6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 2,816 studies in Whole Body / General

Pulsed electromagnetic fields regulate metabolic reprogramming and mitochondrial fission in endothelial cells for angiogenesis

Unknown authors · 2024

The study used tube formation and CCK-8 assays, a Seahorse assay, mitochondrial membrane potential assays, mitochondrial imaging, reactive oxygen species assays, and real-time PCR to examine the effects of PEMFs on human umbilical vein endothelial cells. Tube formation was significantly greater in the PEMF group than in controls. PEMFs shifted HUVEC energy metabolism from oxidative phosphorylation to aerobic glycolysis and caused mitochondria to become shorter and more granular.

Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury

Rai V et al. · 2024

In a pilot study, researchers used a Yucatan miniswine model of traumatic brain injury with and without electromagnetic field stimulation to investigate differential gene expression between injured and non-injured cortex tissues. They found several differentially expressed genes including INSC, TTR, CFAP126, SEMA3F, CALB1, CDH19, and SERPINE1. These genes are associated with immune cell infiltration, myelination, reactive oxygen species regulation, thyroid hormone transportation, cell proliferation, and cell migration. There was a time-dependent effect of EMF stimulation on gene and protein expression. The findings support the beneficial effect of EMF stimulation in the repair process following traumatic brain injury.

Low frequency-pulsed electromagnetic fields promote osteogenic differentiation of bone marrow-derived mesenchymal stem cells by regulating connexin 43 expression

Lu Z-J, Gu H-Y, Li Z-Q, Lin F-X · 2024

Researchers investigated how low-frequency pulsed electromagnetic fields affect osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells and the role of connexin 43. BMSCs were isolated and cultured using adherent whole-bone marrow cultures, exposed to LPEMF at 80 Hz for 1 h, which yielded the highest proliferation and notably increased osteogenic ability as measured by ALP activity, osteogenic marker genes, and Alizarin Red S staining. Connexin 43 expression increased during osteogenic differentiation after LPEMF exposure, and inhibiting Cx43 partially reversed the enhanced differentiation.

Protective effects of pulsed electromagnetic field therapy attenuates autophagy and apoptosis in osteoporotic osteoarthritis model rats by activating PPARγ

Liu J et al. · 2024

Researchers randomly assigned rats to control, osteoporotic osteoarthritis, and PEMF groups with six rats each. The PEMF group received pulsed electromagnetic field exposure at 3.82 mT and 8 Hz for 40 minutes per day, five days per week, for 12 weeks. PEMF retarded cartilage degeneration and bone loss, decreased MMP-13 expression, and increased bone mineral density. PEMF also inhibited serum inflammatory cytokines and caspase-3 and caspase-8 expression, upregulated PPARγ, and decreased Beclin-1, P62, and LC3B expression.

The impact of radiofrequency exposure on Aedes aegypti (Diptera: Culicidae) development

Unknown authors · 2024

Researchers exposed 30 Aedes aegypti eggs to radiofrequency radiation at baseline, 900 MHz, and 18 GHz, with each frequency tested in triplicate. They assessed hatching responses, development times, larval numbers, and pupation periods until adult emergence. The 900 MHz group showed the highest hatching rate at 79 ± 10.54% and the lowest adult emergence rate at 33 ± 2.77%, with a significant difference between groups (p = 0.03).

The neuroprotective effects of baobab and black seed on the rat hippocampus exposed to a 900-MHz electromagnetic field

Mohamed H, Deniz OG, Kaplan S · 2024

Fifty-six male, 12-week-old Wistar albino rats were divided into eight groups of seven animals each. The control, baobab, and black seed groups received no EMF exposure, while a sham group was placed in the exposure system without field, and the EMF+AD, EMF+BS, EMF+AD+BS and EMF groups received a 900-MHz EMF for one hour daily over 28 days. Stereological analysis found no statistically significant difference in pyramidal neuron numbers between the EMF group and the control or sham groups. Histopathological analysis showed that 900-MHz EMF produced adverse changes in neuronal structures. Qualitative examinations suggested that a combination of baobab and black seed exerts a protective effect against such EMF side-effects.

Maternal linalool treatment protects against radiofrequency wave-induced deteriorations in adolescent rats: A behavioral and electrophysiological study

Azimzadeh M, Noorbakhshnia M · 2024

Pregnant rats were divided into four groups (control, wave, wave+linalool, linalool), received linalool at 25 mg/kg by gavage for 21 days, and were irradiated from day 0 to day 21 of pregnancy. Offspring were tested on postnatal days 50 and 60 and showed anxiety-like behavior in the EPM test, impaired learning and memory in the Morris water maze and shuttle box, and reduced fEPSP amplitude and slope at the hippocampal CA3-CA1 synapse. Hippocampal iron, copper, manganese, and copper/zinc ratio were increased while zinc was decreased in exposed offspring, and linalool administration reversed the increases and normalized most trace elements except zinc.

The endocannabinoid system is involved in the anxiety-like behavior induced by dual- frequency 2.65/0.8 GHz electromagnetic radiation in mice

Xue T et al. · 2024

The study compared emotional effects of single-frequency and dual-frequency electromagnetic radiation in mice while exploring molecular mechanisms. Single-frequency EMR at 2.65 or 0.8 GHz did not induce anxiety-like behavior, whereas dual-frequency EMR at 2.65/0.8 GHz significantly caused anxiety-like behavior. Administering the cannabinoid receptor agonist Win55-212-2 significantly alleviated the anxiety-like behavior, and the antagonist AM251 blocked this effect.

Whole Body / GeneralNo Effects Found

Mobile phone specific radiation disturbs cytokinesis and causes cell death but not acute chromosomal damage in buccal cells: Results of a controlled human intervention study

Unknown authors · 2024

Researchers conducted a controlled human intervention trial exposing participants to a UMTS signal via headsets at two specific absorption rates for two hours daily over five consecutive days. Buccal cells were collected from both cheeks before exposure and three weeks later to score micronuclei and other nuclear anomalies. The study found no increase in micronuclei or nuclear buds, but observed a significant increase in binucleated cells and karyolitic cells. No such effects were seen on the less exposed side of the head. The authors concluded that the exposure did not cause acute chromosomal damage but did disturb the cell cycle and cause cytotoxicity.

Exposure to Radiofrequency Electromagnetic Fields Enhances Melanin Synthesis by Activating the P53 Signaling Pathway in Mel-Ab Melanocytes

Kim JH et al. · 2024

Researchers exposed Mel-Ab melanocytes to 1760 MHz RF-EMF at a specific absorption rate of 4.0 W/kg for 4 hours per day over 4 days. Exposure significantly increased melanin production, indicating enhanced skin pigmentation. Phosphorylation of CREB and expression of MITF were significantly increased after RF-EMF exposure. Tyrosinase expression increased significantly but its activity did not change. Expression of p53 and MC1R also increased significantly.

Effects of 4G Long-Term Evolution Electromagnetic Fields on Thyroid Hormone Dysfunction and Behavioral Changes in Adolescent Male Mice

Kim H-Y et al. · 2024

Four-week-old male mice were exposed to LTE EMF at a whole-body average SAR of 4 W/kg or to lead at 300 ppm in drinking water for four weeks. The mice underwent open field, marble burying, and nest building tests. LTE exposure increased T3 levels, while lead exposure elevated T3 and T4 and decreased ACTH levels. LTE EMF did not alter gene expression in the thyroid or pituitary glands but significantly reduced hypothalamic Dio2 and Dio3 expression.

Changes in honey bee nutrition after exposure to radiofrequency electromagnetic field

Unknown authors · 2024

Researchers exposed 2-day-old Carniolan worker honey bees to radiofrequency fields of 12 V/m, 28 V/m, and 61 V/m for 0.25, 1, and 3 hours. Hemolymph was collected from 40 bees per group immediately after exposure to measure total proteins, glucose, triglycerides, and TAS activity. The 12 V/m and 28 V/m exposure groups showed statistically significant differences in total proteins, TAS, and triglycerides compared to controls in most cases. The researchers concluded that radiofrequency electromagnetic fields disturb honey bee nutrition and the changes may have long-term effects.

Biological effects of electromagnetic fields on insects: a systematic review and meta-analysis

Thill A, Cammaerts MC, Balmori A · 2023

This systematic review summarizes the results of studies investigating the toxicity of electromagnetic fields in insects. The review focuses on detrimental effects from technological infrastructure, particularly power lines and cellular networks. Biological effects of non-thermal EMF on insects are clearly proven in the laboratory but only partly in the field. The authors state that extrapolating from laboratory results warrants increasing the threat level of environmental EMF impact on insects.

Davis D. Wireless technologies, non-ionizing electromagnetic fields and children: Identifying and reducing health risks. Curr Probl Pediatr Adolesc Health Care. 2023. doi: 10.1016/j.cppeds.2023.101374

Unknown authors · 2023

The review examines experimental, epidemiological, and clinical evidence on biological impacts of wireless technology on children. The review reports that more than half of toddlers regularly use screens contrary to pediatric guidelines, and that early device use is linked to speech delays, technoference, and addiction-like behaviors. The authors recommend an ALARA approach for microwave radiation and an independently funded research program on long-term physical and psychological impacts.

The European Union assessments of radiofrequency radiation health risks – another hard nut to crack (Review)

Nyberg et al · 2023

A 2017 article described the WHO as unwilling to acknowledge health effects from wireless phones. The WHO was characterized as 'A Hard Nut to Crack'. The EU is following the WHO's approach and has not acknowledged any risks from radiofrequency radiation despite increasing evidence. Seven appeals by scientists and medical doctors have requested a halt to 5G rollout since September 2017. The appeals have been ignored.

(2023) An Exposimetric Electromagnetic Comparison of Mobile Phone Emissions: 5G versus 4G Signals Analyses by Means of Statistics and Convolutional Neural Networks Classification

Miclaus et al · 2023

Researchers used signal and spectrum analyzers with statistical functions to compare exposimetric descriptors of emissions from file download, file upload, video streaming, and video calls on 4G and 5G networks. The method measured highest and lowest electric field strengths at 10 cm from the phone and highlighted prevalent power distribution functions. A convolutional neural network classified the emissions with very high accuracy, enabling traceability of human exposure dynamics.

Regulation of LTP at rat hippocampal Schaffer-CA1 in vitro by musical rhythmic magnetic fields generated by red-pink (soothing) music tracks

Jin Z, Dong L, Tian L, Zhou M, Zheng Y · 2023

Researchers generated seven time-varying magnetic fields with musical rhythm from three music tracks (Turkish March, Moonlight Sonata, Funeral March) and four sinusoidal frequencies (3500 Hz, 2500 Hz, 1500 Hz, 500 Hz) at a mean intensity of about 2 mT, and recorded LTP at Schaffer-CA1 synapses using a multi-electrode array. The rhythmic magnetic fields from Turkish March and Moonlight Sonata significantly increased fEPSP amplitude, with the effect growing at higher frequencies, whereas the Funeral March field did not significantly enhance LTP. Sinusoidal magnetic fields at 3500 Hz and 2500 Hz enhanced fEPSP amplitude more than the musical rhythmic fields, while fields at 1500 Hz and 500 Hz inhibited fEPSP amplitude.

Effect of prenatal stress and extremely low-frequency electromagnetic fields on anxiety-like behavior in female rats: With an emphasis on prefrontal cortex and hippocampus

Hosseini E, Kianifard D · 2023

The study used 24 female rats divided into four groups: control, prenatal stress, ELF-EMF exposure, and combined stress plus ELF-EMF. Anxiety-like behavior was assessed with elevated plus-maze and open field tests. All treatment groups showed increased anxiety-like behavior, with the combined stress and ELF-EMF group showing the most serious anxiety. Expression of caspase-3 was upregulated and BDNF and GAP-43 were downregulated in the prefrontal cortex, dentate gyrus, and CA1 across treatment groups. Histomorphological analysis revealed extensive neurodegenerative changes in the hippocampus and prefrontal cortex.

Investigating the molecular mechanisms of delirium-like neuropsychiatric disorder induced by electromagnetic pulse based on bioinformatics analysis

Zhang X-J et al. · 2023

EMP exposure induced anxiety, cognitive decline, and short-term memory impairment. The study identified 41 differentially expressed lncRNAs and 266 differentially expressed mRNAs between EMP and sham groups. Sixty-one co-expression relationships between 18 lncRNAs and 56 mRNAs were linked to synapse and metabolic pathways. A DEL-miRNA-DEM network was constructed with 51 DEL-miRNA pairs and 290 miRNA-mRNA pairs. LncRNA AABR07042999.1 and mRNAs Tph2, Slc6a4, Dbh, and Th were upregulated, and serotonin, dopamine, and norepinephrine levels increased in the prefrontal cortex and hippocampus.

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