3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
Research Guide

5G vs 4G Radiation: What's Different?

Based on 653 peer-reviewed studies

Share:

People often ask whether 5G is more dangerous than 4G. This question requires understanding how 5G technology differs from previous generations and what research exists on each.

5G networks operate across multiple frequency bands. Low-band 5G (600-900 MHz) is actually similar to 4G frequencies. Mid-band 5G (2.5-4 GHz) overlaps with existing WiFi. High-band 5G (24-40+ GHz, "millimeter wave") represents the newest frequencies for consumer wireless exposure.

This page compares what research shows about radiation exposure from 5G versus 4G technologies.

Key Research Findings

  • 5G uses multiple frequency bands with different characteristics
  • Millimeter waves (high-band 5G) penetrate less deeply into tissue
  • More cell towers can actually reduce individual exposure levels

Related Studies (653)

DNA & Genetic DamageNo Effects Found

Cytogenetic effects of 18.0 and 16.5 GHz microwave radiation on human lymphocytes in vitro.

Hansteen IL et al. · 2009

Norwegian researchers exposed human immune cells (lymphocytes) to high-frequency microwave radiation at levels similar to industrial applications for 53 hours to test for DNA damage. They found no statistically significant genetic damage from either continuous 18.0 GHz or pulsed 16.5 GHz radiation, though the pulsed exposure showed a non-significant trend toward increased genetic abnormalities that the researchers said needs further study.

Cellular EffectsNo Effects Found

Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts.

Billaudel B, Taxile M, Ruffie G, Veyret B, Lagroye I. · 2009

Researchers exposed mouse cells to cell phone signals (DAMPS and GSM) for one hour to see if it would increase activity of ornithine decarboxylase (ODC), an enzyme linked to cell growth and potentially cancer development. They found no significant changes in ODC activity at exposure levels of 2.5 and 6 W/kg, contradicting some earlier studies that reported increased enzyme activity. This suggests that under controlled temperature conditions, these specific cell phone signals may not trigger this particular cellular response.

Cellular EffectsNo Effects Found

Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells.

Billaudel B et al. · 2009

Researchers exposed human brain tumor cells to cell phone radiation similar to DAMPS and GSM signals for up to 24 hours, then measured changes in an enzyme called ornithine decarboxylase (ODC) that's involved in cell growth. They found no changes in ODC activity regardless of the type of signal, exposure duration, or radiation intensity. This suggests that typical cell phone radiation levels don't affect this particular cellular process in brain cells.

DNA & Genetic DamageNo Effects Found

Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-Chloro-4-(dichloromethyl)-5-Hydroxy-2(5h)-furanone (MX).

Sannino A et al. · 2009

Researchers exposed human skin cells to 900 MHz radiofrequency radiation (similar to cell phone signals) for 24 hours at 1 W/kg to test for DNA damage. They found no genetic damage from the RF exposure alone, even when testing cells from people with Turner's syndrome who may be more sensitive. The radiation also didn't make cells more vulnerable to damage from a known water contaminant.

Oxidative StressNo Effects Found

Reactive oxygen species formation is not enhanced by exposure to UMTS 1950 MHz radiation and co-exposure to ferrous ions in Jurkat cells

Brescia F et al. · 2009

Researchers exposed human immune cells to 1950 MHz cell phone radiation (the frequency used by 3G networks) to see if it would trigger oxidative stress, a cellular damage process linked to aging and disease. They tested various exposure durations and power levels, both alone and combined with iron compounds known to cause oxidative stress. The study found no increase in harmful reactive oxygen species or cell death from the radiation exposure under any conditions tested.

Brain & Nervous SystemNo Effects Found

Expression of the water channel protein, aquaporin-4, in mouse brains exposed to mobile telephone radiofrequency fields

Finnie JW, Blumbergs PC, Cai Z, Manavis J · 2009

Researchers exposed mice to cell phone radiation at 900 MHz for either one hour or two years to see if it would increase a brain protein called aquaporin-4, which rises when the blood-brain barrier becomes leaky. They found no increase in this protein after either short or long-term exposure, suggesting that cell phone radiation at this level doesn't make the blood-brain barrier more permeable.

Derangement of chick embryo retinal differentiation caused by radiofrequency electromagnetic fields.

Zareen N, Khan MY, Minhas LA. · 2009

Researchers exposed developing chicken embryos to mobile phone radiation during critical stages of eye development and found significant disruptions in retinal growth and pigmentation. Embryos exposed for 10 days showed stunted retinal growth, while those exposed for 15 days showed excessive growth with intense pigmentation changes. This suggests that radiofrequency radiation from mobile phones can interfere with normal eye development in developing embryos.

Mobile and cordless telephones, serum transthyretin and the blood-cerebrospinal fluid barrier: a cross-sectional study

Soderqvist F, Carlberg M, Hardell L · 2009

Swedish researchers examined whether long-term mobile and cordless phone use affects the blood-cerebrospinal fluid barrier by measuring transthyretin, a protein that helps protect the brain. They found that men who used phones longer had higher transthyretin levels, while women showed elevated levels when blood was drawn soon after phone calls. These changes suggest that radiofrequency radiation may alter the brain's protective barriers.

Effects of mobile phone radiofrequency on the structure and function of the normal human hemoglobin.

Mousavy SJ et al. · 2009

Researchers exposed human hemoglobin (the protein in red blood cells that carries oxygen) to cell phone radiofrequency radiation at 910MHz and 940MHz frequencies. They found that the radiation altered hemoglobin's ability to carry oxygen and changed its molecular structure, with greater effects at higher radiation intensities and longer exposure times. This suggests that cell phone radiation could potentially interfere with your blood's fundamental ability to transport oxygen throughout your body.

Immune System128 citations

Disturbance of the immune system by electromagnetic fields-A potentially underlying cause for cellular damage and tissue repair reduction which could lead to disease and impairment.

Johansson O. · 2009

This comprehensive review by Swedish researcher Olle Johansson examined dozens of studies on how electromagnetic fields affect the immune system. The research shows that EMF exposure disrupts immune function by triggering allergic and inflammatory responses while impairing the body's ability to repair tissue damage. These immune disruptions occur at EMF levels well below current safety limits and may increase disease risk, including cancer.

The effects of microwave emitted by cellular phones on ovarian follicles in rats.

Gul A, Celebi H, Uğraş S. · 2009

Researchers exposed pregnant rats to cell phone radiation throughout pregnancy and found their female offspring had significantly fewer ovarian follicles (egg-containing structures) compared to unexposed controls. The study suggests that prenatal exposure to cell phone microwaves may harm developing reproductive organs. This raises important questions about potential fertility impacts from wireless device exposure during pregnancy.

Effect of electromagnetic field induced by radio frequency waves at 900 to 1800 MHz on bone mineral density of iliac bone wings.

Atay T et al. · 2009

Turkish researchers measured bone density in the hip area of 150 men who regularly carried cell phones for an average of 6.2 years and 14.7 hours daily. They found slightly lower bone density on the side where phones were carried compared to the unexposed side, though the difference wasn't statistically significant. The findings suggest that long-term phone carrying might affect bone health in ways that could matter for medical procedures requiring bone grafts.

Aluminum, calcium ion and radiofrequency synergism in acceleration of lymphomagenesis.

Anghileri LJ, Mayayo E, Domingo JL. · 2009

Researchers studied how aluminum combined with radiofrequency radiation affects cancer development in mice with lymphoma. They found that this combination accelerated cancer progression and death, causing rapid growth of lymphoid tissue in the spleen and liver. The effect was strongest when aluminum could easily release ions in the body, suggesting that aluminum and RF radiation work together to disrupt normal cellular processes.

Derangement of chick embryo retinal differentiation caused by radiofrequency electromagnetic fields.

Zareen N, Khan MY, Ali Minhas L · 2009

Researchers exposed developing chicken embryos to 1800 MHz radiofrequency radiation from a mobile phone during critical stages of eye development. They found that the radiation disrupted normal retinal development, causing both growth abnormalities and changes in pigmentation patterns depending on when during development the exposure occurred. This suggests that EMF radiation can interfere with the precise developmental processes needed for proper eye formation.

Radio frequency magnetic fields disrupt magnetoreception in American cockroach.

Vácha M, Puzová T, Kvícalová M · 2009

Researchers studied how radio frequency magnetic fields affect the ability of American cockroaches to sense Earth's magnetic field for navigation. They found that weak RF fields at specific frequencies disrupted the insects' magnetic navigation system, with the strongest disruption occurring at 1.2 MHz at levels as low as 12-18 nanotesla. This suggests that common electromagnetic pollution could interfere with the natural navigation abilities of insects and other animals.

Effects of radiofrequency electromagnetic fields on seed germination and root meristematic cells of Allium cepa L.

Tkalec M et al. · 2009

Scientists exposed onion seeds to cell phone-level radiation (400 and 900 MHz) for two hours. While seeds germinated normally, their dividing cells showed significant chromosome damage and abnormalities. This suggests radiofrequency radiation can disrupt cellular processes even when overall growth appears unaffected.

900 MHz modulated electromagnetic fields accelerate the clathrin-mediated endocytosis pathway.

Moisescu MG, Leveque P, Verjus MA, Kovacs E, Mir LM. · 2009

French researchers exposed mouse cells to 900 MHz cell phone radiation and found it accelerated endocytosis, the process cells use to absorb nutrients and other substances. This suggests cell phone signals can alter fundamental cellular functions at the molecular level, potentially affecting how cells process essential materials.

Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells.

Del Vecchio G et al. · 2009

Researchers exposed developing brain cells to cell phone radiation (900 MHz GSM at 1 W/kg) for up to 6 days and found that the radiation significantly reduced the growth of neurites - the branch-like extensions that neurons use to connect with each other. This disruption occurred in both mouse and rat brain cells, suggesting that cell phone radiation may interfere with normal brain development at the cellular level.

Reactive oxygen species formation is not enhanced by exposure to UMTS 1950 MHz radiation and co-exposure to ferrous ions in Jurkat cells.

Brescia F et al. · 2009

Researchers exposed human immune cells to 3G cell phone radiation at levels similar to what phones emit, testing whether this radiation creates harmful reactive oxygen species (unstable molecules that can damage cells). Even after 24 hours of exposure, the radiation produced no increase in these damaging molecules and didn't harm cell survival. The study also tested whether radiation might amplify damage from iron compounds, but found no such interaction.

Extremely low frequency electromagnetic fields activate the ERK cascade, increase hsp70 protein levels and promote regeneration in Planaria

Reba Goodman et al. · 2009

Researchers exposed flatworms (planaria) to 60 Hz magnetic fields at 80 milliGauss for one hour twice daily during regeneration after being cut in half. The EMF-exposed worms regenerated faster than unexposed controls, with tail portions growing eyes 48 hours earlier and showing increased levels of stress proteins typically associated with healing and repair processes.

Further Reading

For a comprehensive exploration of EMF health effects and practical protection strategies, explore these books by R Blank and Dr. Martin Blank.