Klaeboe L, Blaasaas KG, Tynes T. · 2007
Researchers tested whether radio-frequency electromagnetic fields from mobile phones increase the incidence of gliomas, meningiomas, and acoustic neuromas in adults. They collected detailed mobile phone use information from 289 glioma patients, 207 meningioma patients, 45 acoustic neuroma patients, and 358 controls. For regular mobile phone use defined as at least once a week for at least six months, the odds ratios were 0.6 for gliomas, 0.8 for meningiomas, and 0.5 for acoustic neuromas. No increasing trend was observed for gliomas or acoustic neuromas with longer duration, time since first use, or cumulative use. The results indicate that mobile phone use is not associated with an increased risk of these tumors.
Kan P, Simonsen SE, Lyon JL, Kestle JR. · 2007
Researchers conducted a meta-analysis of nine case-control studies with 5,259 brain tumor cases and 12,074 controls to examine cellular phone use and brain tumor risk. The pooled analysis showed an overall odds ratio of 0.90 with a 95% confidence interval of 0.81 to 0.99 for cellular phone use and brain tumor development. For long-term users of ten years or more, the pooled odds ratio was 1.25 with a 95% confidence interval of 1.01 to 1.54 based on five studies. No increased risk was observed for analog or digital cellular phone users.
Juutilainen J, Heikkinen P, Soikkeli H, Mäki-Paakkanen J. · 2007
Jia F, Ushiyama A, Masuda H, Lawlor GF, Ohkubo C. · 2007
Researchers measured local temperature changes in rabbit pinnae during 20-minute RF exposures at SAR levels of 0, 2.3, 10.0, and 34.3 W/kg under normal blood flow and without blood flow. Blood flow significantly suppressed temperature increases even at 34.3 W/kg, while 2.3 and 10.0 W/kg did not induce significant temperature rises under normal blood flow conditions. However, 2.3 W/kg induced local skin temperature elevation when blood flow was absent. The authors concluded that physiological blood flow effects should be considered when extrapolating modeling data to living animals.
Hardell L et al. · 2007
A case-control study investigated the risk of testicular cancer in relation to use of cellular and cordless telephones. The analysis included 542 seminoma cases, 346 non-seminoma cases, and 870 controls. For seminoma, odds ratios were 1.2 for analog phones, 1.3 for digital phones, and 1.1 for cordless phones. For non-seminoma, odds ratios were 0.7 for analog phones, 0.9 for digital phones, and 1.0 for cordless phones. There was no dose-response effect and odds ratios did not increase with latency time.
Eltiti S et al. · 2007
Fifty-six self-reported sensitive and 120 control participants were tested in an open provocation test, of which 12 sensitive and 6 controls withdrew after the first session, and the remainder completed a series of double-blind tests. During the open provocation, sensitive individuals reported lower levels of well-being in both GSM and UMTS compared with sham exposure, whereas controls reported more symptoms during the UMTS exposure. During double-blind tests the GSM signal did not have any effect on either group. Sensitive participants reported elevated levels of arousal during the UMTS condition, whereas the number or severity of symptoms experienced did not increase. Physiological measures did not differ across the three exposure conditions for either group.
Davidson HC, Lutman ME. · 2007
Researchers distributed questionnaires to University of Southampton postgraduates and analyzed 117 out of 160 returned surveys. Ninety-four percent of respondents were current mobile phone users, and only two percent had never used a mobile phone. High or long-term users reported no worse hearing, tinnitus, or balance than low or short-term users.
Chauhan V et al. · 2007
Researchers exposed human-derived cell lines TK6, HL60, and Mono-Mac-6 to intermittent 1.9 GHz pulse-modulated RF fields for 6 hours at SARs of 0, 1, and 10 W/kg. Cell viability, apoptosis, and cell cycle kinetics were measured immediately after exposure and 18 hours later. Cytokine expression (TNFA, IL1B, IL6, IL8, IL10, IL12) was also assessed. No detectable changes in cell viability, cell cycle kinetics, apoptosis, or cytokine expression were observed in any exposed group compared to sham controls. The positive heat-shock control showed decreased viability, increased apoptosis, and a G(2)/M cell cycle block.
Chauhan V et al. · 2007
Researchers examined the effect of RF field exposure on late onset gene expression in U87MG cells after a 24 h exposure period. A human monocyte-derived cell line (MM6) was exposed to intermittent RF fields for 6 h and gene expression was assessed immediately and at 18 h postexposure. Both cell lines were exposed to 1.9 GHz pulse-modulated RF fields for 6 or 24 h at SARs of 0.1-10.0 W/kg. The study found no evidence that nonthermal RF field exposure altered gene expression in either U87MG or MM6 cells relative to nonirradiated controls. Heat shock at 43°C for 1 h altered the expression of well-characterized heat-shock proteins in both cell lines.
Speit G, Schütz P, Hoffmann H. · 2007
Researchers exposed ES1 cells to 1800 MHz RF-EMF at 2 W/kg SAR with intermittent exposure and tested for DNA damage using the alkaline comet assay and micronucleus test. They also tested V79 Chinese hamster cells and found no genotoxic effect in either assay. Quality control measures were used to rule out test performance issues, exposure failure, or evaluation bias.
Glover PM, Eldeghaidy S, Mistry TR, Gowland PA. · 2007
Researchers used an MRI gradient coil to produce a time-varying magnetic field of 0.5 kHz and peak field of approximately 8.7 T/s in the human brain. Visual evoked potentials were recorded from occipital sites O1 and O2 in response to a checkerboard stimulus before, during, and after a 10-minute exposure period in seven subjects. No significant effects were found on the peak amplitude or latency of the VEP P100 responses at O1 and O2.
Canseven AG, Keskil ZA, Keskil S, Seyhan N. · 2007
Researchers tested whether a 50 Hz, 0.2 mT magnetic field given before or after drug administration affected seizures induced by pentylenetetrazol in mice. The magnetic field was generated by a pair of Helmholtz coils and seizures were induced by intraperitoneal injection of pentylenetetrazol at 60 mg/kg. Forty-eight adult female mice were used and latency to seizure, total seizure duration, and mortality were recorded. Neither pre- nor post-drug magnetic field exposure had any effect on seizures or mortality rates.
Terao Y et al. · 2007
Researchers used a double-blind, counterbalanced crossover design with 10 normal subjects to test saccade performance before and after 30 minutes of mobile phone EMF exposure or sham exposure. They also measured hand reaction time to a visual signal. Saccade task parameters were unchanged after real or sham exposure, except for VGS and MGS latencies which also did not differ between exposure conditions. Hand reaction time shortened with repeated trials similarly for both exposures. The authors concluded that 30 minutes of mobile phone exposure has no significant short-term effect on saccade performance.
Stefanics G et al. · 2007
Each participant underwent a 10-minute exposure to 900 MHz pulsed EMF from a commercial Nokia 6310 mobile phone. Fifteen participants received genuine EMF exposure and fifteen received sham exposure in a double-blind, counterbalanced order. No significant differences were found in the latency of ABR waves I, III, and V before and after either genuine or sham exposure. The authors suggest that, in their experimental conditions, a single 10-minute exposure to 900 MHz EMF from a commercial mobile phone does not produce measurable immediate effects on the latency of auditory brainstem waves I, III and V.
Platano D et al. · 2007
Researchers studied the non-thermal effects of radiofrequency electromagnetic fields on barium currents through voltage-gated calcium channels in primary cultures of rat cortical neurons using the patch-clamp technique. Neurons were exposed for one to three periods of 90 seconds to 900 MHz continuous wave or GSM-modulated signals during whole-cell recording at specific absorption rates of 2 W/kg for both modulation types. Single or multiple acute exposures to either continuous wave or GSM-modulated 900 MHz fields did not significantly alter the current amplitude or the current-voltage relationship through voltage-gated calcium channels.
Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I · 2007
Researchers used a fully counterbalanced cross-over design with 12 participants to test mobile phone-like RF exposure effects on EEG. Exposures lasted 15 minutes using a dipole antenna more closely resembling a real GSM handset.
Joubert V, Leveque P, Cueille M, Bourthoumieu S, Yardin C. · 2007
Researchers exposed primary cultured neurons from embryonic Wistar rat cortices to a 900-MHz GSM field for 24 hours at 0.25 W/kg SAR. Apoptosis was measured immediately and 24 hours after exposure using DAPI staining, TUNEL/PI flow cytometry, and caspase-3 fluorimetry. No statistically significant difference in apoptosis rate was found between exposed and control neurons at either time point. All three assessment methods gave concordant results.
Irlenbusch L et al. · 2007
Researchers measured the visual discrimination threshold in 33 subjects during both RF and sham exposures. Each experiment consisted of two 30-minute periods with a 5-minute break, and the threshold was recorded every 10 seconds. The RF exposure used a 902.4 MHz GSM signal pulsed at 217 Hz with a power flux density of 1 W/m². No statistically significant difference in the threshold was found between RF and sham exposures.
Inomata-Terada S et al. · 2007
They also assessed short-interval intracortical inhibition reflecting GABAergic interneuron function using paired-pulse TMS. No effects of exposure were found on MEPs or SICI in healthy volunteers, and no effects on MEPs were observed in two multiple sclerosis patients despite conduction block after a hot bath.
Hirose H et al. · 2007
Researchers performed an in vitro study of low-level RF fields from IMT-2000 base stations to test if modulated signals cause hsp27 phosphorylation and overexpression. No significant differences in phosphorylated hsp27 at serine 82 or in hsp gene expression were found between exposed and sham-exposed groups.
Haarala C et al. · 2007
Researchers studied the effects of continuous wave and pulsed wave electromagnetic fields on cognitive function in 36 healthy male subjects. Subjects performed cognitive tasks during exposure to continuous wave, pulsed wave, and sham fields, with left- and right-sided exposure in a double-blind design. No effects were found between EMF conditions, hemisphere exposures, or between the control and experimental groups.
Fritzer G et al. · 2007
Cinel C, Boldini A, Russo R, Fox E · 2007
Yan JG, Agresti M, Bruce T, Yan YH, Granlund A, Matloub HS. · 2007
Rats exposed to 6 hours of daily cellular phone emissions for 18 weeks exhibited a significantly higher incidence of sperm cell death than control group rats through chi-squared analysis. Abnormal clumping of sperm cells was present in exposed rats and absent in controls.
Wilén J, Wiklund U, Hörnsten R, Sandström M. · 2007
The study aimed to investigate changes in heart rate variability among RF plastic sealer operators. Researchers found significantly increased total HRV and VLF power during nighttime in RF operators compared to a control group. This finding, together with a previous finding of lower nighttime heart rate, indicates a relative increase in parasympathetic cardiac modulation in RF operators.
