3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Effects of 3 Hz and 60 Hz Extremely Low Frequency Electromagnetic Fields on Anxiety-Like Behaviors, Memory Retention of Passive Avoidance and Electrophysiological Properties of Male Rats.

Rostami A et al. · 2016

Researchers exposed male rats to extremely low frequency electromagnetic fields (ELF-EMF) at 3 Hz and 60 Hz for several days and measured effects on brain activity and behavior. They found that both frequencies significantly reduced the rats' movement and decreased the firing rate of neurons in the locus coeruleus, a brain region important for arousal and attention. The study also detected widespread changes in brain proteins, suggesting that ELF-EMF exposure can alter brain function at multiple biological levels.

Abnormal feeding behaviour in spinalised rats is mediated by hypothalamus: Restorative effect of exposure to extremely low frequency magnetic field.

Ambalayam S, Jain S, Mathur R. · 2016

Researchers studied how spinal cord injuries affect eating behavior in rats and whether extremely low frequency magnetic fields could help. They found that spinal cord injury disrupts normal feeding patterns by affecting a brain region called the hypothalamus, but exposure to magnetic fields restored normal eating behavior and promoted nerve healing. This suggests magnetic field therapy might help address neurological complications from spinal injuries.

Pernicious effects of long-term, continuous 900-MHz electromagnetic field throughout adolescence on hippocampus morphology, biochemistry and pyramidal neuron numbers in 60-day-old Sprague Dawley male rats.

Kerimoğlu G et al. · 2016

Researchers exposed young rats to 900 MHz radiation (cell phone frequencies) daily during adolescence. Brain examination revealed significant hippocampus damage including dead neurons, fewer healthy brain cells, and oxidative stress markers. This suggests cell phone radiation during development may cause lasting memory and learning problems.

Adverse effects in lumbar spinal cord morphology and tissue biochemistry in Sprague Dawley male rats following exposure to a continuous 1-h a day 900-MHz electromagnetic field throughout adolescence.

Kerimoğlu G, Aslan A, Baş O, Çolakoğlu S, Odacı E. · 2016

Researchers exposed young rats to cell phone frequency radiation (900 MHz) for just one hour daily throughout their adolescent development and found significant damage to their spinal cords. The exposed rats showed structural abnormalities, increased cell death, and biochemical markers of oxidative stress in spinal cord tissue. This suggests that even limited daily exposure to radiofrequency radiation during critical developmental periods can harm nervous system tissue.

Exposure to mobile phone electromagnetic field radiation, ringtone and vibration affects anxiety-like behaviour and oxidative stress biomarkers in albino wistar rats

Shehu A, Mohammed A, Magaji RA, Muhammad MS · 2016

Researchers exposed rats to mobile phone radiation for 4 weeks using different phone modes (silent, vibration, ringtone, or both) and measured anxiety-like behavior and cellular damage markers. All exposed groups showed increased anxiety compared to controls, and rats exposed to ringtone modes also showed decreased antioxidant enzyme activity. This suggests that mobile phone radiation may affect both brain function and cellular health, even from relatively short daily exposures.

Maternal exposure to a continuous 900-MHz electromagnetic field provokes neuronal loss and pathological changes in cerebellum of 32-day-old female rat offspring.

Odacı E et al. · 2016

Pregnant rats exposed to cell phone-frequency radiation (900-MHz) for one hour daily produced offspring with significantly fewer brain cells in the cerebellum, the region controlling movement and coordination. The brain damage persisted into young adulthood, suggesting prenatal EMF exposure may harm developing brains.

Effects of Long Term Exposure of 900-1800 MHz Radiation Emitted from 2G Mobile Phone on Mice Hippocampus- A Histomorphometric Study.

Mugunthan N et al. · 2016

Researchers exposed mice to radiation from 2G mobile phones (900-1800 MHz) for 48 minutes daily over 1-6 months and examined brain tissue under microscopes. They found significant damage to the hippocampus, the brain region crucial for memory and learning, including reduced numbers of neurons and smaller cell nuclei. This suggests that prolonged mobile phone radiation exposure may harm brain cells in ways that could affect cognitive function.

Effects of radiofrequency field exposure on glutamate-induced oxidative stress in mouse hippocampal HT22 cells

Kim JY, Kim HJ, Kim N, Kwon JH, Park MJ · 2016

Scientists exposed mouse brain cells to radiofrequency radiation and glutamate, a brain chemical that becomes toxic during diseases like Alzheimer's. RF exposure alone caused minimal harm, but when combined with glutamate, it dramatically increased cell death, suggesting RF radiation may worsen brain damage in diseased conditions.

Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900 MHz electromagnetic field during early and mid-adolescence

İkinci A et al. · 2016

Researchers exposed young male rats to 900 MHz electromagnetic fields (similar to cell phone radiation) for one hour daily during adolescence and examined their spinal cords. They found significant damage including deterioration of the protective myelin sheaths around nerve fibers, tissue atrophy, and increased oxidative stress markers. This suggests that RF radiation exposure during critical developmental periods may harm the nervous system's structure and function.

Effects of Electromagnetic Radiation from Smartphones on Learning Ability and Hippocampal Progenitor Cell Proliferation in Mice

Choi Y-J, Choi Y-S · 2016

Researchers exposed mice to smartphone electromagnetic radiation for 9-11 weeks to study effects on brain function and memory. While the radiation didn't impair spatial memory or damage brain cell growth, it did activate astrocytes (brain support cells that respond to injury) and caused hyperactivity-like behavior weeks after exposure ended. This suggests smartphone radiation may trigger subtle brain changes that aren't immediately obvious but could have delayed effects.

Activity and expression of acetylcholinesterase in PC12 cells exposed to intermittent 1.8 GHz 217-GSM mobile phone signal.

Valbonesi P, Franzellitti S, Bersani F, Contin A, Fabbri E. · 2016

Italian researchers exposed rat brain cells to cell phone radiation at the legal safety limit for 24 hours and found that a key brain enzyme called acetylcholinesterase increased by 40%. This enzyme is crucial for memory, learning, and proper brain function, and disruptions to it are linked to neurodegenerative diseases like Alzheimer's.

Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts.

Sun C, Wei X, Fei Y, Su L, Zhao X, Chen G, Xu Z · 2016

Researchers exposed mouse embryonic cells to 1,800 MHz radiofrequency radiation (similar to cell phone signals) at high power levels for 1-12 hours and found it initially caused DNA breaks. However, after prolonged exposure, the cells' DNA repair systems became so active that DNA damage dropped below normal background levels - a phenomenon called hormesis where low doses of a harmful substance trigger beneficial protective responses.

Effects of pre- and postnatal exposure to 1880-1900MHz DECT base radiation on development in the rat.

Stasinopoulou M et al. · 2016

Researchers exposed pregnant rats to DECT phone base station radiation (the same frequency as cordless phones) for 12 hours daily during pregnancy and early life. They found increased heart rates in developing embryos, altered birth measurements in newborns, and significant brain cell loss in the hippocampus region of 22-day-old pups. These brain changes occurred whether the animals were exposed only before birth or both before and after birth.

GSM 900 MHz Microwave Radiation-Induced Alterations of Insulin Level and Histopathological Changes of Liver and Pancreas in Rat.

Mortazavi SM et al. · 2016

Researchers exposed rats to cell phone radiation (GSM 900 MHz) for either 3 or 6 hours daily over 7 days to study effects on insulin production and organ health. While insulin levels remained unchanged, the radiation caused inflammatory damage in the liver and harmed insulin-producing cells in the pancreas, with longer exposure times producing more severe damage.

Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.

He Q, Sun Y, Zong L, Tong J, Cao Y. · 2016

Researchers exposed mouse bone marrow cells to cell phone-level radiation for three hours daily over five days. The cells showed significant increases in PARP-1, a protein that repairs DNA damage, suggesting the radiation triggered cellular stress requiring DNA repair mechanisms.

Glial markers and emotional memory in rats following acute cerebral radiofrequency exposures.

Barthélémy A et al. · 2016

Researchers exposed rats to radiofrequency radiation for 15 minutes at different intensities and measured brain inflammation and memory function. They found that even low-level exposure (1.5 W/kg) caused significant brain inflammation, while higher exposure (6 W/kg) impaired long-term memory and increased inflammation in multiple brain regions. This study provides direct evidence that brief RF exposure can trigger brain inflammation and memory problems in living animals.

Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts.

Sun C, Wei X, Fei Y, Su L, Zhao X, Chen G, Xu Z. · 2016

Scientists exposed mouse cells to cell phone radiation and discovered it initially damaged DNA but then activated repair systems that left cells healthier than unexposed ones. This "hormesis" effect had never been seen with phone radiation before, suggesting potential protective cellular responses.

Adaptive response in mouse bone-marrow stromal cells exposed to 900-MHz radiofrequency fields: Gamma-radiation-induced DNA strand breaks and repair.

Ji Y, He Q, Sun Y, Tong J, Cao Y. · 2016

Chinese researchers exposed mouse bone marrow cells to cell phone-level radiofrequency radiation (900 MHz) for 4 hours daily over 5 days, then hit them with gamma radiation to damage their DNA. Surprisingly, the cells that received RF preconditioning showed less DNA damage and repaired themselves faster than cells exposed to gamma radiation alone, suggesting RF exposure may trigger protective cellular responses.

Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice.

Salunke BP, Umathe SN, Chavan JG. · 2016

Researchers exposed mice to 50 Hz magnetic fields (the same frequency as power lines) for up to 120 days and found it caused significant anxiety-like behavior. The study identified that these fields disrupt brain chemistry by affecting NMDA receptors and increasing glutamate levels in key brain regions. This suggests that long-term exposure to power-frequency magnetic fields can alter brain function and behavior.

Effects of short term and long term Extremely Low Frequency Magnetic Field on depressive disorder in mice: Involvement of nitric oxide pathway.

Madjid Ansari A et al. · 2016

Researchers exposed mice to extremely low frequency magnetic fields (the type generated by power lines and electrical appliances) to study effects on depression-like behavior. They found that short-term exposure (2 hours) had no effect, but long-term exposure (2 hours daily for 2 weeks) actually reduced depressive symptoms in the mice. The study suggests this effect may work through changes in nitric oxide levels in the brain.

Long-term exposure to ELF-MF ameliorates cognitive deficits and attenuates tau hyperphosphorylation in 3xTg AD mice.

Hu Y et al. · 2016

Researchers exposed genetically modified mice with Alzheimer's disease to extremely low frequency magnetic fields (50Hz, 500μT) for three months daily. The magnetic field exposure improved cognitive function, reduced brain cell death, and decreased tau protein abnormalities that are hallmarks of Alzheimer's disease. This suggests that controlled magnetic field exposure might have therapeutic potential for neurodegenerative conditions.

Effects of short term and long term extremely low frequency magnetic field on depressive disorder in mice: Involvement of nitric oxide pathway.

Ansari AM et al. · 2016

Researchers exposed mice to extremely low frequency magnetic fields (the type emitted by power lines and electrical devices) for either 2 hours once or 2 hours daily for 2 weeks. They found that long-term exposure reduced depression-like behavior in the mice, while short-term exposure interfered with antidepressant medications. This suggests that chronic EMF exposure may alter brain chemistry and affect how psychiatric medications work.

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