Jin YB, Lee HJ, Seon Lee J, Pack JK, Kim N, Lee YS. · 2011
Researchers exposed two groups of 40 Sprague-Dawley rats to CDMA and WCDMA radiofrequency fields simultaneously at 2.0 W/kg each for 45 minutes per day, five days a week, for one year. No significant alteration in body weight was observed with the combined exposure. Total tumour incidence did not differ between exposed and sham-exposed animals. Most exposed rats showed no significant changes in urinalysis, haematology, blood biochemistry, or histopathology. However, some altered parameters in complete blood count and serum chemistry were seen in exposed rats.
Frei P et al. · 2011
Researchers investigated the risk of central nervous system tumours among Danish mobile phone subscribers. The cohort included 58 403 subscription holders with 3.8 million person years of follow-up from 1990-2007, during which 10 729 tumour cases occurred. The overall risk was close to unity for both men and women. For those with 13 or more years of subscription, incidence rate ratios were 1.03 in men and 0.91 in women. No dose-response relation was found by years of use or tumour location near the handset.
Aydin D et al. · 2011
The CEFALO study included children and adolescents aged 7–19 years diagnosed with brain tumors between 2004 and 2008 in Denmark, Sweden, Norway, and Switzerland. Researchers interviewed 352 case patients and 646 control subjects matched by age, sex, and geographical region. Regular mobile phone users did not have a statistically significant increase in brain tumor risk compared with nonusers. No increased risk was found for brain areas receiving the highest exposure, and no exposure–response relationship was observed.
Yakymenko I, Sidorik E, Kyrylenko S, Chekhun V. · 2011
Mortazavi SMJ et al. · 2011
Eighty male rats were randomly divided into six groups of 13 to 15 animals. The first five groups received microwave exposure, microwave plus flaxseed oil, flaxseed continued after irradiation, flaxseed alone, or olive oil before a whole-body gamma-ray dose of 8 Gy on day 5. At 30 days, microwave-pretreated rats showed 100% survival, while control rats had 53.3% survival, and the other groups had survival fractions of 69.2%, 92.3%, 46.1%, and 61.5%.
Levis AG et al. · 2011
Hardell L, Carlberg M, Hansson Mild K. · 2011
Researchers pooled two case-control studies of living patients and one case-control study of deceased patients with malignant brain tumours diagnosed from 1997 to 2003. They interviewed cases, controls, and relatives of deceased subjects using a structured questionnaire. Replies were obtained for 1,251 cases and 2,438 controls. The risk of glioma increased with latency period and cumulative hours of mobile and cordless phone use. For astrocytoma, the most common glioma, the odds ratio was 2.7 for mobile phone use with more than ten years latency and 4.9 for first mobile phone use before age 20.
Hardell L, Carlberg M, Hansson Mild K, Eriksson M. · 2011
Costa FP et al. · 2011
A single-group, open-label, phase I/II study assessed the safety and effectiveness of intrabuccal amplitude-modulated electromagnetic fields at HCC-specific frequencies in 41 patients with advanced hepatocellular carcinoma and limited therapeutic options. Patients received three daily 60-minute outpatient treatments until disease progression or death. Treatment was well tolerated with no NCI grade 2, 3, or 4 toxicities. Fourteen patients (34.1%) had stable disease for more than 6 months, median progression-free survival was 4.4 months (95% CI 2.1–5.3), median overall survival was 6.7 months (95% CI 3.0–10.2), and there were three partial and one near complete responses.
Aydin D et al. · 2011
Researchers performed simulations using real data from the CEFALO case–control study to assess how recall errors and selection bias affect odds ratios for mobile phone use and brain tumor risk in children and adolescents. In a validation study, cases overestimated their number of calls by 9% on average and controls by 34%, while cases overestimated call duration by 52% and controls by 163%. Participation rates were 83% for cases and 71% for controls, and the combined impact of recall error and selection bias on estimated odds ratios was complex across various scenarios.
Dode AC et al. · 2011
Researchers examined a spatial correlation between cellular base station clusters and deaths by neoplasia in Belo Horizonte, Brazil, from 1996 to 2006. The study used a descriptive ecological-epidemiological approach with georeferencing, drawing on death records, base station registrations, and census data. Between 1996 and 2006, 7191 deaths by neoplasia occurred, and within 500 m of a base station the mortality rate was 34.76 per 10,000 inhabitants, with a decrease in deaths observed outside that area.
Martino CF, Castello PR · 2011
Researchers studied how suppressing the Earth's magnetic field to between 0.2 µT and 2 µT affected hydrogen peroxide production in several cell types. The cell types tested were a human fibrosarcoma cancer cell line, a pancreatic cancer cell line, and bovine pulmonary artery endothelial cells. Reducing the Earth's magnetic field suppressed hydrogen peroxide production in the cancer cells and the endothelial cells. Adding catalase and a superoxide dismutase mimetic called MnTBAP inhibited the magnetic field effect.
Haggerty K. 2010 · 2010
Unknown authors · 2010
Unknown authors · 2010
K562 cells were exposed to 8.8 mT static magnetic fields with or without cisplatin. The magnetic fields enhanced cisplatin's killing effect, reducing the efficient killing concentration from 20 to 10 microg/mL. Cells treated with both magnetic fields and cisplatin showed S-phase cell cycle arrest. DNA became thicker with magnetic field exposure alone, while DNA breakage increased more with the combined treatment than with cisplatin alone.
Unknown authors · 2010
Unknown authors · 2010
A positive association was found between high-level exposure above 0.4 microT and the risk of brain tumors. This association could not be explained solely by confounding factors or selection bias.
Unknown authors · 2010
Researchers conducted a population-based case-control study in Germany to investigate whether preconceptional parental occupational exposure to extremely low frequency magnetic fields increased childhood cancer risk. Parental occupational history was recorded using questionnaires and telephone interviews, and preconceptional magnetic field exposure was estimated via a job-exposure matrix. The analysis included 2,382 controls and 2,049 cases, comprising 846 acute leukemia, 159 non-Hodgkin's lymphoma, 444 central nervous system tumors, and 600 other solid tumors. Frequency-matched conditional logistic regression models showed no increased cancer risks for paternal exposure above 0.2 microT, no risk increase above 1 microT, and maternal exposure was also not associated with increased risks.
Unknown authors · 2010
The meta-analysis included 15 studies published from 2000 to 2009 with 24,338 cases and 60,628 controls. The overall analysis showed no significant association with an odds ratio of 0.988 and a 95% confidence interval of 0.898 to 1.088. Subgroup analyses by exposure modes, menopausal status, and estrogen receptor status also found no significant association.
Unknown authors · 2010
They identified 64 cases of newly-diagnosed hematological malignancies in children under 14 from 1986 to 2007 and sampled four matched controls per case. The relative risk of leukemia for residence in areas with exposure ≥0.1 microTesla was 3.2 (6.7 after adjusting for socioeconomic status), but the estimate was statistically unstable with a 95% confidence interval of 0.4 to 23.4. The relative risk for acute lymphoblastic leukemia was 5.3 (95% CI 0.7-43.5), while no increased risk was found for other hematological malignancies.
Unknown authors · 2010
Unknown authors · 2010
Researchers conducted a case-control study with 300 children with acute lymphoblastic leukemia and 300 matched controls. Cases lived significantly closer to power lines than controls (P<0.001). Living within 600 meters of the nearest power line was associated with an odds ratio of 2.61 (95% CI: 1.73 to 3.94) compared to living farther away. Odds ratios were 9.93 for 123 kV lines, 10.78 for 230 kV lines, and 2.98 for 400 kV lines. Odds of leukemia decreased by a factor of 0.61 for every 600 meters of distance from the nearest power line.
Unknown authors · 2010
Early studies tended toward a consistent association between risks for leukemia and brain cancer and residential proximity to power lines having high wire configuration. More recent studies using improved exposure measurement methods have produced inconsistent results, with some suggesting increased risk and others not. Occupational exposures suggested increased risk for leukemia and to a lesser extent brain cancer and Non-Hodgkin lymphoma. Studies of residential exposures and cancer in adults generally suggested no effect. Laboratory work has been unable to demonstrate a biological mechanism that might explain the epidemiological findings.
Unknown authors · 2010
Researchers tested alternative dose-response relationships quantitatively using five exposure data sets and three epidemiological data sets. Threshold dose-response relationships performed only moderately. Linear relationships were generally even poorer. The fit was improved by adding quadratic terms or performing non-linear regression.
Unknown authors · 2010
The systematic review analyzed publications from 1979 to 2008 on the association between environmental non-ionizing radiation exposure and childhood leukemia risk. The review concluded that studies have not convincingly confirmed or ruled out an association. Discrepancies among study conclusions may be influenced by confounding factors, selection bias, and misclassification. The authors state an urgent need to reconsider exposure limits for low frequency and static magnetic fields based on combined experimental and epidemiological research.
