Unknown authors · 2021
Pregnant Wistar albino rats were exposed to pulsed 2.45 GHz microwave radiation at 2.8 mW/cm² for 2 hours daily throughout pregnancy. Male offspring were not exposed after birth and were examined at 75 days of age. Exposed adult rats showed irregular seminiferous tubules, degenerated germ cells, reduced tubule diameter and epithelial height, and increased interstitial space. Exposed rats also had more vacuoles, altered organelles, necrotizing cells, empty spaces between Sertoli and germ cells, and increased lipid droplets in Leydig cells. Fluoro Jade-C and superoxide dismutase 2 positivity were increased in exposed rats.
Vafaei S, Motejaded F, Ebrahimzadeh-Bideskan A · 2020
Delavarifar S et al. · 2020
Researchers exposed 30 adult male Balb/c mice to 2.4 GHz Wi-Fi radiation or sham exposure, with some mice treated with busulfan to induce oligospermia. Low power density Wi-Fi radiation significantly increased sperm concentration in healthy mice and showed greater increase in oligospermic mice with higher exposure.
Unknown authors · 2020
Researchers surveyed pregnant women at a hospital in northern Iran about their cell phone use and attitudes. Most participants used cell phones, with only 3.1% being non-users and 6.052% not using during the first trimester. About 64.3% believed cell phones pose risks to the fetus, and awareness was linked to education, residency, and employment.
Unknown authors · 2020
Researchers found that exposure to the cell phone alters the growth and maturation rate of murine ovarian follicle. This effect occurred through changes in the expression of MMP-2 and MMP-9 genes.
Unknown authors · 2020
The study aimed to investigate the effects of 900 MHz EMF exposure (60 min/day for 28 days) on rat testis and to determine whether thymoquinone (10 mg/kg/day) reduced the deleterious effect. EMF exposure significantly decreased primary spermatocytes, spermatids, Leydig cells, serum testosterone, and testis weight compared to controls. Thymoquinone treatment significantly increased primary spermatocyte numbers compared to EMF alone.
Unknown authors · 2020
Pregnant mice were exposed to Wi-Fi signal (2.4 GHz) for 2 and 4 hours. Placenta tissues were examined for MDA and SOD levels, and gene expression of SOD, CDKNA1, GADD45a, Bax, and Bcl-2 was measured by real-time PCR, while apoptosis was assessed using TUNEL assay. MDA and SOD levels significantly increased in exposed groups (P-value<0.05), and SOD mRNA expression also significantly increased. CDKN1A and GADD45a gene expression increased in exposed groups (P-value<0.05), and apoptosis increased as shown by quantitative PCR and TUNEL assay (P-value<0.05).
Unknown authors · 2020
The study used 32 adult male BALB/c mice divided into four groups: control, melatonin (2 mg/kg intraperitoneally for 30 consecutive days), RF-EMR exposure (900 MHz, 100 to 300 MT, 54 to 160 W/m, 4 hours per day whole body), and melatonin plus RF-EMR. After exposure, researchers evaluated oxidative stress parameters, testosterone level, and testicular histopathology. RF-EMR exposure induced oxidative stress, testicular tissue damage, and decreased testosterone. Melatonin treatment improved oxidative stress parameters (MDA and GSH), testis injury score, increased germinal epithelial thickness and seminiferous tubule diameter, and decreased testosterone in EMR-exposed mice, with significant differences (p < .05).
Esmailzadeh S et al. · 2019
Researchers conducted a case-control study of 462 women with infertility and 471 controls between 2014 and 2016. Distance from high voltage power lines (240–400 kV) to each residence was measured using GIS and Google Earth. Women living within 500 meters had an odds ratio of 4.14 (95% CI 2.61 to 6.57) for infertility compared with those living beyond 1000 meters, and the adjusted odds ratio was 4.44 (95% CI 2.77 to 7.11).
Unknown authors · 2019
The study aimed to examine microtubule polymerization and structural behavior in brain and sperm of rats exposed to a 50 Hz extremely low-frequency electromagnetic field. Twenties adult male rats were randomly divided into control and experimental groups, and semen and brain samples were split into four groups for microtubule polymerization analysis. There were no significant differences in testosterone, corticosterone, anxiety behavior, or sperm morphology between groups, but sperm viability, total motility, and progressive motility were significantly higher after exposure. Microtubule polymerization in sperm was significantly higher in the exposed group, and the secondary and tertiary structures of tubulin were significantly affected in both brain and sperm.
Unknown authors · 2019
Researchers used data from 55,507 pregnant women across four birth cohorts in Denmark, the Netherlands, Spain, and South Korea to examine associations between maternal cell-phone use and pregnancy outcomes. Exposure was categorized based on self-reported daily call frequency into none, low, intermediate, or high groups. The intermediate exposure group showed a higher risk of lower gestational age (hazard ratio 1.04, 95% CI 1.01–1.07), and exposure-response trends were seen for shorter pregnancy duration and preterm birth. No associations were found with fetal growth or birth weight measures.
Unknown authors · 2019
Researchers exposed honey bee queen larvae to radiation from a common mobile phone device (GSM band at 900 MHz) during all stages of pre-adult development including pupation. After 14 days of exposure, hatching of adult queens was assessed and mating success after a further 11 days. Mobile phone radiation significantly reduced the hatching ratio but not the mating success. When treated queens successfully mated, colony development was not adversely affected.
Unknown authors · 2019
Unknown authors · 2019
Twenty-four Wistar albino rats were randomly divided into four groups: control, EMF, luteolin, and EMF + luteolin. EMF exposure reduced Leydig cells, primary spermatocytes, and spermatids, increased SOD activity, and decreased testis wet weight and serum testosterone. Luteolin treatment increased those cell counts, restored testis weight and testosterone, and decreased SOD activity compared with EMF alone.
Unknown authors · 2019
Researchers exposed rats to 900 MHz EMF for 2 hours daily over 8 weeks and measured effects on male reproductive parameters. EMF exposure significantly decreased sperm count, viability and motility and increased sperm deformities. EMF-exposed rats showed significant reductions in serum inhibin B and testosterone along with elevated activin A, follicle-stimulating hormone, luteinizing hormone and estradiol concentrations. Testicular StAR protein, c-kit mRNA expression, and activities of 3β- and 17β-hydroxysteroid dehydrogenases were significantly attenuated after EMF exposure. Spermine administered at 2.5 mg/Kg/day intraperitoneally for 8 weeks prevented EMF-induced alterations in sperm and hormone profiles, StAR and c-kit expression, and androgenic enzyme activities.
Unknown authors · 2019
Researchers isolated preantral follicles from 16 to 18 day-old NMRI mice and divided them into control and cell phone-exposed groups, culturing them for 12 days. Follicle diameters and rates of survival, antrum formation, ovulation, and metaphase II oocytes were all significantly lower in the cell phone-exposed group. Antioxidant enzyme activities (SOD, GPX, and CAT) and total antioxidant capacity were significantly lower in exposed follicles, while MDA levels were significantly higher.
Unknown authors · 2019
Alkis MS, Akdag MZ, Dasdag S, Yegin K, Akpolat V · 2019
Researchers exposed rats to 900, 1800, and 2100 MHz radiofrequency radiation for 2 hours daily over 6 months. Exposure increased oxidative stress markers including TOS, OSI, MDA, and 8-OHdG, while decreasing total antioxidant status. DNA damage measured by comet assay showed higher tail intensities in exposed groups.
Unknown authors · 2018
Unknown authors · 2018
Qin F et al. · 2018
Researchers exposed male mice to 1800 MHz radiofrequency fields at 40 μW/cm2 and 0.0553 W/Kg SAR for 2 hours per day over 32 days. The exposure significantly reduced testosterone levels and altered the expression of steroidogenic genes Star, P450scc, P450c17, and 3β-Hsd in testicular tissue. RF exposure also significantly reduced the regulatory protein CaMKI/RORα, and similar effects were observed in cultured primary Leydig cells exposed in vitro. The CaMK inhibitor KN-93 blocked all these observations, and ionomycin reversed the RF-induced down-regulation of intracellular calcium and CaMKI/RORα expression.
Unknown authors · 2018
Twelve-week old male mice were exposed to 2.45 GHz microwave radiation at 0.0248 mW/cm2 power density and 0.0146 W/kg SAR for two hours daily over 15, 30, and 60 days. Researchers evaluated testicular histology, serum testosterone, ROS, NO, MDA, antioxidant enzymes, and apoptotic protein expression. Exposure induced testicular redox imbalance that enhanced apoptosis via a p53 dependent Bax-caspase-3 pathway with severity increasing with exposure duration.
Unknown authors · 2018
Male albino Wistar rats were exposed to 900 MHz radiation for 1 hour per day at a power density of 146.60 µW/cm2 from a mobile phone for 28 days. MDA concentration was increased but TA levels and GST activity were not different in the exposed group compared to controls. Sperm motility was slightly reduced and percentage of abnormal sperm was significantly elevated in the exposed group. Loss of germ cells, particularly spermatocytes and spermatids, was found in the testes of exposed rats, and testes caspase-3 activity was slightly elevated.
Unknown authors · 2018
Mice were exposed to 2.45 GHz microwave radiation at a power density of 0.25 mW/cm2 and SAR of 0.09 W/kg for 2 hours per day over 30 days. Exposure significantly increased catalase, malondialdehyde, and reactive oxygen species while decreasing glutathione peroxidase, testosterone, and superoxide dismutase levels. Flow cytometry revealed micronuclei formation in the blood of exposed mice, and histopathological changes were observed in seminiferous tubules.
Hancı H, Kerimoğlu G, Mercantepe T, Odacı E · 2018
Twenty-four Sprague Dawley rats aged 21 days were randomly divided into three groups, and the EMF group rats were exposed to continuous 900-MHz EMF for 1 h each day during adolescence. The results showed that changes may occur in morphology and oxidative stress biomarkers in the rat testis after such exposure.
