Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.
Showing 1,014 studies (Rodent Studies)
Li H et al. · 2014
Researchers exposed rats to WiFi-like microwave radiation (2.856 GHz) for six weeks and found dose-dependent learning and memory problems, plus brain damage in the hippocampus. The study shows that chronic low-level microwave exposure can impair brain function through disrupted brain chemistry.
Júnior LC et al. · 2014
Brazilian researchers exposed rats to cell phone radiation (1.8 GHz) for three days using simulated phone calls and then tested their behavior and memory. While the rats showed no memory problems or anxiety, they did exhibit stress-related behaviors when exposed to the radiation. This suggests that even short-term cell phone radiation exposure may trigger stress responses in the brain, even when other cognitive functions appear normal.
Hu S et al. · 2014
Researchers exposed rats to high-power microwave radiation for 15 minutes and found it caused memory problems and brain damage. However, when rats were given a dietary supplement called Kang-fu-ling for two weeks, it protected their brains from this microwave-induced damage by reducing harmful oxidative stress (cellular damage from free radicals). This suggests certain antioxidant compounds might help protect the brain from microwave radiation effects.
Ghazizadeh V, Nazıroğlu M · 2014
Researchers exposed brain and nerve cells from epileptic rats to Wi-Fi radiation (2.45 GHz) for one hour and found it triggered additional calcium influx and cell death beyond what epilepsy alone caused. The Wi-Fi exposure activated specific calcium channels (TRPV1) that allowed harmful calcium to flood into neurons, leading to oxidative stress and programmed cell death. This suggests Wi-Fi radiation may worsen neurological conditions by overwhelming brain cells with calcium.
Akbari A, Jelodar G, Nazifi S · 2014
Researchers exposed rats to radiofrequency waves from a cell tower antenna model for 4 hours daily over 45 days and found it caused oxidative stress in brain tissue. The radiation damaged the brain's natural antioxidant defenses and increased harmful compounds called free radicals. However, when rats were given vitamin C supplements, this damage was significantly reduced, suggesting antioxidants may help protect against RF radiation effects.
Yang L, Hao D, Wu S, Zhong R, Zeng Y. · 2013
Researchers used computer modeling to calculate how much radiofrequency energy would be absorbed by rat brains during a 900 MHz cell phone frequency exposure experiment. They found that the exposure levels used in their memory study would not cause any significant temperature rise in the brain tissue. This dosimetry study provided the technical foundation for understanding whether any biological effects found in their related memory research could be attributed to heating or non-thermal mechanisms.
Tumkaya L, Kalkan Y, Bas O, Yilmaz A. · 2013
Turkish researchers exposed young male rats to mobile phone radiation for one hour daily during their pubertal development (45 days total) and found no damage to testicular tissue structure or sperm-producing cells. The study examined tissue samples under microscopes using multiple staining techniques to detect any cellular abnormalities or signs of cell death. This suggests that mobile phone radiation at low absorption rates may not harm male reproductive development during puberty.
Trošić I, Mataušić-Pišl M, Pavičić I, Marjanović AM. · 2013
Researchers exposed male rats to 915 MHz radiofrequency radiation (similar to cell phone frequencies) for one hour daily over two weeks to study effects on reproductive health. They found no significant changes in testicular structure, sperm count, sperm mobility, or sperm appearance compared to unexposed rats. The study suggests that short-term intermittent RF exposure at these levels may not pose immediate risks to male reproductive function.
Poulletier de Gannes F et al. · 2013
French researchers exposed rats to Wi-Fi signals (2.45 GHz) for one hour daily during sexual maturation, mating, and pregnancy to test effects on fertility and fetal development. The study found no harmful effects on reproductive organs, fertility rates, or fetal abnormalities, even at high exposure levels of 4 watts per kilogram. This suggests Wi-Fi exposure at these levels may not significantly impact reproductive health in rats.
Kim HS et al. · 2013
Researchers exposed rats to 915 MHz RFID radiation for up to 16 weeks at high intensity levels (4 W/kg SAR) and measured brain glucose metabolism using advanced PET scanning. They found no changes in how the brain processed glucose in any region examined, suggesting this type of radiofrequency exposure didn't alter basic brain energy function. This matters because brain glucose metabolism is a fundamental indicator of neural activity and health.
Gurbuz N, Sirav B, Colbay M, Yetkin I, Seyhan N. · 2013
Turkish researchers exposed rats to cell phone frequencies (1800 and 2100 MHz) for 30 minutes daily over one to two months, then examined their bladder cells for micronuclei-tiny fragments that indicate DNA damage. The study found no significant increase in these genetic damage markers compared to unexposed control rats, suggesting the RF radiation did not cause detectable DNA damage in bladder tissue at the tested exposure levels.
Furtado-Filho OV et al. · 2013
Brazilian researchers exposed young rats to 950 MHz radiofrequency radiation (similar to older cell phone frequencies) for 30 minutes daily from birth through 30 days of age. While the study found no oxidative stress or DNA damage in most age groups, 30-day-old rats showed genetic damage in liver cells, and newborns had altered fatty acid levels and reduced antioxidant enzyme production.
Aït-Aïssa S et al. · 2013
French researchers exposed pregnant rats and their offspring to WiFi signals (2.4 GHz) from pregnancy through 5 weeks after birth, then examined their brains for signs of cellular stress and damage. They found no differences in stress markers between WiFi-exposed and unexposed rat pups, even at exposure levels up to 4 W/kg. The study suggests that WiFi exposure during critical developmental periods may not cause detectable brain damage in young rats.
Ahlers MT, Ammermüller J. · 2013
German researchers exposed isolated mouse retina cells to mobile phone radiation (GSM-900, GSM-1800, and UMTS) at various power levels while carefully controlling temperature. They found no changes in how these vision-critical cells responded to light stimuli, even at radiation levels 10 times higher than typical phone use. This suggests mobile phone radiation doesn't directly interfere with retinal function under controlled laboratory conditions.
Zhang C, Li Y, Wang C, Lv R, Song T. · 2013
Researchers exposed rats to 50 Hz magnetic fields (the type from power lines) for 12 weeks to see if this exposure would worsen Alzheimer's-like symptoms caused by aluminum poisoning. They found that magnetic field exposure alone had no effect on brain function or Alzheimer's markers, and it didn't make aluminum-induced brain damage any worse. This suggests that power-frequency magnetic fields may not contribute to Alzheimer's disease development.
Akdag MZ et al. · 2013
Researchers exposed rats to 50 Hz magnetic fields (the same frequency as power lines) for 10 months to test effects on sperm health, cell death, and oxidative stress. They found no impact on sperm count or quality, and no oxidative damage at either exposure level tested. However, higher exposure (500 μT) did increase markers of programmed cell death in testicular tissue.
Zhang C, Li Y, Wang C, Lv R, Song T · 2013
Researchers exposed rats to extremely low frequency magnetic fields (50 Hz at 100 µT) for 12 weeks to test whether EMF exposure could worsen Alzheimer's disease symptoms caused by aluminum poisoning. The magnetic field exposure alone showed no effect on brain health, and it didn't make aluminum-induced brain damage any worse. This suggests that EMF exposure at these levels doesn't contribute to Alzheimer's disease development.
Kim HS et al. · 2013
Researchers exposed rats to 915 MHz radiofrequency radiation (used in RFID systems) for up to 16 weeks and measured brain glucose metabolism using advanced PET scanning. They found no changes in how the brain used glucose in any region tested, even at high exposure levels of 4 W/kg SAR. This suggests RFID radiation at these levels doesn't alter basic brain energy function in the short to medium term.
Aït-Aïssa S et al. · 2013
French researchers exposed pregnant rats and their newborns to WiFi signals (2450 MHz) for 2 hours daily during pregnancy and early life, then examined brain tissue for signs of stress and damage. They found no differences in stress markers or heat-shock proteins between exposed and unexposed rats at any of the tested exposure levels. The study suggests that WiFi exposure during critical developmental periods may not cause detectable brain damage in rats.
Ahlers MT, Ammermüller J · 2013
German researchers exposed isolated mouse retinal tissue to cell phone radiation at various power levels (including some 10 times higher than typical phone use) to see if it affected eye cells that help process vision. They found no changes in how these retinal ganglion cells responded to light, even at the highest radiation levels tested. The study was carefully controlled to eliminate temperature effects, focusing only on potential non-thermal impacts of RF radiation on eye function.
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
Researchers exposed newborn rat brain cells to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwaves) for just 10 minutes and found significant neuronal damage. The brain cells showed decreased viability, increased cell death, and abnormal protein changes associated with neurodegenerative diseases like Alzheimer's. The study identified a specific cellular pathway (p25/CDK5) that appears to drive this RF-induced brain cell injury.
Orhan Baş et al. · 2013
Researchers exposed pregnant rats to 900 MHz radiofrequency radiation (similar to cell phone frequencies) during a critical brain development period and found significant loss of brain cells in the hippocampus region of their female offspring. The exposed rat pups had fewer pyramidal cells in the cornu ammonis, a brain area crucial for memory and learning. This suggests that EMF exposure during pregnancy may harm developing brains, potentially affecting cognitive function later in life.
Meo SA, Al Rubeaan K · 2013
Researchers exposed rats to cell phone radiation for different durations daily over three months and measured their blood sugar levels. Rats exposed for more than 15 minutes per day developed significantly higher fasting blood glucose and insulin levels, along with increased insulin resistance (when cells don't respond properly to insulin). This suggests that regular cell phone radiation exposure may disrupt normal blood sugar regulation, potentially contributing to diabetes risk.
Lin WT, Chang CH, Cheng CY, Chen MC, Wen YR, Lin CT, Lin CW. · 2013
Researchers tested how different types of pulsed radiofrequency (RF) signals affect pain relief in rats with nerve damage. They found that sinusoidal (smooth wave) RF signals provided better pain relief than square wave signals when applied to nerve clusters at the spine. The study also measured inflammatory markers in spinal tissue to understand how RF treatment reduces pain responses.
Koca O et al. · 2013
Turkish researchers exposed rats to cell phone radiation for 8 hours daily over 20 days using a Philips phone with high radiation output. They found significant kidney damage including damaged filtering units (glomeruli), swollen tissue spaces, and inflammation in exposed rats compared to unexposed controls. The damage persisted even 20 days after exposure ended, suggesting lasting effects from intensive cell phone use.