3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

2.1 GHz electromagnetic field does not change contractility and intracellular Ca2+ transients but decreases β-adrenergic responsiveness through nitric oxide signaling in rat ventricular myocytes.

Olgar Y et al. · 2015

Researchers exposed rats to 2.1 GHz radiofrequency radiation (similar to cell phone frequencies) for 2 hours daily over 10 weeks and studied heart muscle cells. While basic heart function remained normal, the cells showed reduced responsiveness to stress hormones like adrenaline, and nitric oxide levels increased in heart tissue. This suggests that chronic EMF exposure may impair the heart's ability to respond properly during physical or emotional stress.

Exposure to a 900 MHz electromagnetic field for one hour a day over 30 days does change the histopathology and biochemistry of the rat testis.

Odacı E, Özyılmaz C · 2015

Turkish researchers exposed male rats to cell phone-frequency radiation (900 MHz) for one hour daily over 30 days and examined the effects on testicular tissue. They found significant structural damage including tissue swelling, reduced sperm-producing tube size, increased cell death, and disrupted antioxidant systems. The findings suggest that even moderate daily exposure to cell phone radiation may harm male reproductive organs.

Epilepsy but not mobile phone frequency (900 MHz) induces apoptosis and calcium entry in hippocampus of epileptic rat: involvement of TRPV1 channels.

Nazıroğlu M, Özkan FF, Hapil SR, Ghazizadeh V, Çiğ B · 2015

Turkish researchers exposed brain cells from epileptic rats to 900 MHz mobile phone radiation for one hour to see if it would worsen brain damage. They found that epilepsy itself caused significant cell death and oxidative stress in the hippocampus (the brain's memory center), but adding mobile phone radiation didn't make these effects any worse. This suggests that in already-damaged brain tissue, short-term mobile phone exposure may not add additional harm beyond what the underlying condition already causes.

EFFECTS OF CHRONIC EXPOSURE TO 2G AND 3G CELL PHONE RADIATION ON MICE TESTIS – A RANDOMIZED CONTROLLED TRIAL

Mugunthan N et al. · 2015

Researchers exposed mice to cell phone radiation from 2G and 3G phones for 48 minutes daily over six months and examined the effects on reproductive organs. The study found significant damage to testicular tissue, including reduced testosterone levels, fewer sperm-producing cells, and structural damage to the tubes where sperm develop. Both 2G and 3G radiation produced similar harmful effects on male fertility.

Exposure to non-ionizing radiation provokes changes in rat thyroid morphology and expression of HSP-90

Misa-Agustiño MJ et al. · 2015

Spanish researchers exposed rats to 2.45 GHz radiation (the same frequency as Wi-Fi and microwave ovens) and found significant changes in thyroid gland structure. The radiation caused thyroid follicles to swell and shrink in different patterns depending on exposure duration and power levels. These structural changes suggest the thyroid gland was responding to radiation stress, raising questions about potential long-term effects on thyroid function in humans exposed to similar frequencies.

EMF radiation at 2450MHz triggers changes in the morphology and expression of heat shock proteins and glucocorticoid receptors in rat thymus.

Misa-Agustiño MJ et al. · 2015

Researchers exposed rats to 2.45 GHz radiofrequency radiation (the same frequency used in microwave ovens and WiFi) and found it caused visible damage to the thymus, a key immune system organ. The radiation triggered cellular stress responses, increased blood vessel leakage, and altered stress proteins even at levels below those that cause heating. This suggests that EMF exposure can disrupt immune system function through non-thermal biological mechanisms.

Enhancement of Cortical Network Activity in vitro and Promotion of GABAergic Neurogenesis by Stimulation with an Electromagnetic Field with a 150 MHz Carrier Wave Pulsed with an Alternating 10 and 16 Hz Modulation.

Gramowski-Voß A et al. · 2015

German researchers exposed developing mouse brain tissue to electromagnetic fields combining low frequencies (10 and 16 Hz) with a higher carrier frequency (150 MHz) for 10 days. The exposure accelerated brain development, increased electrical activity, and promoted the growth of specific neurons called GABAergic neurons, which help regulate brain function. The researchers suggest this type of electromagnetic stimulation might have therapeutic potential for treating neurodegenerative diseases like Alzheimer's.

Influence of electromagnetic field (1800 MHz) on lipid peroxidation in brain, blood, liver and kidney in rats.

Bodera P et al. · 2015

Researchers exposed rats to 1800 MHz radiofrequency radiation (similar to cell phone signals) five times for 15 minutes each and measured oxidative damage in their organs. The EMF exposure increased lipid peroxidation (a marker of cellular damage from free radicals) in the brain, blood, and kidneys, particularly when combined with a pain medication. This suggests that even brief, repeated exposure to cell phone-level radiation may cause measurable oxidative stress in vital organs.

The radioprotective effects of Moringa oleifera against mobile phone electromagnetic radiation-induced infertility in rats.

Bin-Meferij MM, El-Kott AF. · 2015

Researchers exposed male rats to cell phone radiation (900 MHz) for one hour daily over several weeks and found significant damage to sperm quality, count, and testicular tissue structure. The radiation caused irregular sperm development, cell death, and reduced fertility markers. However, when rats were also given Moringa leaf extract (a plant rich in antioxidants), the protective compounds largely prevented this reproductive damage.

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development.

Bedir R et al. · 2015

Turkish researchers exposed pregnant rats to 900 MHz electromagnetic fields (the same frequency used by many cell phones) during the first 20 days of pregnancy and examined the kidney development of their offspring. They found that prenatal EMF exposure caused structural abnormalities in the developing kidneys, including tissue congestion, tubular defects, and increased cell death. This suggests that EMF exposure during pregnancy may interfere with normal organ development in the fetus.

The effects of 2100-MHz radiofrequency radiation on nasal mucosa and mucociliary clearance in rats.

Aydoğan F et al. · 2015

Researchers exposed rats to 2100 MHz radiofrequency radiation (simulating 3G cell phone signals) for 6 hours daily over 10 or 40 days to study effects on nasal tissue and mucus clearance. The exposed rats showed significant damage to nasal tissue, including cell death, loss of protective cilia (tiny hair-like structures), and impaired ability to clear mucus from nasal passages. This matters because our nasal passages are a primary defense against airborne pathogens, and cell phone radiation may be compromising this natural protective mechanism.

Common behaviors alterations after extremely low-frequency electromagnetic field exposure in rat animal model.

Mahdavi SM, Sahraei H, Rezaei-Tavirani M, Najafi Abedi A. · 2015

Iranian researchers exposed rats to 40 Hz electromagnetic fields (the same frequency used in many electrical systems) for 21 days and tracked changes in behavior and metabolism. They found significant disruptions including altered body weight patterns, reduced appetite, elevated blood glucose levels, and decreased movement and exploration behaviors. These findings suggest that even relatively low-frequency electromagnetic fields can disrupt normal biological functions in mammals.

Effects of prenatal 900 MHz electromagnetic field exposures on the histology of rat kidney.

Ulubay M et al. · 2015

Researchers exposed pregnant rats to 900 MHz electromagnetic fields (the frequency used by older cell phones) and examined their offspring's kidneys at four weeks old. They found that prenatal EMF exposure caused the kidneys to grow abnormally larger while reducing the number of glomeruli (tiny filtering units essential for kidney function). Importantly, supplementing with melatonin or omega-3 fatty acids during pregnancy prevented these harmful effects.

The effects of prenatal long-duration exposure to 900-MHz electromagnetic field on the 21-day-old newborn male rat liver.

Topal Z et al. · 2015

Researchers exposed pregnant rats to cell phone radiation (900 MHz) for one hour daily during the final third of pregnancy, then examined their male offspring at three weeks old. The exposed pups showed significant liver damage, including cellular death and increased oxidative stress markers. This suggests that prenatal exposure to wireless radiation may cause lasting organ damage that persists after birth.

Exposure to mobile phone electromagnetic field radiation, ringtone and vibration affects anxiety-like behaviour and oxidative stress biomarkers in albino wistar rats.

Shehu A, Mohammed A, Magaji RA, Muhammad MS. · 2015

Researchers exposed rats to mobile phone radiation, ringtones, and vibrations for 10 minutes daily over 4 weeks to study effects on anxiety and brain chemistry. All exposed groups showed increased anxiety-like behavior, while rats exposed to ringtones or combined ringtone/vibration also had reduced levels of catalase, an important antioxidant enzyme in the brain. This suggests that mobile phone emissions may affect both behavior and the brain's ability to protect itself from cellular damage.

Impact of 2.45 GHz microwave radiation on the testicular inflammatory pathway biomarkers in young rats: The role of gallic acid.

Saygin M, Asci H, Ozmen O, Cankara FN, Dincoglu D, Ilhan I. · 2015

Researchers exposed young male rats to 2.45 GHz microwave radiation (the same frequency used by WiFi and microwaves) for 3 hours daily over 30 days and found significant damage to their testes. The radiation increased oxidative stress, triggered inflammation, and reduced sperm production in the animals' reproductive organs. However, when rats received gallic acid (a natural antioxidant) alongside the radiation exposure, it protected against much of this testicular damage.

2.1 GHz electromagnetic field does not change contractility and intracellular Ca2+ transients but decreases β-adrenergic responsiveness through nitric oxide signaling in rat ventricular myocytes.

Olgar Y et al. · 2015

Researchers exposed rats to 2.1 GHz radiofrequency radiation (similar to cell phone frequencies) for 2 hours daily over 10 weeks and studied how their heart muscle cells responded. While the basic heart muscle contractions remained normal, the cells became less responsive to adrenaline-like stress hormones, and nitric oxide levels in the heart increased significantly. This suggests that chronic RF exposure may alter how the heart responds to stress, even when basic heart function appears unchanged.

Exposure to a 900 MHz electromagnetic field for one hour a day over 30 days does change the histopathology and biochemistry of the rat testis.

Odacı E, Özyılmaz C. · 2015

Researchers exposed male rats to 900 MHz electromagnetic fields (the same frequency used by cell phones) for one hour daily over 30 days and found significant damage to testicular tissue and function. The EMF-exposed rats showed structural damage to sperm-producing tubes, increased cell death, and reduced levels of important antioxidants that protect against cellular damage. This suggests that chronic exposure to cell phone-level radiation may harm male reproductive health.

Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900-MHz electromagnetic field during early and mid-adolescence.

İkinci A et al. · 2015

Researchers exposed young male rats to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for one hour daily during adolescence and examined their spinal cords. They found significant damage including breakdown of the protective myelin sheaths around nerve fibers, increased oxidative stress markers, and structural abnormalities in nerve cells. This suggests that radiofrequency exposure during critical developmental periods may harm the developing nervous system.

Can prenatal exposure to a 900 MHz electromagnetic field affect the morphology of the spleen and thymus, and alter biomarkers of oxidative damage in 21-day-old male rats?

Hancı H et al. · 2015

Researchers exposed pregnant rats to 900 MHz cell phone radiation for one hour daily and examined the immune organs (spleen and thymus) of their male offspring at 21 days old. The prenatal radiation exposure caused significant oxidative damage and structural abnormalities in these critical immune system organs. This suggests that EMF exposure during pregnancy may compromise immune system development in offspring.

Microwave Exposure Impairs Synaptic Plasticity in the Rat Hippocampus and PC12 Cells through Over-activation of the NMDA Receptor Signaling Pathway.

Xiong L et al. · 2015

Researchers exposed rats and nerve cells to microwave radiation at levels similar to wireless devices. The exposure damaged brain synapses (nerve cell connections) and disrupted brain chemicals essential for memory formation, suggesting microwave radiation may impair learning and memory abilities.

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