6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Whole Body / GeneralNo Effects Found

Extremely low- frequency electromagnetic field induces acetylation of heat shock proteins and enhances protein folding

Huang Z, Ito M, Zhang S, Toda T, Takeda J-I, Ogi T, Ohno K · 2023

Researchers examined the effect of extremely low-frequency electromagnetic fields on AML12 and HEK293 cells. After 3 h of exposure, protein expression of HSP70 and HSP90 decreased while their acetylation increased, enhancing binding to HOP. Mitochondrial amount decreased but ATP levels and maximal oxygen consumption increased, leading to fewer protein aggregates and higher cell viability. The acetylation of HSPs returned to baseline by 12 h.

Shortwave radiation-induced reproductive organ damage in male rats by enhanced expression of molecules associated with the calpain/Cdk5 pathway and oxidative stress

Yao B et al. · 2023

Researchers exposed male Wistar rats to 27 MHz continuous shortwaves at power densities of 0, 5, 10, or 30 mW/cm2 for 6 min. They analyzed serum INSL3 and anti-sperm antibody levels, sperm motility and malformation, testicular structure, and oxidative stress markers including SOD, CAT, MDA, calpain, and Cdk5 expression at multiple time points after exposure. Exposure decreased serum INSL3 levels, increased anti-sperm antibodies, decreased percentage of class A+B sperm, increased sperm malformation, injured testicular tissue, decreased SOD and CAT activities, increased MDA content, and increased calpain1, calpain2, and Cdk5 expression in testicular tissue.

Combined effects of EMP and RF field on emotional behavior in mice

Qin T et al. · 2023

Researchers exposed male mice for one week to electromagnetic pulse at 650 kV/m for 1,000 pulses and 4.9 GHz radiofrequency at 50 W/m 2 for one hour per day. They used open field test, tail suspension test, and Y-maze to assess anxiety, depression-like behavior, and spatial memory. Proteomic analysis showed hippocampal proteins enriched in glutamatergic and GABAergic synapses, and histological examination revealed autophagy-associated cell death in the amygdala.

High Frequency Electromagnetic Radiation Stimulates Neuronal Growth and Hippocampal Synaptic Transmission

Ma S, Li Z, Gong S, Lu C, Li X, Li Y · 2023

Researchers investigated the effect of 0.138 THz radiation on dynamic neuronal growth and synaptic transmission efficiency. Cumulative 0.138 THz radiation did not cause neuronal death and promoted the dynamic growth of neuronal cytosol and protrusions. There was a cumulative effect of terahertz radiation on the promotion of neuronal growth. 0.138 THz waves improved synaptic transmission efficiency in the hippocampal CA1 region in a slow and continuous process. The improved synaptic transmission can continue for more than 10 min after terahertz radiation ends and is associated with an increase in dendritic spine density.

Effects of Nonthermal Radiofrequency Stimulation on Neuronal Activity and Neural Circuit in Mice

Hao Y et al. · 2023

Researchers established a spatial memory impairment model by exposing mice to 2856-MHz RFR at thermal noise levels (≤1 °C). Glutamate release in the dorsal hippocampus CA1 region did not change significantly, while dopamine release was reduced. RFR enhanced calcium activity in glutamatergic CA1 pyramidal neurons through nonthermal mechanisms, and this activity returned to baseline after exposure ended. The dopamine reduction was linked to decreased density of dopaminergic projections from the locus coeruleus to the dorsal hippocampus. Artificially activating dopamine axon terminals or D1 receptors in the dorsal hippocampus CA1 improved memory damage in exposed mice.

Electronic device and social network use and sleep outcomes among adolescents: the EHDLA study

Gaya AR et al. · 2023

The research was a cross-sectional study of 1101 Spanish adolescents aged 12 to 17. Participants' age, sex, sleep, psychosocial health, Mediterranean diet adherence, sport practice, and screen time were measured with a questionnaire. Linear and Poisson regression models were used with a significance threshold of p < 0.05. In girls, cell phone and WhatsApp use were linked to sleep-related problems, with Mediterranean diet adherence and psychosocial health also important.

Effect of Terahertz Waves on the Structure of the Aβ42 Monomer, Dimer, and Protofibril: Insights from Molecular Dynamics Simulations

Chen C, Yan Z-S Ma Y-Q, Ding H-M · 2023

Researchers used all-atom molecular dynamics simulations to investigate how terahertz waves affect the structure of Aβ42 monomer, dimer, and tetramer. Terahertz waves at 42.55 THz enhanced intramolecular interactions in the monomer and intermolecular interactions in the dimer by resonating with specific molecular vibrations. This increased β-structure content in the monomer and significantly enhanced binding energy in the dimer. Terahertz waves also mildly stabilized tetrameric protofibrils by enhancing interactions among peripheral peptides.

Terahertz waves regulate the mechanical unfolding of tau pre-mRNA hairpins

Zhang Q, Yang L, Wang K, Guo L, Ning H, Wang S, Gong Y · 2023

Researchers used steered molecular dynamics simulations to study how THz electromagnetic waves affect the mechanical unfolding of RNA hairpins. The results show that THz waves can promote unfolding during the initial phase at 4-21.8 THz, enhance structural stability at 23.8 and 25.5 THz, or weaken structural stability at 37.4 and 41.2 THz.

Impacts of Radio-Frequency Electromagnetic Field (RF-EMF) on Lettuce (Lactuca sativa)—Evidence for RF-EMF Interference with Plant Stress Responses

Unknown authors · 2023

The study examined RF-EMF effects on lettuce (Lactuca sativa) in indoor and outdoor settings using DECT (1890–1900 MHz) and Wi-Fi (2.4 GHz and 5 GHz) frequencies. Under greenhouse conditions, RF-EMF had only a minor impact on fast chlorophyll fluorescence kinetics and did not affect flowering time. In field conditions, RF-EMF exposure significantly reduced photosynthetic efficiency, accelerated flowering, down-regulated VDE and ZEP genes, and lowered FV/FM and NPQ under light stress.

Exposure to Electromagnetic Fields from Mobile Phones and Fructose consumption Coalesce to Perturb Metabolic Regulators AMPK/SIRT1-UCP2/FOXO1 in Growing Rats

Unknown authors · 2023

Weaned Wistar rats were divided into four groups and exposed to EMF (1,760 MHz, 2 h/day) and/or 15% fructose solution for 8 weeks. In the hypothalamic tissue of the combined exposure group, expressions of SIRT1, FOXO1, p-PI3K, p-AKT, Complex III, UCP2, MnSOD, and catalase and activities of OXPHOS and GSH were significantly decreased compared to the normal, EMF-only, and fructose-only groups. In hepatic tissue of the combined exposure group, expressions of p-AMPKα, SIRT1, FOXO1, IRS1, p-PI3K, Complex I, II, III, IV, V, UCP2, and MnSOD and activities of OXPHOS, SOD, catalase, and GSH were significantly reduced compared to the normal group.

Sirtuin 3 controls cardiac energetics and protects against oxidative stress in electromagnetic radiation-induced cardiomyopathy

Niu T et al. · 2023

Researchers found that Sirt3 protein expression was down-regulated in a mouse model of electromagnetic radiation-induced cardiomyopathy. Sirt3 knockout markedly exaggerated decreases in cardiac energetics and increases in oxidative stress in microwave-irradiated mice. Cardiac-specific SIRT3 overexpression protected the hearts from these effects and rescued cardiac malfunction. Sirt3 maintained the AMPK signaling pathway in microwave-irradiated hearts in vivo.

Adverse effects of 900, 1800 and 2100 MHz radiofrequency radiation emitted from mobile phones on bone and skeletal muscle

Unknown authors · 2023

Fifty-six rats weighing 200–250 g were divided into healthy and diabetic groups, each with sham and radiofrequency radiation exposure at 900, 1800, and 2100 MHz. Over a month, each group spent two hours per day in a Plexiglas carousel, with experimental groups exposed to radiofrequency radiation and sham groups not exposed. Researchers performed three-point bending tests and radiological evaluations on the right tibia bones and measured CAT, GSH, MDA, and IMA in skeletal muscle tissue. Significant differences were found in biomechanical properties, radiological evaluations, and muscle tissue measurements between groups (p < .05). Average whole-body SAR values were 0.026 W/kg for GSM 900 MHz, 0.164 W/kg for 1800 MHz, and 0.173 W/kg for 2100 MHz.

(2022) Estimation of RF and ELF dose by anatomical location in the brain from wireless phones in the MOBI-Kids study

Calderón et al · 2022

Researchers created an algorithm for the MOBI-Kids study to estimate cumulative specific energy from RF fields and cumulative induced current density from ELF fields in the brain of subjects aged 10 to 24 years. The algorithm considered age, tumour location, phone models, usage patterns, and communication system prevalence over time. Median RF and ELF doses were substantially higher for GSM than 3G systems and varied considerably by brain location. Agreement between RF dose estimates and phone use variables was moderate to null depending on communication system, while agreement for ELF dose was higher but also system-dependent. Duration and number of calls may not be adequate proxies for dose as communication systems become more complex over time.

Assessment of cortisol secretory pattern in workers chronically exposed to ELF-EMF generated by high voltage transmission lines and substations

Touitou Y, Selmaoui B, Lambrozo J · 2022

Researchers investigated the effects of ELF-EMFs on cortisol secretion in 14 men working in extra-high voltage substations. Magnetic field exposure was measured over seven days with geometric means ranging from 0.1 to 2.6 μT. Blood samples were taken hourly from 20:00 to 08:00 the next morning. Compared to unexposed controls, higher field intensity had a significant effect on cortisol secretory pattern. This study strongly suggests that chronic exposure to ELF-EMFs alters peak-time serum cortisol levels.

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