Of 274 studies examining immune system, 77% found measurable biological effects from EMF exposure.
Research found effects on immune system at exposures as low as:
When 106 out of 129 studies (82.2%) document immune system effects from electromagnetic field exposure, we're looking at one of the most consistently demonstrated biological impacts of EMF. The science demonstrates that your body's natural defense system responds to wireless radiation in ways that can compromise your ability to fight infections, heal from injuries, and maintain optimal health.
While we don't yet have as many studies specifically examining EMF effects on immune function as we do for other biological systems, the evidence that does exist points to concerning patterns.
Importantly, many effects occur at exposure levels below those causing significant body temperature increases, with some studies showing responses at specific absorption rates as low as 0.14 W/kg.
Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org
Showing 274 studies
Trosic I, Matausicpisl M, Radalj Z, Prlic I, · 1999
Researchers exposed rats to microwave radiation at 2450 MHz for two hours daily over 30 days. The exposed rats showed decreased white blood cells and increased red blood cells compared to controls, indicating the radiation affected their immune and blood systems.
Novoselova, EG, Fesenko, EE, Makar, VR, Sadovnikov, VB · 1999
Russian researchers exposed mice to very low-level microwave radiation (similar to what cell towers emit) for 5 hours and found it significantly boosted immune system activity. The microwaves increased production of tumor necrosis factor (TNF), a key immune signaling molecule, in immune cells called macrophages and T-cells. This immune activation lasted for at least 3 days after exposure and was enhanced when mice were given antioxidant nutrients.
E.G Novoselova, E.E Fesenko, V.R Makar, V.B Sadovnikov · 1999
Researchers exposed mice to extremely low-power microwave radiation (8.15-18 GHz) for 5 hours and found it actually stimulated their immune systems, increasing production of immune signaling molecules and enhancing T cell activity. The immune boost was further enhanced when mice were given antioxidant nutrients like vitamin E and beta-carotene. This suggests that very low-level microwave exposure might trigger beneficial immune responses rather than suppress immunity.
Fesenko EE et al. · 1999
Russian researchers exposed mice to extremely low-power microwave radiation (8.15-18 GHz at 1 microW/cm²) for 24-72 hours and found their natural killer cells became 130-150% more active. Natural killer cells are immune system defenders that destroy cancer cells and virus-infected cells. The immune boost lasted 24 hours after exposure ended, but shorter exposures of 3-5 hours showed no effect.
Fesenko EE, Makar VR, Novoselova EG, Sadovnikov VB. · 1999
Researchers exposed mice to extremely low-level microwave radiation (8.15-18 GHz at just 1 microW/cm²) and found it significantly boosted production of TNF (tumor necrosis factor), a key immune system protein. Short-term exposure for 5 hours to 3 days enhanced immune cell activity, but chronic exposure for 7 days actually suppressed it. This demonstrates that even ultra-weak microwave radiation can measurably alter immune system function in living organisms.
Fesenko, EE, Makar, VR, Novoselova, EG, Sadovnikov, VB, · 1999
Russian researchers exposed mice to low-level microwave radiation and found it significantly altered immune system function. Short exposures boosted immune cell activity, while longer exposure suppressed it. These effects persisted for days after radiation ended, showing even weak microwaves can disrupt normal immunity.
Khadir R, Morgan JL, Murray JJ. · 1999
Scientists exposed human immune cells to 60 Hz magnetic fields at levels 440 times higher than household exposure. The fields amplified inflammatory responses when cells encountered other triggers, increasing harmful free radical production by 26.5%. This suggests power line frequencies may make immune systems overreact.
Dmoch A, Moszczynski P · 1998
Polish researchers studied immune system function in workers exposed to microwave radiation from TV transmission and satellite communication equipment (6-12 GHz frequencies). They found several changes in immune cell populations and antibody levels, including increased immunoglobulins (infection-fighting proteins) and altered ratios of different white blood cell types. However, the authors concluded these changes had no clinical significance, meaning they didn't appear to cause actual health problems.
Obukhan KI · 1998
Researchers exposed rats to microwave radiation at frequencies of 2375, 2450, and 3000 MHz and examined the effects on their blood-forming organs including bone marrow, spleen, and thymus. They found structural and functional changes in various types of blood cells that were dependent on radiation intensity, with bone marrow cell development and reproduction showing the most significant disruption. Even at low radiation intensities, the study detected increased numbers of immature blast cells and abnormal cell division patterns.
Novoselova ET, Fesenko EE. · 1998
Russian researchers exposed mice to extremely weak microwave radiation (8.15-18 GHz) at power levels 1,000 times lower than cell phones. The exposure significantly increased production of tumor necrosis factor, a key immune protein, suggesting even very low-level microwaves can alter immune function.
Nakamura et al. · 1998
Researchers exposed pregnant rats to microwave radiation at 2.45 GHz for 90 minutes and found it suppressed natural killer cells, which fight infections and cancer. This immune suppression occurred through the body's opioid system, showing microwave exposure can weaken immunity during pregnancy when protection is most critical.
Novoselova ET, Fesenko EE. · 1998
Russian researchers exposed mice to extremely weak microwave radiation (8.15-18 GHz at 1 microW/cm²) and found it significantly increased production of tumor necrosis factor in immune cells called macrophages. Tumor necrosis factor is a key protein that triggers inflammation and immune responses in the body. This suggests that even very low-power microwave radiation can alter immune system function.
Phillips et al. · 1998
Researchers exposed immune system cells to radiofrequency radiation from cell phone signals at extremely low power levels for 2 to 21 hours. They found that very low exposures actually reduced DNA damage, while slightly higher exposures increased DNA breaks in the cellular genetic material. This suggests that even minimal RF radiation can alter DNA integrity in immune cells, though the effects varied depending on the specific exposure level.
Phillips et al. · 1998
Researchers exposed immune cells to cell phone radiation at different power levels and measured DNA damage. They found that very low levels of radiation actually reduced DNA damage, while slightly higher levels increased it. This suggests that cell phone radiation can affect DNA in ways that depend on the specific exposure level.
Vijayalaxmi, Mohan, N, Meltz, ML, Wittler, MA, · 1997
Researchers exposed human blood cells to microwave radiation at 2450 MHz (the same frequency used in microwave ovens and WiFi) for 90 minutes to see if it would damage DNA or affect cell growth. They found no genetic damage, chromosome breaks, or changes in how fast the cells multiplied compared to unexposed cells. This suggests that short-term exposure to this type of radiation at these power levels may not immediately harm human blood cells.
Safronova VG et al. · 1997
Russian researchers exposed mouse immune cells (neutrophils) to 41.95 GHz millimeter waves at 150 microW/cm2 for 20 minutes to test effects on the cells' ability to produce reactive oxygen species - their primary defense mechanism. The millimeter waves reduced the cells' immune response by up to 60% when calcium levels were high, but only when calcium could enter the cells from outside. This suggests that millimeter wave radiation can interfere with normal immune cell function by disrupting calcium signaling pathways.
Antonopoulos A, Eisenbrandt H, Obe G, · 1997
Researchers exposed human immune cells (lymphocytes) to electromagnetic fields at frequencies used by cell phones and other wireless devices (380, 900, and 1800 MHz) to see if the radiation would damage the cells' DNA or disrupt their normal growth cycle. The study found no measurable differences between cells exposed to EMF and unexposed control cells. This suggests that these specific frequencies, under the conditions tested, did not cause detectable genetic damage or cellular disruption in immune cells.
Dolk H et al. · 1997
British researchers investigated cancer rates around a major TV and radio transmitter in Sutton Coldfield, England, studying 13 years of cancer registry data within a 10-kilometer radius. They found an 83% increased risk of adult leukemia within 2 kilometers of the transmitter, with cancer risk declining significantly as distance from the transmitter increased. This pattern remained consistent across different time periods and appeared independent of an initially reported cancer cluster.
Repacholi et al. · 1997
Scientists exposed genetically cancer-prone mice to 900 MHz radiofrequency fields (similar to cell phone signals) for 30 minutes twice daily for up to 18 months. The exposed mice developed lymphoma (a type of cancer) at 2.4 times the rate of unexposed mice. This suggests that cell phone-type radiation may accelerate cancer development in those already genetically susceptible.
Nakamura et al. · 1997
Scientists exposed pregnant and non-pregnant rats to microwave radiation at 2450 MHz for 90 minutes. Pregnant rats showed weakened immune systems and hormonal changes that didn't occur in non-pregnant rats, suggesting pregnancy increases vulnerability to wireless radiation from everyday devices.
Nakamura H, Seto T, Nagase H, Yoshida M, Dan S, Ogino K. · 1997
Japanese researchers exposed pregnant and non-pregnant rats to microwave radiation at 2450 MHz (the same frequency used by microwave ovens and WiFi) for 90 minutes at 10 mW/cm². They found that pregnant rats showed significant immune system suppression, with reduced natural killer cell activity in the spleen, while non-pregnant rats showed no immune changes. The study reveals that pregnancy makes organisms more vulnerable to microwave radiation effects.
Donnellan M, McKenzie DR, French PW. · 1997
Researchers exposed immune cells called mast cells to cell phone radiation at 835 MHz for 20 minutes, three times daily for a week. They found that starting on day four, the cells began growing faster, changed shape, and became more reactive to chemical triggers. What's particularly concerning is that these changes persisted for at least a week after the radiation exposure ended, suggesting the effects may be long-lasting.
Gapeev AB, Lakushina VS, Chemeris NK, Fesenko EE · 1997
Russian researchers exposed mouse immune cells to extremely high frequency radiation (42 GHz) at low power for 20 minutes. Depending on how the radiation was pulsed, it either boosted or suppressed the cells' infection-fighting ability by 25%, showing weak electromagnetic fields can significantly alter immune function.
Donnellan M, McKenzie DR, French PW · 1997
Researchers exposed immune cells called mast cells to 835 MHz radiofrequency radiation (similar to cell phone frequencies) for 20 minutes three times daily over a week. The exposed cells showed increased DNA synthesis, altered cell shape, and enhanced release of inflammatory substances compared to unexposed cells. These cellular changes persisted for at least a week after the radiation exposure ended, suggesting the effects may trigger lasting biological responses.
Szmigielski, S · 1996
Polish researchers tracked cancer rates in 128,000 military personnel over 15 years, comparing those occupationally exposed to radiofrequency and microwave radiation with unexposed colleagues. They found the exposed group had more than double the overall cancer rate (119 vs 58 cases per 100,000 annually), with particularly striking increases in blood cancers like leukemia (up to 14 times higher) and brain tumors. This large-scale occupational study provides compelling evidence that RF/microwave exposure significantly increases cancer risk.
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