3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Cause-specific mortality in cellular telephone users.

Dreyer NA, Loughlin JE, Rothman KJ · 1999

Researchers attempted to track cause-specific mortality (death rates from specific diseases) among cellular phone users in 1994, focusing on brain-related deaths. However, the study was cut short when a class-action lawsuit blocked access to the mortality data after just one year of surveillance. This prevented the researchers from completing their investigation into whether cell phone use was associated with increased death rates from brain tumors or other causes.

Evaluation in humans of the effects of radiocellular telephones on the circadian patterns of melatonin secretion, a chronobiological rhythm marker.

de Seze R, Ayoub J, Peray P, Miro L, Touitou Y · 1999

French researchers exposed 38 young men to cell phone radiation (GSM 900 MHz and DCS 1800 MHz) for 2 hours daily over 4 weeks to test whether it would disrupt melatonin, the hormone that regulates sleep cycles. They found no changes in melatonin patterns during or after exposure. This suggests that typical cell phone use may not directly interfere with the body's natural sleep hormone production.

Adrenergic nerve plexuses of heart and adrenal and myocardial catecholamines of spontaneously hypertensive rats under the influence of electromagnetic irradiation in the millimeter range].

Belousova TE, Kargina-Terent'eva RA · 1999

Russian researchers exposed hypertensive rats to millimeter wave radiation at frequencies used in medical therapy devices (42,194 MHz and 53,534 MHz). They found the radiation reduced nerve density in heart tissue and decreased stress hormone production in both the heart and adrenal glands. This suggests millimeter wave exposure can suppress the sympathetic nervous system that controls heart rate and blood pressure responses.

Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves.

Adey WR et al. · 1999

Researchers exposed pregnant rats and their offspring to cell phone radiation (836 MHz) for 24 months to study brain tumor development. Surprisingly, the radiation-exposed animals showed fewer brain tumors than unexposed controls, both naturally occurring tumors and those induced by a cancer-causing chemical. This unexpected protective effect was most pronounced in rats that died early in the study, where radiation exposure reduced chemically-induced brain tumors by a statistically significant amount.

Hyperactivity caused by a nitric oxide synthase inhibitor is countered by ultra-wideband pulses.

Seaman RL, Belt ML, Doyle JM, Mathur SP · 1999

Researchers exposed mice to ultra-wideband electromagnetic pulses at extremely high field strength (102,000 volts per meter) to see if it could counteract the hyperactive behavior caused by blocking nitric oxide production in the brain. The electromagnetic exposure successfully eliminated the drug-induced hyperactivity, suggesting the pulses somehow restored normal nitric oxide function. This demonstrates that pulsed electromagnetic fields can directly influence brain chemistry and behavior in laboratory animals.

Effect of amplitude modulated RF radiation on calcium ion efflux and ODC activity in chronically exposed rat brain.

Paul Raj R, Behari J, Rao AR · 1999

Researchers exposed young rats to radiofrequency radiation at cell phone-like levels for 35 days and found significant changes in brain chemistry, including increased calcium movement and enzyme activity. These cellular changes in developing brains suggest RF exposure during growth may disrupt normal brain function.

Sleep & Circadian RhythmNo Effects Found163 citations

Human sleep under the influence of pulsed radiofrequency electromagnetic fields: a polysomnographic study using standardized conditions.

Wagner, P, Roschke, J, Mann, K, Hiller, W, Frank, C · 1998

German researchers monitored the sleep patterns of 24 healthy men using brain wave measurements while exposing them to cell phone-like radiofrequency signals (900 MHz GSM signals). The study found no statistically significant changes in sleep quality, REM sleep duration, or brain wave patterns during EMF exposure. The researchers noted their failure to replicate previous findings might indicate that EMF effects on sleep depend on the specific exposure dose.

Brain & Nervous SystemNo Effects Found

Does acute exposure to the electromagnetic field emitted by a mobile phone influence visual evoked potentials?

Urban, P, Lukas, E, Roth, Z · 1998

Researchers exposed 20 healthy volunteers to electromagnetic fields from a Motorola mobile phone for 5 minutes and measured visual evoked potentials (electrical brain responses to visual stimuli) to see if phone radiation affected brain function. They found no changes in brain activity after the exposure. This small pilot study suggests short-term mobile phone use may not immediately disrupt this particular aspect of brain function.

Brain & Nervous SystemNo Effects Found

Ultra-wideband electromagnetic pulses and morphine-induced changes in nociception and activity in mice.

Seaman RL, Belt ML, Doyle JM, Mathur SP · 1998

Researchers exposed mice to extremely high-intensity ultra-wideband electromagnetic pulses (99-105 kV/m) for up to 45 minutes and tested whether this affected their pain sensitivity and movement, including when combined with morphine. The study found no changes in pain response or activity levels in either normal mice or those given morphine. This suggests these particular electromagnetic pulses did not interfere with the nervous system pathways that control pain and movement.

SAR / Device AbsorptionNo Effects Found193 citations

Differences in energy absorption between heads of adults and children in the near field of sources.

Schonborn F, Burkhardt M, Kuster N · 1998

Researchers used computer simulations to compare how much cell phone radiation is absorbed by children's heads versus adults' heads at 900 MHz and 1,800 MHz frequencies. They found no significant differences in radiation absorption between children and adults, contradicting earlier studies that suggested children absorb more radiation. This finding has important implications for safety standards, which are currently based only on adult head models.

Brain & Nervous SystemNo Effects Found

Car phones and car crashes: an ecologic analysis.

Min ST, Redelmeier DA · 1998

Researchers analyzed car accident data from Toronto between 1984-1993 to see if cellular phone use correlated with increased crashes. They found that areas with the biggest increases in collision rates actually had the smallest increases in phone usage. The study concluded that cellular phones' effects on driving safety are too small to detect using this type of population-level analysis.

Brain & Nervous SystemNo Effects Found

Effects of pulsed high-frequency electromagnetic fields on the neuroendocrine system

Mann et al. · 1998

Researchers exposed healthy volunteers to 900 MHz electromagnetic fields (similar to older cell phones) while they slept and measured hormone levels throughout the night. They found a small, temporary increase in cortisol (stress hormone) right after exposure began, but no effects on growth hormone, reproductive hormones, or melatonin. The study suggests our bodies may quickly adapt to this type of EMF exposure.

CardiovascularNo Effects Found

No effects of pulsed high-frequency electromagnetic fields on heart rate variability during human sleep

Mann, K, Roschke, J, Connemann, B, Beta, H · 1998

Researchers monitored heart rate patterns during sleep in healthy adults exposed to radiofrequency fields from digital mobile phones. They found no changes in heart rate variability or the balance between the sympathetic and parasympathetic nervous systems (the body's automatic stress and rest responses) during EMF exposure compared to placebo conditions. The study suggests that weak pulsed RF fields from mobile phones don't disrupt the heart's natural rhythm control during sleep.

DNA & Genetic DamageNo Effects Found141 citations

DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia.

Malyapa RS et al. · 1998

Researchers exposed rats to 2450 MHz microwave radiation (the same frequency used in microwave ovens and some WiFi devices) for 2 hours to see if it would damage DNA in brain cells, as a previous study had suggested. They found no DNA damage in either the brain's cortex or hippocampus regions, contradicting the earlier research. This study suggests that short-term exposure to this type of radiation at moderate levels may not cause immediate genetic damage to brain cells.

DNA & Genetic DamageNo Effects Found

DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia.

Malyapa RS et al. · 1998

Researchers exposed rats to microwave radiation at 2450 MHz (the same frequency used in microwave ovens) for 2 hours to test whether it causes DNA breaks in brain cells. They found no DNA damage in either the brain's cortex or hippocampus regions, contradicting an earlier study that reported such damage. This suggests that short-term exposure to this type of microwave radiation at moderate levels may not harm brain cell DNA.

Alteration of diurnal rhythms of blood pressure and heart rate to workers exposed to radiofrequency electromagnetic fields.

Szmigielski et al. · 1998

Polish researchers studied 61 workers exposed to radiofrequency EMF at radio stations and compared their daily blood pressure and heart rate patterns to 42 unexposed workers. They found that EMF exposure disrupted the natural daily rhythms of both blood pressure and heart rate, with higher exposure levels causing more pronounced effects. This suggests that radiofrequency radiation may interfere with the body's autonomic nervous system, which controls these vital functions.

Preliminary report: symptoms associated with mobile phone use.

Hocking, B · 1998

Researchers surveyed 40 mobile phone users who experienced unusual symptoms like burning sensations and dull aches in their head and ears during or after phone calls. These symptoms typically started within minutes of use and lasted up to an hour afterward, with 75% of cases linked to digital phones. The study found that most people got relief by changing how they used their phones or switching to different devices.

Comparison of symptoms experienced by users of analogue and digital mobile phones: a Swedish-Norwegian epidemiological study.

Hanson Mild et al. · 1998

Swedish and Norwegian researchers compared symptoms between users of older analog mobile phones (NMT) and newer digital phones (GSM) in a large study of over 17,000 people. Surprisingly, they found that digital phone users actually reported fewer symptoms like warmth sensations around the ear compared to analog users, contradicting their initial hypothesis. However, both phone types showed a clear pattern: the more people talked on their phones, the more they experienced symptoms like headaches, fatigue, and ear warmth.

Cellular phone effects on otoacoustic emissions.

Grisanti G et al. · 1998

Italian researchers studied how cellular phone radiation affects the inner ear by measuring otoacoustic emissions (tiny sounds the ear produces naturally). They found that the electromagnetic fields from phones altered these natural ear responses in nearly all test subjects. This suggests that phone radiation can interfere with normal inner ear function, potentially affecting hearing.

Effects of microwaves emitted by cellular phones on human slow brain potentials.

Freude, G, Ullsperger, P, Eggert ,S, Ruppe, I · 1998

German researchers studied how cell phone radiation affects brain wave patterns by having men perform simple finger movements and complex visual tasks while exposed to phone emissions. They found that radiation significantly altered slow brain potentials (electrical patterns that prepare the brain for action) during the demanding cognitive task, but not during simple movements. This suggests cell phone radiation can interfere with brain electrical activity during mentally challenging activities, even when performance appears normal.

Mobile phones modulate response patterns of human brain activity.

Eulitz, C, Ullsperger, P, Freude, G, Elbert ,T · 1998

German researchers examined how mobile phone radiation affects brain activity by measuring electrical responses while people listened to sounds. They found that phone radiation altered specific patterns of brain activity, particularly in higher frequency brain waves when people were actively processing important sounds. This suggests mobile phones can directly change how our brains process information.

[Observations of changes in neurobehavioral functions in workers exposed to high-frequency radiation].

Duan L, Shan Y, Yu X · 1998

Chinese researchers tested brain function in workers exposed to high-frequency electromagnetic radiation using standardized tests recommended by the World Health Organization. They found that exposed workers scored significantly lower on multiple brain performance measures compared to unexposed controls, and these changes correlated with symptoms of neurasthenia (a condition involving mental fatigue and cognitive difficulties). This suggests that occupational exposure to high-frequency EMF can measurably impair cognitive function.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.