Odacı E et al. · 2013
Researchers exposed pregnant rats to 900 MHz electromagnetic fields for one hour daily between days 13 and 21 of pregnancy, then assessed the female pups' spinal cord tissue and motor behavior. The rotarod test showed a significant increase in motor functions in the EMF group pups (p=0.037), while the open field test found no difference between groups. Pathological changes were observed in the spinal cords of the EMF group pups, and the researchers suggested these changes may have led to the increase in motor activity.
Haghani M, Shabani M, Moazzami K · 2013
Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.
Baş O et al. · 2013
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Poulletier de Gannes F et al. · 2012
Researchers exposed pregnant rats to a 2450 MHz Wi-Fi signal for 2 hours per day, 6 days per week, for 18 days at whole-body specific absorption rates of 0.08, 0.4, and 4 W/kg. The prenatal study examined fetuses delivered by caesarean section from five females per group, and dams with offspring were observed for 28 days after delivery with 15 females per group. No abnormalities were noted in pregnant rats and no significant signs of toxicity were observed in pre- and postnatal development of pups, even at the highest exposure level of 4 W/kg.
Mild KH, Andersen JB, Pedersen GF. · 2012
Several earlier studies used a GSM phone in stand-by mode as an exposure source and reported effects on sleep and testicular function. The authors explain that in stand-by mode the phone is only active during periodic location updates set by the network operator. Typical updates occur every 2 to 5 hours, and between updates the phone acts as a passive receiver with no microwave emission. They conclude that exposure in stand-by mode can be considered negligible.
Laudisi F et al. · 2012
Researchers exposed pregnant mice to WiFi signals at 2450 MHz with a specific absorption rate of 4 W/kg for two hours daily during gestation. Thymocyte count, phenotype, and proliferation were unchanged in exposed offspring. These null effects were consistent in both sexes at 5 and 26 weeks of age.
Kismali G, Ozgur E, Guler G, Akcay A, Sel T, Seyhan N. · 2012
Researchers exposed 13-month-old New Zealand White rabbits to whole-body 1800 MHz GSM-like radiofrequency radiation for 15 minutes per day for seven days. The study used four groups: non-pregnant controls, non-pregnant exposed, pregnant controls, and pregnant exposed. Lipid peroxidation measured as malondialdehyde levels did not change after exposure. Several blood chemistry parameters including cholesterol, total protein, albumin, uric acid, creatinine, creatine kinase, and CK-MB changed due to both pregnancy and RFR exposure. No indication of oxidative stress was detected in pregnant rabbits, though CK-MB and CK increases were described as remarkable.
Mouradi R, Desai N, Erdemir A, Agarwal A · 2012
The aim was to calculate the distance between a cell phone and a semen sample to set up an in vitro experiment that mimics real-life conditions with a phone in a trouser pocket separated by multiple tissue layers. The results indicated that the distance should be 0.8 cm to 1.8 cm greater than the anticipated distance between a cell phone and the testes. A computational model of scrotal tissues was designed considering the separating layers and used in simulations with the Finite Difference Time Domain method.
Ingole IV, Ghosh SK. · 2012
Researchers exposed chick embryos to radiofrequency radiation emitted by a cell phone by varying the duration of exposure to create different doses. Light microscopic examination revealed that developing dorsal root ganglion neurons suffered damage that was dose dependent. The damage persisted even when exposure-free periods were given between exposures.
Hässig M, Jud F, Spiess B. · 2012
Researchers examined a dairy farm where many calves were born with nuclear cataracts after a mobile phone base station was erected near the barn. Calves born there had a 3.5 times higher risk of heavy cataract compared to the Swiss average. The investigators excluded usual causes such as infection or poisoning, but the real cause of the increased incidence remains unknown.
Eskander EF, Estefan SF, Abd-Rabou AA. · 2012
Researchers assessed the role of exposure to radio frequency radiation from mobiles or base stations on human hormone profiles. The study showed significant decreases in volunteers' ACTH, cortisol, thyroid hormones, prolactin for young females, and testosterone levels.
Celik S, Aridogan IA, Izol V, Erdoğan S, Polat S, Doran S. · 2012
Researchers placed Wistar-Kyoto male rats into a control group with inactive cell phones and an experimental group with active cell phones for three months. No significant differences were found in testis weight, seminiferous tubule diameter, or histopathological evaluation between the groups. Electron microscopy showed increased membrana propria thickness, increased collagen fibers, extended capillary veins, vacuolization in Sertoli cells, electron-dense structures, and large lipid droplets in the exposed rats.
Baste V, Moen BE, Oftedal G, Strand LA, Bjørge L, Mild KH. · 2012
The study was a cohort study of Royal Norwegian Navy servicemen linked to the Medical Birth Registry of Norway, including singleton offspring born between 1967 and 2008 (n = 37,920). Exposure during the last 3 months before conception (acute) and exposure more than 3 months before conception (nonacute) were analyzed. Perinatal mortality and preeclampsia increased after service aboard fast patrol boats during an acute period and also after increased estimated radiofrequency exposure during an acute period, compared with service aboard other vessels. No associations were found between nonacute exposure and any of the reproductive outcomes.
Kesari KK, Behari J. · 2012
Seventy-day-old Wistar rats were exposed to mobile phone radiofrequency radiation for two hours per day for 45 days and compared with a sham-exposed group. RF-exposed animals had a significant decrease in testosterone and an increase in caspase-3 activity. Distortions in sperm head and mid piece of sperm mitochondrial sheath were observed via transmission electron microscopy. Progeny from RF-exposed rats showed significant decreases in number and weight compared to sham-exposed animals.
Jing J, Yuhua Z, Xiao-qian Y, Rongping J, Dong-mei G, Xi C. · 2012
Thirty-two pregnant rats were divided into four groups, with three groups receiving microwave radiation for 10, 30, or 60 minutes three times daily from the first day of pregnancy for 20 days. In the 30-minute and 60-minute exposure groups, superoxide dismutase and glutathione peroxidase decreased while malondialdehyde increased compared with controls. Noradrenaline and dopamine levels increased in the 10-minute exposure group but decreased in the 60-minute exposure group. The authors concluded that prenatal microwave radiation from cellular phones has certain harm on fetal rat brains.
Tsybulin O, Sidorik E, Kyrylenko S, Henshel D, Yakymenko I. · 2012
Researchers exposed fresh fertilized Japanese quail eggs to GSM 900 MHz cell phone radiation at 0.2 μW/cm² for either 38 hours or 14 days. The 38-hour exposure significantly increased the number of differentiated somites, and the 14-day exposure significantly increased total embryo survival. Hatchlings from exposed eggs showed significantly higher levels of thiobarbituric acid reactive substances in brain and liver tissue.
Aït-Aïssa S et al. · 2012
Pregnant rats were exposed to a 2.45 GHz Wi-Fi signal for 2 hours per day, 5 days per week, at whole-body SAR levels of 0, 0.08, 0.4, and 4 W/kg. Dams were exposed from days 6 to 21 of gestation, and then three newborns per litter were further exposed from birth to day 35 postnatal. Sera from pups were screened for antibodies against 15 different antigens using ELISA, and no change in humoral response was observed regardless of the types of biomarker and SAR levels. The researchers' observations suggested a lack of adverse effects of Wi-Fi exposure on delivery and general condition of the animals.
Aldad TS, Gan G, Gao XB, Taylor HS · 2012
Researchers used a mouse model to examine whether in-utero radiofrequency exposure from cellular telephones affects adult behavior. Mice exposed in the womb were hyperactive and had impaired memory, as measured using the object recognition, light/dark box, and step-down assays. The exposed mice also had dose-responsive impaired glutamatergic synaptic transmission onto layer V pyramidal neurons of the prefrontal cortex.
Redmayne M, Smith E, Abramson MJ. · 2011
Researchers explored school cellphone rules and adolescent exposure to cellphone microwave emissions during school using a census and survey. All schools banned private use of cellphones in class, but 43% of student participants admitted breaking this rule. A high-exposure group of risk-takers was identified for whom prohibited in-school use was positively associated with high texting rates, carrying the phone switched-on >10h/day, and in-pocket use. The authors reviewed reproductive bio-effect papers and concluded there is sufficient evidence and expert opinion to warrant an enforced school policy removing cellphones from students during the day.
Imai N, Kawabe M, Hikage T, Nojima T, Takahashi S, Shirai T. · 2011
Researchers exposed male Sprague-Dawley rats to a 1.95 GHz W-CDMA signal for 5 hours per day, 7 days a week for 5 weeks at whole-body SARs of 0.4 and 0.08 W/kg. There were no differences in body weight gain or weights of the testis, epididymis, seminal vesicles, and prostate among the groups. The number of sperm in the testis and epididymis were not decreased in the EMF exposed groups, and the testicular sperm count was significantly increased with the 0.4 SAR. Abnormalities of sperm motility or morphology and the histological appearance of seminiferous tubules, including the stage of the spermatogenic cycle, were not observed. Thus, under the present exposure conditions, no testicular toxicity was evident.
Divan HA, Kheifets L, Olsen J · 2011
Researchers used data from the Danish National Birth Cohort to examine prenatal cell phone use and developmental milestone delays in offspring up to 18 months of age. At 6 months the adjusted odds ratio for cognitive/language delay was 0.8 (95% CI 0.7-1.0) and for motor delay was 0.9 (95% CI 0.8-1.1). At 18 months the adjusted odds ratio for cognitive/language delay was 1.1 (95% CI 0.9-1.3) and for motor delay was 0.9 (95% CI 0.8-1.0). The researchers observed no evidence of an association and dose-response associations were also null.
Meo SA et al. · 2011
Forty male Wistar albino rats were divided into three groups: a control group of eight, a group exposed for 30 minutes/day, and a group exposed for 60 minutes/day for a total period of 3 months. Testicular morphological changes were examined under a light microscope. The 60-minute exposure group showed 18.75% hypospermatogenesis and 18.75% maturation arrest compared to controls, while the 30-minute group showed no abnormal findings.
Gutschi T et al. · 2011
Researchers examined 2110 men attending an infertility clinic from 1993 to October 2007 and divided them into cell phone users and non-users. Cell phone users had a significantly higher percentage of pathological sperm morphology (68.0%) compared to non-users (58.1%). Cell phone users also showed significantly higher testosterone and lower luteinizing hormone levels, while follicle stimulating hormone and prolactin levels did not differ significantly.
Falzone N, Huyser C, Becker P, Leszczynski D, Franken DR. · 2011
Highly motile human spermatozoa were exposed for 1 hour to 900-MHz mobile phone radiation at a specific absorption rate of 2.0 W/kg and examined at various times after exposure. The radiation did not affect the sperm acrosome reaction, but significant reductions were found in sperm head area and acrosome percentage of the head area among exposed sperm compared with unexposed controls. The mean number of zona-bound sperm was 22.8 in exposed samples versus 31.8 in controls, a statistically significant difference (p < 0.05). The researchers concluded that these results could indicate a significant effect of RF-EMF on sperm fertilization potential.
Kesari KK, Kumar S, Behari J. · 2011
The study investigated the effect of mobile phone exposure on fertility-related markers in 70-day-old male Wistar rats. Rats were exposed in Plexiglas cages for 2 hours a day for 35 days, with a specific absorption rate estimated at 0.9 W/kg. In exposed rats, antioxidant enzymes glutathione peroxidase and superoxide dismutase decreased, while malondialdehyde and free radical generation increased significantly. The researchers concluded that radiofrequency electromagnetic waves from commercially available cell phones might affect the fertilizing potential of spermatozoa.