Jajte J, Zmyślony M, Rajkowska E. · 2003
Researchers examined whether melatonin and vitamin E could protect rat blood lymphocytes from lipid peroxidation caused by iron ions and a 7 mT static magnetic field in vitro. Simultaneous exposure to the 7 mT static magnetic field and iron ions produced a significant increase in lipid peroxidation end-products compared with control samples and those exposed to the field alone. When cells were pre-treated with melatonin or vitamin E before that same exposure, lipid peroxidation was significantly reduced, and melatonin was less effective than vitamin E under these conditions.
Mashevich M et al. · 2003
Researchers examined whether in vitro exposure of human peripheral blood lymphocytes to continuous 830 MHz electromagnetic fields causes losses and gains of chromosomes, a condition called aneuploidy. Cells were irradiated at SAR levels ranging from 1.6 to 8.8 W/kg for 72 hours. A linear increase in chromosome 17 aneuploidy was observed as a function of the SAR value, which the researchers described as a genotoxic effect. Control experiments conducted without any RF radiation across a temperature range of 34.5 to 38.5 °C showed that elevated temperature was not associated with the increased aneuploidy or the changes in centromeric DNA replication seen after RF exposure.
Unknown authors · 2002
Researchers analyzed expression of immediate early response genes c-fos, c-jun, and c-myc in human glioblastoma T98G cells exposed to 1-500 μT 60 Hz elliptically polarized magnetic fields for up to 3 h. No statistically significant differences were found in gene expression ratios at both transcriptional and translational levels for c-fos and c-jun at 30 min and for c-myc at 180 min after serum stimulation. Similarly, exposure to linearly or circularly polarized 500 μTr fields produced no significant change in expression ratios at both transcriptional and post-transcriptional levels.
Unknown authors · 2002
Researchers exposed Ku80-deficient xrs5 cells and Ku80-proficient CHO-K1 cells to ELF electromagnetic fields. ELF field exposure alone did not affect cell survival, cell cycle distribution, or protein expression in either cell line. In xrs5 cells, ELF exposure after irradiation inhibited G1 cell cycle arrest, increased bcl-2 expression, and decreased p53, phospho-p53, caspase-3, and p21 protein levels. ELF exposure for 10 hours after irradiation reduced X-ray-induced apoptosis in xrs5 cells from about 1.7% to 0.7%, but this effect was not observed in CHO-K1 cells.
Unknown authors · 2002
Unknown authors · 2002
Researchers exposed differentiating IMR-32 neuroblastoma cells to 60 Hz magnetic fields at 50, 100, and 200 microT for 4 hours. They measured APP695 mRNA levels using northern hybridization with Digoxygenin-labeled probes. The results provided no support for any relationship between APP695 gene transcription and either differentiation age or magnetic field exposure.
Unknown authors · 2002
Researchers exposed 10-day-old mice to a 1 mT, 60 Hz magnetic field for 2 hours and measured DNA damage at multiple time points using the alkaline comet assay. They also measured apoptosis in the external granule cell layer of the cerebellum at 0 and 24 hours using the TUNEL assay. Increased DNA damage was detected by tail ratio at 2 hours but not by the other comet assay parameters, and no increase in apoptosis was observed compared to sham-exposed mice.
Unknown authors · 2002
EMF exposure increased sulfate incorporation, glycosaminoglycan content, chondrocyte number at day 8, cartilage volumetric density, and immunostaining for antibodies 3B3 and 5D4. DNA content and thymidine incorporation did not differ between groups, indicating no increase in cell proliferation. Proteoglycan and glycosaminoglycan molecular sizes and composition were unchanged, showing accelerated synthesis of normal cartilage molecules. Expression of proteoglycan and type II collagen mRNA increased, along with greater immunoreactivity for 3B3 and 504, suggesting faster chondrocyte differentiation and phenotypic maturation.
Miyakoshi, J., Yoshida, M., Tarusawa, Y., et al. · 2002
Unknown authors · 2002
Unknown authors · 2002
A cross-sectional questionnaire survey was conducted in 1997 among 15,000 men and women aged 19 to 80 in Stockholm County with a 73% response rate. One and a half percent of respondents reported hypersensitivity to electric or magnetic fields. Prevalence was highest among women and in the 60- to 69-year age group. The hypersensitive group reported all symptoms, allergies, and other hypersensitivities, as well as being disturbed by various home factors, to a significantly greater extent than other respondents. No specific symptom profile distinguished the hypersensitive group from other respondents.
Unknown authors · 2002
Hypersensitivity to EMFs has been reported for nearly 20 years but the literature remains very limited. Nearly all literature concerns a dermatological syndrome with subjective symptoms such as itching and burning that appear after working with video display units and decrease during absence from work. Case-control studies and limited double-blind trials have not found a clear relationship between this syndrome and EMF exposure. A general syndrome with more general symptoms has been rarely described and appears to have a worse prognosis. The symptoms are mainly neurasthenic and nonspecific, overlapping with multiple chemical sensitivity and chronic fatigue, yet no valid etiological studies have been published for this general syndrome.
Unknown authors · 2002
Researchers reported the results of a telephone survey among a sample of 2,072 Californians. Being allergic or very sensitive to electrical devices was reported by 68 subjects, giving an adjusted prevalence of 3.2%. The strongest predictor of reporting hypersensitivity was a doctor-diagnosed environmental illness or multiple chemical sensitivity. Risk perception from hair dryers was most associated with self-reporting, but risk perception alone did not explain the characteristics.
Unknown authors · 2002
Researchers sent a questionnaire to 350 patients registered with electrical sensitivity at a Swedish hospital from 1980 to 1998, achieving a 73% response rate. The study included 50 respondents with hypersensitivity to electricity (38% men, 62% women) and 200 with VDT-related skin symptoms (21.5% men, 78.5% women). Patients with hypersensitivity to electricity were more often not gainfully employed (38% vs 17%) and their medical prognosis did not improve over time, unlike the VDT group.
Unknown authors · 2002
Unknown authors · 2002
Researchers conducted a nested case-control study with 177 cases and 550 controls to assess the relation between retrospective magnetic field measures and clinical miscarriage among Kaiser Permanente members in northern California. They evaluated wire codes, area measures, and three personal meter metrics including rate-of-change, maximum level, and time-weighted average. For personal metrics at 30 weeks, adjusted odds ratios for the highest quartile were 3.1 for rate-of-change, 2.3 for maximum value, and 1.7 for time-weighted average. A prospective substudy of 219 participants found exposure measurements at 12 weeks were poorly correlated with those at 30 weeks, yet miscarriage risk results were consistent with the nested study.
Unknown authors · 2002
Unknown authors · 2002
Researchers conducted case-referent studies of Alzheimer's disease, amyotrophic lateral sclerosis, and Parkinson's disease using death records of males in Colorado from 1987 to 1996. Three exposure assessment methods were used: electrical versus nonelectrical occupations, a three-tiered job-title and industry grouping, and a job-exposure matrix with magnetic-field means. Amyotrophic lateral sclerosis was associated with electrical occupations but not with magnetic-field exposure from the job-exposure matrix. No consistent associations with magnetic fields were observed for Alzheimer's disease.
Unknown authors · 2002
Female Sprague Dawley rats were MF or sham exposed for 2 weeks at a flux density of 100 microTesla. Proliferation of epithelial cells in the mammary tissue and adjacent skin was examined by in vivo labeling with bromodeoxyuridine (BrdUrd) and in situ labeling of Ki-67 protein by the antibody MIB-5. MF exposure significantly enhanced BrdUrd and Ki-67 labeling in the mammary epithelium, indicating a marked increase in cell proliferation. Melatonin levels in pineal or mammary glands were not affected by MF exposure. Topical application of 12-O-tetradecanoylphorbol-13-acetate increased BrdUrd and Ki-67 labeling in skin epithelial cells, particularly hair follicles, but not in mammary tissue.
Unknown authors · 2002
Unknown authors · 2002
The paper estimates the annual number of excess illness cases that might occur near high-voltage powerlines in the UK. Within 150m of powerlines, magnetic field exposures above 0.1 microT are postulated to result in 9000 excess cases of depression in adults and 60 cases of suicide. Within 400m of powerlines, this may result annually in 200-400 excess cases of lung cancer, 2000-3000 cases of other illnesses associated with air population and 2-6 cases of childhood leukaemia. Seventeen cases of non-melanoma skin cancer might occur by exposure directly under powerlines.
Unknown authors · 2002
Human diploid fibroblasts were exposed to continuous or intermittent ELF-EMF at 50 Hz, sinusoidal, for 24 hours at 1000 microT. The alkaline and neutral comet assays were used to evaluate DNA single-strand and double-strand breaks. Intermittent fields reproducibly resulted in a significant increase of DNA strand break levels, mainly DSBs, compared to non-exposed controls. The highest DNA strand break levels occurred with 5 minutes field-on and 10 minutes field-off intermittence.
Unknown authors · 2002
Researchers measured magnetic fields and two sources of contact current in 36 homes in Pittsfield, MA. The first source, VP–W, is the voltage due to current in the grounding wire, and the second, VW–E, is the voltage between the water pipe and earth.
Unknown authors · 2002
Unknown authors · 2002
However, research reports indicate that living cells may respond to power-frequency fields well below the thermal noise limits. The study proposes that published thermal arguments may not fully account for all membrane force fields of thermal origin, and that a full accounting could show smaller net thermal noise fields in the power-frequency range.
