6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

Filter Studies

Clear all filters

Showing 1,318 studies matching "radiofrequency"

(2022) Estimation of RF and ELF dose by anatomical location in the brain from wireless phones in the MOBI-Kids study

Calderón et al · 2022

Researchers created an algorithm for the MOBI-Kids study to estimate cumulative specific energy from RF fields and cumulative induced current density from ELF fields in the brain of subjects aged 10 to 24 years. The algorithm considered age, tumour location, phone models, usage patterns, and communication system prevalence over time. Median RF and ELF doses were substantially higher for GSM than 3G systems and varied considerably by brain location. Agreement between RF dose estimates and phone use variables was moderate to null depending on communication system, while agreement for ELF dose was higher but also system-dependent. Duration and number of calls may not be adequate proxies for dose as communication systems become more complex over time.

Acute and Chronic Exposure to 900 MHz Radio Frequency Radiation Activates p38/JNK-mediated MAPK Pathway in Rat Testis

Unknown authors · 2022

Rats were exposed to 900 MHz RFR at 2 h/day, 5 days/week for 1 week (acute) or 10 weeks (chronic). The study measured histopathology, PCNA, Bcl-xL, cleaved caspase-3, p-JNK, p-p38, and TUNEL in testis tissue. No histopathological differences or PCNA changes were observed between sham and RFR groups in either period. Cleaved caspase-3 and Bcl-xL showed period-dependent alterations, TUNEL-positive cells increased significantly only after acute exposure, and both p-p38 and p-JNK protein expressions increased significantly in both acute and chronic RFR groups.

Mobile Phone Radiation Deflects Brain Energy Homeostasis and Prompts Human Food Ingestion

Unknown authors · 2022

In a single-blind, sham-controlled, randomized crossover study, 15 normal-weight young men were exposed to 25 minutes of RF-EMFs from two mobile phone types or sham radiation under fasting conditions. Spontaneous food intake was measured with an ad libitum buffet test and cerebral energy homeostasis was monitored using phosphorus-31 magnetic resonance spectroscopy. Exposure increased overall caloric intake by 22–27% compared to sham, mainly due to higher carbohydrate consumption, and cerebral energy content increased as shown by higher ATP and phosphocreatine ratios to inorganic phosphate.

Whole Body / GeneralNo Effects Found

Human resting-state EEG and radiofrequency GSM mobile phone exposure: The impact of the individual alpha frequency

Int J Radiat Biol 98(5):986-995, 2022 · 2022

Twenty-one healthy volunteers participated in a double-blind, randomized, counterbalanced crossover study with eyes-open and eyes-closed resting-state EEG recordings. The exposure system was a sham or real GSM 900 MHz mobile phone pulse modulated at 217 Hz with a mean power of 250 mW and a maximum specific absorption rate of 0.70 W/kg. EEG power spectral density was computed for the alpha band in a fixed 8-12 Hz range and for each individual's alpha frequency range. A trend toward decreased or increased alpha power during exposure was observed for eyes-closed and eyes-open conditions respectively, but did not reach statistical significance. The findings did not provide evidence for different sensitivity to RF-EMF related to individual alpha frequency variability.

Changes in the histopathology and in the proteins related to the MAPK pathway in the brains of rats exposed to pre and postnatal radiofrequency radiation over four generations

Tan B, Tan FC, Yalcin B, Dasdag S, Yegin K, Yay AH · 2022

The study created four groups (sham, irradiated female, irradiated male, and irradiated male and female) with one male and three females each. The irradiated groups were whole-body exposed to 2450 MHz continuous wave radiofrequency radiation for 12 hours per day across four generations. The researchers examined fetal brain development, histopathological changes in female rats, and hippocampal MAPK protein levels in male rats. In exposed groups, hemorrhagic areas, irregular cellular localization, and vascular structures were observed in the brains of fetal and adult female rats across all generations. In adult male rats, phosphorylated ERK, tau, JNK, and p38 were significantly increased in the brain across all generations.

Effect of 2400 MHz mobile phone radiation exposure on the behavior and hippocampus morphology in Swiss mouse model

Hasan I, Jahan MR, Islam MN, Islam MR · 2022

Researchers exposed Swiss albino male mice to 2400 MHz RF-EMR for 40 or 60 minutes daily over 60 days. Exposed mice showed a significant increase in anxiety-like behavior on the elevated plus-maze compared to controls. Stereological analysis revealed a significant decrease in pyramidal and granule neurons in the hippocampus of exposed mice. Histological examination showed degenerative alterations including black and dark blue cytoplasmic cells with shrunken morphology in the hippocampus.

Changes in the excitability of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields

Unknown authors · 2022

The study investigated changes in neuronal activity and synaptic transmission after a 60-minute exposure to 3.0 GHz RF-EMF at a low dose (SAR < 1 W/kg). RF-EMF exposure decreased the amplitude of action potentials, depolarized resting membrane potential, and increased neuronal excitability and synaptic transmission in cultured primary hippocampal neurons.

Estimated all-day and evening whole-brain radiofrequency electromagnetic fields doses, and sleep in preadolescents

Unknown authors · 2022

Researchers estimated all-day and evening whole-brain radiofrequency electromagnetic field doses from phone calls, screen activities, and far-field sources in preadolescents aged 9 to 12 years from two birth cohorts. Sleep disturbances were assessed via a maternal questionnaire and objective sleep measures were recorded using wrist accelerometers and sleep diaries for seven consecutive days. All-day whole-brain RF-EMF doses were not associated with self-reported sleep disturbances or objective sleep measures, while high evening whole-brain RF-EMF dose from phone calls was associated with 11.9 minutes less total sleep time.

3.5-GHz radiofrequency electromagnetic radiation promotes the development of Drosophila melanogaster

Unknown authors · 2022

Researchers exposed fruit flies to simulated 3.5 GHz radiofrequency electromagnetic radiation at intensities of 0.1, 1, and 10 W/m². Exposure increased early pupation and eclosion rates and shortened the mean development time. In larvae, heat shock protein and immune gene expression rose, oxidative stress enzymes increased, and microbial diversity fell while Acetobacter and Lactobacillus genera increased.

2.4 GHz Electromagnetic Field Influences the Response of the Circadian Oscillator in the Colorectal Cancer Cell Line DLD1 to miR-34a- Mediated Regulation

Unknown authors · 2022

Researchers exposed miR-34a-transfected DLD1 colorectal cancer cells to 2.4 GHz RF-EMF for 24 hours and evaluated effects using real-time PCR, scratch assay, and MTS test. Administration of miR-34a decreased expression of per2, bmal1, sirtuin1, and survivin and inhibited proliferation and migration of DLD1 cells. RF-EMF exposure increased cry1 mRNA expression, weakened miR-34a's inhibition of per2, abolished its inhibition of survivin, and eliminated miR-34a's effects on proliferation and migration. The authors concluded that RF-EMF strongly influenced miR-34a-mediated regulation of the peripheral circadian oscillator in DLD1 cells.

Cancer & Tumors100 citations

Molecular Mechanism of Malignant Transformation of Balb/c-3T3 Cells Induced by Long-Term Exposure to 1800 MHz Radiofrequency Electromagnetic Radiation (RF-EMR)

Ding Z, Xiang X, Li J, Wu S · 2022

Researchers exposed Balb/c-3T3 cells to 1800 MHz RF continuous wave for 40 and 60 days, 4 hours per day, and compared them with sham-exposed cells. Exposed cells showed increased proliferation and migration, malignant transformation with visible foci and clone formation, and formed tumors when transplanted into SCID mice.

Effects of Acute Exposure to 3500 MHz (5G) Radiofrequency Electromagnetic Radiation on Anxiety- Like Behavior and the Auditory Cortex in Guinea Pigs

Yang H, Zhang Y, Wu X, Gan P, Luo X, Zhong S, Zuo W · 2022

Researchers exposed forty male guinea pigs to 3500 MHz RF-EMR at SARs of 0, 2, 4, or 10 W/kg for 72 hours. They measured malondialdehyde levels, antioxidant enzyme activities, anxiety-like behavior, hearing thresholds, cell ultrastructure, and apoptosis in the auditory cortex. Exposure increased MDA levels and decreased catalase, superoxide dismutase, and glutathione peroxidase activities in the auditory cortex. Ultrastructural changes included swollen mitochondria and layered myelin sheaths, and apoptosis markers such as cytochrome-c relocalization and caspase activation were observed. Hearing thresholds and basic behavior indexes did not change significantly.

Effects of continuous prenatal and postnatal global system for mobile communications electromagnetic waves (GSM-EMW) exposure on the oxidative stress biomarkers in female rat liver

Unknown authors · 2022

Researchers continuously exposed pregnant Sprague-Dawley rats and their offspring to 900 MHz GSM-modulated RF-EMR for 24 hours per day and assessed liver oxidative stress at postnatal days 1, 9, and 21. Exposure significantly raised MDA levels at PND9 and PND21, lowered catalase activity at all ages, reduced catalase amount and mRNA at PND1 and PND9, and decreased GPx activity at PND21. CytoSOD levels increased at PND9 and 21 while mitoSOD levels decreased at PND21, and both GPx level and mitoSOD activity were elevated at all ages. SOD1 mRNA expression rose at PND1 but fell at PND9 and 21, whereas GPx1 expression was consistently reduced in the exposed group.

Exposure to 1.8 GHz radiofrequency field modulates ROS in human HEK293 cells as a function of signal amplitude

Unknown authors · 2022

Researchers exposed human HEK293 cultured cells to a 1.8 GHz carrier frequency at amplitudes typical of household telecommunications. ROS concentrations increased significantly after 15 minutes of exposure and were localized to both nuclear and cytosolic compartments. qPCR analysis revealed altered gene expression of anti-oxidative enzymes SOD, GPX, and CAT, and oxidative enzyme Nox-2. Multiple genes responsive to static magnetic fields were also regulated by RF, suggesting common response mechanisms. Many RF effects showed evidence of hormesis with biphasic dose-response curves and blind spots at certain amplitudes.

Investigation of oxidative damage, antioxidant balance, DNA repair genes, and apoptosis due to radiofrequency-induced adaptive response in mice

Unknown authors · 2022

The study used 24 adult male Swiss-Albino mice divided into Four groups of 6. The radiofrequency and adaptive response groups were exposed to a 900 MHz GSM signal at 0.339 W/kg for 4 h/day over 7 days. After the final exposure, bleomycin was injected intraperitoneally at 37.5 mg/kg and the mice were sacrificed 30 minutes later. Oxidative damage and antioxidant mechanisms were examined in blood, DNA-repair gene expression was measured in liver, and apoptosis was assessed in liver using the TUNEL method. The adaptive response group showed increased ROS and p53 and OGG-1 expression, decreased SOD, CAT and TAC levels, and reduced apoptosis.

Evaluation of Cell Migration and Cytokines Expression Changes under the Radiofrequency Electromagnetic Field on Wound Healing In Vitro Model

Costantini E et al. · 2022

The study aimed to explore the therapeutic potential of different RF-EMF exposure setups to drive faster healing by evaluating keratinocyte migration, cytokines, and MMP expression. RF-EMF treatment promoted keratinocytes' migration and regulated the expression of genes involved in healing, such as MMPs, tissue inhibitors of metalloproteinases, and pro/anti-inflammatory cytokines, to improve WH.

B. Blake Levitt, Henry C. Lai, Albert M. Manville. Effects of non-ionizing electromagnetic fields on flora and fauna, Part 3. Exposure standards, public policy, laws, and future directions. Rev Environ Health. 2021 Sep 27. doi: 10.1515/reveh-2021-0083

Unknown authors · 2021

The review examines government standards adopted for human exposures for their applicability to wildlife. It states that existing environmental laws such as the National Environmental Policy Act and the Migratory Bird Treaty Act should be strengthened and enforced, and new laws written for increasing EMF exposures. Radiofrequency radiation exposure standards warrant more stringent controls given 5G signaling characteristics, and no current standards take wildlife into consideration. Numerous studies indicate low-level EMF exposures have adverse effects on orientation, migration, reproduction, and other behaviors, and cyto- and geno-toxic effects have long been observed.

Lost opportunities for cancer prevention: historical evidence on early warnings with emphasis on radiofrequency radiation

Hardell & Carlberg · 2021

The paper discusses historical lessons from early warnings on cancer risks and lost prevention opportunities. It states that radiofrequency radiation has a cancer-causing effect and that decades of studies show increased human cancer risk. Based on three case-control studies of wireless phone use, the authors present a preventable fraction for brain tumors and note an increase in undefined brain tumors in Sweden, especially among ages 20–39, which they suggest may be linked to high wireless phone use among young people.

(2021) Effects of mobile phone usage on sperm quality – No time-dependent relationship on usage: A systematic review and updated meta-analysis

Kim et al · 2021

The authors conducted a systematic review and updated meta-analysis following PRISMA guidelines. They evaluated 18 studies comprising 4280 samples. The outcome measures were sperm motility, viability, and concentration. Exposure to mobile phones was associated with reduced sperm motility, viability, and concentration. The decrease in sperm quality after RF-EMW exposure was not significant even when mobile phone usage increased.

Browse by Health Effect