Tkalec M, Malarić K, Pevalek-Kozlina B. · 2007
Researchers exposed duckweed (Lemna minor) to radiofrequency electromagnetic fields at 400 and 900 MHz, at field strengths of 10, 23, 41, and 120 V m−1, for 2 hours, and also tested a longer 4-hour exposure and modulated fields. After exposure, the researchers measured lipid peroxidation, H2O2 content, antioxidative enzyme activities and isoenzyme patterns, and HSP70 expression. At 900 MHz, almost all exposure treatments significantly increased lipid peroxidation and H2O2 content, mostly decreased PPX activity, and did not affect CAT activity. No differences in isoenzyme patterns of antioxidative enzymes or HSP70 level were found between control and exposed plants at either frequency.
Baohong W et al. · 2007
Researchers exposed human lymphocytes to 1.8 GHz microwaves at a SAR of 3 W/kg, ultraviolet ray C (UVC), or both, then measured DNA damage using the comet assay. Microwave exposure alone did not produce significantly more DNA damage than the control group. When combined with UVC, microwave exposure was associated with reduced DNA damage at 1.5-hour incubation but increased DNA damage at 4-hour incubation, compared with UVC alone.
Barcal J, Vozeh F · 2007
ECoG evaluation showed a distinct shift to lower frequency components in wild type mice but only gentle differences in Lurcher mutant mice. Hippocampal rhythmicity showed gentle changes with increase of higher frequencies and changes in theta oscillations in both healthy and mutant mice.
Zhao TY, Zou SP, Knapp PE. · 2007
Researchers exposed primary cultured neurons and astrocytes to GSM cell phone emissions at 1900 MHz for 2 hours. Neurons showed up-regulation of caspase-2, caspase-6, and Asc genes in both 'on' and 'stand-by' modes. Astrocytes showed up-regulation of the same genes only in 'on' mode and also up-regulated the Bax gene.
Barcal J, Vozeh F. · 2007
Researchers measured brain activity in mice while exposing them to 900 MHz radiofrequency radiation (the same frequency used by cell phones). They found that this exposure caused measurable changes in brain wave patterns in both the cortex and hippocampus - key brain regions involved in thinking and memory. The changes were most pronounced in healthy mice, suggesting that cell phone-frequency radiation can directly alter normal brain function.
Terao Y et al. · 2007
Researchers used a double-blind, counterbalanced crossover design with 10 normal subjects to test saccade performance before and after 30 minutes of mobile phone EMF exposure or sham exposure. They also measured hand reaction time to a visual signal. Saccade task parameters were unchanged after real or sham exposure, except for VGS and MGS latencies which also did not differ between exposure conditions. Hand reaction time shortened with repeated trials similarly for both exposures. The authors concluded that 30 minutes of mobile phone exposure has no significant short-term effect on saccade performance.
Speit G, Schütz P, Hoffmann H. · 2007
Researchers exposed ES1 cells to 1800 MHz RF-EMF at 2 W/kg SAR with intermittent exposure and tested for DNA damage using the alkaline comet assay and micronucleus test. They also tested V79 Chinese hamster cells and found no genotoxic effect in either assay. Quality control measures were used to rule out test performance issues, exposure failure, or evaluation bias.
Masuda H et al. · 2007
Researchers exposed the heads of rats for four weeks (60 min/day, 5 days/week) to RF-EMF at 2.4 W/kg of brain averaged specific absorption rate (BASAR). They measured blood-brain barrier permeability, leukocyte behavior, and plasma velocity using a closed cranial window method. No extravasation of dyes from pial venules was found, no significant changes in endothelial-adhering leukocytes occurred, and plasma velocity remained constant within the physiological range. These findings suggest that there were no effects on the cerebral microcirculation under the given RF-EMF exposure conditions.
Erogul O et al. · 2006
Researchers enrolled 27 men and divided each semen sample into two parts, exposing one to 900 MHz cellular phone radiation. Exposure caused a subtle decrease in rapid and slow progressive sperm movement and an increase in non-motile sperm. Sperm concentration did not differ significantly between exposed and unexposed samples.
Paulraj R, Behari J · 2006
Researchers exposed developing rat brains to microwave radiation at frequencies commonly used in WiFi and radar systems (2.45 and 16.5 GHz) for 35 days. They found statistically significant DNA damage in brain cells, specifically single-strand breaks that can interfere with normal cellular function. This suggests that chronic exposure to low-level microwave radiation during brain development may cause genetic damage.
Belyaev IY et al. · 2006
Researchers exposed rats to 915 MHz GSM microwaves for 2 hours at a SAR of 0.4 mW/g and then examined brain cells for DNA damage and gene expression changes. In the cerebellum, 11 genes were upregulated in a range of 1.34 to 2.74 fold and one gene was downregulated 0.48-fold (P < .0025). The exposure did not induce detectable DNA double strand breaks or changes in chromatin conformation.
Belyaev IY et al. · 2006
Scientists exposed rats to cell phone radiation at 915 MHz for 2 hours and found it changed gene activity in the brain without causing DNA breaks. The radiation altered the expression of 12 genes involved in brain functions like neurotransmitter regulation, the blood-brain barrier, and melatonin production. This suggests that even brief cell phone exposure can trigger biological changes in brain cells, even when DNA damage isn't detectable.
Ozguner F, Bardak Y, Comlekci S. · 2006
Researchers compared how well melatonin and caffeic acid phenethyl ester (CAPE) protected rat retinas from oxidative stress caused by exposure to 900 MHz mobile-phone radiation. Melatonin and CAPE were administered daily for 60 days to the rats prior to their EMR exposure. Retinal levels of the oxidative stress markers NO and MDA increased in EMR-exposed rats, while both melatonin and CAPE caused a significant reduction in those levels. Antioxidant enzyme activities (SOD, GSH-Px, and CAT) decreased in EMR-exposed animals, but both treatments significantly increased those activities.
Ozguner F, Bardak Y, Comlekci S · 2006
Researchers exposed rats to 900 MHz mobile phone radiation (the same frequency used by many cell phones) for 60 days and found it caused significant oxidative stress in eye tissue. The radiation increased harmful compounds and decreased protective antioxidant enzymes in the retina. However, rats given melatonin or caffeic acid supplements before exposure were largely protected from this damage, suggesting these antioxidants might help shield eye tissue from cell phone radiation effects.
Nylund R, Leszczynski D. · 2006
Researchers examined in vitro cell response to mobile phone radiation using two variants of a human endothelial cell line: EA.hy926 and EA.hy926v1. Gene expression changes were examined using cDNA Expression Arrays and protein expression changes were examined using 2-DE and PDQuest software. Gene and protein expression were altered in both examined cell lines after one hour of exposure at an average specific absorption rate of 2.8 W/kg, but the same genes and proteins were differently affected in each line.
Nylund R, Leszczynski D · 2006
Finnish researchers exposed human blood vessel cells to mobile phone radiation for one hour and found that genes and proteins changed differently in each cell type. This suggests that cellular response to phone radiation depends on the specific genetic makeup of cells, potentially explaining conflicting research results.
Oral B et al. · 2006
Researchers examined oxidative stress from a 900-MHz mobile phone and the possible protective effects of vitamins E and C on endometrial tissue in rats. Rats were divided into a sham control group, a 900-MHz EMF-exposed group (30 minutes daily for 30 days), and an EMF-exposed group treated with vitamins E and C before each exposure. Malondialdehyde, a marker of lipid peroxidation, and the proteins Bcl-2, Bax, caspase-3, and caspase-8 were measured in endometrial tissue. The EMF-exposed rats showed increased malondialdehyde levels and apoptosis, while vitamins E and C ameliorated oxidative tissue injury and apoptosis through free radical scavenging and antioxidant properties.
Oral B et al. · 2006
Turkish researchers exposed female rats to 900-MHz radiation (similar to older cell phones) for 30 minutes daily over 30 days and found it caused cell death and oxidative damage in the endometrium, the tissue lining the uterus. However, when rats were given vitamins E and C before exposure, these protective antioxidants significantly reduced the harmful effects. This suggests that cell phone radiation may damage reproductive tissues through oxidative stress, but antioxidants might offer some protection.
Christ A, Samaras T, Klingenböck A, Kuster N. · 2006
The study investigated electromagnetic near-field absorption in layered biological tissue from 30 MHz to 6000 MHz. Two effects can increase SAR in layered tissue versus homogeneous liquid: standing wave effects at larger distances depending on frequency and fat thickness, and high local skin absorption from reactive E-fields in the very close near-field. A conservative exposure estimate can be obtained by applying a multiplication factor of 1 to 3 to current dosimetric values.
Unknown authors · 2006
PMA treatment significantly increased ROS production in both cell types compared to sham or incubator controls. GSM-DTX exposure showed significantly different ROS production in monocytes compared to sham, but this was due to lowered ROS release during sham exposure. No ROS differences were detected in lymphocytes compared to sham or incubator control. Hsp70 expression in monocytes at 0, 1, and 2 hours post-exposure to GSM-DTX at 2 W/kg for 1 hour did not differ from incubator or sham controls.
Yurekli AI et al. · 2006
Researchers used a gigahertz transverse electromagnetic (GTEM) cell to expose rats to electromagnetic fields at the GSM base transceiver station frequency of 945 MHz. The power density applied was 3.67 W/m2 (specific absorption rate = 11.3 mW/kg), which the researchers described as well below current exposure limits. MDA levels increased and GSH concentrations decreased significantly (p < 0.0001) under this exposure. There was also a less significant (p = 0.0190) increase in SOD (superoxide dismutase) activity under EM exposure.
Forgacs Z et al. · 2006
Researchers studied the possible effects of whole-body 1800 MHz GSM-like microwave exposure on male reproduction in mice. After repeated exposure at 0.018-0.023 W/kg SAR, an elevated serum testosterone level was measured, but no histopathological alteration could be detected in the reproductive organs. Leydig cell cultures from exposed animals did not differ from controls in their steroidogenic response.
Xu S, Ning W, Xu Z, Zhou S, Chiang H, Luo J. · 2006
The study assessed the effects of microwave exposure on cultured rat hippocampal neurons using whole cell patch-clamp analysis combined with immunocytochemistry. Chronic exposure for 15 minutes per day over 8 days to GSM 1800-MHz microwaves at a SAR of 2.4 W/kg selectively reduced the amplitude of AMPA miniature excitatory postsynaptic currents, while the frequency of AMPA mEPSCs and the amplitude of NMDA mEPSCs did not change. The same exposure decreased the expression of postsynaptic density 95 (PSD95) in the cultured neurons.
Wilen J, Johansson A, Kalezic N, Lyskov E, Sandstrom M · 2006
Researchers investigated the effect of a mobile phone-like radiofrequency electromagnetic field on people who reported subjective symptoms when using mobile phones. Twenty subjects with mobile phone-related symptoms were matched with 20 controls without such symptoms, and each person took part in one true exposure session and one sham exposure session in random order. No significant differences related to radiofrequency exposure conditions were detected. The symptomatic group displayed a shift in low/high frequency ratio towards sympathetic dominance in the autonomous nervous system during tests, regardless of exposure condition.
Wilen J, Johansson A, Kalezic N, Lyskov E, Sandstrom M. · 2006
Swedish researchers exposed 20 people who experience symptoms from mobile phones and 20 people without symptoms to 900 MHz cell phone radiation for 30 minutes at levels typical of phone use. While the radiation didn't cause immediate measurable changes in either group, the symptomatic individuals showed different nervous system patterns during cognitive tests, suggesting their autonomic nervous systems may function differently regardless of radiation exposure.
