Ahlers MT, Ammermüller J · 2013
Researchers studied possible non-thermal effects of RF-EMF on retinal ganglion cells in vitro under constant temperature. Mouse retinae were exposed to GSM-900, GSM-1800, and UMTS at SARs of 0, 0.02, 0.2, 2, and 20 W/kg with temperature controlled within ±0.5 to 1°C. Light responses were recorded before, during, and up to 35 minutes after exposure under double-blind conditions. Comparison of sham and actual exposure distance values showed no significant differences, and regression analysis found no consistent SAR dependence. The authors concluded no acute effects on retinal ganglion cell responses at SARs up to 20 W/kg.
Ahlers MT, Ammermüller J. · 2013
German researchers exposed isolated mouse retina cells to mobile phone radiation (GSM-900, GSM-1800, and UMTS) at various power levels while carefully controlling temperature. They found no changes in how these vision-critical cells responded to light stimuli, even at radiation levels 10 times higher than typical phone use. This suggests mobile phone radiation doesn't directly interfere with retinal function under controlled laboratory conditions.
Ketabi N, Mobasheri H, Faraji-Dana R. · 2013
Researchers investigated the effects of ultra high frequency nonionizing electromagnetic fields on the channel activities of the nanopore forming protein OmpF porin. Using the voltage clamp technique on an artificial bilayer, they exposed the pore to electromagnetic fields at 910 to 990 MHz and found that the frequency of channel gating and voltage sensitivity increased, while conductance remained unchanged. No changes in membrane capacitance or permeability were identified, and the energy transferred to nano-environments was estimated to address possible thermal effects.
Kim HS et al. · 2013
Male Sprague-Dawley rats were divided into cage-control, sham-exposed, and RFID-exposed groups and exposed to 915 MHz RFID for 8 h daily, 5 days per week, for 2 or 16 weeks. The whole-body average specific absorption rate was 4 W/kg. FDG-PET images were obtained the day after RFID exposure using micro-PET with a FDG tracer, and the relative cerebral glucose metabolic rate was unchanged in the frontal, temporal and parietal cortexes of exposed rats compared with cage-control and sham-exposed groups.
Kim HS et al. · 2013
Researchers exposed rats to 915 MHz RFID radiation for up to 16 weeks at high intensity levels (4 W/kg SAR) and measured brain glucose metabolism using advanced PET scanning. They found no changes in how the brain processed glucose in any region examined, suggesting this type of radiofrequency exposure didn't alter basic brain energy function. This matters because brain glucose metabolism is a fundamental indicator of neural activity and health.
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
Researchers exposed primary cultured cortical neurons from newborn Sprague-Dawley rats to pulsed 2.45 GHz radiofrequency electromagnetic fields for 10 minutes. Exposure significantly decreased cellular viability and increased apoptotic nuclei, CDK5 activity, the p25 to p35 ratio, and tau phosphorylation at Ser404. CDK5 expression did not change significantly after exposure. A CDK5 inhibitor blocked the exposure-induced decrease in cellular viability and tau hyperphosphorylation but did not significantly block apoptosis.
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
Researchers exposed newborn rat brain cells to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwaves) for just 10 minutes and found significant neuronal damage. The brain cells showed decreased viability, increased cell death, and abnormal protein changes associated with neurodegenerative diseases like Alzheimer's. The study identified a specific cellular pathway (p25/CDK5) that appears to drive this RF-induced brain cell injury.
Gasmelseed A, Yunus J. · 2013
Researchers investigated the interaction of a dipole antenna with a human eye model in the presence of a metamaterial. They used a three-dimensional anatomical model of the human eye with 1.25 mm resolution. The finite difference time domain method with convolutional perfectly matched layer formulation was used. The dipole antenna operated at 900 MHz driven by a modulated Gaussian pulse.
Tong J, Chen S, Liu XM, Hao DM · 2013
Researchers recorded hippocampal CA1 neuron activity in rats exposed to 900 MHz electromagnetic radiation at 10 W/m2 using glass electrode extracellular recording and a polygraph. Discharge frequency of hippocampal CA1 neurons was reduced after exposure, though the change in scale was not obvious. Electromagnetic radiation might change the spontaneous discharge patterns of hippocampus CA1 region neurons, making the explosive discharge pattern increase obviously. The researchers suggested that these changes may lead to a decrease in the ability of learning and memory.
Tong J, Chen S, Liu XM, Hao DM. · 2013
Chinese researchers exposed rats to 900 MHz cell phone radiation and measured brain activity in the hippocampus, which controls learning and memory. The radiation disrupted normal neuron firing patterns and increased abnormal brain cell activity, potentially impairing cognitive function.
Gurbuz N, Sirav B, Colbay M, Yetkin I, Seyhan N. · 2013
Researchers exposed male Wistar albino rats to 1800 MHz or 2100 MHz radiofrequency radiation for 30 min per day, 6 days per week, for either a month or two months. They measured micronucleus frequency in exfoliated bladder cells as an indicator of genotoxic damage. No significant differences in micronucleus frequency were found between any exposed group and its corresponding control group, nor between the two 2100 MHz exposure durations.
Unknown authors · 2013
Researchers assessed potential organ damage using histopathological study. Exposed rats showed significant differences in Olive moment and percent DNA in blood compared to controls. Hyperchromasia was observed in ovaries, and reduced germ cells with cell disorganization were seen in testes with increasing SARs.
Behari J, Nirala JP. · 2013
A SAR measurement system was developed for a brain phantom in a Perspex box. The phantom box volume matched a small rat and was illuminated by a 3G mobile phone at 1718.5 MHz. A moving platform changed the phone's angular position at 2 degrees per minute up to 20 degrees while induced fields were measured. SAR values computed from induced fields were higher than those from induced field measurements alone and varied with angular position, but remained well below human safety criteria. SAR was also measured by temperature rise and compared with the induced-field results, and measurements were repeated in a 10 g phantom in a cubical box for safety criteria comparison.
Gao X, Luo R, Ma B, Wang H, Liu T, Zhang J, Lian Z, Cui X. · 2013
Researchers exposed pregnant rats to 900MHz cell phone radiation for three hours daily throughout pregnancy and found significant brain damage in both mothers and offspring, including swollen brain cells and reduced antioxidant defenses. However, when rats were given vitamin E supplements during pregnancy, the protective antioxidant largely prevented this brain damage. This suggests that EMF exposure during pregnancy can harm developing brains, but certain nutrients may offer protection.
Yang L, Hao D, Wu S, Zhong R, Zeng Y. · 2013
The study numerically evaluated specific absorption rate and temperature rise in SD rat heads exposed to 900 MHz EMF. The digital anatomical model of a SD rat was reconstructed from MRI images and the finite difference time domain method was applied to assess SAR and temperature rise. Whole-body average SAR and localized SAR averaged over 1, 0.5 and 0.05 g mass for different organs and tissues were reported.
Banaceur S, Banasr S, Sakly M, Abdelmelek H · 2013
Researchers studied the effects of 2.4 GHz radiofrequency signals on wildtype mice and triple transgenic mice bred to develop Alzheimer's-like cognitive impairment. Mice were exposed two hours per day during one month at a Specific Absorption Rate of 1.60 W/kg. The researchers reported that radiofrequency exposure improved cognitive behavior in the 3xTg-AD mice.
Baş O et al. · 2013
Researchers exposed pregnant rats to a 900 MHz electromagnetic field on days 13 through 21 of pregnancy, then examined the brains of their female pups on postnatal day 32. Exposure during those prenatal days led to a significant decrease in the number of pyramidal cells in the cornu ammonis of the female rat pups (P<0.05). Histopathological examination also revealed picnotic cells in the cornu ammonis of the exposed female rat pups.
Deshmukh PS et al. · 2013
Deshmukh PS et al. · 2013
The study investigated possible DNA-damaging effects of low-level microwave radiation in the brains of male Fischer rats. Rats were exposed for 30 days at three frequencies: 900, 1800, and 2450 MHz, at specific absorption rates on the order of 10−4 W/kg. DNA damage in brain tissue was assessed using alkaline comet assay after the exposure period. The researchers concluded that low SAR microwave radiation at these frequencies may induce DNA strand breaks in brain tissue.
Haghani M, Shabani M, Moazzami K · 2013
Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.
Lv B, Chen Z, Wu T, Shao Q, Yan D, Ma L, Lu K, Xie Y. · 2013
Eighteen subjects participated in a double-blind, crossover, randomized and counterbalanced experiment including real and sham exposure sessions. Resting-state fMRI signals were collected before and after exposure, with the radiation source placed close to the right ear. After real exposure, decreased ALFF values were found in the left superior temporal gyrus, left middle temporal gyrus, right superior temporal gyrus, right medial frontal gyrus, and right paracentral lobule.
Odacı E et al. · 2013
Researchers exposed pregnant rats to 900 MHz electromagnetic fields for one hour daily between days 13 and 21 of pregnancy, then assessed the female pups' spinal cord tissue and motor behavior. The rotarod test showed a significant increase in motor functions in the EMF group pups (p=0.037), while the open field test found no difference between groups. Pathological changes were observed in the spinal cords of the EMF group pups, and the researchers suggested these changes may have led to the increase in motor activity.
Atasoy HI, Gunal MY, Atasoy P, Elgun S, Bugdayci G · 2013
Researchers exposed male rats to radiofrequency radiation from Wi-Fi devices operating at 2.437 GHz for 24 hours a day for 20 weeks, then examined their testes. The exposed rats showed significant increases in markers indicating DNA damage in the testes compared to controls. Catalase and glutathione peroxidase activity were decreased in the exposed group, which the researchers suggested may have been due to radiofrequency effects on enzyme activity. The researchers said these findings raise questions about the safety of radiofrequency exposure from Wi-Fi Internet access devices for growing organisms of reproductive age, with a potential effect on both fertility and the integrity of germ cells.
Hancı H et al. · 2013
Researchers exposed pregnant rats to 900-MHz EMF during days 13–21 of pregnancy and examined the testicles of their offspring at postnatal day 21. The offspring of exposed mothers showed irregularities in seminiferous tubule basal membrane and epithelium, immature germ cells in the lumen, and a decreased diameter in seminiferous tubules and thickness of epithelium. Apoptotic index, lipid peroxidation, and DNA oxidation were higher in the offspring of exposed mothers than in controls.
Liu C, Duan W, Xu S, Chen C, He M, Zhang L, Yu Z, Zhou Z. · 2013
Researchers exposed a mouse spermatocyte-derived GC-2 cell line to 1800 MHz GSM signals for 24 hours using an intermittent schedule of 5 minutes on and 10 minutes off, at SAR levels of 1 W/kg, 2 W/kg, or 4 W/kg. At a SAR of 4 W/kg, DNA migration in a modified comet assay was significantly increased, and levels of the DNA adduct 8-oxoguanine (8-oxoG) were also increased. No detectable DNA strand breakage was observed by the alkaline comet assay. The increases in DNA damage were accompanied by increases in reactive oxygen species (ROS), and these effects were mitigated by co-treatment with the antioxidant alpha-tocopherol.
