3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,014 studies (Rodent Studies)

Cancer & TumorsNo Effects Found

Mobile phone base station radiation does not affect neoplastic transformation in BALB/3T3 cells.

Hirose H et al. · 2008

Researchers exposed mouse cells to radiofrequency radiation from mobile phone base stations for six weeks to see if it would cause cancerous changes. Even at high exposure levels (800 mW/kg), the radiation did not increase the rate of cell transformation into cancer cells. This suggests that base station radiation at these levels doesn't directly promote tumor formation in laboratory conditions.

Brain & Nervous SystemNo Effects Found

Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation.

Grafström G et al. · 2008

Swedish researchers exposed rats to GSM-900 cell phone radiation once weekly for over a year at power levels similar to what humans experience during phone calls. When they examined the rats' brains afterward, they found no signs of damage including blood-brain barrier leakage, cell death, or aging-related changes. This suggests that intermittent cell phone radiation exposure at typical usage levels may not cause detectable brain tissue damage.

Cellular EffectsNo Effects Found

Whole-body exposure of radiation emitted from 900 MHz mobile phones does not seem to affect the levels of anti-apoptotic bcl-2 protein.

Yilmaz F, Dasdag S, Akdag MZ, Kilinc N · 2008

Turkish researchers exposed rats to radiation from 900 MHz cell phones for 20 minutes daily over one month to see if it affected bcl-2, a protein that helps prevent cell death in the brain and reproductive organs. They found no changes in bcl-2 levels in either brain or testicular tissue. This suggests that at least for this specific protein marker, short-term cell phone radiation exposure may not trigger cellular death pathways in these organs.

DNA & Genetic DamageNo Effects Found

No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal

Paparini A et al. · 2008

Researchers exposed mice to cell phone radiation at 1800 MHz (the frequency used by GSM phones) for one hour to see if it changed gene activity in their brains. Using advanced genetic analysis techniques, they found no significant changes in how genes were expressed in the brain tissue. This suggests that short-term exposure to this type of cell phone radiation at the levels tested does not trigger major changes in brain cell function at the genetic level.

Brain & Nervous SystemNo Effects Found

Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain

Kim TH et al. · 2008

Researchers exposed mice to cell phone radiation at 849 MHz and 1763 MHz frequencies for up to 12 months, delivering radiation directly to their heads at levels much higher than typical phone use. They found no evidence of brain cell death, abnormal cell growth, or other cellular changes in the exposed animals compared to unexposed controls.

Brain & Nervous SystemNo Effects Found

Histopathological examinations of rat brains after long-term exposure to GSM-900 mobile phone radiation.

Grafström G et al. · 2008

Swedish researchers exposed rats to GSM-900 mobile phone radiation for 2 hours weekly over 55 weeks at very low power levels (0.6 and 60 milliwatts per kilogram). When they examined the rats' brains afterward, they found no signs of damage including blood-brain barrier leakage, cell death, or aging-related changes. This contradicts some earlier studies from the same research group that found brain effects at similar exposure levels.

Brain & Nervous SystemNo Effects Found

Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats

Ammari M et al. · 2008

French researchers exposed rats to 900 MHz cell phone radiation (the same frequency used by GSM phones) for either 8 or 24 weeks, then tested their spatial memory using a maze. The rats showed no memory problems compared to unexposed rats, even at radiation levels up to four times higher than current safety limits. This suggests that chronic cell phone radiation exposure may not impair spatial learning and memory functions in the brain.

Upregulation of specific mRNA levels in rat brain after cell phone exposure.

Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HS. · 2008

Researchers exposed rats to cell phone radiation for 6 hours daily over 18 weeks and found significant increases in brain proteins associated with injury and cellular stress. The study measured mRNA (genetic instructions for protein production) levels of four key proteins involved in brain cell damage and repair. These findings suggest that chronic cell phone exposure may cause cumulative brain injuries that could eventually lead to neurological problems.

Chronic non-thermal exposure of modulated 2450 MHz microwave radiation alters thyroid hormones and behavior of male rats.

Sinha RK · 2008

Researchers exposed male rats to chronic microwave radiation at 2450 MHz (the same frequency used by microwave ovens and WiFi) and measured changes in thyroid hormones and behavior. The exposed rats became hyperactive and aggressive, while also showing significant disruptions in thyroid hormone levels - specifically decreased T3 and increased T4. These behavioral and hormonal changes were statistically correlated, suggesting that microwave exposure can disrupt the endocrine system in ways that directly affect behavior.

Effects of electromagnetic radiation use on oxidant/antioxidant status and dna turn-over enzyme activities in erythrocytes and heart, kidney, liver, and ovary tissues from rats: possible protective role of Vitamin C.

Devrim E et al. · 2008

Researchers exposed female rats to 900 MHz electromagnetic radiation (the frequency used by cell phones) for 4 weeks and measured markers of cellular damage in their blood and organs. They found significant oxidative stress - essentially cellular damage from harmful molecules called free radicals - in the blood cells and kidneys of exposed rats. When some rats were given vitamin C along with the radiation exposure, it provided partial protection against this cellular damage.

Long-term exposure to extremely low-frequency magnetic fields impairs spatial recognition memory in mice.

Fu Y, Wang C, Wang J, Lei Y, Ma Y. · 2008

Chinese researchers exposed mice to extremely low-frequency magnetic fields (the same type emitted by power lines and household appliances) for either 7 or 25 days, then tested their spatial memory using a maze. While short-term exposure had no effect, mice exposed to 50 Hz fields for 25 days showed impaired ability to recognize new areas in the maze. This suggests that chronic exposure to power-frequency magnetic fields may interfere with spatial memory and navigation abilities.

Effects of Electromagnetic Radiation Use on Oxidant/Antioxidant Status and DNA Turn-over Enzyme Activities in Erythrocytes and Heart, Kidney, Liver, and Ovary Tissues From Rats: Possible Protective Role of Vitamin C

Devrim E et al. · 2008

Researchers exposed female rats to 900 MHz electromagnetic radiation (the frequency used by cell phones) for four weeks and measured oxidative stress markers in blood cells and organs. The EMF exposure increased oxidative stress and tissue damage in red blood cells and kidneys, while vitamin C provided some protection against these effects. This suggests that cell phone radiation may cause cellular damage through oxidative stress pathways.

Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice.

Hashish AH, El-Missiry MA, Abdelkader HI, Abou-Saleh RH. · 2008

Researchers exposed mice to magnetic fields and 50 Hz electromagnetic fields (the type from power lines) for 30 days to study health effects. The exposed mice lost weight and showed signs of liver stress, including increased oxidative damage (cellular damage from unstable molecules) and changes in blood chemistry. The study suggests that prolonged exposure to these common electromagnetic fields may disrupt the body's ability to protect itself from cellular damage.

Melatonin reduces oxidative stress induced by chronic exposure of microwave radiation from mobile phones in rat brain.

Sokolovic D et al. · 2008

Researchers exposed rats to mobile phone radiation at levels similar to human exposure for up to 60 days and found significant brain damage from oxidative stress - essentially, cellular damage from harmful molecules. When rats were given melatonin (a natural hormone), it partially protected their brains from this radiation damage. This suggests that mobile phone radiation can harm brain cells through oxidative stress, and that melatonin might offer some protection.

Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex.

Nittby H et al. · 2008

Researchers exposed rats to cell phone radiation at 1,800 MHz for 6 hours and found significant changes in brain gene activity. The genetic alterations affected genes controlling cell membranes and cellular communication in the cortex and hippocampus, the same brain regions where previous studies documented blood-brain barrier damage.

Effect of chronic intermittent exposure to AM radiofrequency field on responses to various types of noxious stimuli in growing rats.

Mathur R · 2008

Researchers exposed growing rats to AM radio frequency fields (similar to some communication systems) for 2 hours daily over 45 days and tested their pain responses. The exposed rats showed altered pain processing - they became more emotionally reactive to short-term pain but less sensitive to long-term pain. This suggests that chronic RF exposure during development can rewire how the nervous system processes different types of pain signals.

Apoptosis is Induced by Radiofrequency Fields through the Caspase-Independent Mitochondrial Pathway in Cortical Neurons.

Joubert V, Bourthoumieu S, Leveque P, Yardin C. · 2008

French researchers exposed rat brain cells to cell phone-level radiofrequency radiation (900 MHz at 2 W/kg SAR) for 24 hours and found it triggered programmed cell death through a specific cellular pathway. The brain cells died at rates significantly higher than control groups, even when accounting for the slight temperature increase from the radiation. This suggests that RF radiation can damage neurons through mechanisms beyond just heating effects.

Study on potential effects of "902-MHz GSM-type Wireless Communication Signals" on DMBA-induced mammary tumours in Sprague-Dawley rats.

Hruby R, Neubauer G, Kuster N, Frauscher M · 2008

Researchers exposed rats to 902 MHz GSM-type wireless signals (similar to cell phone radiation) for 4 hours daily over 6 months after giving them a chemical known to cause breast cancer. The RF-exposed rats showed statistically significant increases in palpable tissue masses and more malignant tumors compared to sham-exposed controls, though the researchers concluded these differences were likely incidental due to high variability in the cancer model used.

Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones.

Eberhardt JL, Persson BR, Brun AE, Salford LG, Malmgren LO. · 2008

Swedish researchers exposed rats to cell phone radiation at 900 MHz for 2 hours and examined their brains 14 and 28 days later. They found that the radiation compromised the blood-brain barrier (the protective shield around the brain) and caused nerve cell damage. The blood-brain barrier leaked proteins into brain tissue within 14 days, while actual nerve cell death appeared after 28 days.

Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats.

Ammari M et al. · 2008

French researchers exposed rats to 900-MHz cell phone radiation for up to 24 weeks to test whether it would impair their spatial memory and navigation abilities. The rats showed no memory deficits even when exposed to radiation levels 3-12 times higher than typical cell phone use. This suggests that chronic exposure to GSM cell phone signals may not directly damage the brain's memory systems.

Exposure to GSM 900 MHz electromagnetic fields affects cerebral cytochrome c oxidase activity.

Ammari M, Lecomte A, Sakly M, Abdelmelek H, de-Seze R. · 2008

French researchers exposed rats to cell phone radiation and measured brain enzyme activity. High-intensity exposure (6 W/kg) for 15 minutes daily reduced brain activity in memory and decision-making regions after one week. Lower exposures showed no effects, suggesting intensity matters for brain function.

Effect of a chronic GSM 900MHz exposure on glia in the rat brain.

Ammari M et al. · 2008

French researchers exposed rats to cell phone radiation (900 MHz) for 24 weeks and found that high-level exposure caused persistent brain inflammation. The study measured GFAP, a protein that increases when brain support cells called astrocytes become activated in response to injury or stress. This suggests that chronic cell phone radiation exposure may trigger ongoing inflammatory responses in brain tissue.

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