6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 653 studies (Cell Studies)

Effects of 940 MHz EMF on Luciferase Solution: Structure, Function, and Dielectric Studies.

Sefidbakht Y et al. · 2013

Researchers used a rectangular waveguide system to expose luciferase to 940 MHz electromagnetic fields. Exposed luciferase showed significantly higher activity and smaller hydrodynamic radii than unexposed samples. Exposed samples also had less tendency to form aggregates. Dielectric measurements indicated changes related to disaggregation potency.

Cardiovascular310 citations

The relationship between cell phone use, physical and sedentary activity, and cardiorespiratory fitness in a sample of U.S. college students.

Lepp A, Barkley JE, Sanders GJ, Rebold M, Gates P. · 2013

Participants were interviewed about physical activity and cell phone use, had body composition and self-efficacy assessed, and completed a progressive treadmill test to measure peak oxygen consumption. Hierarchical regression was used to assess the relationship between cell phone use and cardiorespiratory fitness after controlling for sex, self-efficacy, and percent body fat. Cell phone use was significantly and negatively related to cardiorespiratory fitness independent of sex, self-efficacy, and percent body fat.

Effects of olive leave extract on metabolic disorders and oxidative stress induced by 2.45 GHz WIFI signals.

Salah MB, Abdelmelek H, Abderraba M. · 2013

Researchers exposed rats to 2.45 GHz RF for 1 hour daily over 21 consecutive days, which induced a diabetes-like status. RF exposure decreased glutathione peroxidase, catalase, superoxide dismutase, and thiol group activities in liver and kidneys, while increasing malondialdehyde concentration in both organs. Olive leaf extract at 100 mg/kg prevented glucose metabolism disruption, restored antioxidant enzyme activities and thiol groups in liver and kidneys, and reduced elevated malondialdehyde in liver but not in kidneys.

Interference of vitamin E on the brain tissue damage by electromagnetic radiation of cell phone in pregnant and fetal rats

Gao X, Luo R, Ma B, Wang H, Liu T, Zhang J, Lian Z, Cui X · 2013

Radiation exposure decreased SOD and GSH-Px activity and increased MDA levels in both pregnant and fetal rats, and caused mitochondrial swelling, edema, and chromatin condensation in fetal brain tissue. Vitamin E supplementation reversed these changes in a dose-dependent manner, with all three doses increasing SOD and GSH-Px in fetal rats, and middle and high doses decreasing MDA in fetal rats and high dose doing so in pregnant rats.

Oxidative and genotoxic effects of 900 MHz electromagnetic fields in the earthworm Eisenia fetida.

Tkalec M, Stambuk A, Srut M, Malarić K, Klobučar GI. · 2013

Researchers exposed earthworms (Eisenia fetida) in vivo to 900 MHz radiofrequency electromagnetic fields at field levels of 10, 23, 41 and 120 V m(-1) for 2 hours using a Gigahertz Transversal Electromagnetic (GTEM) cell. All exposure treatments induced significant genotoxic effects in earthworm coelomocytes, as detected by the Comet assay. The results also indicated enhanced catalase and glutathione reductase activity, as well as lipid and protein oxidative damage. Antioxidant responses and the potential for damage to lipids, proteins, and DNA differed depending on field level, field modulation, and duration of exposure.

Overproduction of free radical species in embryonal cells exposed to low intensity radiofrequency radiation

Burlaka A et al. · 2013

Researchers exposed Japanese quail embryos in ovo to GSM 900 MHz radiofrequency radiation at 0.25 µW/cm2 for 158 to 360 hours on a discontinuous schedule. The exposure produced a significant persistent overproduction of superoxide and nitrogen oxide in embryo cells throughout the analysis period. Exposed embryo cells also showed significantly increased levels of TBARS and 8-oxo-dG alongside significantly decreased superoxide dismutase and catalase activities.

Changes of dendritic spine density and morphology in the superficial layers of the medial entorhinal cortex induced by extremely low-frequency magnetic field exposure.

Xiong J, He C, Li C, Tan G, Li J, Yu Z, Hu Z, Chen F. · 2013

Researchers exposed rats to a 0.5 mT 50 Hz extremely low-frequency magnetic field for 14 and 28 days and then used Golgi staining to examine dendritic spines in the superficial layers of the medial entorhinal cortex. Exposure reduced spine density in stellate neurons and the basal dendrites of pyramidal neurons at both time points, largely due to loss of thin and branched spines. Reduced spine density in the apical dendrites of pyramidal neurons was only observed at 28 days, reflecting distinct vulnerability of spines in the apical and basal dendrites.

Response of Hippocampal Neurons and Glial Cells to Alternating Magnetic Field in Gerbils Submitted to Global Cerebral Ischemia.

Rauš S et al. · 2013

Researchers studied whether exposure to an extremely low-frequency magnetic field (ELF-MF, 50 Hz) affects postischemic damage in the hippocampus of Mongolian gerbils. After 10-min bilateral carotid occlusion, gerbils were continuously exposed to ELF-MF at an average magnetic induction of 0.5 mT for 7 days, with outcomes assessed on the seventh and 14th days after reperfusion. Ischemic gerbils exposed to ELF-MF had significantly lower cell loss and greater astrocyte and microglial responses compared with ischemic gerbils without exposure on the seventh day after reperfusion. By the 14th day after reperfusion, differences in the measured parameters were low and insignificant.

50 Hz Electromagnetic Field Produced Changes in FTIR Spectroscopy Associated with Mitochondrial Transmembrane Potential Reduction in Neuronal-Like SH-SY5Y Cells.

Calabrò E et al. · 2013

Researchers used SH-SY5Y neuroblastoma cells as an experimental model to study the effects of a 50 Hz electromagnetic field in the range from 50 µT to 1.4 mT. Fourier transform infrared spectroscopy analysis showed a reduction in intensity of the amide A band and a slight increase of vibration bands corresponding to methylene groups. Exposure to a 50 Hz electromagnetic field higher than 0.8 mT was associated with a significant reduction of cell viability and reduced mitochondrial transmembrane potential.

The anti-tumor effect of A3 adenosine receptors is potentiated by pulsed electromagnetic fields in cultured neural cancer cells

Unknown authors · 2012

The study evaluated whether PEMF exposure potentiated the anti-tumor effect of A3ARs in PC12 rat adrenal pheochromocytoma and U87MG human glioblastoma cell lines compared with rat cortical neurons. PEMF exposure up-regulated A2A and A3ARs that are well coupled to adenylate cyclase activity and cAMP production. Activation of A2A and A3ARs decreased NF-kB levels in tumor cells, while only A3ARs increased p53 expression. A3AR stimulation inhibited tumor cell proliferation, increased cytotoxicity and apoptosis in PC12 and U87MG cells but not in cortical neurons. The A3AR agonist effect was enhanced by PEMFs and blocked by a selective antagonist, showing that PEMF exposure significantly increases the anti-tumor effect modulated by A3ARs.

Biologic effects of SMF and paclitaxel on K562 human leukemia cells

Unknown authors · 2012

Researchers evaluated the ability of 8.8 mT static magnetic fields to enhance paclitaxel action against K562 leukemia cells. They analyzed cell proliferation, cell cycle distribution, DNA damage, and ultrastructural changes after exposure to paclitaxel with or without the magnetic field. The combination reduced the effective paclitaxel concentration from 50 to 10 ng/ml, caused G2 phase arrest, and this arrest correlated with DNA damage. Microscopy showed ultrastructural alterations including holes, protuberances, and increased cytoplasmic vacuoles in the combination group.

DNA & Genetic DamageNo Effects Found

Terahertz electromagnetic fields (0.106 THz) do not induce manifest genomic damage in vitro

Hintzsche H et al. · 2012

Researchers exposed cells to terahertz electromagnetic fields for 2 h, 8 h, and 24 h at power intensities from 0.04 mW/cm2 to 2 mW/cm2. Genomic damage was assessed using the comet assay for DNA strand breaks and alkali-labile sites and the micronucleus assay for chromosomal damage. No DNA strand breaks or alkali-labile sites were detected after exposure. The fields also did not induce micronucleus formation, indicating no chromosomal damage.

Mobile Phone Electromagnetic Waves and Its Effect on Human Ejaculated Semen: An in vitro Study

Unknown authors · 2012

Researchers studied the effect of electromagnetic radiation on ejaculated human semen samples. Exposed samples showed a significant decrease in sperm motility and viability and an increase in reactive oxygen species and DNA fragmentation index compared to unexposed samples. The researchers concluded that mobile phone electromagnetic waves lead to oxidative stress in human semen and cause changes in DNA fragmentation.

Assessing LINE-1 retrotransposition activity in neuroblastoma cells exposed to extremely low-frequency pulsed magnetic fields

Unknown authors · 2012

Researchers used an in vitro retrotransposition assay on human neuroblastoma BE(2) cells exposed for 48h to 1mT, 50Hz PMF or sham exposure. They also measured γ-H2AX foci as a marker of DNA DSB in both exposed and sham-exposed samples. PMF-exposed cells had a lower number of both retrotransposition events and DNA DSB compared with sham-exposed samples.

Radio FrequencyNo Effects Found

A forecasting method to reduce estimation bias in self-reported cell phone data.

Redmayne M, Smith E, Abramson MJ. · 2012

Researchers developed a Bayesian forecasting method to reduce estimation bias in recalled cell phone use. Participants recalled their SMS texting and provided actual use data from their provider as the gold standard. The Bayesian method substantially reduced estimation bias that arises from large random error in recall. The method can lead to more accurate relative risk calculations for mid-to-heavy users when applied to suitable data.

Oxidative StressNo Effects Found

Biological indicators in response to radiofrequency/microwave exposure

Marjanović AM, Pavičić I, Trošić I · 2012

Radiation from man-made sources has exceeded natural radiation due to rapid technological progress. There is general concern about appliances using radiofrequency and microwave radiation, especially mobile communication systems. The authors identify reactive oxygen species generation as a plausible mechanism for radiofrequency and microwave radiation effects. Excessive reactive oxygen species production can overload antioxidant defenses and lead to cellular damage with potential for disease development. Further research is needed to understand the exact mechanism and consequences.

Reproductive HealthNo Effects Found

The influence of 1800 MHz GSM-like signals on blood chemistry and oxidative stress in non-pregnant and pregnant rabbits.

Kismali G, Ozgur E, Guler G, Akcay A, Sel T, Seyhan N. · 2012

Researchers exposed 13-month-old New Zealand White rabbits to whole-body 1800 MHz GSM-like radiofrequency radiation for 15 minutes per day for seven days. The study used four groups: non-pregnant controls, non-pregnant exposed, pregnant controls, and pregnant exposed. Lipid peroxidation measured as malondialdehyde levels did not change after exposure. Several blood chemistry parameters including cholesterol, total protein, albumin, uric acid, creatinine, creatine kinase, and CK-MB changed due to both pregnancy and RFR exposure. No indication of oxidative stress was detected in pregnant rabbits, though CK-MB and CK increases were described as remarkable.

Microwave electromagnetic field regulates gene expression in T-lymphoblastoid leukemia CCRF-CEM cell line exposed to 900 MHz.

Trivino Pardo JC, Grimaldi S, Taranta M, Naldi I, Cinti C. · 2012

Researchers cultured acute T-lymphoblastoid leukemia cells (CCRF-CEM) and exposed them to 900 MHz microwave EMF from a TEM cell at short and long exposure times. They evaluated the effect of high-frequency EMF on gene expression and identified functional pathways influenced by the exposure.

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