3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 481 studies in DNA & Genetic Damage

DNA & Genetic DamageNo Effects Found

Effect of high-frequency electromagnetic fields with a wide range of SARs on chromosomal aberrations in murine m5S cells.

Komatsubara Y et al. · 2005

Japanese researchers exposed mouse cells to 2.45 GHz microwave radiation (the same frequency used in microwave ovens and WiFi) for 2 hours at extremely high power levels up to 100 watts per kilogram. They found no chromosomal damage or genetic changes in the cells, even at these intense exposure levels that far exceed what humans typically experience from wireless devices.

DNA & Genetic DamageNo Effects Found

Effects of 1-week and 6-week exposure to GSM/DCS radiofrequency radiation on micronucleus formation in B6C3F1 Mice.

Gorlitz BD et al. · 2005

Researchers exposed mice to cell phone radiation (GSM and DCS frequencies) for 2 hours daily over 1 and 6 weeks to test whether it causes DNA damage in blood cells and other tissues. They found no increase in micronuclei (tiny fragments that indicate genetic damage) in any of the cell types examined, even at radiation levels up to 33.2 mW/g. This suggests that cell phone-type radiation at these exposure levels does not cause detectable genetic damage in mice.

DNA & Genetic DamageNo Effects Found

Genotoxicity evaluation of electromagnetic fields generated by 835-MHz mobile phone frequency band.

Chang SK et al. · 2005

Researchers exposed bacterial cells to 835-MHz mobile phone radiation at high intensity (4 W/kg SAR) for 48 hours to test whether it causes DNA damage or genetic mutations. The study found no evidence that this radiofrequency radiation caused DNA breakdown or increased mutation rates in the bacterial test systems. This suggests that mobile phone frequencies may not directly damage genetic material under these laboratory conditions.

DNA & Genetic DamageNo Effects Found

Evaluation of genotoxic effects in human peripheral blood leukocytes following an acute in vitro exposure to 900 MHz radiofrequency fields.

Zeni O et al. · 2005

Italian researchers exposed human white blood cells to 900 MHz cell phone radiation for 2 hours at levels similar to what phones emit during calls. They tested multiple ways to detect DNA damage but found no statistically significant genetic harm at either exposure level tested. The study suggests that short-term exposure to cell phone radiation at typical use levels may not cause immediate DNA damage in blood cells.

Microwaves from GSM Mobile Telephones Affect 53BP1 and gamma-H2AX Foci in Human Lymphocytes from Hypersensitive and Healthy Persons.

Markova E, Hillert L, Malmgren L, Persson BR, Belyaev IY · 2005

Researchers exposed human immune cells (lymphocytes) to microwave radiation from GSM mobile phones and found that the radiation caused DNA damage markers similar to heat shock stress. The study compared cells from both healthy people and those who report electromagnetic sensitivity, finding similar responses in both groups. This suggests that mobile phone radiation can trigger cellular stress responses that indicate potential DNA damage, regardless of whether someone feels sensitive to electromagnetic fields.

2.45GHz radiofrequency fields alter gene expression in cultured human cells.

Lee S et al. · 2005

Researchers exposed human immune cells to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwave ovens) for 2-6 hours and found it altered the activity of hundreds of genes. After just 2 hours, 221 genes changed their expression patterns, increasing to 759 genes after 6 hours. Importantly, genes related to cell death increased their activity while genes controlling normal cell division decreased, and this happened without any heating effects.

Cytogenetic damage in mobile phone users: preliminary data.

Gandhi G, Singh P. · 2005

Researchers examined cellular damage in mobile phone users by analyzing two types of cells: lymphocytes (white blood cells) from blood samples and cells from inside the cheek. They found increased genetic damage in both cell types among mobile phone users, including more cells with damaged DNA structures (micronuclei) and abnormal chromosome changes that indicate the body's genetic material is being harmed.

Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neural progenitor cells.

Nikolova T et al. · 2005

German researchers exposed developing brain cells to both power line frequencies (50 Hz) and cell phone frequencies (1.71 GHz) for 6 hours to study genetic effects. They found that both types of electromagnetic fields triggered changes in genes that control cell death and DNA damage responses, though the cells themselves appeared to function normally afterward. This suggests that EMF exposure can activate cellular stress responses even when no obvious harm is visible.

Genetic damage in mobile phone users: some preliminary findings.

Gandhi G, Anita · 2005

Researchers tested 24 mobile phone users' blood cells for genetic damage and found significantly more DNA breaks and chromosomal abnormalities compared to non-users. The study used two different laboratory tests to measure cellular damage in white blood cells from people exposed to mobile phone radiation between 800-2000 MHz. These findings suggest that everyday mobile phone use may cause measurable genetic damage at the cellular level.

Low-intensity electromagnetic fields induce human cryptochrome to modulate intracellular reactive oxygen species

Regoli F et al. · 2005

Researchers exposed land snails to 50-Hz magnetic fields (the same frequency used in power lines) for up to two months and measured cellular damage. The magnetic field exposure triggered oxidative stress, causing the snails' cells to produce harmful molecules that damaged DNA and cellular membranes. This study demonstrates that power-line frequency electromagnetic fields can disrupt cellular defenses and cause biological damage in living organisms.

Microwaves from GSM mobile telephones affect 53BP1 and gamma-H2AX foci in human lymphocytes from hypersensitive and healthy persons.

Markovà E, Hillert L, Malmgren L, Persson BR, Belyaev IY. · 2005

Researchers exposed human immune cells (lymphocytes) to microwave radiation from GSM mobile phones for one hour and found it caused DNA damage markers similar to heat shock. The study examined cells from both healthy people and those who report electromagnetic hypersensitivity, finding similar responses in both groups. This demonstrates that cell phone radiation can trigger cellular stress responses and DNA damage at exposure levels well below current safety standards.

Studying the synergistic damage effects induced by 1.8GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro.

Baohong Wang et al. · 2005

Researchers exposed human immune cells to 1.8 GHz cell phone radiation (the same frequency used by many mobile phones) for 2-3 hours to see if it damages DNA. While the radiation alone didn't harm DNA, it significantly amplified the damage when cells were also exposed to certain toxic chemicals. This suggests cell phone radiation may make our cells more vulnerable to other environmental toxins.

Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline.

Aitken RJ, Bennetts LE, Sawyer D, Wiklendt AM, King BV. · 2005

Researchers exposed mice to cell phone-level radiation (900 MHz) for 12 hours daily over a week and examined sperm DNA for damage. While the mice appeared healthy and sperm counts looked normal, detailed genetic analysis revealed significant DNA damage in both the mitochondria (cellular powerhouses) and nuclear DNA of sperm cells. This suggests that radiofrequency radiation can harm genetic material in reproductive cells even when other measures appear normal.

Interaction of Microwaves and a Temporally Incoherent Magnetic Field on Single and Double DNA Strand Breaks in Rat Brain Cells.

Lai H, Singh NP · 2005

Researchers exposed rats to cell phone-frequency microwaves (2450 MHz) for 2 hours and found significant DNA damage in brain cells. However, when they simultaneously exposed the rats to a weak magnetic field with random fluctuations, it completely blocked the DNA damage from occurring. This suggests that certain types of magnetic field exposure might actually protect against some forms of EMF damage.

Oxidative DNA damage in rats exposed to extremely low frequency electromagnetic fields.

Yokus B, Cakir DU, Akdag MZ, Sert C, Mete N · 2005

Turkish researchers exposed laboratory rats to 50 Hz magnetic fields (the same frequency as power lines) for 50 and 100 days to measure DNA damage. They found that exposed rats had significantly more oxidative DNA damage and cellular damage markers compared to unexposed rats, with the damage increasing over time. This suggests that long-term exposure to power-frequency magnetic fields may cause cumulative genetic damage at the cellular level.

Cellular Effects103 citations

915 MHz microwaves and 50 Hz magnetic field affect chromatin conformation and 53BP1 foci in human lymphocytes from hypersensitive and healthy persons.

Belyaev IY et al. · 2005

Researchers exposed white blood cells from healthy people and those with electromagnetic sensitivity to cell phone radiation (915 MHz). Both groups showed identical DNA structural changes similar to heat stress, confirming that electromagnetic fields cause measurable biological effects in human cells.

Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro.

Baohong Wang et al. · 2005

Scientists tested whether cell phone radiation (1.8 GHz) makes DNA more vulnerable to damage from toxic chemicals. While radiation alone caused no harm, it significantly increased genetic damage when combined with two specific chemicals, suggesting phone exposure may amplify other environmental toxins' effects.

Individual responsiveness to induction of micronuclei in human lymphocytes after exposure in vitro to 1800-MHz microwave radiation.

Zotti-Martelli L et al. · 2005

Italian researchers exposed blood cells to cell phone radiation (1800 MHz) for three hours. The radiation caused genetic damage that increased with longer exposure and higher power levels. Crucially, people showed dramatically different sensitivity levels, suggesting some individuals may be more vulnerable to EMF effects.

Interaction of microwaves and a temporally incoherent magnetic field on single and double DNA strand breaks in rat brain cells

Lai H, Singh NP · 2005

Researchers exposed rats to microwave radiation at cell phone frequencies (2450 MHz) for 2 hours and found significant DNA damage in brain cells. However, when they simultaneously exposed the rats to a weak magnetic field with random fluctuations, it completely blocked the DNA damage from occurring. This suggests that certain types of magnetic field exposure might actually protect against microwave-induced genetic damage.

Non-thermal DNA breakage by mobile-phone radiation (1800MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro.

Diem E, Schwarz C, Adlkofer F, Jahn O, Rudiger H. · 2005

Researchers exposed human cells and rat cells to 1800 MHz mobile phone radiation at levels similar to what phones emit during calls. After 16 hours of exposure, both cell types showed DNA strand breaks (damage to genetic material). The damage occurred at non-thermal levels, meaning it wasn't caused by heating effects, and intermittent exposure patterns caused more damage than continuous exposure.

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