Wang J, Su H, Xie W, Yu S. · 2017
Researchers performed a systematic review and meta-analysis of 7 cross-sectional studies on MP use and headache. The pooled analysis found a 38% increased risk of headache in MP users versus non-MP users. Among MP users, longer daily call duration and higher daily call frequency were each associated with greater headache risk.
Sato Y, Kojimahara N, Taki M, Yamaguchi N · 2017
The study aimed to clarify the distribution of ear side of mobile phone use in Japan and factors associated with it. Statistically significant differences were observed only in talk time per call with an odds ratio of 2.17 and a 95% confidence interval of 1.22 to 3.99. In right-handed adults, left-ear use was significantly associated with age groups 30-39 (OR = 2.55; 95% CI: 1.79-3.68), 40-49 (OR = 3.08; 95% CI: 2.15-4.43), over 50 (OR = 1.85; 95% CI: 1.20-2.85), and with work-related talk time of 51-100% (OR = 1.75; 95% CI: 1.21-2.55). The survey included 2,518 children and 1,529 adults who completed an Internet-based survey, and data were analyzed by logistic regression. In children, the analysis focused on right-ear use in right-handed individuals due to dominant-hand tendency.
Lee AK, Hong SE, Kwon JH, Choi HD, Cardis E. · 2017
Researchers calculated specific absorption rate for four anatomical head models at different ages using 11 numerical phone models of different shapes and antenna configurations. The 11 models represented phone types accounting for around 86% of the approximately 1400 commercial phone models released into the Korean market since 2002. Seven of the phone models selected had an internal dual-band antenna and the remaining four had an external antenna. The 1 g peak spatial SAR and ipsilateral and contralateral brain-averaged SARs were reported for all 11 phone models, and the effects of phone type, phone position, operating frequency, and age of head models on brain SAR were comprehensively determined.
Ibitayo AO et al. · 2017
Researchers divided young male rats into four groups, with three groups exposed to 2.5 Ghz radiation for 30, 45, or 60 consecutive days. DNA damage was detected using agarose gel electrophoresis, and histomorphometry showed perivascular congestion and tissue damage.
Hardell L, Carlberg M. · 2017
Researchers analyzed brain tumor rates in the Swedish National Inpatient Register and Swedish Cancer Register from 1998 to 2015. The average annual percentage change for brain tumors increased by 2.06% per 100,000 in both genders combined. A joinpoint in 2007 showed a shift from a 0.16% annual change before 2007 to a 4.24% annual change after 2007. The highest increase was in the 20-39 year age group. The authors concluded that underreporting to the Cancer Register means real incidence is higher and trends should be used with caution.
Eghlidospour M, Ghanbari A, Mortazavi SMJ, Azari H. · 2017
Researchers exposed adult murine neural stem cells to GSM 900-MHz radiofrequency radiation from a mobile phone for varying durations. They used neurosphere assays to evaluate proliferation, immunofluorescence to examine differentiation, and alamarBlue and caspase 3 apoptosis assays to assess harmful effects. Neurosphere number and size and the proportion of cells becoming neurons decreased significantly with longer exposure. Cell viability, apoptosis, and astrocytic differentiation were unchanged.
Durusoy R, Hassoy H, Özkurt A, Karababa AO. · 2017
Headache, fatigue, and sleep disturbances were reported 1.90, 1.78, and 1.53 times more often among mobile phone users. Dose-response relationships were found for call frequency, call duration, text message frequency, phone position at night, and charging while calling with symptoms such as headache, concentration difficulties, fatigue, sleep disturbances, ear warming, and flushing. No association was found between school EMF levels and symptoms, while limited associations were seen for proximity to base stations. Data were collected via questionnaire and EMF measurements from November 2009 to April 2011 using an Aaronia Spectran HF-4060 device.
Carlberg M, Hardell L. · 2017
The authors evaluated glioma risk from mobile and cordless phone use using Bradford Hill's viewpoints. All nine viewpoints were evaluated based on epidemiology and laboratory studies. A meta-analysis of case-control studies found an odds ratio of 1.90 (95% CI 1.31-2.76) with highest cumulative exposure. Risk increased with latency, with an OR of 1.62 (95% CI 1.20-2.19) for 10+ years latency. Highest risk was in the 20+ years latency group, OR 2.01 (95% CI 1.41-2.88) for wireless phones.
Birks L et al. · 2017
Researchers analyzed data from 83,884 mother-child pairs across five birth cohorts in Denmark, Korea, the Netherlands, Norway, and Spain. They categorized maternal cell phone use during pregnancy into none, low, medium, and high based on call frequency reported by mothers. Child behavioral problems were assessed using the Strengths and Difficulties Questionnaire or Child Behavior Checklist at ages 5–7 years. A trend of increasing risk of hyperactivity/inattention problems was observed across cell phone use categories, with odds ratios of 1.11 for medium users and 1.28 for high users. The association was consistent across cohorts and between prospective and retrospective data collection methods.
Bhatt CR et al. · 2017
Aslan A, İkinci A, Baş O, Sönmez OF, Kaya H, Odacı E. · 2017
Researchers used three groups of six 21-day-old male rats, including an unexposed control, a sham-exposed group, and a group exposed to 900 MHz EMF for one hour daily from postnatal day 21 to 46. The EMF-exposed group had significantly fewer Purkinje cells than both the control and sham groups. Histopathological examination also showed altered Purkinje cell arrangement and intense cytoplasmic staining in the exposed rats.
Altuntas G et al. · 2017
The study was a single-center, prospective, randomized, double-blinded trial involving 30 emergency physicians randomly assigned to two groups. The control group held a mobile phone in 'off' mode to their left ear for 15 minutes, while the intervention group held a phone in 'on' mode, exposing them to 900-1800 MHz electromagnetic waves for the same period. Total performance, total figures marked, percentile, and attention fluctuation did not differ between groups, but the intervention group missed fewer figures, made fewer incorrect marks, and showed better focus.
Zheng Y, Ma W, Dong L, Dou JR, Gao Y, Xue J. · 2017
Researchers studied the influence of on-line ELF-EMF stimulation on electrophysiological properties of rat hippocampal CA1 neurons in vitro. Modeling data and actual measurements showed similar magnetic flux densities from the stimulation coils. The stimulator induced sodium channel currents and field excitatory postsynaptic potentials in the neurons. Computational simulations in COMSOL modeling described the uniformity of the on-line magnetic field distribution.
Zhen J, Qian Y, Fu J, Su R, An H, Wang W , Zheng Y, Wang X. · 2017
Researchers investigated the effect of deep brain magnetic stimulation on spatial learning and memory, neurogenesis in the dentate gyrus, and cholinergic system expression and activity in a transgenic 5XFAD mouse model. Deep brain magnetic stimulation improved spatial learning and memory, enhanced neurogenesis in the hippocampal dentate gyrus, raised acetylcholine levels, and prevented increased acetylcholinesterase activity and decreased acetyltransferase activity in the hippocampus of 5XFAD mice. The authors concluded that deep brain magnetic stimulation may be a promising noninvasive tool for treating and preventing Alzheimer's disease cognitive impairment by promoting neurogenesis and enhancing cholinergic function.
Sakhaie MH et al. · 2017
ELF-EMF exposure enhanced spatial learning and memory in the Morris water maze test. ELF-EMF significantly increased BrdU+ and NeuN+ cells in the dentate gyrus. Western blot showed NeuroD2 upregulation in ELF-EMF-exposed mice versus the TMT-treated group.
Koeman T et al. · 2017
Researchers conducted a case-cohort analysis within the prospective Netherlands Cohort Study, following men and women aged 55-69 at enrolment in 1986 for 17.3 years on ALS mortality. Occupational exposure to solvents, pesticides, metals, extremely low frequency magnetic fields, and electrical shocks was estimated using job exposure matrices. Occupational exposure to ELF-MF showed a possible association with ALS mortality among men, with a hazard ratio of 2.19 for ever holding a high-exposure job and 1.93 for the highest cumulative exposure tertile.
Haghighat N, Abdolmaleki P, Parnian J, Behmanesh M. · 2017
Dileone M et al. · 2017
Researchers performed a randomized double-blind sham-controlled cross-over study applying tSMS for 10 minutes to the more affected motor cortex of Parkinson's disease patients. Cortical excitability was measured by motor evoked potential amplitude elicited by single-pulse transcranial magnetic stimulation. tSMS significantly decreased MEP amplitudes in patients off dopaminergic medication but not in patients on levodopa. Between-patient variability of tSMS-induced changes was significantly greater when patients were on medication. Greater disease progression was associated with a switch from inhibitory to facilitatory plasticity on medication.
Clarke D et al. · 2017
Researchers tested four different repetitive magnetic stimulation frequencies on primary neonatal astrocyte cultures and measured calcium responses. Only 1 Hz stimulation produced a statistically significant rise in intracellular calcium in both cytoplasmic and nuclear compartments. This calcium increase did not change astrocyte migration or proliferation in a scratch assay. However, 1 Hz stimulation reduced astrocyte hypertrophy 24 hours after scratch injury. The authors concluded that the results provide preliminary evidence that repetitive magnetic stimulation can influence astrocyte physiology.
Carrasco-López C et al. · 2017
Researchers used noninvasive brain stimulation to modulate cortical network dynamics during neurophysiological and behavioral recordings. Parietal tSMS enhanced detection of near-threshold somatosensory stimuli. The improvement reflected decreased habituation to somatosensation. tSMS increased alpha oscillatory power without significantly affecting the early cortical component of somatosensory evoked potentials.
Varghese R, Majumdar A, Kumar G, Shukla A. · 2017
Researchers exposed female Sprague Dawley rats to 2.45GHz radiation for 4 hours per day for 45 days and assessed behavioral and oxidative stress parameters. Exposed rats exhibited memory decline and anxiety behavior in the Morris water maze, elevated plus maze, and light-dark box tests. Radiation exposure decreased brain antioxidant enzymes superoxide dismutase, catalase, and reduced glutathione, increased lipid peroxidation, and increased the apoptotic marker caspase 3, while histopathological examination and TNF-α levels showed no significant changes.
Othman H, Ammari M , Sakly M, Abdelmelek H. · 2017
Animals were divided into four groups: control, WiFi-exposed, restrained, and both WiFi-exposed and restrained, with each exposure occurring 2 h per day for 20 days. Tests included anxiety in the elevated plus maze, spatial learning in the water maze, cerebral oxidative stress response, and cholinesterase activity in brain and serum. WiFi exposure and restraint stress, alone and especially combined, induced anxiety-like behavior without impairing spatial learning and memory abilities. An oxidative stress response was triggered by WiFi and restraint, per se and especially when combined, as well as a WiFi-induced increase in acetylcholinesterase activity. There were no synergistic effects between WiFi signal and restraint stress on the brain.
Othman H et al. · 2017
Researchers exposed pregnant rats to a 2.45 GHz WiFi signal for two hours daily throughout gestation. Offspring were assessed for physical and neurodevelopment during the first 17 postnatal days, anxiety at 28 days, motor behavior at 40-43 days, and cerebral oxidative stress and cholinesterase activity at 28 and 43 days. Prenatal WiFi exposure impaired early neurodevelopment but did not alter emotional or motor behavior in adulthood. It also increased oxidative stress markers and decreased antioxidant enzyme activities at 28 days but not at 43 days, and affected acetylcholinesterase activity in brain and serum.
Bodera P et al. · 2017
Researchers evaluated the effect of repeated 1800 MHz RFR exposure (5 times for 15 min) on NMDA-NR1 expression in rat brains in a persistent inflammatory state. They also measured the effect of RFR combined with tramadol to determine its potential antioxidant capacity. No differences in NMDA-NR1 expression were observed between baseline and RFR-exposed groups. NMDA-NR1 expression decreased after CFA injection combined with RFR exposure, while elevated expression was observed in healthy control rats exposed to RFR with or without tramadol. ORAC assessment revealed a robust effect of RFR, but other experiments showed equivocal effects.
Xu F et al. · 2017