3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 683 studies in Oxidative Stress

The influence of low-frequency magnetic field on plasma antioxidant capacity and heart rate.

Ciejka EB, Goraca A · 2009

Researchers exposed rats to 40 Hz magnetic fields (7 mT strength) for different durations and measured heart rate and antioxidant levels in blood. They found that 14 days of exposure slowed heart rate and changed the body's antioxidant defenses, with effects varying based on daily exposure time (30 vs 60 minutes). The study shows that magnetic field exposure duration affects cardiovascular function and cellular protection systems.

Fifty hertz extremely low-frequency magnetic field exposure elicits redox and trophic response in rat-cortical neurons.

Di Loreto S et al. · 2009

Researchers exposed rat brain cells to 50 Hz magnetic fields and found the exposure improved cell survival and reduced cell death. The magnetic fields also triggered protective antioxidant responses and increased production of proteins that support brain health, suggesting potential protective effects.

Modulator effects of L-carnitine and selenium on wireless devices (2.45 GHz)-induced oxidative stress and electroencephalography records in brain of rat

Naziroğlu M, Gümral N. · 2009

Researchers exposed rats to WiFi-frequency radiation (2.45 GHz) for one hour daily over four weeks. The radiation significantly reduced protective antioxidant vitamins A, C, and E in brain tissue. This suggests wireless devices may deplete the brain's natural defenses against cellular damage.

Effect of radiofrequency electromagnetic field exposure on in vitro models of neurodegenerative disease

Del Vecchio G et al. · 2009

Italian researchers exposed brain cells to cell phone radiation (900 MHz GSM at 1 W/kg SAR) for 144 hours to see if it made them more vulnerable to damage. While the radiation alone didn't harm the cells, it made one type of brain cell significantly more vulnerable to damage from hydrogen peroxide, a common cellular toxin that causes oxidative stress.

Effect of mobile phone exposure on apoptotic glial cells and status of oxidative stress in rat brain

Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Ocak AR · 2009

Researchers exposed rats to 900 MHz cell phone radiation for 2 hours daily over 10 months to study brain cell death (apoptosis) and oxidative stress. Surprisingly, they found reduced cell death and increased antioxidant activity in exposed rats compared to controls. This unexpected finding suggests the brain may activate protective mechanisms in response to chronic low-level radiation exposure.

Enhancement of chemically induced reactive oxygen species production and DNA damage in human SH-SY5Y neuroblastoma cells by 872MHz radiofrequency radiation.

Luukkonen J et al. · 2009

Researchers exposed human brain cells to radiofrequency radiation at 872 MHz (similar to older cell phone frequencies) combined with a chemical that creates cellular damage. They found that continuous wave RF radiation at high intensity (5 W/kg SAR) increased both harmful oxygen molecules and DNA damage compared to the chemical alone. Interestingly, pulsed signals like those used in GSM phones showed no such effects, even at the same power level.

Fifty-gigahertz Microwave exposure effect of radiations on rat brain.

Kesari KK, Behari J. · 2009

Researchers exposed rats to 50-gigahertz microwave radiation (similar to 5G frequencies) for 2 hours daily over 45 days at very low power levels. The study found significant DNA damage in brain cells, along with disrupted antioxidant defenses and decreased protein kinase C activity. These cellular changes suggest that even low-level millimeter wave exposure may affect brain function and cellular health.

Radioprotective effects of honeybee venom (Apismellifera) against 915-MHz microwave radiation-induced DNA damage in wistar rat lymphocytes: in vitro study.

Gajski G, Garaj-Vrhovac V. · 2009

Researchers exposed rat blood cells to 915-MHz microwave radiation (similar to cell phone frequencies) for 30 minutes and found it caused DNA damage. However, when they pre-treated the cells with honeybee venom, the DNA damage was significantly reduced. This suggests that certain natural compounds might help protect our cells from radiofrequency radiation damage.

Reproductive Health464 citations

Mobile phone radiation induces reactive oxygen species production and DNA damage in human spermatozoa in vitro.

De Iuliis GN, Newey RJ, King BV, Aitken RJ. · 2009

Researchers exposed human sperm cells to radiofrequency radiation at the same frequency used by mobile phones (1.8 GHz) for 24 hours in laboratory conditions. They found that as radiation levels increased, sperm became less mobile and viable, while also showing increased DNA damage and harmful cellular stress. This suggests that mobile phone radiation could potentially affect male fertility and even the health of future children.

Oxidative StressNo Effects Found

Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.

Türközer Z, Güler G, Seyhan N · 2008

Researchers exposed guinea pigs to powerful electric fields (the kind found near high-voltage power lines) for 8 hours daily over three days to see if it would damage brain tissue through oxidative stress. They found no statistically significant effects on brain cell damage markers or antioxidant defenses, even at the highest exposure levels tested. While this suggests these particular electric field exposures may not cause measurable brain oxidative damage in the short term, the researchers noted some non-significant trends that warrant further investigation.

Oxidative StressNo Effects Found

Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.

Türközer Z, Güler G, Seyhan N. · 2008

Researchers exposed guinea pigs to 50 Hz electric fields at various strengths (from 2,000 to 5,000 volts per meter) for 8 hours daily over three days, then measured markers of oxidative stress in brain tissue. The study found no statistically significant changes in cellular damage markers or antioxidant enzyme activity, though some non-significant trends were observed. This suggests that short-term exposure to these electric field levels may not cause measurable oxidative stress in brain tissue.

A possible role for extra-cellular ATP in plant responses to high frequency, low amplitude electromagnetic field

Roux D et al. · 2008

French researchers exposed tomato plants to 900 MHz radiofrequency radiation (similar to cell phone frequencies) and found that it rapidly disrupted the plants' cellular energy systems. Within just 30 minutes, the plants' ATP levels (their main energy currency) dropped by 27%, and their overall energy status declined by 18%. This suggests that even low-level EMF exposure can interfere with fundamental cellular processes that keep living organisms functioning properly.

Effects of electromagnetic radiation use on oxidant/antioxidant status and dna turn-over enzyme activities in erythrocytes and heart, kidney, liver, and ovary tissues from rats: possible protective role of Vitamin C.

Devrim E et al. · 2008

Researchers exposed female rats to 900 MHz electromagnetic radiation (the frequency used by cell phones) for 4 weeks and measured markers of cellular damage in their blood and organs. They found significant oxidative stress - essentially cellular damage from harmful molecules called free radicals - in the blood cells and kidneys of exposed rats. When some rats were given vitamin C along with the radiation exposure, it provided partial protection against this cellular damage.

Reproductive Health526 citations

Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study.

Agarwal A, Deepinder F, Sharma RK, Ranga G, Li J. · 2008

Researchers studied 361 men at an infertility clinic and found that cell phone use was linked to declining sperm quality. Men who used phones more than 4 hours daily had significantly worse sperm count, movement, survival, and normal shape compared to non-users. This suggests that the radiofrequency radiation from cell phones may be contributing to male fertility problems.

Effects of Electromagnetic Radiation Use on Oxidant/Antioxidant Status and DNA Turn-over Enzyme Activities in Erythrocytes and Heart, Kidney, Liver, and Ovary Tissues From Rats: Possible Protective Role of Vitamin C

Devrim E et al. · 2008

Researchers exposed female rats to 900 MHz electromagnetic radiation (the frequency used by cell phones) for four weeks and measured oxidative stress markers in blood cells and organs. The EMF exposure increased oxidative stress and tissue damage in red blood cells and kidneys, while vitamin C provided some protection against these effects. This suggests that cell phone radiation may cause cellular damage through oxidative stress pathways.

ELF magnetic therapy and oxidative balance.

Raggi F, Vallesi G, Rufini S, Gizzi S, Ercolani E, Rossi R · 2008

Researchers studied whether magnetic field therapy could reduce cellular damage in 32 healthy people. After treatment, participants showed a 53.8% reduction in oxidative stress markers, with benefits lasting one month. This suggests certain magnetic exposures may protect rather than harm cells.

A 60-Hz sinusoidal magnetic field induces apoptosis of prostate cancer cells through reactive oxygen species.

Koh EK, Ryu BK, Jeong DY, Bang IS, Nam MH, Chae KS · 2008

Researchers exposed prostate cancer cells to 60-Hz magnetic fields (the frequency of household electricity) and found the fields killed cancer cells by increasing harmful molecules called reactive oxygen species. This suggests power-line frequency magnetic fields might potentially be developed as cancer treatments.

Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice.

Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH. · 2008

Researchers exposed mice to magnetic fields and 50 Hz electromagnetic fields (the type from power lines) for 30 days to study health effects. The exposed mice lost weight and showed signs of liver stress, including increased oxidative damage (cellular damage from unstable molecules) and changes in blood chemistry. The study suggests that prolonged exposure to these common electromagnetic fields may disrupt the body's ability to protect itself from cellular damage.

[Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields]

Wu W, Yao K, Wang KJ, Lu DQ, He JL, Xu LH, Sun WJ. · 2008

Chinese researchers exposed human eye lens cells to cell phone radiation (1800 MHz) and found it caused DNA damage and increased harmful free radicals. However, when they added electromagnetic 'noise' fields alongside the phone radiation, this protective interference blocked the cellular damage. The study suggests that certain electromagnetic patterns might counteract the harmful effects of mobile phone radiation on eye cells.

Melatonin reduces oxidative stress induced by chronic exposure of microwave radiation from mobile phones in rat brain.

Sokolovic D et al. · 2008

Researchers exposed rats to mobile phone radiation at levels similar to human exposure for up to 60 days and found significant brain damage from oxidative stress - essentially, cellular damage from harmful molecules. When rats were given melatonin (a natural hormone), it partially protected their brains from this radiation damage. This suggests that mobile phone radiation can harm brain cells through oxidative stress, and that melatonin might offer some protection.

High frequency (900 MHz) low amplitude (5 V m-1) electromagnetic field: a genuine environmental stimulus that affects transcription, translation, calcium and energy charge in tomato.

Roux D et al. · 2008

French researchers exposed tomato plants to 900 MHz electromagnetic fields (the same frequency used by cell phones) at low power levels for just 10 minutes. The plants immediately activated stress response genes and began producing proteins typically associated with injury or environmental damage. The study demonstrates that even brief, low-level radiofrequency exposure can trigger biological stress responses in living organisms.

Proliferation, oxidative stress and cell death in cells exposed to 872 MHz radiofrequency radiation and oxidants. Radiat.

Höytö A, Luukkonen J, Juutilainen J, Naarala J. · 2008

Researchers exposed human brain cells and mouse cells to cell phone-like radiation at 5 W/kg (10 times higher than typical phone use) for up to 24 hours. The radiation alone caused no harmful effects, but when cells were already stressed by chemical toxins, the radiation made some cellular damage worse. This suggests radiofrequency radiation might amplify harm in cells that are already under stress from other sources.

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