6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Effects of continuous prenatal and postnatal global system for mobile communications electromagnetic waves (GSM-EMW) exposure on the oxidative stress biomarkers in female rat liver

Unknown authors · 2022

Researchers continuously exposed pregnant Sprague-Dawley rats and their offspring to 900 MHz GSM-modulated RF-EMR for 24 hours per day and assessed liver oxidative stress at postnatal days 1, 9, and 21. Exposure significantly raised MDA levels at PND9 and PND21, lowered catalase activity at all ages, reduced catalase amount and mRNA at PND1 and PND9, and decreased GPx activity at PND21. CytoSOD levels increased at PND9 and 21 while mitoSOD levels decreased at PND21, and both GPx level and mitoSOD activity were elevated at all ages. SOD1 mRNA expression rose at PND1 but fell at PND9 and 21, whereas GPx1 expression was consistently reduced in the exposed group.

Exposure to 1.8 GHz radiofrequency field modulates ROS in human HEK293 cells as a function of signal amplitude

Unknown authors · 2022

Researchers exposed human HEK293 cultured cells to a 1.8 GHz carrier frequency at amplitudes typical of household telecommunications. ROS concentrations increased significantly after 15 minutes of exposure and were localized to both nuclear and cytosolic compartments. qPCR analysis revealed altered gene expression of anti-oxidative enzymes SOD, GPX, and CAT, and oxidative enzyme Nox-2. Multiple genes responsive to static magnetic fields were also regulated by RF, suggesting common response mechanisms. Many RF effects showed evidence of hormesis with biphasic dose-response curves and blind spots at certain amplitudes.

Investigation of oxidative damage, antioxidant balance, DNA repair genes, and apoptosis due to radiofrequency-induced adaptive response in mice

Unknown authors · 2022

The study used 24 adult male Swiss-Albino mice divided into Four groups of 6. The radiofrequency and adaptive response groups were exposed to a 900 MHz GSM signal at 0.339 W/kg for 4 h/day over 7 days. After the final exposure, bleomycin was injected intraperitoneally at 37.5 mg/kg and the mice were sacrificed 30 minutes later. Oxidative damage and antioxidant mechanisms were examined in blood, DNA-repair gene expression was measured in liver, and apoptosis was assessed in liver using the TUNEL method. The adaptive response group showed increased ROS and p53 and OGG-1 expression, decreased SOD, CAT and TAC levels, and reduced apoptosis.

Gupta V, Srivastava R. 2.45 GHz microwave radiation induced oxidative stress: Role of inflammatory cytokines in regulating male fertility through estrogen receptor alpha in Gallus gallus domesticus

Unknown authors · 2022

Researchers exposed two-week-old immature male chickens to non-thermal low-level 2.45 GHz microwave radiation for two hours per day over 30 days. Exposed chickens showed decreased testicular weight, volume, and gonado-somatic index, as well as a substantial reduction in seminiferous tubule diameter. Radiation exposure increased oxidative stress parameters, increased IL-1β immunoreactivity, decreased IL-10 immunoreactivity, and reduced ERα expression in testes.

Evaluation of Cell Migration and Cytokines Expression Changes under the Radiofrequency Electromagnetic Field on Wound Healing In Vitro Model

Costantini E et al. · 2022

The study aimed to explore the therapeutic potential of different RF-EMF exposure setups to drive faster healing by evaluating keratinocyte migration, cytokines, and MMP expression. RF-EMF treatment promoted keratinocytes' migration and regulated the expression of genes involved in healing, such as MMPs, tissue inhibitors of metalloproteinases, and pro/anti-inflammatory cytokines, to improve WH.

Effect of Duration of Mobile Phone Use on the Salivary Flow and Total Antioxidant Capacity of Saliva and Salivary Immunoglobulin A Level: A Cross- sectional Study

Unknown authors · 2022

Eighty-one students were categorized into three groups based on daily mobile phone use: less than 20 minutes, 20 to 60 minutes, and more than 60 minutes. Salivary flow rate, IgA, and thiol levels showed no statistically significant differences among the three groups. Malondialdehyde (MDA) levels differed significantly across groups, with a significant pairwise difference between the 20–60 minute and over 60 minute groups.

B. Blake Levitt, Henry C. Lai, Albert M. Manville. Effects of non-ionizing electromagnetic fields on flora and fauna, Part 3. Exposure standards, public policy, laws, and future directions. Rev Environ Health. 2021 Sep 27. doi: 10.1515/reveh-2021-0083

Unknown authors · 2021

The review examines government standards adopted for human exposures for their applicability to wildlife. It states that existing environmental laws such as the National Environmental Policy Act and the Migratory Bird Treaty Act should be strengthened and enforced, and new laws written for increasing EMF exposures. Radiofrequency radiation exposure standards warrant more stringent controls given 5G signaling characteristics, and no current standards take wildlife into consideration. Numerous studies indicate low-level EMF exposures have adverse effects on orientation, migration, reproduction, and other behaviors, and cyto- and geno-toxic effects have long been observed.

What is the radiation before 5G? A correlation study between measurements in situ and in real time and epidemiological indicators in Vallecas, Madrid

Isabel López et al. · 2021

Researchers surveyed 268 residents in a Madrid neighborhood surrounded by nine telephone antennas and took 105 electromagnetic radiation measurements with a spectrum analyzer and isotropic antenna both outside and inside homes. The study found statistically significant associations between radiation exposure and headaches, nightmares, dizziness, instability episodes, sleep duration, and tiredness parameters. Cancer prevalence in the study population was 5.6%, which is 10 times higher than the general Spanish population.

Lost opportunities for cancer prevention: historical evidence on early warnings with emphasis on radiofrequency radiation

Hardell & Carlberg · 2021

The paper discusses historical lessons from early warnings on cancer risks and lost prevention opportunities. It states that radiofrequency radiation has a cancer-causing effect and that decades of studies show increased human cancer risk. Based on three case-control studies of wireless phone use, the authors present a preventable fraction for brain tumors and note an increase in undefined brain tumors in Sweden, especially among ages 20–39, which they suggest may be linked to high wireless phone use among young people.

(2021) Effects of mobile phone usage on sperm quality – No time-dependent relationship on usage: A systematic review and updated meta-analysis

Kim et al · 2021

The authors conducted a systematic review and updated meta-analysis following PRISMA guidelines. They evaluated 18 studies comprising 4280 samples. The outcome measures were sperm motility, viability, and concentration. Exposure to mobile phones was associated with reduced sperm motility, viability, and concentration. The decrease in sperm quality after RF-EMW exposure was not significant even when mobile phone usage increased.

(2021) Effects of electromagnetic fields on neuronal ion channels: a systematic review

Bertagna et al · 2021

The review systematically examined published evidence from the last two decades on EMF effects on neuronal ion channels per PRISM guidelines. The review included 22 papers identified from searches of three online databases. Changes in calcium homeostasis linked to voltage-gated calcium channels were the most frequently reported outcome of EMF exposure. The authors reported that EMF effects on neurons vary widely and depend on field frequency, exposure duration, and tissue properties such as voltage-gated channel expression.

The Time-Dependence of Three Different Modes of ELF-EMF Stimulation on LTP at Schaffer Collateral-CA1 Synapses

Unknown authors · 2021

Researchers exposed hippocampal slices from Sprague-Dawley rats to 15 Hz/2 mT ELF-EMF in three modes (sinusoidal, single-frequency pulse, and rhythm pulse) for durations of 10, 20, 40, and 60 seconds. LTP was induced with 100 Hz high-frequency stimulation and measured via fEPSP recordings for 60 minutes using multi-electrode arrays after a 20-minute baseline. Compared to controls, all three ELF-EMF modes decreased LTP, and the inhibition increased with longer exposure durations. The continuous sinusoidal field produced the largest inhibitory effect, while the pulsed and rhythm-pulsed fields had similar effects.

Short-Term Extremely Low-Frequency Electromagnetic Field Inhibits Synaptic Plasticity of Schaffer Collateral-CA1 Synapses in Rat Hippocampus via the Ca 2+ /Calcineurin Pathway

Xia P, Zheng Y, Dong L, Tian C · 2021

Researchers investigated the effect of sinusoidal ELF-EMF on HeLa, ES-2, and DU-145 cancer cells. The exposure used a 50 Hz field at 1.3 mT for 15 and 30 minutes. ELF-EMF treatment raised reactive oxygen species levels in the cells. ES-2 cells showed upregulation of XRCC5 and increased TNF-α, RAD51, APE1, XRCC1, and NSUN2, while DU-145 cells had decreased BCL-2, HSP90, RAD51, and TNF-α and increased VIM and METTL3.

Static magnetic field induces abnormality of glucose metabolism in rats' brain and results in anxiety-like behavior

Shuo T et al. · 2021

Fifty-four male Wistar rats were randomly divided into four groups (control, low-intensity, moderate-intensity, and high-intensity) and exposed to static magnetic fields of 50 m T, 100 m T, and 200 m T for 1 hour per day over 15 consecutive days. Micro-PET imaging showed that moderate-intensity static magnetic fields could cause fluctuant changes in brain glucose metabolism that were intensity dependent. Western blot analysis detected the expression of HK1 and PFK1, and both enzymes significantly decreased after exposure. Open field testing revealed significant reductions in total distance, surrounding distance, activity time, and climbing and standing times. Brain histology after 15 exposures showed neuronal pyknosis, edema, and slight widening of the perivascular space.

Brain & Nervous System
Not an original health-effects study

Occupational Exposure to Extremely Low-Frequency Magnetic Fields and Risk of Amyotrophic Lateral Sclerosis: Results of a Feasibility Study for a Pooled Analysis of Original Data

Unknown authors · 2021

Researchers conducted a systematic literature search in PubMed and EMF-Portal through January 2019 and identified 15 articles published between 1997 and 2019. Eight principal investigators expressed willingness to provide their original data for a pooled analysis. A pooled study would have more than 80% power to detect a relative risk of 1.14 or higher for ALS and occupational ELF-MF exposure.

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