However, they discovered that studies funded by the wireless industry were more likely to show no effects, while studies with mixed funding sources sometimes found small impacts on working memory tasks.

Brain & Nervous SystemNo Effects Found

Effects of exposure to electromagnetic fields emitted by GSM 900 and WCDMA mobile phones on cognitive function in young male subjects.

Sauter C et al. · 2011

German researchers exposed 30 young men to mobile phone signals (GSM 900 and WCDMA) for over 7 hours to test effects on cognitive function including attention and working memory. While some minor changes appeared in vigilance tests, these effects disappeared when researchers properly accounted for statistical testing and time-of-day variations. The study found no evidence that extended mobile phone radiation exposure impairs cognitive performance.

DNA & Genetic DamageNo Effects Found

Analysis of gene expression in a human-derived glial cell line exposed to 2.45 GHz continuous radiofrequency electromagnetic fields.

Sakurai T et al. · 2011

Japanese researchers exposed human brain cells (glial cells) to 2.45 GHz radiofrequency radiation at various power levels for up to 24 hours and examined whether this changed gene activity. Using advanced genetic analysis techniques, they found no significant changes in how genes were expressed in the exposed cells compared to unexposed controls. This suggests that RF radiation at these levels did not trigger detectable genetic responses in this type of brain cell.

Brain & Nervous SystemNo Effects Found

Thermal effects of mobile phone RF fields on children: a provocation study.

Lindholm H et al. · 2011

Finnish researchers exposed 26 teenage boys (ages 14-15) to GSM 900 mobile phone radiation for 15 minutes to measure thermal effects and blood flow changes in their heads. They found no significant increases in ear canal temperature, no changes in local brain blood flow, and no interference with the autonomic nervous system. This controlled study suggests that short-term mobile phone exposure at typical power levels doesn't produce measurable thermal effects in adolescents' heads.

Cancer & TumorsNo Effects Found

Lymphoma development of simultaneously combined exposure to two radiofrequency signals in AKR/J mice.

Lee HJ et al. · 2011

Researchers exposed mice genetically prone to lymphoma to combined cell phone signals (CDMA and WCDMA) for 45 minutes daily over 42 weeks at high exposure levels (4.0 W/kg total). The study found no difference in lymphoma development between exposed and unexposed mice, though there was an inconsistent pattern of brain metastasis in some exposed animals.

Brain & Nervous SystemNo Effects Found

Effect of chronic exposure to cellular telephone electromagnetic fields on hearing in rats.

Kayabasoglu G et al. · 2011

Turkish researchers exposed rats to cell phone electromagnetic fields for 6 hours daily over 30 days to test whether EMF radiation damages hearing. Using sensitive hearing tests that measure inner ear function, they found no changes in hearing ability in either newborn or adult rats after the month-long exposure. This suggests that typical cell phone EMF exposure may not directly harm the delicate structures of the inner ear that are responsible for hearing.

Cancer & TumorsNo Effects Found

Use of mobile phones and risk of brain tumours: update of Danish cohort study.

Frei P et al. · 2011

Danish researchers tracked nearly 60,000 mobile phone subscribers for up to 18 years to see if they developed brain tumors at higher rates than non-subscribers. They found no increased risk of brain tumors, including gliomas and meningiomas, even among people who had used phones for 13 or more years. The study provides reassuring evidence that mobile phone use doesn't appear to cause brain cancer.

Brain & Nervous SystemNo Effects Found

Prenatal cell phone use and developmental milestone delays among infants.

Divan HA, Kheifets L, Olsen J. · 2011

Researchers tracked over 41,000 Danish mothers and their children to see if cell phone use during pregnancy affected early childhood development milestones. They found no connection between prenatal cell phone exposure and delays in cognitive, language, or motor development at 6 and 18 months of age. This large study suggests that typical cell phone use during pregnancy doesn't appear to harm early brain development in infants.

Cancer & TumorsNo Effects Found

Mobile phone use and brain tumors in children and adolescents: a multicenter case-control study.

Aydin D et al. · 2011

Researchers studied whether mobile phone use increases brain tumor risk in children and teenagers by comparing 352 young brain tumor patients with 646 healthy controls across four European countries. They found no statistically significant increase in brain tumor risk among regular mobile phone users, and importantly, no relationship between the amount of phone use and tumor development. The study suggests that mobile phone use is not causing brain tumors in young people.

Brain & Nervous SystemNo Effects Found

Lack of effect of 50-Hz magnetic field exposure on the binding affinity of serotonin for the 5-HT 1B receptor subtype.

Masuda H et al. · 2011

Researchers exposed rat brain tissue and human cells to 50-Hz magnetic fields at 1 milliTesla (similar to levels near power lines) to see if this affected serotonin receptors, which are important for brain function and mood. They found no changes in how serotonin bound to these receptors or in the cellular responses that follow. This suggests that magnetic field exposure at this level doesn't interfere with this particular brain signaling pathway.

Brain & Nervous SystemNo Effects Found

Microstructure abnormalities in adolescents with internet addiction disorder

Yuan K et al. · 2011

Researchers used brain imaging to study 18 teenagers with internet addiction disorder, comparing their brain structure to healthy controls. They found significant changes in brain gray matter volume and white matter integrity in areas responsible for decision-making, impulse control, and emotional regulation. The severity of these brain changes correlated directly with how long the teenagers had been addicted to the internet.

Brain & Nervous SystemNo Effects Found

Effect of exposure to 1,800 MHz electromagnetic fields on heat shock proteins and glial cells in the brain of developing rats.

Watilliaux A, Edeline JM, Lévêque P, Jay TM, Mallat M · 2011

Researchers exposed developing rat brains to cell phone radiation (1,800 MHz) for 2 hours at levels similar to what phones emit near your head. They looked for signs of cellular stress and brain cell damage one day later by measuring stress proteins and examining brain tissue. The study found no evidence of cellular stress or damage to developing brain cells at these exposure levels.

Brain & Nervous SystemNo Effects Found1,197 citations

Mobile phone use and stress, sleep disturbances, and symptoms of depression among young adults - a prospective cohort study

Thomée S, Härenstam A, Hagberg M · 2011

Swedish researchers followed over 4,000 young adults for one year to examine whether mobile phone use patterns affect mental health. They found that heavy phone users were more likely to experience stress, sleep problems, and depression symptoms, with the strongest effects among those who felt pressured to always be accessible. The study suggests that how we use our phones psychologically matters as much as how often we use them.

Brain & Nervous SystemNo Effects Found

Effects of exposure to electromagnetic fields emitted by GSM 900 and WCDMA mobile phones on cognitive function in young male subjects

Sauter C et al. · 2011

German researchers exposed 30 young men to mobile phone radiation (900 MHz and 1,966 MHz) for over 7 hours daily for three days, then tested their cognitive abilities including attention, memory, and vigilance. After accounting for natural daily variations in mental performance, they found no significant effects from either type of phone radiation on any cognitive function tested.

DNA & Genetic DamageNo Effects Found

Analysis of gene expression in a human-derived glial cell line exposed to 2.45 GHz continuous radiofrequency electromagnetic fields

Sakurai T et al. · 2011

Researchers exposed human brain cells (glial cells) to 2.45 GHz radiofrequency radiation at power levels up to 10 times higher than current safety limits for up to 24 hours. They used advanced genetic analysis to look for changes in how genes were expressed, but found no significant alterations. This suggests that even at high exposure levels, this type of RF radiation may not directly damage the genetic machinery of brain cells.

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