Radiations and Cell Division
Arthur C. Giese · 1947
Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.
Showing 706 studies in DNA & Genetic Damage
Arthur C. Giese · 1947
Pirovano, A. · 1934
Unknown authors
Researchers exposed marrow cells from three leukemia patients in remission to 2450 MHz continuous-wave microwaves at four power levels for 15 minutes. Sham exposures used the same chamber without microwave power. Colony formation was significantly reduced at 500 and 1000 mW/cm2 but not at lower power levels.
Kenneth T. S. Yao, Mayme M. Jiles
Researchers grew cells derived from the bone marrow and retinal choroid of the rat kangaroo (Rotrurus tridactylus) and exposed them to 2450 MHz microwave radiation for 5 to 20 minutes at distances of 10, 25, or 50 cm. Short exposure times at the longer distances resulted in cell growth greater than that of unirradiated controls. Longer exposure times at shorter distances impaired cell proliferation. Chromosome damage appeared in cells exposed at 10 cm for at least 10 minutes, and the percentage of damaged cells increased with longer exposure. When cells were sensitized with 5-bromodeoxyuridine, chromosome damage tripled.
Unknown authors
Researchers exposed Salmonella typhimurium to 2.45 GHz amplitude-modulated microwave radiation at an average specific absorption rate of approximately 2.5 mW/g in a waveguide inside a 37°C incubator. Stationary-phase and log-phase bacteria were exposed for three hours, and stationary-phase bacteria were also exposed for 24 hours. No effect on viability or mutation frequency was seen after three-hour exposure, but one of five strains exposed for 24 hours showed reduced viability and increased mutation frequency compared with a 37°C control, though not compared with a 39°C control. Reconstruction experiments found the vial temperature inside the waveguide was about 1.5°C higher than the incubator temperature, which could explain the observed changes.
Unknown authors
Researchers conducted preliminary testing of magnetic field mutagenicity using bacterial systems with field strengths ranging from 0.1 to 1.1 Tesla. Salmonella strain TA98, which mutates by frameshift, did not show an increase in mutation frequency. Initial tests with E. coli, B. subtilis, and Photobacterium fisheri also produced suggestive data of increased mutation frequencies.