8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 8,700 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 742 studies in Cancer & Tumors

The Apoptotic Effect of Caffeic or Chlorogenic Acid on the C32 Cells That Have Simultaneously Been Exposed to a Static Magnetic Field

Kimsa-Dudek M et al. · 2022

Researchers tested whether static magnetic fields combined with natural compounds (caffeic and chlorogenic acid) could kill melanoma cancer cells. They found that both the magnetic field and the plant compounds triggered cell death, with caffeic acid being more effective. This suggests magnetic fields might enhance natural cancer treatments.

Effects of prolonged exposure to ELF-EMF on HERVs expression in human melanoma cells

Karimi A, Ghadiri-Moghaddam F, Valipour M, Yahyavi Y · 2022

Researchers exposed human melanoma cells to power line frequency magnetic fields (50 Hz) for 96 hours and found it significantly reduced the activity of certain viral genes (HERVs) that are linked to cancer development. The study suggests this type of EMF exposure might have therapeutic potential for treating melanoma by suppressing these harmful viral elements.

2.4 GHz Electromagnetic Field Influences the Response of the Circadian Oscillator in the Colorectal Cancer Cell Line DLD1 to miR-34a- Mediated Regulation

Olejárová S, Moravčík R, Herichová I · 2022

Researchers exposed colorectal cancer cells to 2.4 GHz radiofrequency radiation (the same frequency as WiFi and Bluetooth) for 24 hours and found it disrupted the cancer-suppressing effects of a protective molecule called miR-34a. The radiation interfered with the cells' internal clock genes and allowed cancer cells to grow and spread more easily.

Cancer & Tumors100 citations

Molecular Mechanism of Malignant Transformation of Balb/c-3T3 Cells Induced by Long-Term Exposure to 1800 MHz Radiofrequency Electromagnetic Radiation (RF-EMR)

Ding Z, Xiang X, Li J, Wu S · 2022

This study exposed mouse Balb/c-3T3 cells to 1800 MHz radiofrequency electromagnetic radiation for 40-60 days and observed signs of malignant transformation, including increased cell proliferation, migration, visible foci formation, and tumor development when transplanted into SCID mice. The researchers identified lipid metabolism and the mevalonate pathway as key biological processes involved in the observed cellular changes.

Lost opportunities for cancer prevention: historical evidence on early warnings with emphasis on radiofrequency radiation

Hardell & Carlberg · 2021

This 2021 analysis by Hardell and Carlberg examines historical patterns of delayed cancer prevention, focusing on radiofrequency radiation from wireless devices. The researchers found increasing brain tumor rates in Sweden, particularly among 20-39 year olds, coinciding with widespread wireless phone adoption. They argue that current safety standards ignore non-thermal biological effects and call for proper health evaluation before 5G deployment.

Short-Term Extremely Low-Frequency Electromagnetic Field Inhibits Synaptic Plasticity of Schaffer Collateral-CA1 Synapses in Rat Hippocampus via the Ca 2+ /Calcineurin Pathway

Xia P, Zheng Y, Dong L, Tian C · 2021

This study examined the effects of short-term exposure to 50 Hz extremely low-frequency electromagnetic fields (ELF-EMFs) on cancer cells from gynecological and urological tissues. The researchers found that ELF-EMF exposure increased reactive oxygen species (ROS) levels and altered expression of genes and proteins involved in DNA damage response and epigenetic modifications, with the most significant changes observed in ovarian (ES-2) and prostate (DU-145) cancer cells after 30 minutes of exposure.

Changes in NOTCH1 gene and its regulatory circRNA, hsa_circ_0005986 expression pattern in human gastric adenocarcinoma and human normal fibroblast cell line following the exposure to extremely low frequency magnetic field

Mansoury F, Babaei N, Abdi S, Entezari M, Doosti A · 2021

Researchers exposed gastric cancer cells and normal cells to extremely low frequency magnetic fields at different strengths for 18 hours. The magnetic fields decreased cancer cell survival while increasing normal cell survival, and changed the expression of NOTCH1, a gene involved in cancer growth. This suggests ELF magnetic fields might selectively target cancer cells while protecting healthy tissue.

Pulsed and Discontinuous Electromagnetic Field Exposure Decreases Temozolomide Resistance in Glioblastoma by Modulating the Expression of O 6 -Methylguanine-DNA Methyltransferase, Cyclin-D1, and p53

Dehghani-Soltani S et al. · 2021

Researchers tested whether electromagnetic fields could help overcome chemotherapy resistance in aggressive brain cancer cells. They found that combining 50 Hz EMF exposure with the drug temozolomide killed more cancer cells and reduced their ability to spread. The electromagnetic fields appeared to make the chemotherapy more effective by changing how key cancer-related genes and proteins behaved.

Microarray profiling of LncRNA expression in the testis of pubertal mice following morning and evening exposure to 1800 MHz radiofrequency fields

Qin F, Cao H, Feng C, Zhu T, Zhu B, Zhang J, Tong J, Pei H · 2021

This study examined how radiofrequency field exposure at 1800 MHz affected testicular development in pubertal mice, comparing morning versus evening exposure times over three weeks. The researchers found that RF exposure reduced testicular weight, sperm production, and testosterone levels, while also altering long non-coding RNA (lncRNA) expression patterns that were associated with pathways involved in DNA damage, cell cycle regulation, and spermatogenesis.

Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice

Kim JH, Chung KH, Hwang YR, Park HR, Kim HJ, Kim HG, Kim HR · 2021

This study examined the effects of radiofrequency electromagnetic field (RF-EMF) exposure on developing hippocampal neurons in early postnatal mice exposed to 4.0 W/kg SAR for 5 hours daily over 4 weeks. The research found that RF-EMF exposure decreased dendritic spine density (particularly mushroom-type spines), reduced BDNF and glutamate receptor expression, hindered neurite outgrowth, and impaired memory function in exposed mice.

Cancer & Tumors418 citations

Microarray profiling of LncRNA expression in the testis of pubertal mice following morning and evening exposure to 1800 MHz radiofrequency fields

Qin F, Cao H, Feng C, Zhu T, Zhu B, Zhang J, Tong J, Pei H · 2021

This study exposed four-week-old mice to 1800 MHz radiofrequency fields for three weeks during morning and evening periods to investigate effects on testicular development. The exposure resulted in decreased testicular weight, sperm production, and testosterone levels, along with dysregulation of long non-coding RNA expression, with morning exposure affecting 615 lncRNAs compared to 183 for evening exposure.

Cancer & Tumors1,200 citations

Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence

Kim JH et al. · 2021

This study examined the effects of long-term evolution (LTE) radiofrequency electromagnetic fields (1760 MHz at 4 W/kg SAR) on neuroblastoma cell proliferation in SH-SY5Y cells. The researchers found that RF-EMF exposure decreased cell growth and proliferation by inducing cellular senescence through the Akt/mTOR pathway, which activated p53 and its downstream CDK inhibitors, ultimately delaying the cell cycle without causing DNA damage or apoptosis.

(2020) The association between smartphone use and breast cancer risk among Taiwanese women: A case-control study

Shih et al · 2020

Researchers studied 894 healthy women and 211 breast cancer patients in Taiwan to examine smartphone use habits. Women with smartphone addiction had 43% higher breast cancer risk, while using phones for more than 4.5 minutes before bedtime increased risk by 427%. Carrying phones near the chest or waist increased risk 4-5 times compared to carrying them below the waist.

Extremely Low Frequency Electromagnetic Fields Alter Expression of C- Myc and circ-CCDC66 in Gastric Cancer Cell Line

Mansoury F et al. · 2020

Researchers exposed stomach cancer cells to extremely low frequency magnetic fields and found the exposure altered expression of c-Myc (a gene linked to cancer progression) and circ-CCDC66 (a regulatory RNA molecule). The effects varied depending on field strength and whether exposure was continuous or intermittent, with some conditions reducing cancer-promoting gene activity while others increased it.

Evaluation of frequency magnetic field, static field, and Temozolomide on viability, free radical production and gene expression (p53) in the human glioblastoma cell line (A172) Electromagn Biol Med 39: 298-309, 2020

Ashta A , Motalleb G , Ahmadi-Zeidabadi M · 2020

Researchers tested whether magnetic fields could enhance the effectiveness of brain cancer treatment. They exposed human glioblastoma cells to 10 Hz and 50 Hz magnetic fields combined with the chemotherapy drug Temozolomide. The combination increased cancer cell death and activated tumor-suppressing proteins more than chemotherapy alone.

Cancer & TumorsNo Effects Found684 citations

Continuous exposure to 1.7 GHz LTE electromagnetic fields increases intracellular reactive oxygen species to decrease human cell proliferation and induce senescence

Choi J, Min K, Jeon S, Kim N, Pack JK, Song K · 2020

This study examined the effects of continuous 1.7 GHz LTE radiofrequency electromagnetic field (RF-EMF) exposure on various human cell types including stem cells, cancer cells, and normal fibroblasts. The researchers found that 72-hour RF-EMF exposure at 1 and 2 SAR decreased cell proliferation across all tested cells, increased intracellular reactive oxygen species (ROS), and induced cell senescence without causing DNA breaks or apoptosis, with effects mediated through ROS-dependent mechanisms.

Cancer & Tumors684 citations

Radio frequency-induced superoxide accumulation affected the growth and viability of Saccharomyces cerevisiae

Li Q, Tian M, Teng J, Gao P, Tang BQ, Wu H · 2020

This study examined how radio frequency electromagnetic fields (2.6-5 MHz) at low power density affected growth and viability of Saccharomyces cerevisiae yeast cells. Results showed time-dependent effects, with initial growth promotion (43.5% increase at 30 hours) that reversed to growth inhibition (20.7% reduction at 89 hours), alongside superoxide accumulation in exposed cells that may explain the reduced viability at longer exposure times.

Isoflurane preconditioning ameliorates electromagnetic pulse-induced neural damage by shifting microglia polarization toward anti-inflammatory phenotype via upregulation of SOCS1

Zhang X, Lv M, Zhu X, Tian L, Li J, Shao Y, Gao C, Sun X · 2019

This study investigated how isoflurane preconditioning protects against neural damage caused by electromagnetic pulse exposure in rats. The researchers found that isoflurane preconditioning reduces neuroinflammation by shifting microglial cells from a pro-inflammatory to an anti-inflammatory state through upregulation of SOCS1, thereby reducing neuronal death.

Department of Health and Human Services. 384 pp

NTP 2018. NTP Technical Report on the Toxicology and Carcinogenesis Studies in Hsd:Sprague Dawley SD Rats exposed to Whole-body Radio Frequency Radiation at a Frequency (900 MHz) and Modulations (GSM and CDMA) used by Cell Phones. National Toxicology Program et al. · 2018

This National Toxicology Program technical report documents toxicology and carcinogenesis studies in Sprague Dawley rats exposed to whole-body radio frequency radiation at 900 MHz using GSM and CDMA modulations typical of cell phone frequencies. The study systematically evaluated potential health effects from radiofrequency exposure under controlled laboratory conditions.

Cancer & Tumors177 citations

(2018) Thermal and non-thermal health effects of low intensity non-ionizing radiation: An international perspective

Belpomme et al · 2018

This comprehensive review by international researchers examined the health effects of low-intensity electromagnetic fields from sources like cell phones and wireless devices. The authors found strong evidence linking long-term mobile phone use to increased brain cancer risk, reproductive harm, and neurological problems including a condition called electro-hypersensitivity. They concluded that current safety standards fail to protect public health, especially for children who are more vulnerable to EMF damage.

Cancer & Tumors3,965 citations

Association between parental occupational exposure to extremely low frequency magnetic fields and childhood nervous system tumors risk: A meta-analysis

Su L, Zhao C, Jin Y, Lei Y, Lu L, Chen G · 2018

This 2018 meta-analysis examined the association between parental occupational exposure to extremely low frequency (ELF) magnetic fields and the risk of childhood nervous system tumors. The study synthesized evidence from multiple research studies to evaluate whether occupational ELF magnetic field exposure in parents is associated with increased tumor risk in their children.

Cancer & Tumors2,343 citations

Effects of prolonged exposure to moderate static magnetic field and its synergistic effects with alkaline pH on Enterococcus faecalis

Fan W, Huang Z, Fan B · 2018

This study examined how prolonged exposure to moderate static magnetic field (SMF) at 170 mT, alone and combined with alkaline pH, affects the bacterium Enterococcus faecalis. The results showed that SMF exposure inhibited cell proliferation after 120 hours, and the combination of SMF with alkaline pH demonstrated synergistic antimicrobial effects while simultaneously upregulating stress response and virulence genes in the surviving bacteria.

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