3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 481 studies in DNA & Genetic Damage

Radiofrequency electromagnetic fields; male infertility and sex ratio of offspring.

Baste V, Riise T, Moen BE. · 2008

Norwegian researchers studied over 10,000 military personnel to examine whether exposure to radiofrequency electromagnetic fields affects male fertility and the sex ratio of their children. They found that men with higher RF exposure were significantly more likely to experience infertility, with those working closest to high-frequency antennas showing an 86% increased risk. Additionally, fathers with greater RF exposure were more likely to have daughters than sons.

Combinative exposure effect of radio frequency signals from CDMA mobile phones and aphidicolin on DNA integrity.

Tiwari R et al. · 2008

Researchers exposed blood samples from six healthy men to radio frequency signals from CDMA mobile phones for one hour, then tested for DNA damage using a technique called the comet assay. They found that while RF exposure alone didn't cause significant DNA damage, it did enhance DNA breaks when combined with a chemical that interferes with DNA repair. This suggests that mobile phone radiation may cause DNA damage that cells can normally repair, but problems could arise when repair mechanisms are compromised.

In vitro assessment of clastogenicity of mobile-phone radiation (835 MHz) using the alkaline comet assay and chromosomal aberration test.

Kim JY et al. · 2008

Korean researchers exposed mammalian cells to 835-MHz radiofrequency radiation (the frequency used in Korean CDMA cell phones) to test whether it causes genetic damage. While the radiation alone didn't directly damage DNA or chromosomes, it amplified the genetic damage when cells were also exposed to known cancer-causing chemicals. The researchers concluded they couldn't rule out increased genetic damage risk from this cell phone frequency.

A pulsing electric field (PEF) increases human chondrocyte proliferation through a transduction pathway involving nitric oxide signaling.

Fitzsimmons RJ, Gordon SL, Kronberg J, Ganey T, Pilla AA. · 2008

Researchers exposed human cartilage cells (chondrocytes) to pulsed electric fields for 30 minutes and found the cells multiplied 150% more than untreated cells after 72 hours. The study identified the biological pathway responsible: the electric fields triggered calcium signaling, which produced nitric oxide, which ultimately stimulated cell growth. This demonstrates that electric fields can directly influence cellular processes through well-understood biochemical mechanisms.

Evaluation of genotoxic effects in human leukocytes after in vitro exposure to 1950 MHz UMTS radiofrequency field.

Zeni O et al. · 2008

Researchers exposed white blood cells from six healthy people to 3G cell phone radiation (1950 MHz UMTS) at levels similar to those from phones held against the head (2.2 W/kg SAR). They used intermittent exposures over 24 to 68 hours and tested for DNA damage using two sensitive laboratory methods. The study found no evidence of genetic damage or changes in how cells divide and grow.

[Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields]

Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. · 2008

Chinese researchers exposed human eye lens cells to cell phone radiation (1800 MHz) and found it caused DNA damage and increased harmful free radicals. However, when they added electromagnetic 'noise' fields alongside the phone radiation, this protective interference blocked the cellular damage. The study suggests that certain electromagnetic patterns might counteract the harmful effects of mobile phone radiation on eye cells.

Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes.

Schwarz C et al. · 2008

Researchers exposed human cells to 3G mobile phone radiation (UMTS at 1,950 MHz) at levels well below safety limits to test for DNA damage. They found that certain cells called fibroblasts showed significant genetic damage after exposure, while immune cells called lymphocytes were unaffected. This suggests that 3G radiation can cause DNA damage in some human cell types even at supposedly safe exposure levels.

Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex.

Nittby H et al. · 2008

Researchers exposed rats to cell phone radiation at 1,800 MHz for 6 hours and found significant changes in brain gene activity. The genetic alterations affected genes controlling cell membranes and cellular communication in the cortex and hippocampus, the same brain regions where previous studies documented blood-brain barrier damage.

Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours.

Mazor R et al. · 2008

Researchers exposed human blood cells to 800 MHz radiofrequency radiation (similar to cell phone frequencies) for 72 hours at power levels close to current safety limits. They found significant increases in chromosome damage called aneuploidy, where cells gained or lost whole chromosomes. Importantly, this damage occurred even when temperature was carefully controlled, suggesting the radiation itself caused genetic harm through non-thermal mechanisms.

[Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields].

Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. · 2008

Researchers exposed human eye lens cells to cell phone radiation at 4 watts per kilogram for 24 hours and found it caused significant DNA damage and increased harmful molecules called reactive oxygen species. However, when they added electromagnetic 'noise' (random magnetic fields) during the exposure, it completely blocked these harmful effects. This suggests that certain types of electromagnetic interference might actually protect cells from radiation damage.

Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP)sites in A172 cells.

Koyama S, Sakurai T, Nakahara T, Miyakoshi J · 2008

Researchers exposed human brain cancer cells to 60 Hz magnetic fields (the same frequency as household electricity) to see if it would increase DNA damage. They found that while the magnetic fields alone didn't damage DNA, they significantly amplified the DNA damage caused by toxic chemicals. This suggests that common power-frequency magnetic fields may make cells more vulnerable to other sources of genetic damage.

Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex.

Nittby H et al. · 2008

Swedish researchers exposed rats to cell phone radiation at 1,800 MHz for six hours and found significant changes in brain gene expression. The radiation altered genes controlling cell membranes and signal transmission in memory-critical brain regions, occurring at levels similar to extended human cell phone use.

Effect of 1.8 GHz radiofrequency electromagnetic fields on gene expression of rat neurons

Zhang SZ, Yao GD, Lu DQ, Chiang H, Xu ZP. · 2008

Chinese researchers exposed rat brain neurons to 1.8 GHz radiofrequency radiation (the same frequency used in cell phones) at 2 W/kg for up to 24 hours. They found that 34 genes changed their expression patterns, including genes involved in brain cell structure and signaling. The changes were more pronounced with intermittent exposure than continuous exposure, suggesting that the pattern of EMF exposure matters for biological effects.

Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells.

Yao K, Wu W, Wang K, Ni S, Ye P, Yu Y, Ye J, Sun L. · 2008

Researchers exposed human eye lens cells to 1.8 GHz radiofrequency radiation (the frequency used by GSM cell phones) at power levels of 1-4 watts per kilogram for 2 hours. They found that higher exposure levels caused DNA damage and increased harmful molecules called reactive oxygen species in the cells. Interestingly, when they added electromagnetic 'noise' to the radiation, it prevented these cellular damage effects.

Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields.

Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. · 2008

Researchers exposed human eye lens cells to cell phone radiation at levels four times higher than safety limits and found it caused DNA damage and increased harmful reactive oxygen species (molecules that damage cells). However, when they simultaneously exposed the cells to electromagnetic noise fields, this completely blocked the DNA damage and cellular harm from the phone radiation.

Radiofrequency electromagnetic fields (UMTS, 1,950 MHz) induce genotoxic effects in vitro in human fibroblasts but not in lymphocytes.

Schwarz C et al. · 2008

German researchers exposed human cells to cell phone radiation (UMTS, 1,950 MHz) at levels well below safety limits to test for DNA damage. They found that skin cells (fibroblasts) showed significant genetic damage at extremely low exposure levels - as little as 0.05 W/kg, which is 40 times lower than the current safety limit. However, immune cells (lymphocytes) showed no damage, suggesting different cell types respond differently to radiofrequency radiation.

Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex.

Nittby H et al. · 2008

Swedish researchers exposed rats to cell phone radiation at 1,800 MHz for 6 hours and analyzed gene activity in brain regions critical for memory and thinking. The radiation significantly altered the expression of hundreds of genes, particularly those involved in cell membrane functions and cellular communication. This suggests that even brief exposure to mobile phone radiation can trigger measurable biological changes in brain tissue at the genetic level.

Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours.

Mazor R et al. · 2008

Researchers exposed human blood cells to 800 MHz radiofrequency radiation (similar to cell phone frequencies) for 72 hours at levels close to current safety limits. They found significant increases in chromosome abnormalities called aneuploidy, where cells had the wrong number of chromosomes. This type of genetic damage can contribute to cancer development and other health problems.

Effects of modulated microwave radiation at cellular telephone frequency (1.95 GHz) on X-ray-induced chromosome aberrations in human lymphocytes in vitro.

Manti L et al. · 2008

Researchers exposed human blood cells to cell phone radiation, then X-rays, to test DNA damage effects. While radiation didn't increase damaged cells overall, it increased chromosome damage within affected cells by a small but significant amount, suggesting interference with DNA repair processes.

DNA & Genetic DamageNo Effects Found101 citations

Genotoxic effects of exposure to radiofrequencyelectromagnetic fields (RF-EMF) in cultured mammalian cells are not independently reproducible.

Speit G, Schütz P, Hoffmann H. · 2007

German researchers attempted to replicate the controversial REFLEX study findings that showed cell phone radiation (1800 MHz) could damage DNA in human cells. Using identical equipment, cells, and exposure conditions, they found no DNA damage whatsoever. This directly contradicted the original REFLEX results that had suggested radiofrequency radiation at levels similar to cell phones could be genotoxic (DNA-damaging).

DNA & Genetic DamageNo Effects Found

Micronucleus frequency in erythrocytes of mice after long-term exposure to radiofrequency radiation.

Juutilainen J, Heikkinen P, Soikkeli H, Mäki-Paakkanen J. · 2007

Finnish researchers exposed mice to cell phone radiation for over a year to test whether it damages DNA by looking for micronuclei (broken chromosome fragments) in blood cells. They found no DNA damage from radiofrequency exposure at levels similar to what humans experience from mobile phones. This was true across different phone technologies (analog and digital), exposure durations (52-78 weeks), and mouse strains.

Cellular EffectsNo Effects Found

Evaluating the biological effects of intermittent 1.9 GHz pulse-modulated radiofrequency fields in a series of human-derived cell lines.

Chauhan V et al. · 2007

Canadian government researchers exposed three types of human cells to 1.9 GHz radiofrequency radiation (similar to cell phone signals) for 6 hours at power levels up to 10 W/kg. They measured multiple indicators of cellular stress including cell death, DNA damage, immune responses, and cell cycle disruption. The study found no detectable biological effects from the RF exposure at any power level tested.

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