3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 3,138 peer-reviewed studies on electromagnetic field health effects from the BioInitiative Report database.

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Showing 1,644 studies in Brain & Nervous System

Long term and excessive use of 900 MHz radiofrequency radiation alter microRNA expression in brain.

Dasdag S et al. · 2015

Researchers exposed rats to cell phone radiation (900 MHz) for 3 hours daily over an entire year to study effects on microRNAs - tiny molecules that control gene activity in the brain. The radiation significantly decreased levels of one specific microRNA (miR-107) that helps regulate brain cell function. This finding suggests that long-term cell phone use may disrupt the brain's genetic control systems, potentially leading to neurological problems.

Cognitive Impairment and Neurogenotoxic Effects in Rats Exposed to Low-Intensity Microwave Radiation.

Deshmukh PS et al. · 2015

Researchers exposed rats to extremely low-intensity microwave radiation at cell phone frequencies (900, 1800, and 2450 MHz) for 180 days and found significant cognitive impairment and DNA damage in brain tissue. The exposure levels were thousands of times lower than current safety limits, yet still caused measurable harm including memory problems and genetic damage. This challenges the assumption that only high-intensity radiation poses health risks.

Neuritin reverses deficits in murine novel object associative recognition memory caused by exposure to extremely low-frequency (50 Hz) electromagnetic fields.

Zhao QR, Lu JM, Yao JJ, Zhang ZY, Ling C, Mei YA. · 2015

Researchers exposed mice to 50 Hz magnetic fields from power lines for 12 hours daily, finding it impaired memory recognition and damaged brain cells in the hippocampus. The damage was reversible with protective proteins, showing power-line frequencies can measurably affect brain function.

Exposure to 50 Hz magnetic field modulates GABAA currents in cerebellar granule neurons through an EP receptor-mediated PKC pathway.

Yang G, Ren Z, Mei YA. · 2015

Researchers exposed rat brain cells to power line frequency magnetic fields (50 Hz) and found they significantly boosted GABA receptor activity - the brain's main calming system. This change could potentially affect sleep, anxiety, and seizure control, showing how electromagnetic fields may influence brain function.

Effects of two different waveforms of ELF MFs on bioelectrical activity of antennal lobe neurons of Morimus funereus (Insecta, Coleoptera).

Todorović D, Prolić Z, Petković B, Kalauzi A. · 2015

Researchers exposed longhorn beetles to 50 Hz magnetic fields (the same frequency as power lines) and measured how their brain neurons responded. They found that square wave magnetic fields caused measurable changes in neural activity after 10-15 minutes of exposure, while sine wave fields did not. This demonstrates that even insects show biological responses to power-frequency magnetic fields, and that the waveform shape matters for biological effects.

Improvement of spatial memory disorder and hippocampal damage by exposure to electromagnetic fields in an Alzheimer's disease rat model.

Liu X et al. · 2015

Researchers exposed rats with artificially induced Alzheimer's disease symptoms to 50-Hz electromagnetic fields (the same frequency as household power lines) for 60 days. The EMF exposure actually improved the rats' memory and reduced brain damage associated with Alzheimer's disease. This suggests that certain types of electromagnetic field exposure might have protective effects on the brain, contrary to concerns about EMF causing neurological harm.

Effects of a 60 Hz Magnetic Field Exposure Up to 3000 μT on Human Brain Activation as Measured by Functional Magnetic Resonance Imaging.

Legros A, Modolo J, Brown S, Roberston J, Thomas AW. · 2015

Researchers scanned people's brains after one-hour exposure to 60 Hz magnetic fields from power lines. Brain scans showed altered activation patterns during tasks, even though performance stayed normal. This suggests magnetic field exposure can change how the brain functions, with effects lasting after exposure ends.

Exposure to 50 Hz electromagnetic field changes the efficiency of the scorpion alpha toxin.

Jankowska M et al. · 2015

Polish researchers exposed cockroaches to 50 Hz electromagnetic fields (the same frequency used in electrical power systems) and found it changed how their nervous systems responded to scorpion toxin. The EMF exposure altered nerve activity patterns and reduced the toxin's effectiveness, demonstrating that power frequency fields can modify how the nervous system functions at the cellular level.

Behavioural profile of Wistar rats with unilateral striatal lesion by quinolinic acid (animal model of Huntington disease) post-injection of apomorphine and exposure to static magnetic field.

Giorgetto C et al. · 2015

Researchers exposed rats with brain lesions (modeling Huntington's disease) to 3,200 Gauss static magnetic fields for seven days. Magnetic field exposure preserved brain neurons and improved movement compared to untreated rats, suggesting static magnetic fields may help brain healing in neurological conditions.

In vitro developmental neurotoxicity following chronic exposure to 50 Hz extremely low frequency electromagnetic fields (ELF-EMF) in primary rat cortical cultures.

de Groot MW, van Kleef RG, de Groot A, Westerink RH · 2015

Dutch scientists exposed developing rat brain cells to power line magnetic fields for seven days. They found minimal effects only at extremely high exposures (1000 microtesla) - about 10,000 times stronger than typical home levels. Normal residential exposures showed no significant developmental impacts.

Extremely low frequency magnetic field modulates the level of neurotransmitters.

Chung YH et al. · 2015

Researchers exposed laboratory rats to 60 Hz magnetic fields (the same frequency as household electrical systems) for 2 to 5 days and found significant changes in brain chemistry. The magnetic field exposure altered levels of key neurotransmitters including serotonin, dopamine, and norepinephrine across multiple brain regions. These chemical messengers control mood, movement, attention, and other critical brain functions.

Extremely low-frequency electromagnetic fields enhance the proliferation and differentiation of neural progenitor cells cultured from ischemic brains.

Cheng Y et al. · 2015

Researchers exposed brain stem cells (neural progenitor cells) from stroke-damaged brains to 50 Hz magnetic fields at 0.4 mT for 7 days. The magnetic field exposure significantly increased both cell multiplication and the development of these stem cells into neurons. This suggests that extremely low frequency electromagnetic fields might help brain recovery after stroke by promoting the growth of new brain cells.

Extremely Low Frequency Magnetic Field (ELF-MF) Exposure Sensitizes SH-SY5Y Cells to the Pro-Parkinson's Disease Toxin MPP.

Benassi B et al. · 2015

Researchers exposed human brain cells to 50 Hz magnetic fields (the same frequency as power lines) and found that while the fields didn't harm the cells directly, they made the cells much more vulnerable to a chemical toxin that causes Parkinson's disease-like damage. The magnetic field exposure disrupted the cells' natural antioxidant defenses, causing normally survivable toxin levels to trigger cell death through oxidative stress.

Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model.

Zuo WQ, Hu YJ, Yang Y, Zhao XY, Zhang YY, Kong W, Kong WJ. · 2015

Researchers exposed rat auditory nerve cells to mobile phone radiation at 2-4 W/kg levels, with and without mild inflammation. Radiation alone caused no damage, but significantly harmed pre-inflamed cells, suggesting EMF exposure may be more dangerous when your body is already fighting inflammation.

8-oxoG DNA Glycosylase-1 Inhibition Sensitizes Neuro-2a Cells to Oxidative DNA Base Damage Induced by 900 MHz Radiofrequency Electromagnetic Radiation.

Wang X et al. · 2015

Researchers exposed mouse brain cells to 900 MHz cell phone radiation for 24 hours and found it caused DNA damage through oxidative stress. The damage occurred at radiation levels as low as 1-2 watts per kilogram, which is within the range of typical cell phone use. When the cells' natural DNA repair mechanisms were disabled, even lower radiation levels caused genetic damage.

Static magnetic field exposure-induced oxidative response and caspase-independent apoptosis in rat liver: effect of selenium and vitamin E supplementations.

Ghodbane S, Ammari M, Lahbib A, Sakly M, Abdelmelek H. · 2015

Researchers exposed rats to strong static magnetic fields (128 mT) for one hour daily over five days and found significant liver damage, including increased oxidative stress and cell death through a process called apoptosis. The brain showed no similar damage, suggesting the liver is more vulnerable to magnetic field exposure. Even antioxidant supplements like selenium and vitamin E couldn't fully protect against the liver cell death.

Extremely low frequency magnetic field modulates the level of neurotransmitters.

Chung YH et al. · 2015

Researchers exposed rats to 60 Hz magnetic fields (the same frequency as household electricity) for 2-5 days and measured brain chemicals called neurotransmitters. They found significant changes in key brain chemicals including dopamine, serotonin, and norepinephrine across multiple brain regions. These neurotransmitters control mood, movement, and cognitive function, suggesting that magnetic field exposure can alter brain chemistry.

RKIP Regulates Neural Cell Apoptosis Induced by Exposure to Microwave Radiation Partly Through the MEK/ERK/CREB Pathway

Zuo H et al. · 2015

Researchers exposed nerve cells to microwave radiation at 2.856 GHz (similar to some wireless devices) for just 5 minutes and found it triggered cell death through a specific biological pathway. The radiation disrupted a protective protein called RKIP, which normally helps prevent nerve cells from dying, leading to increased cell death in the exposed samples. This suggests that even brief microwave exposure can interfere with the brain's natural protective mechanisms.

Effects of fetal microwave radiation exposure on offspring behavior in mice

Zhang Y, Li Z, Gao Y, Zhang C. · 2015

Researchers exposed pregnant mice to microwave radiation throughout pregnancy and tested their offspring's behavior. They found that prenatal microwave exposure increased anxiety-like behaviors in both male and female offspring, but only impaired learning and memory in males. This study provides the first evidence that microwave radiation can cause gender-specific developmental effects on the brain.

Microwave Exposure Impairs Synaptic Plasticity in the Rat Hippocampus and PC12 Cells through Over-activation of the NMDA Receptor Signaling Pathway.

Xiong L et al. · 2015

Researchers exposed rats and brain cells to microwave radiation at 30 mW/cm² and found significant damage to brain structures responsible for learning and memory. The exposure disrupted the delicate balance of brain chemicals and damaged the connections between brain cells (synapses). This suggests that microwave radiation can interfere with the brain's ability to form new memories and learn.

Activation of VEGF/Flk-1-ERK Pathway Induced Blood-Brain Barrier Injury After Microwave Exposure

Wang LF et al. · 2015

Researchers exposed lab-grown blood-brain barrier cells to microwave radiation at 50 mW/cm² for 5 minutes and found that this exposure damaged the protective barrier that normally prevents harmful substances from entering the brain. The microwaves activated specific cellular pathways that caused the tight connections between barrier cells to break down, making the barrier more permeable. This suggests that microwave radiation could potentially compromise the brain's natural protection system.

Does the Brain Detect 3G Mobile Phone Radiation Peaks? An Explorative In-Depth Analysis of an Experimental Study.

Roggeveen S, van Os J, Lousberg R · 2015

Dutch researchers measured brain activity in 31 women exposed to 3G phone radiation. Brain scans showed measurable electrical responses within milliseconds of exposure, even though participants couldn't consciously detect when phones were transmitting, proving brains unconsciously respond to mobile phone radiation.

EEG Changes Due to Experimentally Induced 3G Mobile Phone Radiation

Roggeveen S, van Os J, Viechtbauer W, Lousberg R · 2015

Researchers exposed 31 healthy women to 3G cell phone radiation for 15 minutes and measured brain activity using EEG (electroencephalogram, which records electrical activity in the brain). They found significant changes in multiple brain wave patterns when the phone was held to the ear, but not when placed on the chest. This demonstrates that cell phone radiation can directly alter brain activity in just 15 minutes of exposure.

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