Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.
Showing 1,633 studies in Cellular Effects
Ross CL, Teli T, Harrison BS. · 2015
Researchers stimulated cAMP in CHO cells transfected with human mu-opioid receptors and exposed them to 5 Hz EMF. The 5 Hz EMF produced 23% greater inhibition of cAMP-treating cells than morphine treatment. When tested at 13 Hz, EMF produced results similar to controls.
Ulubay M et al. · 2015
Researchers studied the effects of prenatal 900 MHz EMF exposure on kidney histology in four-week-old male rats using seven groups including EMF-exposed and supplement-treated groups. EMF exposure significantly increased mean kidney and cortex volume compared to controls. EMF exposure decreased the total number of glomeruli compared to controls. Melatonin and omega-3 supplementation prevented the adverse effects of EMF on the kidneys.
Topal Z et al. · 2015
Adult pregnant rats were divided into control and experimental groups, and the experimental group was exposed to a 900-MHz EMF for 1 h daily during days 13-21 of pregnancy. Male pups from both groups were sacrificed on postnatal day 21. Biochemical analyses showed increased malondialdehyde and superoxide dismutase values and decreased glutathione levels in the exposed pups. Light microscopy revealed marked hydropic degeneration in the liver parenchyma, particularly in pericentral regions. Electron microscopy showed mitochondrial vacuolization, endoplasmic reticulum expansion, and necrotic hepatocytes.
Shivashankara AR et al. · 2015
The study assessed salivary enzymes, protein, and oxidant-antioxidant markers in young college students who used cell phones. Participants were divided into less mobile users and high mobile users based on duration and frequency of cell phone use. Unstimulated whole saliva samples were analyzed for amylase, lactate dehydrogenase (LDH), malondialdehyde (MDA), and glutathione (GSH). High mobile users showed significantly higher levels of amylase, LDH, and MDA than less mobile users. Decreases in total protein, GSH, and flow rate were not statistically significant.
Saygin M, Asci H, Ozmen O, Cankara FN, Dincoglu D, Ilhan I. · 2015
Six-week-old male Sprague Dawley rats were divided into four groups, including a sham group, an EMR-only group exposed to 2.45 GHz radiation for 3 hours per day for 30 days, an EMR plus gallic acid group, and a gallic acid-only group. EMR exposure increased malondialdehyde and total oxidant status levels, decreased total antioxidant status, and raised prostaglandin E2 and calcitonin gene-related peptide staining in testicular tubules. Gallic acid treatment lowered total oxidant status and oxidative stress index and raised total antioxidant status. It also reduced prostaglandin E2 and calcitonin gene-related peptide staining and increased testosterone and VEGF levels relative to the EMR-only group.
Olgar Y et al. · 2015
Researchers exposed rats to 2.1 GHz EMF for 2 hours per day over 10 weeks and compared them with sham-exposed rats. They measured sarcomere shortening, Ca2+ transients, and L-type Ca2+ currents in isolated ventricular myocytes. Exposure did not alter fractional shortening or Ca2+ transient amplitude, but reduced the isoproterenol-induced L-type Ca2+ current response while basal current density remained similar. Nitric oxide levels in heart tissue were significantly increased after EMF exposure.
Odacı E, Özyılmaz C. · 2015
Twenty-four adult male rats were divided into control, sham, and EMF groups. The EMF group was exposed to 900 MHz EMF for one hour per day over 30 days. Histopathologically, EMF-exposed rats showed vacuoles in seminiferous tubule basal membranes and edema in intertubular space. Seminiferous tubule diameters and germinal epithelium thickness were smaller, and apoptotic index was higher in the EMF group. Malondialdehyde, superoxide dismutase, catalase, and glutathione values decreased significantly in the EMF group compared to controls.
Marconi A et al. · 2015
The study used a randomized, double-blind, crossover design with 18 human volunteers exposed to GSM mobile phone radiation. Researchers measured two categories of oxidative stress biomarkers in blood and exhaled air, including markers of lipid oxidation and antioxidant defense. After 30 minutes of exposure, the overall entropy of the biomarker dataset decreased significantly, indicating a modulation of biomarker organization.
Ma HR, Ma ZH, Wang GY, Song CM, Ma XL, Cao XH, Zhang GH. · 2015
Twenty adult male Sprague-Dawley rats were randomly divided into a normal group and a radiated group exposed to 900 MHz mobile phone radiation 4 hours per day for 18 consecutive days. Serum levels of ALT and AST did not change significantly in the radiated group compared to the normal group. Liver malondialdehyde content increased and glutathione content decreased in the radiated group. Histopathology revealed diffuse hepatocyte swelling, vacuolation, and focal necrosis. Bax protein expression was higher, bcl-2 protein expression was lower, and hepatocyte apoptosis rates were higher in the radiated group.
Kazemi E et al. · 2015
The study investigated the effect of 900 MHz GSM on oxidative stress and intracellular ROS levels in human mononuclear cells, monocytes, and lymphocytes. Blood samples from 13 healthy volunteers were exposed to RF radiation from a mobile phone simulator for 2 hours, while control samples were not exposed. Mononuclear cells were isolated by density gradient centrifugation and ROS was measured using a CM-H2DCFDA fluorescence probe and flow cytometry. Results showed a significant increase in ROS production in monocyte-rich cell populations after exposure, but no significant change in lymphocyte-rich populations.
Hancı H et al. · 2015
Pregnant Sprague-Dawley rats were divided into control and EMF groups, and the EMF group received 900 MHz EMF for 1 hour per day. Male pups were examined on postnatal day 21 for effects on spleen and thymus. In the thymus, malondialdehyde levels were significantly higher and glutathione levels significantly decreased in exposed pups compared to controls. In the spleen, malondialdehyde and glutathione levels increased while superoxide dismutase values decreased significantly. Transmission electron microscopy revealed pathological changes in cell morphology in both thymus and spleen tissues.
Bin-Meferij MM, El-Kott AF · 2015
Barteri M et al. · 2015
The study examined the effects of 900 MHz electromagnetic field exposure on the catalytic activity of lactoperoxidase and horseradish peroxidase. Experimental evidence indicates that irradiation causes conformational changes of the active sites and influences the formation and stability of intermediate free radicals, as shown by enzyme kinetics, circular dichroism spectroscopy, and cyclic voltammetry.
Sun YL et al. · 2015
Researchers used a superconducting magnet that creates three apparent gravity levels to study RANKL-induced osteoclast differentiation from RAW264.7 cells. The magnetic field had no lethal effect on precursors but reduced nitric oxide release. Diamagnetic levitation increased osteoclast formation, bone resorption, and expression of RANK, Cathepsin K, MMP-9, and NFATc1 while decreasing RunX2, and caused morphological changes such as pseudopodial expansion, pedosome belt formation, and actin ring aggregation. The magnetic field component of the LGHMF attenuated osteoclast resorption activity. The authors conclude that diamagnetic levitation can serve as a ground-based microgravity simulator for bone cell research.
Osera C et al. · 2015
Researchers assessed whether short repeated pulsed EMF could trigger adaptive responses against oxidative insult in a neuronal cell model. A 40-minute overall pre-exposure, given as four 10-minute sessions per week, increased Mn-dependent superoxide dismutase activity in human neuroblastoma SH-SY5Y cells without affecting major physiological parameters. Pre-exposed cells showed decreased reactive oxygen species production after a 30-minute hydrogen peroxide challenge compared to non-pre-exposed cells. The authors suggest that specific PEMF treatments may have potential biological repercussions in diseases where oxidative stress is implicated.
Şahin A et al. · 2015
The study consisted of control, sham-exposed, and EMF-exposed groups with six rats in each. The EMF-exposed group received 900 MHz EMF for 1 hour per day for 30 days while the sham group was placed in the same jar without exposure. Stereological analysis revealed a significantly lower total number of pyramidal neurons in the cornu ammonis of EMF-exposed rats compared to both control and sham groups, and histopathology showed abnormal cells with dark cytoplasm and shrunken morphology.
Özgür A et al. · 2015
Twelve adult Wistar albino rats were divided into two groups of six, with one group exposed to electromagnetic waves for 30 days and the other serving as unexposed controls. Histological analysis revealed neuronal degeneration signs such as increased vacuolization, pyknotic cells, and edema in the cochlear nucleus of exposed rats. Auditory brainstem response wave latencies did not differ between the exposed and control groups. The authors concluded that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system.
Wang C et al. · 2015
Wang D et al. · 2015
Exposure significantly reduced progressive sperm motility and viability and increased sperm head defects. Early apoptosis was higher after exposure, while DNA methylation of the H19 ICR and KvDMR1 imprinting genes did not change significantly.
Malka N. Halgamuge, See Kye Yak and Jacob L. Eberhardt · 2015
Soybean seedlings pre-grown for 4 days were exposed for 2 h to GSM 900 MHz pulsed radiation or continuous wave radiation at amplitudes of 5.7 and 41 V m(-1) in a gigahertz transverse electromagnetic cell. Exposure to higher amplitude (41 V m(-1)) GSM radiation resulted in diminished outgrowth of the epicotyl. Exposure to lower amplitude (5.7 V m(-1)) GSM radiation did not influence outgrowth of epicotyl, hypocotyls, or roots. Higher amplitude CW radiation reduced root outgrowth while lower CW exposure reduced hypocotyl outgrowth. A separate 5-day exposure to 0.56 V m(-1) GSM radiation reduced epicotyl and hypocotyl growth but stimulated root outgrowth.
Liu YQ, Gao YB, Dong J, Yao BW, Zhao L, Peng RY. · 2015
Researchers exposed Wistar rats to 0, 5, 10, and 50 mW/cm² microwave to observe dynamic pathological changes in the sinus nodes. At 10 and 50 mW/cm², acute changes from 1 to 28 days included disorganized sinoatrial node cells, cell swelling, cytoplasmic condensation, nuclear pyknosis, anachromasis, swollen and empty mitochondria, and blurred and focally dissolved myofibrils. Chronic changes from 6 to 12 months at the same intensities included reduced parenchymal cells, increased collagen fibers, and extracellular matrix remodeling of interstitial cells. The researchers concluded that 10 and 50 mW/cm² microwave could cause structural damages in the sinoatrial node and extracellular matrix remodeling in rats.
Kumar A, Singh HP, Batish DR, Kaur S, Kohli RK. · 2015
After 7 days, exposure for 4 h caused significant growth and biochemical alterations. Root and coleoptile length were reduced, with coleoptile length showing a 23 % reduction after 4 h exposure. Photosynthetic pigments and total carbohydrates declined by 13 and 18 %, while α- and β-amylase activities increased by ∼92 and 94 % after 4 h exposure. Acid invertase and alkaline invertase activities increased by 88 and 266 %, whereas phosphatase activities rose up to 2 h then declined after longer exposure.
Holovská K et al. · 2015
Researchers exposed mature Wistar rats to an electromagnetic field of frequency 2.45 GHz and mean power density of 2.8 mW/cm2 for 3 h/d for 3 wk. Liver samples were obtained 3 h after the last irradiation and processed histologically for light and transmission electron microscopy. The researchers concluded that EMR exposure produced adverse effects on rat liver.
Grémiaux A et al. · 2015
Researchers exposed small rose bush plants to high-frequency electromagnetic fields and followed shoot growth for over a one-month period after exposure. Shoots that arose from post-formed secondary buds showed delayed and significantly reduced growth of 45%, while shoots from pre-formed buds and plants exposed at the 5-leaf stage showed no growth modification. The measured plant energy uptake suggested this biological response was likely not due to a thermal effect.
Furtado-Filho OV et al. · 2015
Researchers exposed young rats to 950 MHz ultra-high-frequency electromagnetic radiation to measure oxidative damage to DNA, proteins, and lipids in the left and right cerebral cortex. Radiation exposure lasted 30 minutes per day for up to 27 days, with a specific absorption rate ranging from 1.32 to 1.14 W/kg. In neonates, no modification of the biomarkers tested was detected, while 6-day-old exposed rats showed increased carbonylated proteins in the right cerebral cortex and decreased blood glucose. The researchers concluded that the elevated carbonylated proteins in the right cerebral cortex did not appear to be a consequence of oxidative stress.