Zook BC,Simmens SJ. · 2006
Researchers exposed offspring of pregnant rats treated with ENU to pulsed RF signal for 6 hours per day, 5 days per week. The 1080 rats were randomized into pulsed RF, sham, and cage control groups. Postmortem examination found no effect of RF exposure on incidence, malignancy, volume, multiplicity, latency, or fatality of any neurogenic tumor.
Vangelova K, Deyanov C, Israel M. · 2006
The study aimed to assess long-term effects of radiofrequency electromagnetic radiation on the cardiovascular system. Researchers studied two exposed groups of broadcasting and TV station operators and a control group of radiorelay station operators matched by sex and age. Systolic and diastolic blood pressure, total cholesterol, and low-density lipoprotein cholesterol were significantly higher in the exposed groups. Radiofrequency EMR exposure was associated with a greater chance of becoming hypertensive and dyslipidemic. The authors concluded that radiofrequency EMR contributes to adverse cardiovascular effects.
Keshvari J, Keshvari R, Lang S. · 2006
Keetley V, Wood AW, Spong J, Stough C. · 2006
The study compared the performance of 120 volunteers on eight neuropsychological tests during real or sham exposure to a digital mobile phone at maximum permissible radiofrequency power output. Results were adjusted for gender, age, and education, revealing several alterations at p<0.05. Simple and choice reaction times showed strong evidence of impairment. Trail Making Task performance improved, supporting the hypothesis that digital mobile phone radiofrequency emissions improve the speed of processing of information held in working memory.
Hamann W, Abou-Sherif S, Thompson S, Hall S. · 2006
Researchers applied pulsed radiofrequency (20 ms of 500-kHz RF pulses at 2 Hz, max 42°C) to the sciatic nerve or L4 anterior primary ramus in adult rats. Controls included sham-operated and L4 axotomised rats, and tissues were examined 14 days later. Axotomy upregulated ATF3 in L4 DRG neurons regardless of size. PRF applied near the DRG significantly and selectively increased ATF3 in small and medium neurons, while PRF applied to the sciatic nerve in mid-thigh caused no obvious changes.
Faucon G, Le Bouquin Jeannes R, Maby E. · 2006
Nine healthy subjects and six temporal epileptic patients were exposed to radiofrequencies emitted by a GSM mobile phone while EEG signals were recorded with surface electrodes. For healthy subjects, EEG spectral energy decreased on the studied frequency band [0-40 Hz] and more precisely on occipital electrodes for the alpha-band. For epileptic patients, modifications were demonstrated by an increase of the power spectral density of the EEG signal. The authors noted that these biological effects on the EEG are not sufficient to put forward an electrophysiological hypothesis.
Eliyahu I et al. · 2006
Thirty-six healthy right-handed men performed four cognitive tasks under right-side, left-side, and sham exposure conditions. The study used a standard GSM phone at 890 MHz operated at full power via a base station simulator. Left-side exposure slowed left-hand response time in the later experimental period, an effect seen in three of four tasks but highly significant in only one. The exposure intensity and duration exceeded typical cell phone user exposure.
Cooper TG, Mann SM, Khalid M, Blackwell RP. · 2006
The study assessed exposures of the general public to radio waves near 20 randomly selected GSM microcell and picocell base stations in the UK against ICNIRP guidelines. Exposures were generally in the range 0.002% to 2% of the ICNIRP general public reference level, with the greatest exposure quotient near any base station being 8.6%. Exposures close to microcell base stations were generally greater than those close to macrocell base stations.
Burch JB et al. · 2006
Researchers quantified RF exposures among 280 residents living near Denver broadcast transmitters. RF power densities were measured outside and inside homes, and GPS and GIS view-shed models characterized distance, elevation, and transmitter visibility. Over a 2.5-day period, mean residential RF levels did not differ overall, but RF levels varied considerably among some homes. After a 1- to 2-year follow-up, only 25% of exterior and 38% of interior RF measurements remained unchanged. Homes with more than 50% of transmitters visible at distances of 1-3 km had exterior RF measurements 13-30 times greater than homes with less visibility.
Anghileri LJ, Mayayo E, Domingo JL, Thouvenot P. · 2006
The study aimed to evaluate health risks caused by radio frequency accelerated carcinogenesis and the importance of processes driven by the calcium ion signal. Exposed animals showed organ hypertrophy, lymphoid blood and ascites, solid tumours, and mortality that were very different from control animals. The results emphasized the role of calcium ion signal influx in the activation of oncogenes and the failure of thymus-determined immune defences.
Anghileri LJ, Mayayo E, Domingo JL. · 2006
The study investigated the effects of parenteral iron administration on the acceleration of lymphomagenesis by radiofrequency exposure using an animal model that develops spontaneous lymphomas with ageing. Complementary studies showed differences in absorption and excretion between ferric gluconate and ferric-ATP complex, and molecular structure-dependence in calcium cellular uptake. The results demonstrated a synergism between radiofrequency and ferric gluconate, and increased risk of radiofrequency exposure when simultaneous to parenteral iron administration.
Zhao R, Zhang SZ, Yao GD, Lu DQ, Jiang H, Xu ZP · 2006
Zeng Q, Chen G, Weng Y, Wang L, Chiang H, Lu D, Xu Z. · 2006
Researchers investigated gene and protein responses to GSM 1800 MHz RF EMF in human breast cancer MCF-7 cells using genomic and proteomic approaches. GeneChip analysis identified a handful of changed genes after exposure at SAR up to 3.5 W/kg for 24 hours, but these changes were not confirmed by RT-PCR. Proteome analysis found a few different proteins differentially expressed under continuous or intermittent exposure at SAR 3.5 W/kg for 24 hours or less, but the authors suggest these effects might have occurred by chance.
Zeng QL, Weng Y, Chen GD, Lu DQ, Chiang H, Xu ZP · 2006
Researchers exposed MCF-7 human breast cancer cells to GSM 1800 MHz RF EMF at 3.5 W/kg SAR for various durations and modes. They used 2-dimensional electrophoresis and PDQuest software to analyze protein expression. No differential proteins were found after 6 hours of continuous exposure. Eighteen differential proteins were detected after 3-hour intermittent exposure and seven after 12-hour continuous exposure. The analysis suggested that the differentially expressed proteins should be related to biosynthesization, signal transduction, and DNA damage and repair.
Vanderwaal RP, Cha B, Moros EG, Roti Roti JL. · 2006
The radiofrequency exposures were 847 MHz TDMA at a SAR of 5 W kg-1 for 1, 2, or 24 h and 900 MHz GSM at a SAR of 3.7 W kg-1 for 1, 2, or 5 h. Acute hyperthermia at 45 degrees C increased the proportion of higher phosphorylated forms of HSP27. Exposure of HeLa S3 cells to 5 W kg-1 TDMA for 1, 2, or 24 h did not induce significant differences in HSP27 phosphorylation compared to incubator control or sham.
Takashima Y et al. · 2006
Researchers exposed cells to radio frequency electromagnetic fields at 2.45 GHz to examine cell growth, survival, and cell cycle distribution across a wide range of specific absorption rates. When cells were exposed to a continuous RF field at SARs from 0.05 to 100 W/kg for 2 h, cellular growth rate, survival, and cell cycle distribution were not affected. At 200 W/kg, the cell growth rate was suppressed and cell survival decreased, and the temperature of the medium rose to 44.1 degrees C. The researchers suggested that the proliferation disorder is caused by the thermal effect.
Hoyto A, Sihvonen AP, Alhonen L, Juutilainen J, Naarala J · 2006
Researchers investigated the effects of low-level radiofrequency radiation and elevated temperature on ornithine decarboxylase (ODC) activity in murine L929 fibroblasts. RF radiation did not affect cellular ODC activity. A slight temperature increase of 0.8-0.9 degrees C in the exposure system led to decreased ODC activity, which was verified by exposing cells to different temperatures in incubators.
Henderson SI, Bangay MJ. · 2006
Researchers measured radiofrequency signals from 60 base stations across five Australian cities at distances ranging from 50 to 500 m. All recorded exposure levels were well below the general public exposure limits of the ICNIRP guidelines and the Australian radiofrequency standard (ARPANSA RPS3). The highest level recorded from any single base station was 7.8 x 10(-3) W/m(2), which translates to 0.2% of the general public exposure limit.
Faraone et al. · 2006
Capri M et al. · 2006
Researchers exposed human peripheral blood mononuclear cells from young and elderly donors to radiofrequency radiation at 1,800 MHz and a Specific Absorption Rate of 2 W/kg, with or without mitogenic stimulation. However, RF exposure produced a slight but significant downregulation of CD95 expression in stimulated CD4+ T lymphocytes from elderly donors only.
Wilen J, Johansson A, Kalezic N, Lyskov E, Sandstrom M · 2006
Researchers investigated the effect of a mobile phone-like radiofrequency electromagnetic field on people who reported subjective symptoms when using mobile phones. Twenty subjects with mobile phone-related symptoms were matched with 20 controls without such symptoms, and each person took part in one true exposure session and one sham exposure session in random order. No significant differences related to radiofrequency exposure conditions were detected. The symptomatic group displayed a shift in low/high frequency ratio towards sympathetic dominance in the autonomous nervous system during tests, regardless of exposure condition.
Zhang DY, Xu ZP, Chiang H, Lu DQ, Zeng QL. · 2006
Researchers studied the effects of GSM 1800 MHz radiofrequency electromagnetic fields on DNA damage in Chinese hamster lung cells. Cells were intermittently exposed to GSM 1800 MHz RF EMF at a SAR of 3.0 W/kg for either 1 hour or 24 hours, using a pattern of 5 minutes on and 10 minutes off. After 24 hours of exposure, the percentage of gammaH2AX foci positive cells was 37.9 +/- 8.6%, significantly higher than the sham-exposed group at 28.0 +/- 8.4%. The 1-hour exposure showed no significant difference from sham exposure.
Lixia S et al. · 2006
Researchers exposed human lens epithelial cells (hLEC) to a 1.8 GHz GSM radiofrequency field at SARs of 1, 2, and 3 W/kg for 2 hours and then measured DNA damage, Hsp70 expression, and cell proliferation. DNA breaks at 1 and 2 W/kg were not significantly different from controls at any time point, while the 3 W/kg dose showed significantly increased DNA damage only at 0 and 30 minutes after exposure. Hsp70 protein expression was significantly increased at 2 and 3 W/kg, but Hsp70 mRNA expression did not change in any group, and cell proliferation was unaffected at all doses.
Whitehead TD et al. · 2005
The study aimed to confirm a previous report that CDMA and FDMA radiation increased Fos levels as cells entered plateau phase. Fos mRNA levels were not significantly different from sham exposure at either SAR level for any signal modulation. Therefore, the earlier results could not be confirmed.
Straume A, Oftedal G, Johnsson A · 2005
One healthy male subject participated in the study. The subject held the phone in a normal position while the phone was off, on with a 50 Ohm load replacing the antenna to remove RF exposure, and on while transmitting RF fields. The phone’s output power was set to its minimum and maximum levels. The experiment was double blind. Skin temperature changes were calculated on the exposed side of the head relative to the unexposed side after 15 and 30 minutes of use.