Mokarram P, Sheikhi M, Mortazavi SMJ, Saeb S, Shokrpour N · 2017
Researchers exposed male rats to 900 MHz GSM cell phone radiation for 4 hours and found it altered DNA methylation patterns in colon cells, specifically affecting the estrogen receptor gene. DNA methylation is a process that controls gene activity and plays a role in cancer development. This suggests that cell phone radiation may cause epigenetic changes that could potentially increase colorectal cancer risk.
Kim JH, Kim HJ, Yu DH, Kweon HS, Huh YH, Kim HR. · 2017
Researchers studied the effects of RF-EMF exposure on synaptic vesicles in the cortical neurons of mice. C57 BL/6 mice were exposed to 835 MHz RF-EMF at 4.0 W/kg SAR for 5 hours daily. The density of synaptic vesicles was significantly decreased in the presynaptic boutons of cortical neurons after exposure. The expression of synapsins I/II genes and proteins was also significantly decreased in exposed mice.
Marjanovic Cermak AM, Pavicic I, Trosic I · 2017
Human neuroblastoma SH-SY5Y cells were exposed to 1800 MHz radiofrequency radiation for 10, 30, and 60 minutes at an electric field strength of 30 V m-1 and a specific absorption rate of 1.6 W kg-1. Cell viability remained within normal physiological values after radiation exposure. Significantly higher ROS levels were observed at every radiation exposure time tested. After 60 minutes of exposure, the radiation caused significant lipid and protein damage. The highest glutathione concentration was detected after 10 minutes of exposure.
Bahreyni Toossi MH et al. · 2017
Researchers exposed pregnant mice to cell phone radiation (900-1800 MHz) for 2 hours daily throughout pregnancy, then examined tissue damage in both mothers and their newborns after birth. They found significant oxidative stress (cellular damage from harmful molecules) in the heart, liver, kidney, brain areas of both mothers and offspring. This suggests that prenatal cell phone exposure may cause lasting tissue damage that affects both the pregnant mother and developing baby.
Kim JH et al. · 2017
Researchers exposed C57BL/6 mice to 835 MHz RF-EMF at an SAR of 4.0 W/kg for 12 weeks, then analyzed the hippocampus and brain stem. Several autophagic genes were significantly upregulated only in the hippocampus and not in the brain stem. Transmission electron microscopy revealed an increase in the number of autophagosomes and autolysosomes in the hippocampal neurons of exposed mice.
Chandel S, Kaur S, Singh HP, Batish DR, Kohli RK. · 2017
Researchers exposed onion roots to 2100 MHz cell phone radiation for 1-4 hours and measured cellular damage markers. The exposure triggered increased production of harmful reactive oxygen species (unstable molecules that damage cells) and forced the plants to ramp up their antioxidant defenses. This demonstrates that cell phone frequencies can disrupt normal cellular processes even in plant tissue.
Ghatei N et al. · 2017
Researchers exposed pregnant BALB/c mice to mobile phone jammer radiation at 900 and 1800 MHz on the 19th day of pregnancy. After birth, offspring were divided into four exposure groups and examined at 8-10 weeks of age. Cerebellar expression of bax, bcl-2, p21, and p53 was measured by real-time RT-PCR. Radiation did not change bcl-2 or p53 expression (P>0.05). Radiation decreased bax expression and increased p21 expression compared to controls (P<0.05).
Sharma A, Kesari KK, Saxena VK, Sisodia R. · 2017
Researchers exposed young mice to 10 GHz microwave radiation (similar to some WiFi and cellular frequencies) for 2 hours daily over 15 days and found significant damage to developing brains. The exposed mice showed impaired spatial memory, disrupted brain chemistry, and visible tissue damage in key brain regions including the hippocampus. These effects persisted weeks after exposure ended, suggesting the developing brain is particularly vulnerable to microwave radiation.
Sharma A, Kesari KK, Saxena VK, Sisodia R · 2017
Researchers exposed young mice to 10 GHz microwave radiation (similar to frequencies used in radar and some wireless communications) for 2 hours daily over 15 days. The exposed mice showed impaired spatial memory, brain tissue damage, and disrupted brain chemistry both immediately after exposure and weeks later. This suggests that developing brains may be particularly vulnerable to microwave radiation effects that persist even after exposure ends.
Shirai T et al. · 2017
Researchers exposed pregnant rats and their offspring to eight radiofrequency signals ranging from 800 MHz to 5.2 GHz. The exposure lasted 20 h per day from gestational day 7 through weaning and continued for offspring up to 6 weeks of age. No abnormal findings were observed in the dams, F1 offspring, or F2 offspring across all evaluated parameters. The study concluded that simultaneous whole-body exposure to these frequencies did not show adverse effects on pregnancy or development.
Türedi S, Kerimoğlu G, Mercantepe T, Odacı E. · 2017
Malondialdehyde levels increased in the EMF group compared to both control and sham groups in kidney and bladder tissues, while catalase and glutathione levels decreased. Kidney tissue in the EMF group showed dilatation and vacuolization in tubules, glomerular degeneration, and increased apoptotic cells. Bladder tissue in the EMF group showed degeneration in the transitional epithelium, stromal irregularity, and increased apoptotic cells. Transmission electron microscopy revealed glomerular capillary degeneration with capillary basement membranes in the EMF group.
Sun Y, Zong L, Gao Z, Zhu S, Tong J, Cao Y · 2017
Researchers exposed HL-60 human leukemia cells to continuous 900MHz radiofrequency fields at 120μW/cm² for 4 hours per day over 5 consecutive days. Exposed cells had significantly increased reactive oxygen species and decreased mitochondrial transcription factor A, mtDNA polymerase gamma, mtDNA transcripts, and mtDNA copy number compared to sham-exposed controls. Exposed cells also showed a significant increase in the oxidative damage marker 8-OHdG and a significant decrease in ATP. Pretreating cells with melatonin, a free radical scavenger, reversed the effects seen in RF-exposed cells.
Shahin S, Singh SP, Chaturvedi CM · 2017
Researchers exposed female mice to 1800MHz mobile phone radiation in different modes (standby, dialing, receiving) and found significant damage to reproductive organs and hormone systems. The radiation caused oxidative stress (cellular damage from harmful molecules) and reduced the number of healthy egg follicles, while disrupting key reproductive hormones like estrogen and progesterone. This suggests that mobile phone radiation at typical cellular frequencies may interfere with female fertility through stress-related mechanisms.
Yilmaz A et al. · 2017
Pregnant rats were exposed to 900 MHz EMF for 24 hours a day over 20 days using a digital signal generator placed under the cage. Livers and blood were collected from male and female offspring 60 days after birth for biochemical and histopathological analysis. Liver malondialdehyde levels increased significantly while glutathione levels decreased significantly, and serum ALT and AST levels were significantly elevated. Liver sections showed intense hepatocyte degeneration with cytoplasmic eosinophilic structures, pyknotic nuclei, and fibrosis. The researchers concluded that intrauterine EMF exposure causes harmful liver effects that persist into adulthood.
Andrianome S et al. · 2017
Researchers compared autonomic nervous system activity in 30 self-declared electrohypersensitive participants and 25 matched controls using heart rate variability and skin conductance. The electrohypersensitive group showed more skin conductance responses to auditory stimuli, while short-term heart rate variability did not differ between groups. In a double-blind, counterbalanced session, 10 electrohypersensitive volunteers were exposed to GSM 900, GSM 1800, DECT, and Wi-Fi at 1 V/m. No changes in heart rate variability or skin conductance were observed during or after exposure.
Unknown authors · 2017
Researchers investigated the effect of 1950 MHz Universal Mobile Telecommunication System radiofrequency exposure on Chinese hamster lung fibroblast V79 cells. Genotoxic and cytotoxic effects were measured using the cytokinesis-block micronucleus assay after 20-hour exposures at SAR values of 0.15, 0.3, 0.6, and 1.25 W/kg. Exposure at 0.15 and 0.3 W/kg significantly increased micronucleus frequency without cytotoxicity, while 0.6 and 1.25 W/kg had no effect. Pre-exposure at 1.25 W/kg for 20 hours before MMC treatment significantly reduced micronucleus frequency compared to MMC alone, indicating an adaptive response, whereas pre-exposure at 0.3 W/kg did not.
Su L, Wei X, Xu Z, Chen G · 2017
Researchers exposed neurogenic A172, U251, and SH-SY5Y cells to 1800 MHz RF-EMF at 4.0 W/kg intermittently for 1, 6, or 24 hours. DNA damage was measured by quantifying γH2AX foci, an early marker of DNA double-strand breaks. Cell cycle progression, proliferation, and viability were assessed using flow cytometry, hemocytometer, and cell counting kit-8 assay. Exposure did not significantly induce γH2AX foci formation or cause abnormal cell cycle progression, proliferation, or viability. Prolonged incubation up to 48 hours after exposure also did not significantly affect cellular behavior.
Xu F et al. · 2017
Aslan A, İkinci A, Baş O, Sönmez OF, Kaya H, Odacı E. · 2017
Researchers used three groups of six 21-day-old male rats, including an unexposed control, a sham-exposed group, and a group exposed to 900 MHz EMF for one hour daily from postnatal day 21 to 46. The EMF-exposed group had significantly fewer Purkinje cells than both the control and sham groups. Histopathological examination also showed altered Purkinje cell arrangement and intense cytoplasmic staining in the exposed rats.
Lameth J et al. · 2017
Researchers investigated whether a 2-hour head-only exposure to GSM-1800 MHz could affect a neuroinflammatory reaction triggered by lipopolysaccharide in 2-week-old or adult rats. In developing rats, 24 hours after exposure, cortical interleukin-1β and NOX2 NADPH oxidase transcripts were reduced by 50 to 60% compared with sham-exposed animals. Adult rats showed a 50% reduction in IL1β mRNA but no NOX2 suppression and displayed a significant growth response of microglial cell processes. GSM exposure decreased phosphorylation at two residues on the GluA1 AMPA receptor subunit (serine 831 and 845). The changes in gene expression, microglia, and GluA1 phosphorylation did not persist 72 hours after exposure and were absent without LPS pretreatment.
Gökçek-Saraç Ç et al. · 2017
Rats were exposed to 900 and 2100 MHz RF-EMR for 2 h/day for either 1 week (acute) or 10 weeks (chronic). The study measured hippocampal levels and activity of PKA, CaMKIIα, CREB, and p44/42 MAPK from NMDAR-related signaling pathways using Western blotting and activity assays. Chronic exposure produced significantly higher enzyme levels than acute exposure at both frequencies, and 2100 MHz exposure produced higher levels than 900 MHz in both acute and chronic groups.
Gökçek-Saraç Ç et al. · 2017
Researchers exposed rats to cell phone radiation at 900 MHz and 2100 MHz frequencies for either 1 week or 10 weeks, then examined changes in brain enzymes involved in memory and learning. They found that longer exposure (10 weeks) caused more significant changes than shorter exposure (1 week), and that 2100 MHz radiation (used by 3G networks) had stronger effects than 900 MHz radiation (used by 2G networks). This suggests that both the duration of exposure and the specific frequency matter when it comes to how wireless radiation affects the brain.
Qureshi ST, Memon SA, Abassi AR, Sial MA, Bughio FA. · 2017
Researchers exposed dry chickpea seeds to GSM cell phone radiation at 900 MHz and laptop radiation at 3.31 GHz for 24 and 48 hours. Untreated seeds served as a negative control and gamma rays at 250 Gray served as a positive control. All radiofrequency treatments inhibited seed germination, with the 48-hour laptop exposure showing the strongest negative effect. Mitotic index decreased and abnormality index increased as exposure duration and frequency increased. Cell membrane damage, nuclear membrane damage, and ghost cells were observed only after 48 hours of exposure.
Marjanovic Cermak AM et al. · 2017
Researchers exposed V79 fibroblast cells to 1800 MHz RF radiation for 10, 30, and 60 minutes at a specific absorption rate of 1.6 W/kg to investigate possible links between radiofrequency exposure and oxidative stress. Cell viability remained within normal physiological values regardless of exposure time. An increased level of superoxide radicals was detected after 60-minute exposure, and a significantly higher GSH level was observed immediately after 10-minute exposure, though GSH-Px activity was higher but not significant. Lipid oxidative damage in exposed cell samples was not observed.
Marjanovic Cermak AM et al. · 2017
Researchers exposed human cells to cell phone radiation (1800 MHz) for up to 60 minutes at typical phone power levels. The cells showed signs of oxidative stress, including increased harmful free radicals and elevated cellular defense responses, even without heating effects.
