3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 355 studies (Cell Studies)

Weak magnetic fields alter stem cell-mediated growth.

Van Huizen AV et al. · 2019

Researchers studied how weak magnetic fields affect stem cells by examining tissue regeneration in planarians (flatworms that can regrow body parts). They found that depending on the magnetic field strength, these fields could either increase or decrease new tissue formation by altering stem cell activity and cellular stress responses. This suggests weak magnetic fields might be developed as therapeutic tools to control cell growth and healing processes.

Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients.

Cichoń N, Rzeźnicka P, Bijak M, Miller E, Miller S, Saluk J. · 2018

Researchers studied 57 stroke patients who received either standard physical therapy alone or combined with extremely low frequency electromagnetic field (ELF-EMF) therapy. Patients receiving the electromagnetic field treatment showed significantly reduced oxidative stress markers in their blood and better improvements in daily activities, mental function, and depression scores compared to those getting standard therapy alone. This suggests that ELF-EMF therapy may enhance stroke rehabilitation by reducing cellular damage and improving recovery outcomes.

Modulation of antioxidant enzyme gene expression by extremely low frequency electromagnetic field in post-stroke patients.

Cichon N et al. · 2018

Researchers studied 48 stroke patients who received either standard physical therapy alone or physical therapy plus extremely low frequency electromagnetic field (ELF-EMF) treatment. They found that patients receiving ELF-EMF therapy showed significantly increased activity in genes that produce antioxidant enzymes - the body's natural defense system against cellular damage. This suggests ELF-EMF therapy may help stroke patients recover by boosting their cells' ability to protect themselves from harmful oxidative stress.

Increase in Blood Levels of Growth Factors Involved in the Neuroplasticity Process by Using an Extremely Low Frequency Electromagnetic Field in Post-stroke Patients.

Cichoń N et al. · 2018

Polish researchers studied whether extremely low frequency electromagnetic fields could help stroke patients recover brain function during rehabilitation. They found that patients receiving EMF therapy alongside standard rehabilitation showed significantly higher levels of brain growth factors that promote healing and scored better on cognitive and functional recovery tests. This suggests EMF therapy may enhance the brain's natural ability to rewire itself after stroke damage.

Exposure to radiation from single or combined radio frequencies provokes macrophage dysfunction in the RAW 264.7 cell line.

López-Furelos A et al. · 2018

Spanish researchers exposed immune cells (macrophages) to radio frequency radiation at cell phone frequencies (900 MHz and 2450 MHz) for up to 72 hours. They found that the radiation significantly impaired the cells' ability to fight infections and triggered inflammatory responses, with combined frequencies causing more damage than single frequencies. This suggests that everyday exposure to multiple wireless signals simultaneously may compromise immune function.

Electromagnetic radiation 2450 MHz exposure causes cognition deficit with mitochondrial dysfunction and activation of intrinsic pathway of apoptosis in rats.

Gupta SK, Mesharam MK, Krishnamurthy S. · 2018

Researchers exposed rats to 2450 MHz electromagnetic radiation (the frequency used by WiFi and microwave ovens) for one hour daily over 28 days and found significant cognitive impairment. The radiation damaged brain cell powerhouses called mitochondria, triggered cell death pathways, and disrupted the brain's chemical messaging system. This suggests that chronic exposure to common wireless frequencies may harm memory and thinking abilities through multiple biological mechanisms.

Nitric oxide modulates the responses of osteoclast formation to static magnetic fields

Zhang J, Ding C, Meng X, Shang P · 2018

Researchers exposed bone cells to three different strengths of static magnetic fields to study how they affect osteoclast formation (cells that break down bone tissue). They found that very strong magnetic fields (16 Tesla) reduced osteoclast formation through increased nitric oxide production, while weaker fields (500 nT and 0.2 T) had the opposite effect. This suggests magnetic fields can influence bone health by altering cellular signaling pathways.

On the mechanism of the cell cycle control of suspension-cultured tobacco cells after exposure to static magnetic field.

Mohammadi F, Ghanati F, Sharifi M, Chashmi NA · 2018

Researchers exposed tobacco plant cells to weak static magnetic fields (0.2 millitesla) for 24 hours and found the magnetic field disrupted the cells' normal cycle of growth and division. The exposure triggered a cascade of cellular stress responses, including increased production of reactive molecules and changes in key proteins that control when cells divide. This demonstrates that even relatively weak magnetic fields can interfere with fundamental cellular processes.

Expressions of some antioxidant genes in SH-SY5Y cells treated with β-lapachone, morphine and electromagnetic field.

Mahmoudinasab H, Saadat M. · 2018

Researchers exposed human brain cells (neuroblastoma cells) to 50 Hz electromagnetic fields at 0.5 mT for different time patterns and measured changes in antioxidant gene expression. They found that EMF exposure altered the activity of genes responsible for protecting cells from damage, with different exposure patterns producing different effects. This suggests that even brief EMF exposures can disrupt the cellular machinery that defends against oxidative stress.

The Static Magnetic Field Remotely Boosts the Efficiency of Doxorubicin through Modulating ROS Behaviors

Hajipour Verdom B, Abdolmaleki P, Behmanesh M. · 2018

Researchers studied how static magnetic fields affect cancer treatment with doxorubicin (a common chemotherapy drug). They found that magnetic fields at 10 millitesla enhanced the drug's cancer-killing effects by increasing harmful molecules called reactive oxygen species (ROS) in cancer cells. This could potentially allow doctors to use lower doses of chemotherapy while maintaining effectiveness, reducing side effects for patients.

Static magnetic fields modulate the response of different oxidative stress markers in a restraint stress model animal.

Coballase-Urrutia E et al. · 2018

Researchers exposed stressed laboratory animals to weak static magnetic fields (0.8 mT) for varying durations over 5 days and measured markers of cellular damage called oxidative stress. They found that magnetic field exposure significantly reduced harmful oxidative stress markers while boosting the body's natural antioxidant defenses. The protective effects were time-dependent, suggesting that controlled magnetic field exposure might help the body cope with stress-related cellular damage.

Whole Body / GeneralNo Effects Found

The effects of microwave radiation on rabbit's retina

Talebnejad MR et al. · 2017

Researchers exposed 40 rabbits to cell phone-simulated microwave radiation at two distances (10 cm and 30 cm) for up to 3 days, then examined their retinas one week later. While they found no significant damage to the retina itself, they observed increased blood vessel congestion in the ciliary body (part of the eye that produces fluid) in rabbits exposed to higher radiation doses. The study suggests cell phone radiation may cause subtle eye changes even when major damage isn't apparent.

DNA & Genetic DamageNo Effects Found

RF-EMF exposure at 1800 MHz did not elicit DNA damage or abnormal cellular behaviors in different neurogenic cells.

Su L, Wei X, Xu Z, Chen G · 2017

Researchers exposed three types of brain cells to cell phone radiation (1800 MHz) at high power levels for up to 24 hours to see if it would damage DNA or disrupt normal cell behavior. They found no evidence of DNA breaks, changes in cell growth, or other harmful effects even at radiation levels twice as high as current safety limits. The study suggests that this frequency of radiofrequency radiation may not directly damage brain cells in laboratory conditions.

DNA & Genetic DamageNo Effects Found

No evidence of DNA damage by co-exposure to extremely low frequency magnetic fields and aluminum on neuroblastoma cell lines

Villarini M et al. · 2017

Italian researchers exposed brain cancer cells (neuroblastoma) to 50 Hz magnetic fields and aluminum compounds, both separately and together, to see if they would cause DNA damage. After exposing the cells to magnetic field levels ranging from 0.01 to 1 mT for up to 5 hours, they found no DNA damage, no changes in cellular stress markers, or any harmful synergistic effects when the exposures were combined. This suggests that short-term exposure to these power-frequency magnetic fields, even in combination with aluminum, does not appear to damage DNA in these particular brain cell types.

Mobile phone use and glioma risk: A systematic review and meta-analysis.

Yang M et al. · 2017

Researchers analyzed 11 studies involving over 17,000 people to examine whether cell phone use increases brain tumor risk. They found that using a phone for 10 or more years increased the odds of developing glioma (a type of brain tumor) by 44%, with the strongest association for tumors on the same side of the head where people held their phone. The risk was particularly high for low-grade gliomas, which more than doubled with long-term use.

Radiofrequency radiations induced genotoxic and carcinogenic effects on chickpea (Cicer arietinum L.) root tip cells.

Qureshi ST, Memon SA, Abassi AR, Sial MA, Bughio FA. · 2017

Pakistani researchers exposed chickpea seeds to radiation from cell phones (900 MHz) and laptops (3.31 GHz) for 24 and 48 hours to study DNA damage. They found that both devices caused genetic damage to plant cells, with laptop radiation being more harmful than cell phone radiation. The study suggests these everyday devices could potentially cause DNA damage and cancer-like changes in living tissue.

Adaptive Response Induced by Pre-Exposure to 915 MHz Radiofrequency: A Possible Role for Antioxidant Enzyme Activity.

Mortazavi SMJ et al. · 2017

Iranian researchers exposed rats to 915 MHz radiofrequency radiation (similar to microwave ovens) for 4 hours daily over one week, then tested whether this 'primed' their liver cells to better handle a subsequent dose of gamma radiation. They found that low-power RF exposure increased antioxidant enzymes like glutathione, which helped protect liver tissue from oxidative damage when the rats were later exposed to harmful gamma radiation.

Acute effects of 30 minutes of exposure to a smartphone call on in vitro platelet function.

Lippi G et al. · 2017

Italian researchers exposed blood samples from 16 healthy volunteers to smartphone radiation (900 MHz) for 30 minutes and found significant changes in platelet function. The exposed blood showed altered clotting behavior and increased platelet size compared to unexposed samples. This suggests that smartphone radiation can directly affect blood components involved in clotting and wound healing.

Effect of Radiofrequency Radiation Emitted from 2G and 3G Cell Phone on Developing Liver of Chick Embryo - A Comparative Study.

D'Silva MH, Swer RT, Anbalagan J, Rajesh B. · 2017

Researchers exposed developing chick embryos to radiation from 2G and 3G cell phones throughout their development and examined the effects on liver tissue. They found significant structural damage to liver cells, including bleeding, cellular swelling, and DNA breaks, with 3G radiation causing more severe damage than 2G. This suggests that developing tissues may be particularly vulnerable to cell phone radiation during critical growth periods.

Exposure to 2100 MHz electromagnetic field radiations induces reactive oxygen species generation in Allium cepa roots.

Chandel S, Kaur S, Singh HP, Batish DR, Kohli RK. · 2017

Researchers exposed onion roots to 2100 MHz cell phone radiation for 1-4 hours and measured cellular damage markers. The exposure triggered increased production of harmful reactive oxygen species (unstable molecules that damage cells) and forced the plants to ramp up their antioxidant defenses. This demonstrates that cell phone frequencies can disrupt normal cellular processes even in plant tissue.

Evaluation of Mobile Phone and Cordless Phone Use and Glioma Risk Using the Bradford Hill Viewpoints from 1965 on Association or Causation.

Carlberg M, Hardell L. · 2017

Researchers used a rigorous scientific framework to evaluate whether mobile and cordless phone use causes brain tumors called gliomas. They found that people with the highest phone use had a 90% increased risk of developing gliomas, with risk doubling for those using wireless phones for 20+ years. The study concluded that radiofrequency radiation from phones should be classified as a human carcinogen.

Exposure to a specific time-varying electromagnetic field inhibits cell proliferation via cAMP and ERK signaling in cancer cells.

Buckner CA, Buckner AL, Koren SA, Persinger MA, Lafrenie RM. · 2017

Researchers exposed multiple types of cancer cells to a specific low-frequency electromagnetic field pattern (25-6 Hz) for one hour daily and found it significantly slowed cancer cell growth without affecting healthy cells. The EMF exposure worked by altering specific cellular signaling pathways (cAMP and ERK) that control cell division. This suggests certain EMF patterns might have therapeutic potential for cancer treatment by selectively targeting malignant cells.

The expression of pluripotency and neuronal differentiation markers under the influence of electromagnetic field and nitric oxide.

Haghighat N, Abdolmaleki P, Parnian J, Behmanesh M. · 2017

Researchers exposed stem cells from rat bone marrow to 50 Hz electromagnetic fields (the same frequency as power lines) combined with nitric oxide, a natural cellular messenger. They found that EMF exposure combined with high levels of nitric oxide forced stem cells to transform into nerve cells, while low nitric oxide levels helped protect the cells' original stem cell properties. This suggests that EMF exposure can influence how our cells develop and differentiate, potentially affecting tissue repair and regeneration.

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