Nam KC, Lee JH, Noh HW, Cha EJ, Kim NH, Kim DW. · 2009
Researchers tested 18 self-reported EHS and 19 non-EHS volunteers with sham and real RF exposure from CDMA cellular phones at 300 mW maximum for half an hour. They measured heart rate, respiration rate, heart rate variability, subjective symptoms, and EMF perception. RF exposure had no effect on physiological parameters or subjective symptoms in either group.
Mizuno Y et al. · 2009
This was the first study to investigate the effects of the third generation system on regional cerebral blood flow in humans, comparing W-CDMA electromagnetic field exposure versus sham exposure. Nine healthy male volunteers participated and underwent PET scans before, during, and after 30 minutes of unilateral EMF exposure. The subtraction analysis showed no significant regional cerebral blood flow changes from the EMF conditions compared to sham exposure.
Marino AA, Carrubba S · 2009
The authors analyzed 55 reports that compared human brain electrical activity with and without mobile-phone electromagnetic fields or before and after exposure. Positive reports failed to adequately address family-wise error rates, spike artifacts, and the confounding influence of two different EMFs, while negative reports lacked positive controls and power analyses. The reviewers concluded that the crucial question of how mobile-phone EMFs affect brain activity remains unanswered and essentially unaddressed.
Lee HJ, Lee JS, Pack JK, Choi HD, Kim N, Kim SH, Lee YS. · 2009
Researchers investigated the teratogenic effects of multi-signal radiofrequency electromagnetic fields on mouse fetuses. Pregnant mice were simultaneously exposed to CDMA and WCDMA signals for two 45-minute periods daily throughout gestation at a whole-body average SAR of 2.0 W/kg. Fetuses were examined on gestation day 18 for mortality, growth retardation, head size changes, and morphological abnormalities, and no adverse effects were observed.
Hansteen IL et al. · 2009
The aim was to test if exposure used in mobile phones and wireless network technologies would induce DNA damage in cultured human lymphocytes with and without a known clastogen. Lymphocytes from six donors were exposed to 2.3 GHz, 10 W/m(2) continuous waves, or 2.3 GHz, 10 W/m(2) pulsed waves (200 Hz pulse frequency, 50% duty cycle). Mitomycin C was added to half of the cultures. No statistically significant differences were observed between control and exposed cultures. A weak trend for more chromosomal damage with the interaction of pulsed fields with mitomycin C compared to a constant field was observed.
Hansteen IL et al. · 2009
Researchers exposed lymphocytes from two smoking and four non-smoking donors for 53 hours to 1.0 W/m(2) continuous-wave at 18.0 GHz or 10 W/m(2) pulsed-wave at 16.5 GHz, alone or with MMC. DNA synthesis and repair were inhibited in some cultures. No synergistic effect was observed with MMC or with cells pre-exposed to tobacco smoke. A non-significant trend toward increased aberration frequencies appeared for 16.5 GHz pulsed exposure in DNA synthesis and repair inhibited cultures. Neither exposure induced statistically significant increases in chromosomal aberration frequencies.
de Gannes FP et al. · 2009
The study aimed to confirm earlier Russian and Ukrainian data on 2450 MHz microwave effects on immunological processes and teratology in rats. All results using ELISA and classic teratology end points were negative. The researchers concluded that exposure at 2450 MHz, CW, 7h/day for 30 days at 0.16 W/kg whole-body SAR had no influence on several immune and degenerative parameters or prenatal development.
Billaudel B, Taxile M, Ruffie G, Veyret B, Lagroye I. · 2009
Researchers exposed murine L-929 fibroblasts to DAMPS and GSM signals at various SARs using different exposure set-ups and measured ODC activity via 14CO2 generation from 14C-labeled L-ornithine. Exposure to 50 Hz-modulated DAMPS-835 at 2.5 W/kg for one hour in TEM cells and at 6 W/kg with temperature control showed no significant alteration in ODC activity. In the second part, no alteration of ODC activity was detected with 217 Hz modulated GSM-900 (wire-patch antenna) or GSM-1800 (waveguides) when cells were lysed before measurement. The researchers concluded that under their exposure conditions, DAMPS-835 and GSM signals have no influence on ODC activity in L-929 cells.
Billaudel B et al. · 2009
Researchers exposed human SH-SY5Y neuroblastoma cells to DAMPS and GSM signals using waveguide systems. No change in ODC activity was observed regardless of signal type, duration, or SAR.
Ahlbom A et al. · 2009
The review summarizes epidemiologic evidence on whether radiofrequency fields from mobile phones cause tumors. Studies to date do not show an increased risk of any brain or head tumor within roughly 10 years of use. Data do not suggest a causal link for fast-growing tumors like malignant glioma, but conclusions for slow-growing tumors and long-term use are less certain due to short observation periods.
Sannino A et al. · 2009
Researchers exposed human dermal fibroblasts from a healthy donor and a Turner's syndrome donor to 900 MHz RF radiation for 24 hours using a GSM-like signal at 1 W/kg, and Turner's syndrome fibroblasts were also exposed for 1 hour. For RF exposure alone, DNA damage was assessed with the alkaline comet assay and the cytokinesis-block micronucleus assay. RF radiation alone caused no genotoxic or cytotoxic effects in either cell line. MX increased DNA migration in the comet assay, but RF exposure did not enhance this MX-induced DNA damage.
Furubayashi T et al. · 2009
Researchers conducted a double-blind, cross-over study with 11 women reporting mobile phone related symptoms and 43 control women. Participants were exposed to 2.14 GHz W-CDMA fields at 10 V/m for 30 minutes under continuous, intermittent, and sham conditions. The symptom group did not detect real exposure better than controls but reported more discomfort during both real and sham exposure, with no differences in psychological, cognitive, or autonomic measures.
Güler G, Türközer Z, Ozgur E, Seyhan N. · 2009
Researchers exposed subjects to a 50 Hz, 12 kV/m electric field for 7 days at 8 hours per day and measured pulmonary levels of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline. Protein carbonyl content increased significantly with electric field exposure compared to controls, while the other four markers showed no significant change. Adding the antioxidants NAC or EGCG during exposure did not produce significant changes in any of the measured parameters compared to electric field exposure alone.
Güler G, Türközer Z, Ozgur E, Tomruk A, Seyhan N, Karasu C · 2009
Researchers exposed guinea pigs to a 50 Hz, 12 kV/m electric field for 7 days, 8 hours per day, and measured protein carbonyl content (PCO), advanced oxidation protein products (AOPP) in liver, and 3-nitrotyrosine (3-NT) in plasma. They also assessed hepatic hydroxyproline levels to study protein synthesis. Exposure to the electric field did not significantly change PCO, AOPP, or 3-NT levels compared to controls. However, liver hydroxyproline was significantly reduced in the exposed group. N-acetyl-L-cysteine (NAC) administration significantly altered PCO, hydroxyproline, and 3-NT levels.
Aldinucci C et al. · 2009
Researchers exposed synaptosomes to a peak magnetic field of 2 mT for 2 hours. They evaluated mitochondrial respiration rate, ATP production, membrane potential, intrasynaptosomal calcium concentration, and release of free iron and F2-isoprostanes. Oxygen consumption and ATP production remained unchanged in exposed synaptosomes. Intrasynaptosomal calcium concentration decreased slowly with no membrane depolarization detected, and free iron and F2-isoprostane release remained unchanged.
Söderqvist F, Carlberg M, Hardell L · 2009
One thousand subjects, 500 of each sex aged 18–65 years, were randomly recruited using the population registry and assessed via postal questionnaire and blood samples for S100B. The response rate was 31.4%. The study failed to show that long- or short-term use of wireless telephones was associated with elevated serum S100B levels. The linear regression analysis of latency for UMTS use remained significant only for men (p = 0.01; n = 31). Total use of mobile and cordless phones over time yielded an odds ratio of 0.8 (95% CI 0.3–2.0) and same-day use yielded an odds ratio of 1.1 (95% CI 0.4–2.8).
Rağbetli MC, Aydinlioğlu A, Koyun N, Rağbetli C, Karayel M. · 2009
The study examined the effect of mobile phone exposure on the developing hippocampus in Swiss albino mice. Pregnant mice were exposed to a mobile phone in an exposure system room. Pyramidal cells in the hippocampus were counted using the optical fractionator method with Axiovision software. No significant difference in pyramidal cell numbers was found between exposed and control groups.
Parazzini M et al. · 2009
Participants received 20 minutes of genuine or sham RF exposure at maximum phone output with 69 mW/kg SAR in the cochlea region. Auditory function was measured before and after exposure using hearing thresholds, otoacoustic emissions, and auditory evoked potentials. No consistent pattern of effects was found, and an isolated high-frequency threshold change was not statistically significant after multiple comparison correction. Researchers concluded that short-term UMTS exposure at maximum consumer phone output does not cause measurable immediate auditory effects.
Ogawa K et al. · 2009
The study exposed four groups of pregnant CD(SD) IGS rats to a 1.95-GHz W-CDMA signal for 90 minutes daily on gestational days 7–17, with spatial average brain SARs of 0.67 and 2.0 W/kg for low and high exposure groups. On gestational day 20, all dams were killed by cesarean section and fetuses were evaluated for numbers of live, dead, and resorbed embryos, placental weights, sex ratios, fetal weights, and external, visceral, and skeletal abnormalities. Maternal body weight gain did not differ between groups, and no adverse effects were observed on any reproductive or embryotoxic parameters.
Lipping T et al. · 2009
Eleven pigs were anaesthetized to a burst-suppression EEG level and exposed to a GSM mobile phone signal at 890 MHz. In phase I, EMF stimulation was randomly switched on and off to study the relation between EEG bursts and EMF onsets and endpoints. In phase II, continuous RF stimulation at 31 W/kg was applied for 10 minutes while ECG, EEG, and subcutaneous temperature were recorded. No correlation between exposure and EEG burst occurrences was observed in phase I, and no significant EEG changes were found in phase II. Subcutaneous temperature increased by 1.6°C and heart rate by 14.2 bpm on average during the 10-minute exposure periods.
Kwon MS et al. · 2009
Researchers recorded mismatch negativity responses to duration, intensity, frequency, and gap changes in 17 healthy young adults while a GSM phone was placed on either ear with the field on or off. The mismatch negativity was elicited by all deviant types, but its amplitude and latency showed no significant differences due to EMF exposure for any deviant type. The authors concluded there was no conclusive evidence that acute GSM mobile phone EMF exposure affects cortical auditory change detection processing reflected by the mismatch negativity.
Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z · 2009
Researchers exposed pregnant mice to 900 MHz radiofrequency fields at 4 W/kg for 60 minutes daily throughout gestation. Fetal brains were examined for heat shock proteins HSP25, HSP32, and HSP70. No induction of HSP32 or HSP70 was found in any brains, and HSP25 expression was similar in exposed and control groups. The study concluded that whole-gestation exposure did not produce a stress response detectable by HSPs.
Finnie JW, Blumbergs PC, Cai Z, Manavis J · 2009
Researchers exposed mice to 900 MHz radiofrequency fields at a specific absorption rate of 4 W/kg for 60 minutes or for 5 days per week over 104 weeks. Control mice were sham-exposed or freely moving to account for restraint stress, and a positive control group received a clostridial toxin that upregulates aquaporin-4. No immunohistochemically detectable up-regulation of aquaporin-4 was observed in exposed mouse brains after either short or long exposure durations.
Eltiti S et al. · 2009
Researchers exposed 44 sensitive and 44 matched-control participants to GSM, UMTS, and sham signals for 50 minutes at 10 mW/m2 under double-blind conditions. Participants performed digit symbol substitution, digit span, and mental arithmetic tasks during exposure. Cognitive functioning and physiological measures including blood volume pulse, heart rate, and skin conductance were not affected by exposure.
de Gannes FP et al. · 2009
In the study, 16 Fischer 344 rats (14 weeks old) were exposed head-only to the GSM-900 signal for 2 h at various brain-averaged SARs (0, 0.14 and 2.0 W/kg) or were used as cage or positive controls. Albumin leakage and neuron degeneration were evaluated 14 and 50 days after exposure. No statistically significant albumin leakage was observed. Neuronal degeneration assessed using cresyl violet or Fluoro-Jade B was not significantly different among the tested groups. No apoptotic neurons were found 14 days after the last exposure using the TUNEL method.
