3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Influence of extremely low frequency magnetic fields on Ca2+ signaling and NMDA receptor functions in rat hippocampus

Manikonda PK et al. · 2007

Researchers exposed young rats to 50 Hz magnetic fields (the same frequency used in power lines) for 90 days and found significant changes in brain chemistry, specifically disrupted calcium signaling in the hippocampus, the brain region critical for memory and learning. The magnetic field exposure altered the activity of key enzymes and reduced the function of NMDA receptors, which are essential for memory formation. These findings suggest that chronic exposure to extremely low frequency magnetic fields may interfere with normal brain function and memory processes.

Effects of exposure to 50 Hz magnetic field of 1 mT on the performance of detour learning task by chicks

Che Y, Sun H, Cui Y, Zhou D, Ma Y. · 2007

Researchers exposed young chickens to power line magnetic fields for either 20 hours or 50 minutes daily, then tested their learning ability. Chicks with prolonged exposure showed significant learning problems, while brief exposure caused no harm, suggesting extended magnetic field exposure may impair brain function.

Pulsed radio-frequency electromagnetic fields: dose-dependent effects on sleep, the sleep EEG and cognitive performance.

Regel SJ et al. · 2007

Swiss researchers exposed 15 men to cell phone-like radiation at different intensities for 30 minutes before sleep, then monitored their brain activity and cognitive performance. They found that stronger radiation caused measurable changes in brain wave patterns during sleep and slowed reaction times on memory tasks. This demonstrates a dose-response relationship, meaning higher radiation exposure produces more pronounced effects on brain function.

Effects of GSM 1800 MHz on dendritic development of cultured hippocampal neurons.

Ning W, Xu SJ, Chiang H, Xu ZP, Zhou SY, Yang W, Luo JH · 2007

Researchers exposed developing rat brain cells to cell phone radiation and found that higher exposure levels (2.4 W/kg) significantly reduced the formation of dendritic spines, which are essential for brain cell communication, suggesting potential interference with normal brain development during critical growth periods.

Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs.

Meral I et al. · 2007

Researchers exposed guinea pigs to cell phone radiation for 12 hours daily over 30 days and measured brain tissue damage. They found increased oxidative stress (cellular damage from free radicals) in the brain, with higher levels of harmful compounds and lower levels of protective antioxidants. This suggests that prolonged cell phone radiation exposure may damage brain cells through oxidative stress mechanisms.

Mobile phone 'talk-mode' signal delays EEG-determined sleep onset.

Hung CS, Anderson C, Horne JA, McEvoy P · 2007

Researchers exposed 10 healthy young adults to different mobile phone signal modes for 30 minutes, then measured how long it took them to fall asleep. They found that exposure to 'talk mode' signals significantly delayed sleep onset compared to listening mode or no signal exposure. The study suggests that the specific signal patterns phones emit during calls may interfere with the brain's natural transition to sleep.

Studying gene expression profile of rat neuron exposed to 1800MHz radiofrequency electromagnetic fields with cDNA microassay.

Zhao R, Zhang S, Xu Z, Ju L, Lu D, Yao G. · 2007

Chinese researchers exposed rat brain neurons to cell phone-frequency radiation (1800 MHz) for 24 hours at power levels similar to heavy phone use. They found that 34 genes changed their activity levels, affecting how neurons function in areas like cell structure, communication, and metabolism. This demonstrates that radiofrequency radiation can alter the fundamental genetic programming of brain cells.

Radiofrequency radiation (900 MHz) induces Egr-1 gene expression and affects cell-cycle control in human neuroblastoma cells.

Buttiglione M et al. · 2007

Researchers exposed human brain cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) at power levels similar to what your phone emits. They found that this radiation activated stress response genes, disrupted normal cell division, and triggered cell death pathways. The effects occurred at radiation levels considered 'safe' by current standards, suggesting that RF exposure may interfere with fundamental cellular processes in brain tissue.

Cancer & TumorsNo Effects Found

Mobile phone use and acoustic neuroma risk in Japan.

Takebayashi T et al. · 2006

Japanese researchers studied 101 people with acoustic neuromas (benign tumors on the nerve connecting the ear to the brain) and compared their mobile phone use to 339 healthy controls. They found no increased risk of developing these tumors among mobile phone users, even those who used phones for over 8 years or accumulated more than 900 hours of call time. The study suggests mobile phone use does not significantly increase acoustic neuroma risk in Japan.

Brain & Nervous SystemNo Effects Found

Effects of thirty minutes mobile phone use on the human sensory cortex.

Yuasa K et al. · 2006

Japanese researchers tested whether 30 minutes of mobile phone use affects brain activity by measuring electrical signals in the sensory cortex (the brain region that processes touch and sensation) in 12 healthy volunteers. They found no changes in brain activity after phone exposure compared to fake exposure. This suggests that short-term mobile phone use doesn't immediately alter how your brain processes sensory information.

DNA & Genetic DamageNo Effects Found

Investigation of Co-genotoxic Effects of Radiofrequency Electromagnetic Fields In Vivo.

Verschaeve et al. · 2006

Researchers exposed female rats to mobile phone radiation (900 MHz) for 2 hours daily over 2 years, while also giving them a known cancer-causing chemical in their drinking water. They wanted to see if the radiation would make the chemical's DNA damage worse. The study found no evidence that the radiofrequency radiation enhanced the genetic damage caused by the toxic chemical.

Brain & Nervous SystemNo Effects Found

Exposure of Cultured Astroglial and Microglial Brain Cells to 900 MHz Microwave Radiation.

Thorlin et al. · 2006

Swedish researchers exposed brain glial cells (support cells that protect neurons) to 900 MHz radiation at various power levels for up to 24 hours to see if it would trigger inflammatory responses or cellular damage. They found no significant effects on inflammatory markers, cellular proteins, or cell structure at any exposure level tested. The study suggests that short-term exposure to 900 MHz radiation at these levels does not cause detectable damage to these important brain cells in laboratory conditions.

Brain & Nervous SystemNo Effects Found

Effects of thirty-minute mobile phone use on visuo-motor reaction time.

Terao Y, Okano T, Furubayashi T, Ugawa Y · 2006

Researchers tested whether 30 minutes of mobile phone use affects reaction time and movement speed in visual-motor tasks. In a well-designed study with 16 people, they found no differences in performance between real phone exposure and fake exposure. This suggests that short-term mobile phone use doesn't impair basic motor coordination or reaction speed.

Sleep & Circadian RhythmNo Effects Found

1800 MHz electromagnetic field effects on melatonin release from isolated pineal glands.

Sukhotina I, Streckert JR, Bitz AK, Hansen VW, Lerchl A · 2006

Researchers exposed isolated hamster pineal glands (which produce melatonin, the sleep hormone) to cell phone radiation at 1800 MHz for 7 hours at various power levels. Surprisingly, they found that moderate exposure levels actually increased melatonin production, while only the highest level (which caused tissue heating) suppressed it. This challenges the widely-discussed theory that cell phone radiation disrupts sleep by reducing melatonin.

Cancer & TumorsNo Effects Found257 citations

Cellular Telephone Use and Cancer Risk: Update of a nationwide Danish cohort.

Schüz J et al. · 2006

Danish researchers followed 420,095 cell phone subscribers for up to 21 years to see if mobile phone use increased cancer risk. They found no increased risk for brain tumors, acoustic neuromas, or other cancers typically associated with phone use, even among people who used phones for 10 years or more. This large-scale study suggests that cell phone use does not significantly increase cancer risk over the long term.

Cancer & TumorsNo Effects Found

Radiofrequency Electromagnetic Fields Emitted from Base Stations of DECT Cordless Phones and the Risk of Glioma and Meningioma (Interphone Study Group, Germany).

Schuz J et al. · 2006

German researchers studied 747 brain tumor patients and 1,494 healthy controls to see if sleeping near DECT cordless phone base stations increases brain tumor risk. They found no increased risk of glioma or meningioma brain tumors, with odds ratios of 0.82 and 0.83 respectively (values below 1.0 suggest slightly reduced risk). This provides initial evidence that low-level radiofrequency exposure from cordless phone base stations may not increase brain tumor risk.

Cancer & TumorsNo Effects Found245 citations

Cellular phones, cordless phones, and the risks of glioma and meningioma (Interphone Study Group, Germany).

Schuz J et al. · 2006

German researchers studied 747 brain tumor patients and 1,494 healthy controls to examine whether cell phone and cordless phone use increases the risk of glioma and meningioma (two types of brain tumors). While they found no overall increased risk from phone use, people who used cell phones for 10 or more years showed a 2.2-fold higher risk of glioma, though this finding wasn't statistically definitive. The results suggest potential long-term risks that require further investigation.

Brain & Nervous SystemNo Effects Found

Does acute exposure to mobile phones affect human attention?

Russo R et al. · 2006

Researchers tested 168 people on attention and cognitive tasks while exposed to mobile phone signals (both GSM and continuous wave) versus fake signals. They found no significant differences in performance on reaction time, vigilance, or mental math tasks regardless of which type of signal participants were exposed to or which side of the head the phone was positioned on.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.