3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 355 studies (Cell Studies)

Oxidative Stress215 citations

Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs.

Meral I et al. · 2007

Researchers exposed guinea pigs to cell phone radiation (900 MHz) for 12 hours daily over 30 days and found significant oxidative stress in brain tissue. The radiation increased harmful compounds called free radicals while depleting the brain's natural antioxidant defenses. This suggests that prolonged cell phone exposure may damage brain cells through oxidative stress, the same process linked to aging and neurodegenerative diseases.

Oxidative Stress149 citations

Effects of magnetic field on the antioxidant enzyme activities of suspension-cultured tobacco cells

Sahebjamei H, Abdolmaleki P, Ghanati F · 2007

Researchers exposed tobacco plant cells to static magnetic fields of 10 and 30 millitesla for 5 hours daily over 5 days to study effects on cellular defense systems. The magnetic field exposure disrupted the cells' antioxidant enzyme balance, decreasing some protective enzymes while increasing cellular damage markers. This suggests that magnetic fields can weaken biological cells' ability to defend against harmful oxidative stress.

Biophoton emission of MDCK cell with hydrogen peroxide and 60 Hz AC magnetic field.

Cheun BS, Yi SH, Baik KY, Lim JK, Yoo JS, Shin HW, Soh KS · 2007

Researchers exposed canine kidney cells to a 60 Hz magnetic field (the same frequency as household electricity) while measuring their light emission when stressed by hydrogen peroxide. The magnetic field altered how cells responded to oxidative stress, changing the pattern of light they emitted. This suggests that power frequency magnetic fields can influence cellular stress responses at the biochemical level.

Effects of GSM 1800 MHz on dendritic development of cultured hippocampal neurons.

Ning W, Xu SJ, Chiang H, Xu ZP, Zhou SY, Yang W, Luo JH · 2007

Researchers exposed developing rat brain cells to cell phone radiation and found that higher exposure levels (2.4 W/kg) significantly reduced the formation of dendritic spines, which are essential for brain cell communication, suggesting potential interference with normal brain development during critical growth periods.

Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs.

Meral I et al. · 2007

Researchers exposed guinea pigs to cell phone radiation for 12 hours daily over 30 days and measured brain tissue damage. They found increased oxidative stress (cellular damage from free radicals) in the brain, with higher levels of harmful compounds and lower levels of protective antioxidants. This suggests that prolonged cell phone radiation exposure may damage brain cells through oxidative stress mechanisms.

DNA & Genetic DamageNo Effects Found

The number of genes changing expression after chronic exposure to Code Division Multiple Access or Frequency DMA radiofrequency radiation does not exceed the false-positive rate.

Whitehead TD, Moros EG, Brownstein BH, Roti Roti JL. · 2006

Researchers exposed mouse cells to cell phone radiation at 5 watts per kilogram for 24 hours to see if it changed gene activity. They found no meaningful changes in gene expression - the few changes they detected were no more than would occur by random chance. This suggests cell phone radiation at this level doesn't trigger cellular responses that could lead to biological effects.

Brain & Nervous SystemNo Effects Found

Exposure of Cultured Astroglial and Microglial Brain Cells to 900 MHz Microwave Radiation.

Thorlin et al. · 2006

Swedish researchers exposed brain glial cells (support cells that protect neurons) to 900 MHz radiation at various power levels for up to 24 hours to see if it would trigger inflammatory responses or cellular damage. They found no significant effects on inflammatory markers, cellular proteins, or cell structure at any exposure level tested. The study suggests that short-term exposure to 900 MHz radiation at these levels does not cause detectable damage to these important brain cells in laboratory conditions.

Brain & Nervous SystemNo Effects Found

Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease.

Túnez I et al. · 2006

Researchers tested whether transcranial magnetic stimulation (TMS) could protect brain cells from damage caused by a toxic chemical that mimics Huntington's disease in rats. They found that TMS prevented cell death and reduced harmful oxidative stress in the brain region most affected by the disease. This suggests magnetic field therapy might offer neuroprotective benefits for degenerative brain conditions.

Evidence for a specific microwave radiation effect on the green fluorescent protein.

Copty AB, Neve-Oz Y, Barak I, Golosovsky M, Davidov D. · 2006

Researchers at Hebrew University exposed green fluorescent protein (a common laboratory marker) to 8.5 GHz microwave radiation and compared the effects to conventional heating. While both methods reduced the protein's fluorescence and shifted its color spectrum, the microwave exposure caused additional changes that couldn't be explained by heat alone. This suggests microwave radiation has specific biological effects beyond just warming tissues.

Engrossed in conversation: The impact of cell phones on simulated driving performance.

Beede KE, Kass SJ. · 2006

Researchers tested 36 college students in driving simulators to see how hands-free cell phone conversations affected their driving ability. They found that talking on the phone significantly impaired performance in all four areas measured: traffic violations (like speeding), lane maintenance, attention lapses (like stopping at green lights), and reaction times. The study demonstrates that even hands-free phone calls create dangerous cognitive distractions while driving.

Iron-radiofrequency synergism in lymphomagenesis.

Anghileri LJ, Mayayo E, Domingo JL. · 2006

Researchers investigated whether iron supplements might worsen cancer risk from radiofrequency radiation exposure using animals that naturally develop lymphomas (blood cancers) as they age. They found that combining radiofrequency exposure with iron injections created a synergistic effect, meaning the combination was more dangerous than either factor alone. This suggests that people receiving iron therapy might face increased cancer risk from RF radiation exposure.

Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons.

Xu S, Ning W, Xu Z, Zhou S, Chiang H, Luo J. · 2006

Researchers exposed rat brain cells to 1800-MHz cell phone radiation (the same frequency used by GSM phones) for 15 minutes daily over 8 days. They found that this exposure weakened the electrical connections between brain cells in the hippocampus, the brain region crucial for memory and learning. The radiation reduced the strength of signals that brain cells use to communicate with each other.

Effects of a 2450 MHz high-frequency electromagnetic field with a wide range of SARs on the induction of heat-shock proteins in A172 cells.

Wang J et al. · 2006

Researchers exposed human brain cells (A172) to microwave radiation at 2450 MHz (the same frequency used in microwave ovens and WiFi) to see if it triggers cellular stress responses. They found that extremely high radiation levels (100-200 W/kg) caused specific stress protein changes that couldn't be explained by heating alone. This suggests microwave radiation may cause biological stress in cells through mechanisms beyond just warming tissue.

Oxidative Stress104 citations

GSM Base Station Electromagnetic Radiation and Oxidative Stress in Rats.

Yurekli AI et al. · 2006

Turkish researchers exposed rats to cell tower radiation at 945 MHz for an unspecified duration and measured markers of oxidative stress (cellular damage from free radicals). They found that exposure at power levels well below current safety limits significantly increased harmful oxidative markers and decreased protective antioxidants in the rats. This suggests that even low-level electromagnetic radiation from cell towers may trigger cellular stress responses.

Magnetic fields protect from apoptosis via redox alteration

De Nicola M et al. · 2006

Researchers exposed human immune cells to magnetic fields and found that even weak fields (0.09 mT and higher) disrupted the cells' internal chemical balance, increasing harmful molecules called reactive oxygen species while decreasing protective antioxidants. Surprisingly, this cellular stress actually made the cells more resistant to programmed cell death (apoptosis), suggesting magnetic fields might interfere with normal cellular cleanup processes that eliminate damaged cells.

Cancer & TumorsNo Effects Found

Expression of the Proto-oncogene Fos after Exposure to Radiofrequency Radiation Relevant to Wireless Communications.

Whitehead TD et al. · 2005

Researchers exposed cells to radiofrequency radiation from cell phone signals (CDMA, FDMA, and TDMA) at high absorption rates of 5-10 W/kg to see if it would activate Fos, a gene linked to cellular stress and potential cancer development. They found no significant changes in Fos expression compared to unexposed cells, failing to confirm an earlier study that had reported such effects. This suggests that RF radiation at these levels may not trigger this particular cellular stress response.

Brain & Nervous SystemNo Effects Found

Effects of universal mobile telecommunications system (UMTS) electromagnetic fields on the blood-brain barrier In Vitro.

Franke H et al. · 2005

German researchers tested whether 3G cell phone signals could damage the blood-brain barrier (the protective filter that keeps toxins out of the brain) by exposing pig brain cells to UMTS signals for up to 84 hours. They found no evidence that the radiofrequency radiation affected the barrier's protective function, permeability, or structural proteins. This suggests that 3G signals at typical phone exposure levels may not compromise this critical brain protection system.

DNA & Genetic DamageNo Effects Found

Genotoxicity evaluation of electromagnetic fields generated by 835-MHz mobile phone frequency band.

Chang SK et al. · 2005

Researchers exposed bacterial cells to 835-MHz mobile phone radiation at high intensity (4 W/kg SAR) for 48 hours to test whether it causes DNA damage or genetic mutations. The study found no evidence that this radiofrequency radiation caused DNA breakdown or increased mutation rates in the bacterial test systems. This suggests that mobile phone frequencies may not directly damage genetic material under these laboratory conditions.

Role of mobile phones in motor vehicle crashes resulting in hospital attendance: a case-crossover study.

McEvoy SP et al. · 2005

Researchers studied whether cell phone use affects driving safety by examining drivers who had crashes requiring hospital treatment. They found that using a mobile phone within 10 minutes before a crash increased the likelihood of crashing by four times, regardless of whether drivers used hands-free or handheld devices. This suggests that the cognitive distraction from phone conversations, not just physical handling, creates dangerous driving conditions.

Influence of (460 MHz) electromagnetic fields on the induced lipid peroxidation in the structures of visual analyzer and hypothalamus in experimental animals

Musaev AV, Ismailova LF, Gadzhiev AM. · 2005

Researchers exposed rats to 460 MHz microwave radiation and measured oxidative stress (cellular damage from unstable molecules) in their brains and visual systems. They found that high-intensity microwaves caused harmful oxidative stress, while low-intensity microwaves actually activated protective antioxidant systems. This suggests that the biological effects of microwave radiation depend heavily on the exposure intensity.

Cellular telephones and driving performance: the effects of attentional demands on motor vehicle crash risk.

Hunton J, Rose JM. · 2005

Researchers compared how hands-free cell phone conversations affect driving performance compared to talking with a passenger in the car. They found that cell phone conversations require significantly more mental attention and interfere more with driving than in-person conversations because drivers must work harder to compensate for missing visual and social cues. The study also showed that people with specialized communication training (like pilots) performed better while using phones and driving.

Localized effects of microwave radiation on the intact eye lens in culture conditions.

Dovrat A et al. · 2005

Researchers exposed bovine eye lenses to low-power microwave radiation (1 GHz) for over 36 hours and found it significantly impacted the lens's optical function. While the lenses appeared to recover when radiation stopped, microscopic examination revealed permanent cellular damage that was completely different from heat-induced cataracts. This suggests microwave radiation can harm eye tissue through non-thermal mechanisms that may not be immediately visible.

Genetic damage in mobile phone users: some preliminary findings.

Gandhi G, Anita · 2005

Researchers tested 24 mobile phone users' blood cells for genetic damage and found significantly more DNA breaks and chromosomal abnormalities compared to non-users. The study used two different laboratory tests to measure cellular damage in white blood cells from people exposed to mobile phone radiation between 800-2000 MHz. These findings suggest that everyday mobile phone use may cause measurable genetic damage at the cellular level.

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