6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 152 studies in Sleep & Circadian Rhythm

Therapeutic approaches of melatonin in microwave radiations-induced oxidative stress-mediated toxicity on male fertility pattern of Wistar rats

Meena R, Kumari K, Kumar J, Rajamani P, Verma HN, Kesari KK. · 2014

Researchers divided 70-day-old male Wistar rats into four groups: sham exposed, melatonin treated, microwave exposed, and microwave plus melatonin treated. Exposure took place in Plexiglas cages for 2 hours a day for 45 days at a power density of 0.21 mW/cm2 and a SAR of 0.14 W/Kg. Melatonin was associated with a significant increase in testicular LDH-X and decreased levels of MDA and ROS in the testes. The researchers concluded that melatonin has strong antioxidative potential against microwave-induced oxidative stress mediated DNA damage in testicular cells.

Does Exposure to a Radiofrequency Electromagnetic Field Modify Thermal Preference in Juvenile Rats?

Pelletier A et al. · 2014

Researchers recorded thermal preference and sleep in 18 young male Wistar rats, with nine exposed to a low-intensity RF-EMF at 900 MHz and nine serving as non-exposed controls. During the light period, exposed rats preferred to sleep at an air temperature of 31°C while controls preferred 28°C. During the dark period, no significant differences between groups were found.

Cancer & Tumors
Not an original health-effects study

New Zealand adolescents' cellphone and cordless phone user-habits: are they at increased risk of brain tumours already? A cross-sectional study.

Redmayne M · 2013

The cross-sectional study recruited 373 Year 7 and 8 students with a mean age of 12.3 years from the Wellington region of New Zealand. Participants completed a questionnaire and measured their normal body-to-phone texting distances. Both cellphones and cordless phones were used by approximately 90% of students. A third of participants had already used a cordless phone for ≥ 7 years. High cellphone use was related to cellphone location at night, being woken regularly, and being tired at school.

Symptoms & SensitivityNo Effects Found

Subjective symptoms related to GSM radiation from mobile phone base stations: a cross-sectional study.

Gómez-Perretta C, Navarro EA, Segura J, Portolés M. · 2013

Researchers re-analyzed data from a 2003 study on health symptoms related to microwave exposure from mobile phone base stations. They used binary logistic regression with bootstrapping to model symptoms as a function of exposure. The symptoms most related to exposure were lack of appetite, lack of concentration, irritability, and trouble sleeping. Concerns about base stations were strongly related to trouble sleeping. The exposure variable remained statistically significant in multivariate analysis.

Sleep & Circadian RhythmNo Effects Found

Effects of electromagnetic fields emitted from W-CDMA-like mobile phones on sleep in humans.

Nakatani-Enomoto S et al. · 2013

Researchers exposed 19 volunteers to real or sham electromagnetic fields for 3 h before sleep on three consecutive days in a double-blind design. No significant differences were found in subjective feelings, sleep stage percentages, or EEG power spectra between real and sham exposures. The researchers concluded that the exposure had no detectable effects on human sleep.

Association between Problematic Cellular Phone Use and Suicide: The Moderating Effect of Family Function and Depression.

Wang PW, Liu TL, Ko CH, Lin HC, Huang MF, Yeh YC, Yen CF. · 2013

The study examined the association between problematic CPU and suicidal ideation and attempts in 5051 adolescents. About 10.54% of adolescents had problematic CPU, with suicidal ideation rates of 23.50% versus 11.76% and attempt rates of 13.70% versus 5.45%. Family function, but not depression, had a moderating effect on the association between problematic CPU and suicidal ideation and attempt.

Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin

Aynali G, Nazıroğlu M, Celik O, Doğan M, Yarıktaş M, Yasan H · 2013

Thirty-two male rats were divided into four groups, including a melatonin-treated group receiving 10 mg/kg/day. Rats in the exposure groups received 2.45 GHz radiation for 60 minutes daily for 28 days. Radiation exposure raised lipid peroxidation levels compared with controls. Melatonin treatment lowered lipid peroxidation and increased glutathione peroxidase activity. Reduced glutathione levels did not differ among groups.

Reduction of pain thresholds in fibromyalgia after very low-intensity magnetic stimulation: a double-blinded, randomized placebo-controlled clinical trial.

Maestú C et al. · 2013

A double-blinded, placebo-controlled clinical trial was performed at Sagrado Corazón Hospital in Seville, Spain, enrolling female fibromyalgia patients aged 22 to 50 years. The stimulation group received 8 Hz pulsed magnetic fields of very low intensity, while the sham group underwent the same protocol without stimulation. The stimulation group showed statistically significant improvement in somatosensory pain thresholds, ability to perform daily activities, perceived chronic pain, and sleep quality compared with the control group. Pain thresholds improved after the first session, while the other measures improved after the sixth week. No significant differences were found for depression, fatigue, headache severity, or serotonin levels, and no adverse effects were reported.

The relationship between adolescents' well-being and their wireless phone use: a cross-sectional study

Redmayne M, Smith E, and Abramson MJ · 2013

More frequent cellphone and cordless phone calls were associated with higher odds of headaches, wired headsets with tinnitus, wireless headsets with headache, feeling down or depressed, and waking at night, and being woken by a cellphone at night was strongly linked to daytime tiredness. The study reported that 36% of tested associations were statistically significant, more than the 5% expected by chance, and several showed dose-dependent patterns.

Non-thermal continuous and modulated electromagnetic radiation fields effects on sleep EEG of rats

Mohammed HS, Fahmy HM, Radwah NM, Elsayed AA · 2013

Researchers investigated the effect of chronic low-level non-thermal electromagnetic radiation on sleep EEG in rats. They used two types of radiation fields: 900 MHz unmodulated and 900 MHz modulated at 8 and 16 Hz, with exposure for one month at one hour per day. EEG power spectral analyses revealed that REM sleep was more susceptible to modulated radiofrequency radiation than slow wave sleep. The latency of REM sleep increased due to radiation exposure, indicating a change in the ultradian rhythm of normal sleep cycles. The authors concluded that exposure to electromagnetic radiation in awake animals can alter subsequent sleep structure and suggested cumulative irreversible effects.

Stimulation of the brain with radiofrequency electromagnetic field pulses affects sleep-dependent performance improvement.

Lustenberger C et al. · 2013

Sixteen male subjects completed two experimental nights, one with all-night pulsed radiofrequency electromagnetic field exposure at 0.25–0.8 Hz. Sleep efficiency exceeded 90 percent in both conditions. Slow-wave activity increased during pulsed exposure compared to sham toward the end of the sleep period. Spindle activity did not change. Motor sequence task improvement was reduced by 20.1 percent during exposure versus sham.

Effects of chronic exposure to radiofrequency electromagnetic fields on energy balance in developing rats

Pelletier A et al. · 2013

Researchers examined the effects of chronic RF-EMF exposure (900 MHz, 1 V m(-1)) on the main functions involved in body energy homeostasis, including feeding behaviour, sleep, and thermoregulatory processes. Thirteen juvenile male Wistar rats were exposed to continuous RF-EMF for 5 weeks and compared with 11 non-exposed animals. The frequency of rapid eye movement sleep episodes was greater in the exposed group independently of ambient temperature, with increases of 42.1% at 24 °C and 31.6% at 31 °C. Exposure also increased daytime food intake, and the researchers concluded that RF-EMF exposure can induce energy-saving processes without strongly disturbing the overall sleep pattern.

Sleep & Circadian RhythmNo Effects Found

Use of wireless phones and serum β-trace protein in randomly recruited persons aged 18-65 years: a cross-sectional study

Söderqvist F, Carlberg M, Zetterberg H, Hardell L · 2012

Three hundred and fourteen people aged 18-65 years were recruited from Örebro, Sweden, using the population registry. They used linear regression analyses adjusted for covariates to examine associations between serum β-trace protein and short- and long-term wireless phone use. Overall, no statistically significant association was found, but a negative association emerged for long-term use in the 18-30 year age group.

Radio FrequencyNo Effects Found

Is there any exposure from a mobile phone in stand-by mode?

Mild KH, Andersen JB, Pedersen GF. · 2012

Several earlier studies used a GSM phone in stand-by mode as an exposure source and reported effects on sleep and testicular function. The authors explain that in stand-by mode the phone is only active during periodic location updates set by the network operator. Typical updates occur every 2 to 5 hours, and between updates the phone acts as a passive receiver with no microwave emission. They conclude that exposure in stand-by mode can be considered negligible.

Sleep & Circadian RhythmNo Effects Found

Exposure to radiofrequency electromagnetic fields and sleep quality: a prospective cohort study.

Mohler E et al. · 2012

Researchers conducted a prospective cohort study with 955 participants aged 30 to 60 years to investigate whether sleep quality is affected by mobile phone use or other RF-EMF sources. Sleep quality and daytime sleepiness were assessed using standardized questionnaires at baseline in May 2008 and follow-up in May 2009. In longitudinal analyses, neither operator-recorded nor self-reported mobile phone use was associated with sleep disturbances or daytime sleepiness.

Accidents and close call situations connected to the use of mobile phones.

Korpinen L, Pääkkönen R. · 2012

Researchers conducted a cross-sectional study by mailing a questionnaire to 15,000 working-age Finns and analyzed 6121 responses using logistic regression models. During leisure time, 13.7% of respondents reported close call situations and 2.4% reported accidents in which mobile phone use had a partial effect. At work, the corresponding percentages were 4.5% for close calls and 0.4% for accidents. Men, younger people, and employed individuals tended to have more mobile-phone-related incidents, and sleep disturbances with minor aches were linked to a slight increase in such incidents.

Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices.

Oksay T, Naziroğlu M, Doğan S, Güzel A, Gümral N, Koşar PA. · 2012

Thirty-two rats were equally divided into four groups: cage control, sham control, 2.45-GHz EMR exposure, and 2.45-GHz EMR plus melatonin. Rats in the EMR groups were exposed to 2.45-GHz EMR for 60 minutes per day for 30 days. EMR exposure increased lipid peroxidation and decreased vitamins A and E in the testis. Melatonin treatment prevented the rise in lipid peroxidation and the drop in vitamin E.

Pathophysiology of microwave radiation: effect on rat brain.

Kesari KK, Kumar S, Behari J. · 2012

Researchers exposed Wistar rats to 2.45 GHz frequency microwave radiation for 2 h a day for 45 days, with a whole body specific absorption rate estimated to be 0.14 W/kg. Pineal melatonin levels were significantly lower in the exposed group compared with the sham-exposed group. Creatine kinase, caspase 3, and calcium ion concentration were all significantly higher in the whole brain of the exposed animals.

The effect of melatonin on body mass and behaviour of rats during an exposure to microwave radiation from mobile phone.

Sokolovic D et al. · 2012

Researchers exposed Wistar rats to microwave radiation for 4 hours per day and tested whether melatonin could counter any resulting changes in body mass or behaviour. A significant body mass reduction was noted in animals exposed to MW radiation when compared to controls after 20, 40 and 60 days (p<0.001). Exposed animals showed anxiety-related behaviour described as agitation and irritability after 10 days of exposure, and these changes became less noticeable after the radiation source was removed. Melatonin pretreatment significantly increased body weight in irradiated rats compared to irradiated rats without melatonin after 20 days (p<0.05), and melatonin administration caused a decrease in stress-induced behaviour.

Sleep EEG alterations: effects of pulsed magnetic fields versus pulse‐modulated radio frequency electromagnetic fields

Schmid MR et al. · 2012

Twenty-five young healthy men took part in a randomized double-blind crossover design, exposed at weekly intervals to different conditions for 30 minutes before sleep. The conditions were a 2-Hz pulse-modulated radio frequency field, a 2-Hz pulsed magnetic field, and sham. Radio frequency exposure increased electroencephalogram power in the spindle frequency range. Delta and theta activity during non-rapid eye movement sleep, and alpha and delta activity during rapid eye movement sleep, were affected following both exposure conditions. No effect on sleep architecture and no clear impact of exposure on cognition was observed.

Sleep EEG alterations: effects of different pulse-modulated radio frequency electromagnetic fields.

Schmid MR et al. · 2012

Thirty young healthy men were exposed, at weekly intervals, for 30 minutes directly before an 8-hour sleep period to a 900-MHz RF EMF pulse-modulated at 14 Hz, at 217 Hz, or to a sham control. EEG power in the spindle frequency range was increased during non-rapid eye movement sleep after the 14-Hz pulse-modulated condition, while a similar but non-significant increase was also observed after the 217-Hz condition. No clear exposure-related effects on cognitive performance were seen, and the exposure-induced effect showed considerable individual variability.

Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat.

Nazıroğlu M et al. · 2012

Researchers divided rats into four groups: a cage control, a sham control, a group exposed to 2.45 GHz electromagnetic radiation, and a group exposed to the same radiation while also receiving melatonin. The radiation-exposed groups received that exposure for 60 minutes per day for 30 days, after which brain cortex and dorsal root ganglion samples and EEG recordings were collected. Lipid peroxidation, cell viability, and cytosolic calcium values in dorsal root ganglion neurons were higher in the radiation-only group than in the control groups. The melatonin-plus-radiation group showed lower EEG spike numbers and higher brain cortex vitamin E concentration compared with the radiation-only group.

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