3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 293 studies in Cancer & Tumors

Effects of microwave exposure and Gemcitabine treatment on apoptotic activity in Burkitt's lymphoma (Raji) cells.

Canseven AG, Esmekaya MA, Kayhan H, Tuysuz MZ, Seyhan N. · 2014

Researchers exposed Burkitt's lymphoma cells (a type of cancer cell) to 1.8 GHz microwave radiation at levels similar to cell phones for 24 hours. The radiation significantly increased cell death and reduced cell survival, and when combined with a cancer drug called Gemcitabine, the effects were even stronger. This suggests that microwave radiation can affect cancer cells in ways that might interact with cancer treatments.

Extra-low-frequency magnetic fields alter cancer cells through metabolic restriction

Ying Li and Paul Heroux · 2014

Researchers exposed five different types of cancer cells to extremely low-frequency magnetic fields at levels commonly found in our environment (0.025-5 microTesla). After six days, all cancer cell types lost chromosomes, suggesting the magnetic fields disrupted cellular energy production in the mitochondria (the cell's power plants). The researchers found this effect was similar to what happens when cells are treated with drugs that block energy production.

Cancer & TumorsNo Effects Found

New Zealand adolescents' cellphone and cordless phone user-habits: are they at increased risk of brain tumours already? A cross-sectional study.

Redmayne M · 2013

Researchers surveyed 373 New Zealand adolescents (average age 12.3 years) about their cellphone and cordless phone use patterns. They found that 90% used both devices, with some already logging enough cordless phone hours to match the highest usage levels in major brain tumor studies. The study projected that if usage continued at current rates, many teens would reach exposure levels associated with increased brain tumor risk by their mid-teens.

Cancer & TumorsNo Effects Found

Mobile Phone Use and the Risk of Skin Cancer: A Nationwide Cohort Study in Denmark.

Poulsen AH et al. · 2013

Danish researchers followed 355,701 mobile phone subscribers for up to 20 years to see if cell phone use increased skin cancer rates. They found no evidence that mobile phone use raises the risk of melanoma, basal cell carcinoma, or squamous cell carcinoma on the head and neck (the areas most exposed to phone radiation). This large study suggests that the radiofrequency radiation from mobile phones does not significantly increase skin cancer risk.

Biophysical Evaluation of Radiofrequency Electromagnetic Field Effects on Male Reproductive Pattern.

Kesari KK, Kumar S, Nirala J, Siddiqui MH, Behari J. · 2013

This review examined how radiofrequency radiation from mobile phones affects male reproductive health, particularly when phones are carried in pockets near reproductive organs. The researchers found that mobile phone radiation increases harmful reactive oxygen species (molecules that damage cells) in testicular tissue, leading to decreased sperm count, DNA damage, and hormonal changes that can cause infertility. The study highlights the biological mechanisms by which everyday mobile phone use may be compromising men's fertility through oxidative stress and cellular damage.

Cancer & Tumors163 citations

Case-control study of the association between malignant brain tumours diagnosed between 2007 and 2009 and mobile and cordless phone use.

Hardell L, Carlberg M, Söderqvist F, Mild KH. · 2013

Swedish researchers studied 593 people with malignant brain tumors and compared their cell phone and cordless phone use to healthy controls. They found that long-term users (15+ years) had roughly double the risk of developing brain tumors, with the highest risk (3.3 times higher) seen in people who used older analog phones for over 25 years. The risk was particularly elevated when people held phones on the same side of the head where tumors developed.

Environmental risk factors for cancers of the brain and nervous system: the use of ecological data to generate hypotheses.

de Vocht F, Hannam K, Buchan I. · 2013

Researchers analyzed cancer data from 165 countries to explore potential environmental risk factors for brain and nervous system cancers. They found that countries with higher rates of mobile phone subscriptions consistently showed higher rates of brain cancer, with the data suggesting a latency period (time between exposure and disease) of at least 11-12 years, possibly over 20 years. While this type of population-level analysis cannot prove causation, it provides important signals that warrant further investigation into the relationship between wireless technology and brain cancer.

Meningioma patients diagnosed 2007--2009 and the association with use of mobile and cordless phones: a case--control study.

Carlberg M, Söderqvist F, Hansson Mild K, Hardell L. · 2013

Swedish researchers studied 709 people with meningiomas (brain tumors that grow on the protective membranes around the brain) to see if mobile and cordless phone use increased their risk. While overall phone use showed no clear link to these tumors, people with the highest usage (over 2,376 hours total) did show some increased risk. The authors concluded there wasn't enough evidence to prove phones cause meningiomas, but noted that longer-term studies are needed.

Cancer & Tumors184 citations

Mobile phone use and risk of brain neoplasms and other cancers: prospective study

Benson VS et al. · 2013

British researchers followed nearly 800,000 middle-aged women for 7 years to see if mobile phone use increased their risk of brain tumors and other cancers. They found no increased risk for most brain tumors, including the most common types (glioma and meningioma), but did find that women who used phones for 10+ years had more than double the risk of developing acoustic neuroma, a rare tumor of the hearing nerve. This large study provides mixed evidence about mobile phone safety, with reassurance for most brain cancers but concern for one specific type.

[Inhibitory effect of microwave radiation on proliferation of human pancreatic cancer JF305 cells and its mechanism].

Zhu W, Zhang W, Li Y, Xu J, Luo J, Jiang Y, Lu X, Lü S. · 2013

Researchers exposed human pancreatic cancer cells to microwave radiation at 2450 MHz (the same frequency used in WiFi and cell phones) for 20 minutes at various power levels. They found that the radiation inhibited cancer cell growth and triggered programmed cell death (apoptosis) through stress-related pathways. This suggests that microwave radiation can damage cellular functions even in cancer cells, which are typically more resilient than healthy cells.

Superposition of an incoherent magnetic field inhibited EGF receptor clustering and phosphorylation induced by a 1.8 GHz pulse-modulated radiofrequency radiation.

Sun W, Shen X, Lu D, Lu D, Chiang H · 2013

Researchers exposed human cells to 1.8 GHz radiofrequency radiation (similar to cell phone signals) and found it triggered abnormal clustering and activation of cellular receptors that control cell growth. Interestingly, when they added a weak 'noise' magnetic field alongside the RF exposure, it completely blocked these cellular changes at moderate power levels, suggesting the magnetic field provided some protection against RF-induced cellular disruption.

Exposure of tumor-bearing mice to extremely high-frequency electromagnetic radiation modifies the composition of fatty acids in thymocytes and tumor tissue.

Gapeyev AB, Kulagina TP, Aripovsky AV. · 2013

Researchers exposed mice with cancer to extremely high-frequency electromagnetic radiation (42.2 GHz) for 20 minutes daily and found it changed the fatty acid composition in their tissues. The radiation appeared to restore normal fatty acid levels in immune system cells (thymocytes) and altered the fatty acid makeup within tumor tissue itself. This suggests EMF exposure might influence cancer progression by changing how cells process fats.

Cancer & TumorsNo Effects Found

Mobile telecommunications and health: report of an investigation into an alleged cancer cluster in Sandwell, West Midlands.

Stewart A, Rao JN, Middleton JD, Pearmain P, Evans T · 2012

Researchers investigated whether a cell phone tower could be causing cancer cases on one street in England after residents expressed concern. They analyzed cancer data from 19 affected residents and compared it to regional averages over 12 years. While they found slightly higher cancer rates in the area during one time period, the cases didn't qualify as a true cancer cluster and couldn't be linked to the nearby cell tower.

Cancer & TumorsNo Effects Found

Use of wireless phones and the risk of salivary gland tumours: a case-control study.

Söderqvist F, Carlberg M, Hardell L · 2012

Swedish researchers studied 69 people with salivary gland tumors (mostly near the ear) and compared their phone use to 262 healthy controls. They found no increased risk of these tumors from wireless phone use, with an odds ratio of 0.8 (meaning slightly lower risk, though not statistically significant). The study provides reassurance for light-to-moderate phone users but acknowledges it cannot rule out risks from heavy, long-term use.

Cancer & TumorsNo Effects Found152 citations

Use of mobile phones and cordless phones is associated with increased risk for glioma and acoustic neuroma.

Hardell L, Carlberg M, Hansson Mild K. · 2012

Swedish researchers analyzed data from multiple studies on mobile and cordless phone use and brain tumor risk. They found that people who used mobile phones for 10+ years had a 71% increased risk of glioma (a type of brain tumor) in the temporal lobe, and those with the heaviest usage (1,640+ hours total) had more than double the risk. The study contributed to the World Health Organization's 2011 classification of mobile phone radiation as a 'possible carcinogen.'

Cancer & TumorsNo Effects Found115 citations

Mobile phone use and incidence of glioma in the Nordic countries 1979-2008: consistency check.

Deltour I et al. · 2012

Researchers analyzed brain tumor rates across Nordic countries from 1979-2008 to see if mobile phone use caused increases in glioma (a type of brain cancer). Despite widespread mobile phone adoption during this period, they found no significant increase in brain tumor rates that would match the elevated risks reported in some earlier studies. The findings suggest that either mobile phones pose lower cancer risks than some studies indicated, or that cancer development takes longer than the timeframes studied so far.

Cancer & TumorsNo Effects Found

Combined effects of 60 Hz electromagnetic field exposure with various stress factors on cellular transformation in NIH3T3 cells.

Lee HJ, Jin YB, Lee JS, Choi JI, Lee JW, Myung SH, Lee YS. · 2012

Researchers exposed mouse cells to 60 Hz magnetic fields (the type from power lines) to see if this could trigger cellular transformation into cancer-like cells. They tested the magnetic field alone and combined with known cancer-causing agents like radiation. The study found no evidence that the magnetic field exposure caused cell transformation or enhanced the cancer-causing effects of other agents.

DNA & Genetic DamageNo Effects Found

Effects on micronuclei formation of 60-Hz electromagnetic field exposure with ionizing radiation, hydrogen peroxide, or c-Myc overexpression.

Jin YB et al. · 2012

Korean researchers exposed mouse and human cells to 60 Hz magnetic fields (the same frequency used in electrical power systems) for 4 hours to see if this would cause DNA damage, either alone or when combined with known cancer-causing agents like radiation. They found no DNA damage from the magnetic field exposure, even when combined with other harmful substances that normally cause genetic damage.

Cancer cell proliferation is inhibited by specific modulation frequencies

Zimmerman JW et al. · 2012

Researchers exposed liver and breast cancer cells to radiofrequency electromagnetic fields at 27.12 MHz using specific modulation frequencies previously identified in cancer patients. They found that these cancer-specific frequencies significantly slowed the growth of cancer cells while leaving healthy cells completely unaffected. This suggests that precisely tuned electromagnetic frequencies might offer a targeted way to fight cancer without harming normal tissue.

Microwave electromagnetic field regulates gene expression in T-lymphoblastoid leukemia CCRF-CEM cell line exposed to 900 MHz.

Trivino Pardo JC, Grimaldi S, Taranta M, Naldi I, Cinti C. · 2012

Italian researchers exposed leukemia cells to 900 MHz microwave radiation (the same frequency used by many cell phones) and found that it altered gene expression patterns within the cells. The study identified specific biological pathways that were disrupted by the electromagnetic field exposure. This suggests that cell phone frequency radiation can trigger measurable changes at the genetic level in cancer cells.

2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca²⁺ influx in human leukemia cancer cells.

Nazıroğlu M, Ciğ B, Doğan S, Uğuz AC, Dilek S, Faouzi D. · 2012

Researchers exposed human leukemia cancer cells to 2.45 GHz radiation (the same frequency used by WiFi and microwaves) for periods ranging from 1 to 24 hours. They found that this radiation caused cancer cells to multiply more rapidly and triggered harmful oxidative stress by allowing excess calcium to flood into the cells. The longer the exposure, the more pronounced these effects became.

Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States.

Little MP et al. · 2012

Researchers compared cancer registry data from 1992-2008 with predictions based on two major studies that found increased brain cancer (glioma) risk from mobile phone use. They found that actual brain cancer rates remained steady during this period, even as mobile phone use increased from nearly 0% to almost 100% of the US population. This suggests the higher cancer risks reported in one Swedish study may not reflect real-world population-level impacts.

A population-based case-control study of radiofrequency exposure in relation to childhood neoplasm.

Li CY, Liu CC, Chang YH, Chou LP, Ko MC. · 2012

Taiwanese researchers analyzed cancer rates in over 2,600 children living near cell phone towers, comparing them to nearly 78,000 healthy children. They found that children living in areas with higher radiofrequency radiation from cell towers had a 13% increased risk of developing cancer overall. While the increased risk for specific cancers like leukemia and brain tumors wasn't statistically significant, the pattern suggests concern about long-term exposure to tower radiation.

Use of Mobile and Cordless Phones and Survival of Patients with Glioma.

Hardell L, Carlberg M. · 2012

Swedish researchers followed 1,251 brain tumor patients for over a decade to see if wireless phone use affected their survival after diagnosis. They found that patients with glioma (a type of brain tumor) who used mobile or cordless phones for more than 10 years had a 20% higher risk of dying compared to non-users. The effect was strongest for the most aggressive type of brain tumor (glioblastoma), where long-term phone users had a 30% higher death rate.

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