6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

EMF Research Studies

Browse 6,486 peer-reviewed studies on electromagnetic field health effects from 4 research libraries.

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Showing 2,030 studies in Brain & Nervous System

GENDER DIFFERENCES IN EFFECTS OF PRENATAL AND POSTNATAL EXPOSURE TO ELECTROMAGNETIC FIELD AND PRENATAL ZINC ON BEHAVIOUR AND SYNAPTIC PROTEINS IN RATS

Unknown authors · 2022

Researchers exposed pregnant rats and their pups to EMF for 4 hours a day, 5 days a week, from the first day of pregnancy to postnatal day 42, with some groups also receiving zinc. EMF exposure significantly lowered SHANK3 and NLGN3 protein levels in the hippocampus and amygdala. Behavioural tests found no effect on social behaviour but increased anxiety and reduced activity and exploration. Zinc supplementation had a partially positive effect on female offspring but not on males. Zinc did not restore the reduced protein levels.

Effect of the prenatal electromagnetic field exposure on cochlear nucleus neurons and oligodendrocytes in rats

Unknown authors · 2022

Researchers randomly assigned pregnant Sprague-Dawley rats to a control group or a 900-MHz EMF exposure group, with the EMF group exposed daily until birth. Newborn rats were sacrificed by anesthesia on days 7, 10, 15, and 30. Structural damage in cochlear nuclear neurons and oligodendrocytes and increased caspase-3 activity were observed in the EMF groups compared to controls. However, no significant difference was found between groups in structural damage or caspase-3 activity across postnatal stages, and auditory brainstem response latencies did not differ. The authors concluded that prenatal 900-MHz EMF exposure has no harmful effects on ventral cochlear nucleus development.

Mobile Phone Radiation Deflects Brain Energy Homeostasis and Prompts Human Food Ingestion

Unknown authors · 2022

In a single-blind, sham-controlled, randomized crossover study, 15 normal-weight young men were exposed to 25 minutes of RF-EMFs from two mobile phone types or sham radiation under fasting conditions. Spontaneous food intake was measured with an ad libitum buffet test and cerebral energy homeostasis was monitored using phosphorus-31 magnetic resonance spectroscopy. Exposure increased overall caloric intake by 22–27% compared to sham, mainly due to higher carbohydrate consumption, and cerebral energy content increased as shown by higher ATP and phosphocreatine ratios to inorganic phosphate.

Changes in the histopathology and in the proteins related to the MAPK pathway in the brains of rats exposed to pre and postnatal radiofrequency radiation over four generations

Tan B, Tan FC, Yalcin B, Dasdag S, Yegin K, Yay AH · 2022

The study created four groups (sham, irradiated female, irradiated male, and irradiated male and female) with one male and three females each. The irradiated groups were whole-body exposed to 2450 MHz continuous wave radiofrequency radiation for 12 hours per day across four generations. The researchers examined fetal brain development, histopathological changes in female rats, and hippocampal MAPK protein levels in male rats. In exposed groups, hemorrhagic areas, irregular cellular localization, and vascular structures were observed in the brains of fetal and adult female rats across all generations. In adult male rats, phosphorylated ERK, tau, JNK, and p38 were significantly increased in the brain across all generations.

Exposure to 1800 MHz LTE electromagnetic fields under proinflammatory conditions decreases the response strength and increases the acoustic threshold of auditory cortical neurons

Unknown authors · 2022

Researchers exposed rats to 1800 MHz LTE electromagnetic fields for 2 hours under acute neuroinflammation induced by lipopolysaccharide. The mean specific absorption rate in the auditory cortex was 0.5 W/kg. Exposure reduced neuronal response strength to pure tones and natural vocalizations and increased acoustic thresholds at low and medium frequencies, while microglial coverage did not change. In healthy rats without neuroinflammation, the same exposure did not alter response strength or acoustic thresholds.

Effects of mobile phone electromagnetic radiation on rat hippocampus proteome

Unknown authors · 2022

The study performed global proteome profiling of rat hippocampus exposed to mobile phone radiation for 20 weeks, 3 hours per day, 5 days per week. They identified 358 hippocampus proteins, of which 16 were deregulated with log2 fold change ≥ ±1.0 and p-value <.05. Four proteins (Aldh5a1, Atp1b2, PMCA, S100B) representing each pathway were validated by western blot in an independent sample set, confirming the mass spectrometry results. The researchers concluded that mobile phone radiation exposure deregulates the hippocampus proteome, which might influence healthy brain functioning.

Changes in the excitability of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields

Unknown authors · 2022

The study investigated changes in neuronal activity and synaptic transmission after a 60-minute exposure to 3.0 GHz RF-EMF at a low dose (SAR < 1 W/kg). RF-EMF exposure decreased the amplitude of action potentials, depolarized resting membrane potential, and increased neuronal excitability and synaptic transmission in cultured primary hippocampal neurons.

Estimated all-day and evening whole-brain radiofrequency electromagnetic fields doses, and sleep in preadolescents

Unknown authors · 2022

Researchers estimated all-day and evening whole-brain radiofrequency electromagnetic field doses from phone calls, screen activities, and far-field sources in preadolescents aged 9 to 12 years from two birth cohorts. Sleep disturbances were assessed via a maternal questionnaire and objective sleep measures were recorded using wrist accelerometers and sleep diaries for seven consecutive days. All-day whole-brain RF-EMF doses were not associated with self-reported sleep disturbances or objective sleep measures, while high evening whole-brain RF-EMF dose from phone calls was associated with 11.9 minutes less total sleep time.

Microwave radiation induces neuronal autophagy through miR-30a-5p/AMPKα2 signal pathway

Unknown authors · 2022

Researchers exposed rat hippocampal neurons and PC12-derived neuron-like cells to 30 mW/cm2 microwaves, which down-regulated miR-30a and activated autophagy in vivo and in vitro. Bioinformatics analysis identified several potential miR-30a targets, and the team selected Prkaa2 for further study because prior work linked microwave radiation to abnormal energy metabolism in neurons. Dual-luciferase assays confirmed Prkaa2 as a downstream gene of miR-30a, and microwave exposure increased AMPKα2 expression and AMPKα Thr172 phosphorylation, while miR-30a mimics reversed these changes and blocked autophagy.

What is the radiation before 5G? A correlation study between measurements in situ and in real time and epidemiological indicators in Vallecas, Madrid

Isabel López et al. · 2021

Researchers surveyed 268 residents in a Madrid neighborhood surrounded by nine telephone antennas and took 105 electromagnetic radiation measurements with a spectrum analyzer and isotropic antenna both outside and inside homes. The study found statistically significant associations between radiation exposure and headaches, nightmares, dizziness, instability episodes, sleep duration, and tiredness parameters. Cancer prevalence in the study population was 5.6%, which is 10 times higher than the general Spanish population.

(2021) Effects of electromagnetic fields on neuronal ion channels: a systematic review

Bertagna et al · 2021

The review systematically examined published evidence from the last two decades on EMF effects on neuronal ion channels per PRISM guidelines. The review included 22 papers identified from searches of three online databases. Changes in calcium homeostasis linked to voltage-gated calcium channels were the most frequently reported outcome of EMF exposure. The authors reported that EMF effects on neurons vary widely and depend on field frequency, exposure duration, and tissue properties such as voltage-gated channel expression.

Brain & Nervous System
Not an original health-effects study

Occupational Exposure to Extremely Low-Frequency Magnetic Fields and Risk of Amyotrophic Lateral Sclerosis: Results of a Feasibility Study for a Pooled Analysis of Original Data

Unknown authors · 2021

Researchers conducted a systematic literature search in PubMed and EMF-Portal through January 2019 and identified 15 articles published between 1997 and 2019. Eight principal investigators expressed willingness to provide their original data for a pooled analysis. A pooled study would have more than 80% power to detect a relative risk of 1.14 or higher for ALS and occupational ELF-MF exposure.

1,800 MHz Radiofrequency Electromagnetic Irradiation Impairs Neurite Outgrowth With a Decrease in Rap1-GTP in Primary Mouse Hippocampal Neurons and Neuro2a Cells

Unknown authors · 2021

Researchers exposed primary hippocampal neurons from C57BL/6 mice and Neuro2a cells to 1,800 MHz RF-EMR at a specific absorption rate (SAR) value of 4 W/kg for 48 h. Exposure to 1,800 MHz RF-EMR for 24, 48, and 72 h at 4 W/kg did not influence cell viability. The neurite length, primary and secondary neurite numbers, and branch points of primary mouse hippocampal neurons were significantly impaired by 48-h RF-EMR exposure. The neurite-bearing cell percentage and neurite length of Neuro2a cells were also inhibited by 48-h RF-EMR exposure.

No Significant Effects of Cellphone Electromagnetic Radiation on Mice Memory or Anxiety: Some Mixed Effects on Traumatic Brain Injured Mice

Unknown authors · 2021

The study examined the effects of cellular radiation on male and female mice, assessing anxiety, spatial memory, and general well-being. Radiation alone did not significantly change anxiety levels or spatial/visual memory. In mice with mild traumatic brain injury, radiation improved visual memory in both sexes but worsened spatial memory in females.

Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures

Unknown authors · 2021

Researchers exposed primary human brain cultures at day 7 to 64 MHz electromagnetic fields for one hour daily over 14 days. This treatment significantly lowered secreted Aβ40 and Aβ42 peptide levels compared to untreated cultures. Similar reductions were also observed with one or two hours of daily exposure over 14 days, and with 4 or 8 days of exposure in cultures at a later stage. The minimum specific absorption rate needed for a biological effect was 0.4 W/kg. Exposure did not cause cellular toxicity or change sAPPα levels, indicating the Aβ reduction was not due to a shift to the α-secretase pathway.

Effects of Long‐Term Exposure of Intermediate Frequency Magnetic Fields (20 kHz, 360 μT) on the Development, Pathological Findings, and Behavior of Female Mice

Unknown authors · 2021

Researchers exposed female mice to 20 kHz, 360 μT magnetic fields or sham continuously from 3 months of age in a blind design. Body mass development and survival rates did not differ between groups. Tumor incidence rates also showed no significant differences. The 8-arm maze test revealed no significant differences, but exposed mice had longer retention times on the Rotarod test. In the open field test, exposed mice had significantly fewer supported rears.

The Effect of GSM Electromagnetic Field Exposure on the Waking Electroencephalogram: Methodological Influences

Dalecki A, Verrender A, · 2021

Thirty-six adults participated in three experimental sessions with sham, low (1 W/kg), and high (2 W/kg) RF-EMF exposures. Resting EEG was recorded at baseline, during, and after exposure. Alpha power increase was greater for eyes open than eyes closed during both low and high exposures. There was also a trend for the increase to be larger at the end of the high exposure compared to the start.

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