3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

Filter Studies

Clear all filters

Showing 1,014 studies (Rodent Studies)

Cancer & TumorsNo Effects Found

GSM and DCS wireless communication signals: combined chronic toxicity/carcinogenicity study in the Wistar Rat.

Smith P, Kuster N, Ebert S, Chevalier HJ · 2007

Researchers exposed 1,170 rats to cell phone radiation (GSM and DCS signals) for 2 hours daily, 5 days a week for up to 2 years to test whether this exposure causes cancer. They found no increase in tumors or cancer rates compared to unexposed control rats, even at the highest radiation levels tested. This large, long-term study suggests that chronic exposure to these specific wireless signals at the tested levels does not increase cancer risk in rats.

Cancer & TumorsNo Effects Found

Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats.

Shirai T et al. · 2007

Researchers exposed young rats to cell phone-like radiation (1.95 GHz W-CDMA signals) for 2 years to see if it would promote brain tumor development in animals already given a cancer-causing chemical. The study found no significant increase in brain tumors from the radiation exposure at levels of 0.67 and 2.0 W/kg SAR. This suggests that chronic exposure to this type of cell phone radiation does not accelerate brain tumor formation in this animal model.

Cancer & TumorsNo Effects Found

Effects of exposure of newborn patched1 heterozygous mice to GSM, 900 MHz.

Saran A et al. · 2007

Researchers exposed newborn mice genetically engineered to be highly susceptible to tumors to cell phone radiation (900 MHz GSM) for 30 minutes twice daily over 5 days. The exposed mice showed no increased cancer risk, no shortened lifespan, and no acceleration of tumor development compared to unexposed mice. This study suggests that brief early-life exposure to cell phone radiation at typical levels may not promote cancer development, even in genetically vulnerable subjects.

Brain & Nervous SystemNo Effects Found

Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba(2+) currents through voltage-gated calcium channels in rat cortical neurons.

Platano D et al. · 2007

Italian researchers exposed rat brain cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) for short periods to see if it affected calcium channels, which are crucial for nerve cell communication. They found no changes in how calcium moved through these channels, even at radiation levels of 2 W/kg. This suggests that brief cell phone-level exposures may not immediately disrupt this particular aspect of brain cell function.

Cancer & TumorsNo Effects Found

Carcinogenicity Study of 217 Hz Pulsed 900 MHz electromagnetic fields in pim1 transgenic mice.

Oberto G et al. · 2007

Researchers exposed genetically modified mice to pulsed 900 MHz radiofrequency radiation (similar to cell phone signals) for 18 months to test whether it could cause cancer. Despite using exposure levels up to three times higher than a previous study that found increased lymphomas, this larger study found no increase in tumors or cancer at any of the tested exposure levels. This contradicts earlier research suggesting cell phone radiation might promote cancer development.

Brain & Nervous SystemNo Effects Found

Effects of acute exposure to a 1439 MHz electromagnetic field on the microcirculatory parameters in rat brain.

Masuda H et al. · 2007

Researchers exposed rats to cell phone frequency radiation (1,439 MHz) for 10 minutes at three different power levels to see if it affected blood flow and the blood-brain barrier in their brains. They found no changes in any of the brain circulation measurements, including blood vessel size, blood flow speed, and whether the protective blood-brain barrier became more permeable. This suggests that short-term exposure to this type of radiofrequency radiation did not disrupt normal brain blood circulation.

Brain & Nervous SystemNo Effects Found

Effects of subchronic exposure to a 1439 MHz electromagnetic field on the microcirculatory parameters in rat brain.

Masuda H et al. · 2007

Researchers exposed rats' heads to cell phone-level radiation (1439 MHz) for one hour daily over four weeks to study effects on brain blood vessels. They found no changes in blood-brain barrier function, immune cell behavior, or blood flow in the brain. This suggests that this level of radiofrequency exposure may not disrupt the brain's delicate blood vessel system.

DNA & Genetic DamageNo Effects Found

Micronucleus frequency in erythrocytes of mice after long-term exposure to radiofrequency radiation.

Juutilainen J, Heikkinen P, Soikkeli H, Mäki-Paakkanen J. · 2007

Finnish researchers exposed mice to cell phone radiation for over a year to test whether it damages DNA by looking for micronuclei (broken chromosome fragments) in blood cells. They found no DNA damage from radiofrequency exposure at levels similar to what humans experience from mobile phones. This was true across different phone technologies (analog and digital), exposure durations (52-78 weeks), and mouse strains.

Brain & Nervous SystemNo Effects Found

No apoptosis is induced in rat cortical neurons exposed to GSM phone fields.

Joubert V, Leveque P, Cueille M, Bourthoumieu S, Yardin C. · 2007

French researchers exposed rat brain neurons to cell phone radiation (900 MHz GSM) for 24 hours at levels similar to phone use (0.25 W/kg SAR) to see if it would cause cell death (apoptosis). Using three different testing methods, they found no increase in neuron death compared to unexposed control cells. This suggests that short-term cell phone radiation exposure may not directly kill brain cells under these laboratory conditions.

Brain & Nervous SystemNo Effects Found

Acute exposure to low-level CW and GSM-modulated 900 MHz radiofrequency does not affect Ba 2+ currents through voltage-gated calcium channels in rat cortical neurons.

Platano D et al. · 2007

Italian researchers exposed rat brain cells to 900 MHz radiofrequency radiation (the same frequency used by GSM cell phones) to see if it affected calcium channels, which are crucial for brain cell communication. After exposing the cells to radiation at 2 W/kg for short periods, they found no changes in how calcium moved through these channels. This suggests that brief exposure to cell phone-level radiation may not immediately disrupt this particular aspect of brain cell function.

Brain & Nervous SystemNo Effects Found

No apoptosis is induced in rat cortical neurons exposed to GSM phone fields.

Joubert V, Leveque P, Cueille M, Bourthoumieu S, Yardin C. · 2007

French researchers exposed rat brain neurons to cell phone radiation (900 MHz GSM) for 24 hours at levels similar to phone use, then tested whether the radiation caused brain cells to die through a process called apoptosis. Using three different measurement methods, they found no increase in cell death compared to unexposed neurons. This suggests that brief cell phone radiation exposure may not directly damage brain cells in the way some scientists have theorized.

Reproductive Health181 citations

Effects of cellular phone emissions on sperm motility in rats.

Yan JG, Agresti M, Bruce T, Yan YH, Granlund A, Matloub HS. · 2007

Researchers exposed male rats to cellular phone emissions for 6 hours daily over 18 weeks and found significantly higher rates of sperm cell death compared to unexposed rats. The exposed rats also showed abnormal clumping of sperm cells that wasn't present in the control group. This suggests that keeping cell phones close to reproductive organs could harm male fertility.

Effects of electromagnetic field produced by mobile phones on the oxidant and antioxidant status of rats.

Elhag MA, Nabil GM, Attia AM. · 2007

Researchers exposed rats to mobile phone radiation for either short daily sessions (15 minutes for 4 days) or a single acute dose, then measured their antioxidant levels. Both exposure patterns dramatically reduced essential antioxidants like vitamin C (down 47-60%), vitamin E (down 33-66%), and key protective enzymes. The single acute exposure caused more severe damage than the repeated shorter exposures, suggesting that even brief intense EMF exposure can overwhelm the body's natural defenses against cellular damage.

Effect of whole-body exposure to high-frequency electromagnetic field on the brain cortical and hippocampal activity in mouse experimental model.

Barcal J, Vozeh F. · 2007

Researchers measured brain activity in mice while exposing them to 900 MHz radiofrequency radiation (the same frequency used by cell phones). They found that this exposure caused measurable changes in brain wave patterns in both the cortex and hippocampus - key brain regions involved in thinking and memory. The changes were most pronounced in healthy mice, suggesting that cell phone-frequency radiation can directly alter normal brain function.

Oxidative Stress129 citations

Effects of mobile phones on oxidant/antioxidant balance in cornea and lens of rats.

Balci M, Devrim E, Durak I. · 2007

Researchers exposed rats to mobile phone radiation for 4 weeks and measured oxidative stress markers in their eye tissues (cornea and lens). The radiation significantly increased harmful oxidative stress in both tissues, while vitamin C supplementation prevented these effects. This suggests that mobile phone radiation can damage delicate eye tissues through oxidative stress, but antioxidants may offer protection.

Anticancer effects on leiomyosarcoma-bearing Wistar rats after electromagnetic radiation of resonant radiofrequencies.

Avdikos A et al. · 2007

Greek researchers exposed cancer cells to specific radiofrequencies (10-120 kHz) and found these treated cells formed tumors that grew more slowly and caused less death in rats. When rats with existing tumors were exposed to the same resonant frequencies for 5 hours daily, one-third of their tumors completely disappeared. This suggests certain electromagnetic frequencies might have therapeutic rather than harmful effects on cancer.

900 MHz radiofrequency-induced histopathologic changes and oxidative stress in rat endometrium: protection by vitamins E and C.

Guney M, Ozguner F, Oral B, Karahan N, Mungan T. · 2007

Researchers exposed female rats to 900 MHz radiofrequency radiation (similar to cell phone frequencies) for 30 minutes daily over 30 days and examined the effects on endometrial tissue (the lining of the uterus). The radiation caused significant oxidative damage and tissue inflammation in the endometrium, but these harmful effects were largely prevented when the rats were given vitamins E and C. This suggests that cell phone-frequency radiation may damage reproductive tissues through oxidative stress, but antioxidant protection could help mitigate these effects.

Effects of electromagnetic field produced by mobile phones on the oxidant and antioxidant status of rats

Elhag MA, Nabil GM, Attia AM. · 2007

Researchers exposed rats to mobile phone radiation using two different patterns. Both exposures significantly reduced protective antioxidants like vitamin C and vitamin E by up to 60%. Single intense exposures caused more antioxidant damage than repeated shorter exposures, suggesting exposure timing affects cellular protection.

Effect of whole-body exposure to high-frequency electromagnetic field on the brain cortical and hippocampal activity in mouse experimental model

Barcal J, Vozeh F · 2007

Researchers exposed mice to 900 MHz electromagnetic radiation (the same frequency used by cell phones) and directly measured brain activity in two key regions: the cortex and hippocampus. They found that this radiation altered normal brain wave patterns, shifting cortical activity to lower frequencies while increasing higher frequencies in the hippocampus. These changes occurred even though the mice received lower radiation doses than humans typically get when using cell phones.

Formation of reactive oxygen species in L929 cells after exposure to 900 MHz RF radiation with and without Co-exposure to 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone.

Zeni O et al. · 2007

Researchers exposed mouse cells to 900 MHz cell phone radiation for up to 30 minutes to test whether it creates harmful reactive oxygen species that damage cells. The study found no increase in these damaging molecules from RF exposure alone, suggesting this frequency may not cause oxidative cellular stress.

Carcinogenicity study of GSM and DCS wireless communication signals in B6C3F1 mice.

Tillmann T et al. · 2007

Researchers exposed 1,170 mice to cell phone radiation from GSM and DCS wireless signals for 2 hours daily over 2 years to test whether this exposure causes cancer. The study found no increase in cancer rates at any of the three radiation levels tested, including the highest level of 4.0 W/kg. Interestingly, male mice actually showed fewer liver tumors at higher radiation doses, though overall tumor rates remained within normal ranges for laboratory mice.

Electromagnetic pulses induce fluctuations in blood pressure in rats.

Li BF, Guo GZ, Ren DQ, Zhang RB. · 2007

Researchers exposed rats to electromagnetic pulses (intense bursts of electromagnetic energy) and measured their blood pressure for four weeks afterward. The study found that these pulses caused immediate spikes in blood pressure, followed by drops below normal levels that lasted up to a month. This suggests that even brief electromagnetic exposures can trigger lasting changes in cardiovascular function.

Effect of an acute 900MHz GSM exposure on glia in the rat brain: A time-dependent study.

Brillaud E, Piotrowski A, de Seze R. · 2007

French researchers exposed rats to cell phone radiation (900MHz GSM signal) for just 15 minutes and then examined their brains over the following 10 days. They found significant increases in glial cell activity (brain cells that support and protect neurons) in multiple brain regions, peaking 2-3 days after exposure. This glial response indicates the brain was reacting to the radiation exposure as if responding to injury or stress.

Effects of static magnetic fields on the voltage-gated potassium channel currents in trigeminal root ganglion neurons.

Shen JF, Chao YL, Du L. · 2007

Researchers exposed rat nerve cells from the trigeminal ganglion (which controls facial sensation) to static magnetic fields at 125 millitesla and measured how this affected potassium channels that help control nerve cell activity. They found that the magnetic field altered how these channels turned off (inactivated), potentially disrupting normal nerve function. This suggests that moderate-strength magnetic fields can physically deform cell membranes and change how critical ion channels operate.

Browse by Health Effect